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The map label for this gene is ribH [H]

Identifier: 89255518

GI number: 89255518

Start: 72282

End: 72725

Strand: Reverse

Name: ribH [H]

Synonym: FTL_0075

Alternate gene names: 89255518

Gene position: 72725-72282 (Counterclockwise)

Preceding gene: 89255519

Following gene: 89255517

Centisome position: 3.84

GC content: 35.36

Gene sequence:

>444_bases
ATGAGAAAATTAGCAATCGTTGTAAGTGAATTTAACTCTTTGATAACTGATAAAATGCTTGAGGGTGCATTAGAAGAAGC
ATATGCTCAAGGCTTAAAAGATAGTCAAATTTGTATCAAAAAAGTTACTGGAGCAGTTGAACTTCCATATGCAGCAAAGC
TCCTAGCAGAAACTAAAGAGTTTGATGCAATAGTATTACTAGGTTGCGTAATCCGAGGCGAGACAGATCACTATGATTAT
GTTTGCGATCAGGTAAGTTATGGTACACAAAAAGTCATGCACCAATATAATTTACCAGTAATTTTTGGTATATTAACCAC
ACACAACAAAGAGCAAGCCTTAGAAAGAGTCGGTGGCAAAAAAGGTCATAAAGGTAAATACTCTATCCAAGCTGCCATAA
CGATGGCAAAGATGAAAAAAGATATTTTAGAACAAGGAGTATGA

Upstream 100 bases:

>100_bases
AGTATATTGTGAGGCATTTGTAAACTCTCACAATAGAAACTACTTGATAACTAAAAAAATTAAAGCAAAACATACAATTA
AAGGAATATAGGTATAAATT

Downstream 100 bases:

>100_bases
ATATGTCTTTAGAAATTCTAAAGTACCCTCACCCAGTTTTAAAAGAGGTTGCTAAAGAAGTTACAAAAGATGAAATCAAT
GATGATTTACGTGCAACTAT

Product: riboflavin synthase beta subunit (6,7-dimethl-8-ribityllumazine synthase)

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MRKLAIVVSEFNSLITDKMLEGALEEAYAQGLKDSQICIKKVTGAVELPYAAKLLAETKEFDAIVLLGCVIRGETDHYDY
VCDQVSYGTQKVMHQYNLPVIFGILTTHNKEQALERVGGKKGHKGKYSIQAAITMAKMKKDILEQGV

Sequences:

>Translated_147_residues
MRKLAIVVSEFNSLITDKMLEGALEEAYAQGLKDSQICIKKVTGAVELPYAAKLLAETKEFDAIVLLGCVIRGETDHYDY
VCDQVSYGTQKVMHQYNLPVIFGILTTHNKEQALERVGGKKGHKGKYSIQAAITMAKMKKDILEQGV
>Mature_147_residues
MRKLAIVVSEFNSLITDKMLEGALEEAYAQGLKDSQICIKKVTGAVELPYAAKLLAETKEFDAIVLLGCVIRGETDHYDY
VCDQVSYGTQKVMHQYNLPVIFGILTTHNKEQALERVGGKKGHKGKYSIQAAITMAKMKKDILEQGV

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=141, Percent_Identity=43.2624113475177, Blast_Score=117, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324429, Length=143, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16294; Mature: 16294

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLAIVVSEFNSLITDKMLEGALEEAYAQGLKDSQICIKKVTGAVELPYAAKLLAETKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
FDAIVLLGCVIRGETDHYDYVCDQVSYGTQKVMHQYNLPVIFGILTTHNKEQALERVGGK
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHCCC
KGHKGKYSIQAAITMAKMKKDILEQGV
CCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKLAIVVSEFNSLITDKMLEGALEEAYAQGLKDSQICIKKVTGAVELPYAAKLLAETKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
FDAIVLLGCVIRGETDHYDYVCDQVSYGTQKVMHQYNLPVIFGILTTHNKEQALERVGGK
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHCCC
KGHKGKYSIQAAITMAKMKKDILEQGV
CCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA