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The map label for this gene is prpC [H]

Identifier: 89056634

GI number: 89056634

Start: 4253345

End: 4254232

Strand: Direct

Name: prpC [H]

Synonym: Jann_4143

Alternate gene names: 89056634

Gene position: 4253345-4254232 (Clockwise)

Preceding gene: 89056633

Following gene: 89056635

Centisome position: 98.5

GC content: 62.39

Gene sequence:

>888_bases
ATGACTGATGCGCTGAAAAGTGAGTATGACGTCGCCTCGATTCTCTCCGTCGGGGCGCGGGAGCGGCAAGAGGATGCGGT
AGCCGTCGCCTTCCCTGATCGCACGGACCTCGGCTTTGCAGTTCTGTCAGACGGTATGGGCGGCCACGCCGCCGGCGACC
TTGCCAGTCGCGCCATCGTGGCGGAAATGTTCGCGTCTCTGACCCTGCGCGAGGCCACTGCCGCGACCCCGATCCCCGAG
ATTCTATGCGGCGCGGTTCGTCGCGCGAACGAAGGTGTGAAAGCGTGTATCGAGGCCAGTCCAGATCACGGCGGCATGGG
CGGAACCGTCGTCGCTACGCAAATTTCAGGCGACAAACTGCATTGGATCTCTGTCGGCGATTCGGTTCTTTACCTGTTTC
GTGACCAAAAGCTGAGACGCCTGAATGCGGATCACTCGATGGCCCCGCAGCTTGACCTCATGGTGGCCAAGGGTGCCATG
ACCCAGGCCGAGGCCGAGGCCCATCCGCAGCGCAACTGCCTGACCTCGGCCATCACGGGCGGGCCTATCGACGAAGTGGA
TTGTCCGGACCGACCCATCGTTCTGGAGCACGACGATATCGTGCTCCAGGCCAGTGACGGCCTGCAATTTTTGCCCGACC
CGATTATCGAAGCCCTCCTTCTGCGCGCACGCAACAACAGCAGCCAGCAGATTGCGCGCGATCTGATGGACGCGTTGGAT
ACCCTGAATGACCCTGAGCAGGACAACACGTCCATTGTGGTGATCCGCGCCAATGCTCCCGGCCGCCAATCACGGAAAGG
GATACTCGGCCGCGGATCGGGTGCCATGGTGAAAGCACTCCGTCGCGCCGTGAAACCCGCCGTCGTCCCGGCACCGGGAC
AAAGCTGA

Upstream 100 bases:

>100_bases
CACGGCGACACGATCCGCATCGGCAAAACCTCTTTGCGGTTCCACGCCTTCTGCGGTGCTGATTTCACCTGGGATCATGA
GGACGAAGGGGATGTCGCCC

Downstream 100 bases:

>100_bases
CGATGCACGCGCTGCACCCCAACTCAGAAGACGCCCTTGCGCAGCTTGGATTGCTGGCGAAGTCTGACAGGCTTCCGGCG
CGGGAAGCGGCGCGGTGCGC

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTDALKSEYDVASILSVGARERQEDAVAVAFPDRTDLGFAVLSDGMGGHAAGDLASRAIVAEMFASLTLREATAATPIPE
ILCGAVRRANEGVKACIEASPDHGGMGGTVVATQISGDKLHWISVGDSVLYLFRDQKLRRLNADHSMAPQLDLMVAKGAM
TQAEAEAHPQRNCLTSAITGGPIDEVDCPDRPIVLEHDDIVLQASDGLQFLPDPIIEALLLRARNNSSQQIARDLMDALD
TLNDPEQDNTSIVVIRANAPGRQSRKGILGRGSGAMVKALRRAVKPAVVPAPGQS

Sequences:

>Translated_295_residues
MTDALKSEYDVASILSVGARERQEDAVAVAFPDRTDLGFAVLSDGMGGHAAGDLASRAIVAEMFASLTLREATAATPIPE
ILCGAVRRANEGVKACIEASPDHGGMGGTVVATQISGDKLHWISVGDSVLYLFRDQKLRRLNADHSMAPQLDLMVAKGAM
TQAEAEAHPQRNCLTSAITGGPIDEVDCPDRPIVLEHDDIVLQASDGLQFLPDPIIEALLLRARNNSSQQIARDLMDALD
TLNDPEQDNTSIVVIRANAPGRQSRKGILGRGSGAMVKALRRAVKPAVVPAPGQS
>Mature_294_residues
TDALKSEYDVASILSVGARERQEDAVAVAFPDRTDLGFAVLSDGMGGHAAGDLASRAIVAEMFASLTLREATAATPIPEI
LCGAVRRANEGVKACIEASPDHGGMGGTVVATQISGDKLHWISVGDSVLYLFRDQKLRRLNADHSMAPQLDLMVAKGAMT
QAEAEAHPQRNCLTSAITGGPIDEVDCPDRPIVLEHDDIVLQASDGLQFLPDPIIEALLLRARNNSSQQIARDLMDALDT
LNDPEQDNTSIVVIRANAPGRQSRKGILGRGSGAMVKALRRAVKPAVVPAPGQS

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 31230; Mature: 31099

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDALKSEYDVASILSVGARERQEDAVAVAFPDRTDLGFAVLSDGMGGHAAGDLASRAIV
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHEECCCCCCCHHHHHHHHHHH
AEMFASLTLREATAATPIPEILCGAVRRANEGVKACIEASPDHGGMGGTVVATQISGDKL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEEECCCEE
HWISVGDSVLYLFRDQKLRRLNADHSMAPQLDLMVAKGAMTQAEAEAHPQRNCLTSAITG
EEEEECCEEEEEEHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCHHHHHHHHCCC
GPIDEVDCPDRPIVLEHDDIVLQASDGLQFLPDPIIEALLLRARNNSSQQIARDLMDALD
CCCCCCCCCCCCEEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLNDPEQDNTSIVVIRANAPGRQSRKGILGRGSGAMVKALRRAVKPAVVPAPGQS
HCCCCCCCCCEEEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDALKSEYDVASILSVGARERQEDAVAVAFPDRTDLGFAVLSDGMGGHAAGDLASRAIV
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHEECCCCCCCHHHHHHHHHHH
AEMFASLTLREATAATPIPEILCGAVRRANEGVKACIEASPDHGGMGGTVVATQISGDKL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEEECCCEE
HWISVGDSVLYLFRDQKLRRLNADHSMAPQLDLMVAKGAMTQAEAEAHPQRNCLTSAITG
EEEEECCEEEEEEHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCHHHHHHHHCCC
GPIDEVDCPDRPIVLEHDDIVLQASDGLQFLPDPIIEALLLRARNNSSQQIARDLMDALD
CCCCCCCCCCCCEEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLNDPEQDNTSIVVIRANAPGRQSRKGILGRGSGAMVKALRRAVKPAVVPAPGQS
HCCCCCCCCCEEEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]