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The map label for this gene is ompR [H]

Identifier: 89056505

GI number: 89056505

Start: 4118281

End: 4118985

Strand: Direct

Name: ompR [H]

Synonym: Jann_4014

Alternate gene names: 89056505

Gene position: 4118281-4118985 (Clockwise)

Preceding gene: 89056504

Following gene: 89056506

Centisome position: 95.38

GC content: 65.39

Gene sequence:

>705_bases
ATGACAGACGCCCCCTTGGTGAGCATTCTGGATGACGAGCCGCAGATCCGCGCCATGCTGTCGGAGGCGTTGACGGATGC
CGGGTTTCGCACCGCCACCTACGCCCGCGCCACGGAGTTTGAGGCCGCCCTGCGCCACACCACGCCGGATGTGTGCCTCG
TGGATCTGGGCCTGCCGGACCGCGACGGTCTGGCCGTCGTCCACCGTCTGGCGCTCGAATCCGGCGCCGCGATCATCATC
ATTTCGGGCCGCGCGCAGGTGCAGGATCGCGTGACGGGACTGGAACTGGGGGCGGACGATTACATCATCAAGCCGTTCGA
TCCGGCCGAGGTCATCGCCCGCGTCCGCGCCCGACTGCGCAGCCCCAAAACGCCCGAGCGGTCCCAGAATACCGCCCAGT
TCAACGGTTGGACCGCGCAATTCGACAGCTACGTCCTGACGGACAGGGATGGCGTCGAGACGCCCTTTTCCCACGCCGAA
GGGGAGGTGTTGCGCCTCTTCCTGAACGCGCCCAAACGCCTGATCTCGCGCCAGCATATGCAGGAAACCCTTGGCGGTGC
GGCGGGCGACAGCTTTGACCGCGCGATGGATGTCCGCATCTCTCGCCTGCGCACGAAACTGGGCGAGGACCCGAAAAATC
CGCGCCTGATCAAGACGATCTACGGGGCGGGCTATATCTTTCTGGGGGACGTGACTTGGTCGTAG

Upstream 100 bases:

>100_bases
ATGATCCGCTGTTCATGGCGGGGGCGGCCCGCTGGCCGGTCCTGCGCAAACCCATCGACGTCAGCGCCCTCGCGGCCTTG
TTGATGACGGAGGTCACCCC

Downstream 100 bases:

>100_bases
GCGACGGCGGGTTTGCCTGCTAGCGTCGCCCCGGTCGTAGCCAGGCGGGAGCCCCCATGCATCTCTGGATCCGAGCGGAA
GAGCGCGCCAATGAACGGCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTDAPLVSILDDEPQIRAMLSEALTDAGFRTATYARATEFEAALRHTTPDVCLVDLGLPDRDGLAVVHRLALESGAAIII
ISGRAQVQDRVTGLELGADDYIIKPFDPAEVIARVRARLRSPKTPERSQNTAQFNGWTAQFDSYVLTDRDGVETPFSHAE
GEVLRLFLNAPKRLISRQHMQETLGGAAGDSFDRAMDVRISRLRTKLGEDPKNPRLIKTIYGAGYIFLGDVTWS

Sequences:

>Translated_234_residues
MTDAPLVSILDDEPQIRAMLSEALTDAGFRTATYARATEFEAALRHTTPDVCLVDLGLPDRDGLAVVHRLALESGAAIII
ISGRAQVQDRVTGLELGADDYIIKPFDPAEVIARVRARLRSPKTPERSQNTAQFNGWTAQFDSYVLTDRDGVETPFSHAE
GEVLRLFLNAPKRLISRQHMQETLGGAAGDSFDRAMDVRISRLRTKLGEDPKNPRLIKTIYGAGYIFLGDVTWS
>Mature_233_residues
TDAPLVSILDDEPQIRAMLSEALTDAGFRTATYARATEFEAALRHTTPDVCLVDLGLPDRDGLAVVHRLALESGAAIIII
SGRAQVQDRVTGLELGADDYIIKPFDPAEVIARVRARLRSPKTPERSQNTAQFNGWTAQFDSYVLTDRDGVETPFSHAEG
EVLRLFLNAPKRLISRQHMQETLGGAAGDSFDRAMDVRISRLRTKLGEDPKNPRLIKTIYGAGYIFLGDVTWS

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=33.9130434782609, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=29.9145299145299, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.3275862068966, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=34.7639484978541, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=29.8245614035088, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=31.25, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=32.3144104803493, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=30.9090909090909, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=29.0178571428571, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.2511210762332, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=24.7863247863248, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=28.2511210762332, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=25.764192139738, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=32.5757575757576, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=140, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25810; Mature: 25678

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAPLVSILDDEPQIRAMLSEALTDAGFRTATYARATEFEAALRHTTPDVCLVDLGLPD
CCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
RDGLAVVHRLALESGAAIIIISGRAQVQDRVTGLELGADDYIIKPFDPAEVIARVRARLR
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHEEECCCCEEECCCCHHHHHHHHHHHHC
SPKTPERSQNTAQFNGWTAQFDSYVLTDRDGVETPFSHAEGEVLRLFLNAPKRLISRQHM
CCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHH
QETLGGAAGDSFDRAMDVRISRLRTKLGEDPKNPRLIKTIYGAGYIFLGDVTWS
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECEECC
>Mature Secondary Structure 
TDAPLVSILDDEPQIRAMLSEALTDAGFRTATYARATEFEAALRHTTPDVCLVDLGLPD
CCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
RDGLAVVHRLALESGAAIIIISGRAQVQDRVTGLELGADDYIIKPFDPAEVIARVRARLR
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHEEECCCCEEECCCCHHHHHHHHHHHHC
SPKTPERSQNTAQFNGWTAQFDSYVLTDRDGVETPFSHAEGEVLRLFLNAPKRLISRQHM
CCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHH
QETLGGAAGDSFDRAMDVRISRLRTKLGEDPKNPRLIKTIYGAGYIFLGDVTWS
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]