Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 89056504

GI number: 89056504

Start: 4116374

End: 4118284

Strand: Direct

Name: zraS [C]

Synonym: Jann_4013

Alternate gene names: 89056504

Gene position: 4116374-4118284 (Clockwise)

Preceding gene: 89056491

Following gene: 89056505

Centisome position: 95.33

GC content: 66.04

Gene sequence:

>1911_bases
ATGGCACGCGATCCCAAAACCGATACCTTCACCCGCGCAGGCCTCAACCTGATCCAGCAGGCGCTGTCGATCTACGATGC
GGATCTGCGGCTGGCTGTGTCCAATCGCCCGTTCCAGGAGATGTTCGACCTGCCCCGGCACCTCGTCACCCCCGGCGCGC
GGTTCGACGAGACCATCGCCTATCTGGTCGCCCGCGGTGAATATGGGGAGGTGGAGGATGAGGCGAGTTTCGTGCAGACC
CGTGTCGATCAGGCGCTGGCCTTCGTGCCCCATTATCTGGAACGGGTCCGCGCCAATGGTCGCGCGATTTCCATCGAAGG
CTCCCCCCTGCCCGAGGGCGGCTGGGTCACCGTCTACACCGACATCACTGCCGTCAAACGGCAGGAGGCGCTTTTGCGCG
CCCGGTCCGAGGAGCTGTCGGATCAGGTTCTGAGCCACACCGAAGAACTGGCCCTGACCAACCGCCGTCTGGAAGCCACG
ATCAGCCAGTTGCAGGAGGCCAAAGCCACCGTCGGAGAGATGGAGGCCCGCACCCGTCTGGTGACCGAGATGACGCCCGC
CCATATCGCCCATATCGACGCGCGCGGCATCTATACCTTCACCAACCGCCGCCTGTCCTCGCTGCTTCAGGGGCGCGCGA
ATGATATCATCGGCCTCAGCTTTGAGGAGGCGTTGGGCGAAGACACCGCCGCCCTCCTCCGCCCCACCCTTGCGCGCGCC
AGTGCGGGGGAGCCTGCGGTGCTGGAATTCTCGGAACCCGCATCGGGCCGCCGCATCCGCACGGCCTTCACGCCAGATGA
GCATTCAGACGGCGGCGTCTATCTTCTGTCCACCGATGTCACCCAGGAAACCCAGGCCCGCACCGCGCTGGAGCAAACCC
ATAAACGAGAACTCGCGGCGCAGCTGACCAGCGGCCTCGCCCATGACTTCGCCAACCTGCTGACGATTATTCTGGGCCTG
CAGGCGCGGCTGGAAAAACTGCCCCTGCCCCATGGCGCCCATGAATTGACGGGGGCGACCCGGATGGCGGTGCGGCGCGG
GGGGCTTCTGCTGGACAAGATCGCCAACATGACCAGCACCCGGGAGATCCGCGCAGCCCCCGTCGTGGTGCAGGATTTCC
TTGCCGGGTTCACGCCTCTGGCCCAGGCCACGCTGCCCGATGCCGTCGCCCTGTCGGTGCGGTGCAACGTGGCCCACACT
GCCCTGATGCTGGATGCCGGGTCCCTGCAAGATGGGCTGTTGAACCTTGTCCTGAACGCCCGCGACGGGATCGGTGCGGA
GGAGGGGCAAATCACGCTGATCCTGCAGGACGTCAAGGACACCTGGCTGGAAATCACGGTGGAGGACACCGGGCGCGGCT
TTTCCGACGCCGCCTTGGATCAGGCGCTGAACCCGTTTTTCACCACCAAAGGGGATGAGGGGTCGGGCCTGGGCCTCACC
ATGGTCTATGATCTTGTGAAGCTCGCGGGCGGCACCCTGCGCCTGTCCAATTCAGCAAGTGGCGCGCGCGTCATGCTGCG
GCTGCCCCTGCGTCCCGCTCAGGCCGATGCGCGCCCCCGTCTGATCCTTCTGGTTGACGATATGTCCGAGATCCGCGCGC
AGGTCCGTGACCTGCTGACCGACCTGGGCCATCAGGTGATCGAGGCCGCAACGGCGGAGGAGGCGCAAACGCTGGCCGAT
CTGCCGGGCCTCGACTGGGTCCTGTCGGATATCCATCTGGGTGAAGTCGACGGCGTTGCCGTCCTGGGCCACATCGCGGA
CCGCCACCCCGCCCTGCGCCTGTCGCTGATGACATCCCTGCCGCCCGATGATCCGCTGTTCATGGCGGGGGCGGCCCGCT
GGCCGGTCCTGCGCAAACCCATCGACGTCAGCGCCCTCGCGGCCTTGTTGATGACGGAGGTCACCCCATGA

Upstream 100 bases:

>100_bases
TGTCGGTCAAGCGTTACCTGACTTTTTCGCAAACCTTACGAATTGTAACAGGCCGGATGGGGGCCTTGGCGCGGGGCGAT
CAGGCGGCTAGCCATGGGAT

Downstream 100 bases:

>100_bases
CAGACGCCCCCTTGGTGAGCATTCTGGATGACGAGCCGCAGATCCGCGCCATGCTGTCGGAGGCGTTGACGGATGCCGGG
TTTCGCACCGCCACCTACGC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MARDPKTDTFTRAGLNLIQQALSIYDADLRLAVSNRPFQEMFDLPRHLVTPGARFDETIAYLVARGEYGEVEDEASFVQT
RVDQALAFVPHYLERVRANGRAISIEGSPLPEGGWVTVYTDITAVKRQEALLRARSEELSDQVLSHTEELALTNRRLEAT
ISQLQEAKATVGEMEARTRLVTEMTPAHIAHIDARGIYTFTNRRLSSLLQGRANDIIGLSFEEALGEDTAALLRPTLARA
SAGEPAVLEFSEPASGRRIRTAFTPDEHSDGGVYLLSTDVTQETQARTALEQTHKRELAAQLTSGLAHDFANLLTIILGL
QARLEKLPLPHGAHELTGATRMAVRRGGLLLDKIANMTSTREIRAAPVVVQDFLAGFTPLAQATLPDAVALSVRCNVAHT
ALMLDAGSLQDGLLNLVLNARDGIGAEEGQITLILQDVKDTWLEITVEDTGRGFSDAALDQALNPFFTTKGDEGSGLGLT
MVYDLVKLAGGTLRLSNSASGARVMLRLPLRPAQADARPRLILLVDDMSEIRAQVRDLLTDLGHQVIEAATAEEAQTLAD
LPGLDWVLSDIHLGEVDGVAVLGHIADRHPALRLSLMTSLPPDDPLFMAGAARWPVLRKPIDVSALAALLMTEVTP

Sequences:

>Translated_636_residues
MARDPKTDTFTRAGLNLIQQALSIYDADLRLAVSNRPFQEMFDLPRHLVTPGARFDETIAYLVARGEYGEVEDEASFVQT
RVDQALAFVPHYLERVRANGRAISIEGSPLPEGGWVTVYTDITAVKRQEALLRARSEELSDQVLSHTEELALTNRRLEAT
ISQLQEAKATVGEMEARTRLVTEMTPAHIAHIDARGIYTFTNRRLSSLLQGRANDIIGLSFEEALGEDTAALLRPTLARA
SAGEPAVLEFSEPASGRRIRTAFTPDEHSDGGVYLLSTDVTQETQARTALEQTHKRELAAQLTSGLAHDFANLLTIILGL
QARLEKLPLPHGAHELTGATRMAVRRGGLLLDKIANMTSTREIRAAPVVVQDFLAGFTPLAQATLPDAVALSVRCNVAHT
ALMLDAGSLQDGLLNLVLNARDGIGAEEGQITLILQDVKDTWLEITVEDTGRGFSDAALDQALNPFFTTKGDEGSGLGLT
MVYDLVKLAGGTLRLSNSASGARVMLRLPLRPAQADARPRLILLVDDMSEIRAQVRDLLTDLGHQVIEAATAEEAQTLAD
LPGLDWVLSDIHLGEVDGVAVLGHIADRHPALRLSLMTSLPPDDPLFMAGAARWPVLRKPIDVSALAALLMTEVTP
>Mature_635_residues
ARDPKTDTFTRAGLNLIQQALSIYDADLRLAVSNRPFQEMFDLPRHLVTPGARFDETIAYLVARGEYGEVEDEASFVQTR
VDQALAFVPHYLERVRANGRAISIEGSPLPEGGWVTVYTDITAVKRQEALLRARSEELSDQVLSHTEELALTNRRLEATI
SQLQEAKATVGEMEARTRLVTEMTPAHIAHIDARGIYTFTNRRLSSLLQGRANDIIGLSFEEALGEDTAALLRPTLARAS
AGEPAVLEFSEPASGRRIRTAFTPDEHSDGGVYLLSTDVTQETQARTALEQTHKRELAAQLTSGLAHDFANLLTIILGLQ
ARLEKLPLPHGAHELTGATRMAVRRGGLLLDKIANMTSTREIRAAPVVVQDFLAGFTPLAQATLPDAVALSVRCNVAHTA
LMLDAGSLQDGLLNLVLNARDGIGAEEGQITLILQDVKDTWLEITVEDTGRGFSDAALDQALNPFFTTKGDEGSGLGLTM
VYDLVKLAGGTLRLSNSASGARVMLRLPLRPAQADARPRLILLVDDMSEIRAQVRDLLTDLGHQVIEAATAEEAQTLADL
PGLDWVLSDIHLGEVDGVAVLGHIADRHPALRLSLMTSLPPDDPLFMAGAARWPVLRKPIDVSALAALLMTEVTP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=28.1385281385281, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68985; Mature: 68854

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDPKTDTFTRAGLNLIQQALSIYDADLRLAVSNRPFQEMFDLPRHLVTPGARFDETIA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCHHHHCCCCCCHHHHHH
YLVARGEYGEVEDEASFVQTRVDQALAFVPHYLERVRANGRAISIEGSPLPEGGWVTVYT
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEE
DITAVKRQEALLRARSEELSDQVLSHTEELALTNRRLEATISQLQEAKATVGEMEARTRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTEMTPAHIAHIDARGIYTFTNRRLSSLLQGRANDIIGLSFEEALGEDTAALLRPTLARA
HHHCCCHHHEEECCCCEEEHHHHHHHHHHCCCCCCEEEECHHHHHCCCHHHHHHHHHHHC
SAGEPAVLEFSEPASGRRIRTAFTPDEHSDGGVYLLSTDVTQETQARTALEQTHKRELAA
CCCCCEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
QLTSGLAHDFANLLTIILGLQARLEKLPLPHGAHELTGATRMAVRRGGLLLDKIANMTST
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCC
REIRAAPVVVQDFLAGFTPLAQATLPDAVALSVRCNVAHTALMLDAGSLQDGLLNLVLNA
CHHHHCHHHHHHHHHCCCHHHHHCCCCCEEEEEEECHHHEEEEEECCCHHHHHHHHHHCC
RDGIGAEEGQITLILQDVKDTWLEITVEDTGRGFSDAALDQALNPFFTTKGDEGSGLGLT
CCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCCCEECCCCCCCCCHHH
MVYDLVKLAGGTLRLSNSASGARVMLRLPLRPAQADARPRLILLVDDMSEIRAQVRDLLT
HHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
DLGHQVIEAATAEEAQTLADLPGLDWVLSDIHLGEVDGVAVLGHIADRHPALRLSLMTSL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEHHCC
PPDDPLFMAGAARWPVLRKPIDVSALAALLMTEVTP
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARDPKTDTFTRAGLNLIQQALSIYDADLRLAVSNRPFQEMFDLPRHLVTPGARFDETIA
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCHHHHCCCCCCHHHHHH
YLVARGEYGEVEDEASFVQTRVDQALAFVPHYLERVRANGRAISIEGSPLPEGGWVTVYT
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEE
DITAVKRQEALLRARSEELSDQVLSHTEELALTNRRLEATISQLQEAKATVGEMEARTRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTEMTPAHIAHIDARGIYTFTNRRLSSLLQGRANDIIGLSFEEALGEDTAALLRPTLARA
HHHCCCHHHEEECCCCEEEHHHHHHHHHHCCCCCCEEEECHHHHHCCCHHHHHHHHHHHC
SAGEPAVLEFSEPASGRRIRTAFTPDEHSDGGVYLLSTDVTQETQARTALEQTHKRELAA
CCCCCEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
QLTSGLAHDFANLLTIILGLQARLEKLPLPHGAHELTGATRMAVRRGGLLLDKIANMTST
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCC
REIRAAPVVVQDFLAGFTPLAQATLPDAVALSVRCNVAHTALMLDAGSLQDGLLNLVLNA
CHHHHCHHHHHHHHHCCCHHHHHCCCCCEEEEEEECHHHEEEEEECCCHHHHHHHHHHCC
RDGIGAEEGQITLILQDVKDTWLEITVEDTGRGFSDAALDQALNPFFTTKGDEGSGLGLT
CCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCCCEECCCCCCCCCHHH
MVYDLVKLAGGTLRLSNSASGARVMLRLPLRPAQADARPRLILLVDDMSEIRAQVRDLLT
HHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
DLGHQVIEAATAEEAQTLADLPGLDWVLSDIHLGEVDGVAVLGHIADRHPALRLSLMTSL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEHHCC
PPDDPLFMAGAARWPVLRKPIDVSALAALLMTEVTP
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA