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The map label for this gene is pheA [H]

Identifier: 89056356

GI number: 89056356

Start: 3963307

End: 3964137

Strand: Direct

Name: pheA [H]

Synonym: Jann_3865

Alternate gene names: 89056356

Gene position: 3963307-3964137 (Clockwise)

Preceding gene: 89056350

Following gene: 89056359

Centisome position: 91.79

GC content: 60.05

Gene sequence:

>831_bases
ATGACGGACCGTATCGCCTTCCAGGGAGAGCCCGGCGCCTATTCCCATCAGGCCTGCCATGAGGCTCGCCCCAACCTCGA
AGCCCTGCCCTGTGCAAGCTTCGAGGATGTGATCGAGGCTGTCAGGGCCGGAGACGCGCAACAGGCGATGGTCCCGGTGG
AGAACTCAACCTACGGGCGTGTTGCGGACATCCACAGGCTTCTGCCCGAATCGGGTTTGCACATCGTGGACGAGGCATTC
GTACGCGTGCACATCAACCTTCTGGCGGTGCCTGGCGCGACGCTGGAAAACGTGACCGAGGCCCACAGCCACCTTGTTTT
ACTCCCCCAATGCAGCAAGTTTCTTGCGAAGAACGGGATCAAGGGCCGGGTCAGCAGCGACAATGCGCGCGCCGCGCGTG
ATGTGGCGGATTGGGCCGATCCGTCGAAGGCCGCGCTCGCTTCAGAGCTGGCCGGGGAGATCTACGGCCTCAACGCTCTG
GCCCGCCATATCGAGGATCATGACCGCAACACCACGCGGTTTCTGGTCATGGCACCGGACGCGGACATGACCCGACGCGC
GGAACGGATGATGACGACTTTCGTCTTTCGTGTCCGAAACATTCCTGCGGCACTATATAAAGCGATGGGTGGGTTTGCCA
CCAATAGTGTGAACATGACCAAGCTCGAATCATACATGGTTGACGGGTCATTCACCGCGACGCAGTTCTACTCGGACATC
GAAGGGCATCCCGATGACGCCAACGTTCAGCTTGCGATGGAAGAACTGGGATATTTCACAGACCAGCTAAAGATCCTCGG
CACCTATCCTGCCGATGCCGCCCGGGACTGA

Upstream 100 bases:

>100_bases
CACGGGAATGTCGCTGGTCTTGCGTATCTATTGTGTTCCGTCTGCCTATGGCAAGGTGTAGTCAGCGCGACGAAACGACC
TTTTTGCTTTGGATTTGCCT

Downstream 100 bases:

>100_bases
GCGCGGCTATCCGGCCGGTTCCGCCATCATTTCGGCAAACCACAGCCAGGCGTCTTCGGCGATGGCAGGGCCGCCCTCAT
AAAACCAATGGGTGTGGCCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTDRIAFQGEPGAYSHQACHEARPNLEALPCASFEDVIEAVRAGDAQQAMVPVENSTYGRVADIHRLLPESGLHIVDEAF
VRVHINLLAVPGATLENVTEAHSHLVLLPQCSKFLAKNGIKGRVSSDNARAARDVADWADPSKAALASELAGEIYGLNAL
ARHIEDHDRNTTRFLVMAPDADMTRRAERMMTTFVFRVRNIPAALYKAMGGFATNSVNMTKLESYMVDGSFTATQFYSDI
EGHPDDANVQLAMEELGYFTDQLKILGTYPADAARD

Sequences:

>Translated_276_residues
MTDRIAFQGEPGAYSHQACHEARPNLEALPCASFEDVIEAVRAGDAQQAMVPVENSTYGRVADIHRLLPESGLHIVDEAF
VRVHINLLAVPGATLENVTEAHSHLVLLPQCSKFLAKNGIKGRVSSDNARAARDVADWADPSKAALASELAGEIYGLNAL
ARHIEDHDRNTTRFLVMAPDADMTRRAERMMTTFVFRVRNIPAALYKAMGGFATNSVNMTKLESYMVDGSFTATQFYSDI
EGHPDDANVQLAMEELGYFTDQLKILGTYPADAARD
>Mature_275_residues
TDRIAFQGEPGAYSHQACHEARPNLEALPCASFEDVIEAVRAGDAQQAMVPVENSTYGRVADIHRLLPESGLHIVDEAFV
RVHINLLAVPGATLENVTEAHSHLVLLPQCSKFLAKNGIKGRVSSDNARAARDVADWADPSKAALASELAGEIYGLNALA
RHIEDHDRNTTRFLVMAPDADMTRRAERMMTTFVFRVRNIPAALYKAMGGFATNSVNMTKLESYMVDGSFTATQFYSDIE
GHPDDANVQLAMEELGYFTDQLKILGTYPADAARD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=274, Percent_Identity=33.9416058394161, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30238; Mature: 30107

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIAFQGEPGAYSHQACHEARPNLEALPCASFEDVIEAVRAGDAQQAMVPVENSTYGR
CCCCEEECCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCH
VADIHRLLPESGLHIVDEAFVRVHINLLAVPGATLENVTEAHSHLVLLPQCSKFLAKNGI
HHHHHHHCCCCCCHHHHHHHHEEEEEEEEECCCHHHHHHHHHHCEEECHHHHHHHHCCCC
KGRVSSDNARAARDVADWADPSKAALASELAGEIYGLNALARHIEDHDRNTTRFLVMAPD
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ADMTRRAERMMTTFVFRVRNIPAALYKAMGGFATNSVNMTKLESYMVDGSFTATQFYSDI
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHC
EGHPDDANVQLAMEELGYFTDQLKILGTYPADAARD
CCCCCCCCCEEHHHHHHHHHHHEEEEECCCCCCCCC
>Mature Secondary Structure 
TDRIAFQGEPGAYSHQACHEARPNLEALPCASFEDVIEAVRAGDAQQAMVPVENSTYGR
CCCEEECCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCH
VADIHRLLPESGLHIVDEAFVRVHINLLAVPGATLENVTEAHSHLVLLPQCSKFLAKNGI
HHHHHHHCCCCCCHHHHHHHHEEEEEEEEECCCHHHHHHHHHHCEEECHHHHHHHHCCCC
KGRVSSDNARAARDVADWADPSKAALASELAGEIYGLNALARHIEDHDRNTTRFLVMAPD
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ADMTRRAERMMTTFVFRVRNIPAALYKAMGGFATNSVNMTKLESYMVDGSFTATQFYSDI
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHC
EGHPDDANVQLAMEELGYFTDQLKILGTYPADAARD
CCCCCCCCCEEHHHHHHHHHHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]