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The map label for this gene is gsiC [H]

Identifier: 89056308

GI number: 89056308

Start: 3907401

End: 3908357

Strand: Direct

Name: gsiC [H]

Synonym: Jann_3817

Alternate gene names: 89056308

Gene position: 3907401-3908357 (Clockwise)

Preceding gene: 89056307

Following gene: 89056309

Centisome position: 90.49

GC content: 61.86

Gene sequence:

>957_bases
ATGTCACATATCTGGATAATGATCGCGCAGCGGCTGGCTCTTGGCCTTGTCACTCTGTTCGTGGTGTCATTGATCATCTT
CCTCGGCACCGAGCTTCTGCCCGGTGACTTCGCGCAGGAGATCCTTGGCCAATCCGCTACGCCTGAAACCGTCGCCGCCC
TGCGCGAGCAATTGGGCCTGAACGACTCGATGGTGACGCGATATGCCAACTGGCTGGGGGATGTGCTGCAAGGGGATCTG
GGGGAGAGTCTCGCCAACGGACAATCGGTGTCCGAACTGATCGGACGCCGCCTTGGCTGGACCCTGTCACTGGCGCTTTA
TGCGGCCGCCATCGCGGTGCCCTTGTCCCTGACCCTCGGCATCCTCGCAGCCCTCTTCCGCAACTCCTTCTTCGACCGCT
TCGCCAATGCCTCGGCGCTCACGTCGATCTCCTTCCCCGAATTCTTCGTCGCCTACATCCTTATCTTCTATCTGGCGGGC
GCAGGCGGGCCGTTCCCGTCGATCTCCAATATGCGCGGCGTGGAGGGGTTTGGCGATTACCTCTACCGCACCTTCCTGCC
CGCTTTGACGCTGACCTTGGTCGTCACCGCCCATATGATGCGGATGACGCGGGCCGCGATCATCAACCTTCTGGCGTCGC
CGTACATTGAAATGGCGCGGCTGAAGGGCATGTCGCCCATGCGCGTTGTGGTGAAACACGCGCTGCCCAATGCGCTGGCC
CCGATCATCAACGTGGTGGCCCTGAACCTTGCGTATCTGATCACCGGCGTCGTCGTGGTGGAGGTCGTCTTCGTCTACCC
CGGCCTTGGCCAGTTGATGGTTGATTCAGTGTCGGCCCGTGACATGCCGGTCGTCCAAGGCATCGCCCTTGTCTTCGCCG
CCGCCTACGTGCTGCTGAACCTCACCGCGGATGTGTTGGCGACCTTGTCCAACCCCCGCCTCGTGCACCGTCGCTGA

Upstream 100 bases:

>100_bases
TTGGTCGGGGGTTCTTCGTTCCGGAACGGGCACATAGGCCCGGGGAACCACAATCAAGAACAAAGCGGCCCTCAGACCGG
CCCGAAGGATAACCCCCGCC

Downstream 100 bases:

>100_bases
GGGGGGCTGGATATGGGATTTCTCATGGGATTGGTGTGGTTGGTTGGCGTCATCGTGGCGGCGATGGCTGCCGGGTGGAT
CTTTCGCCAGATCTTGGTTC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSHIWIMIAQRLALGLVTLFVVSLIIFLGTELLPGDFAQEILGQSATPETVAALREQLGLNDSMVTRYANWLGDVLQGDL
GESLANGQSVSELIGRRLGWTLSLALYAAAIAVPLSLTLGILAALFRNSFFDRFANASALTSISFPEFFVAYILIFYLAG
AGGPFPSISNMRGVEGFGDYLYRTFLPALTLTLVVTAHMMRMTRAAIINLLASPYIEMARLKGMSPMRVVVKHALPNALA
PIINVVALNLAYLITGVVVVEVVFVYPGLGQLMVDSVSARDMPVVQGIALVFAAAYVLLNLTADVLATLSNPRLVHRR

Sequences:

>Translated_318_residues
MSHIWIMIAQRLALGLVTLFVVSLIIFLGTELLPGDFAQEILGQSATPETVAALREQLGLNDSMVTRYANWLGDVLQGDL
GESLANGQSVSELIGRRLGWTLSLALYAAAIAVPLSLTLGILAALFRNSFFDRFANASALTSISFPEFFVAYILIFYLAG
AGGPFPSISNMRGVEGFGDYLYRTFLPALTLTLVVTAHMMRMTRAAIINLLASPYIEMARLKGMSPMRVVVKHALPNALA
PIINVVALNLAYLITGVVVVEVVFVYPGLGQLMVDSVSARDMPVVQGIALVFAAAYVLLNLTADVLATLSNPRLVHRR
>Mature_317_residues
SHIWIMIAQRLALGLVTLFVVSLIIFLGTELLPGDFAQEILGQSATPETVAALREQLGLNDSMVTRYANWLGDVLQGDLG
ESLANGQSVSELIGRRLGWTLSLALYAAAIAVPLSLTLGILAALFRNSFFDRFANASALTSISFPEFFVAYILIFYLAGA
GGPFPSISNMRGVEGFGDYLYRTFLPALTLTLVVTAHMMRMTRAAIINLLASPYIEMARLKGMSPMRVVVKHALPNALAP
IINVVALNLAYLITGVVVVEVVFVYPGLGQLMVDSVSARDMPVVQGIALVFAAAYVLLNLTADVLATLSNPRLVHRR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=311, Percent_Identity=37.620578778135, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789965, Length=335, Percent_Identity=33.4328358208955, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=35.2409638554217, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789888, Length=310, Percent_Identity=30, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787497, Length=309, Percent_Identity=30.42071197411, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1788504, Length=284, Percent_Identity=29.2253521126761, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787550, Length=279, Percent_Identity=24.7311827956989, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34329; Mature: 34198

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHIWIMIAQRLALGLVTLFVVSLIIFLGTELLPGDFAQEILGQSATPETVAALREQLGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCC
NDSMVTRYANWLGDVLQGDLGESLANGQSVSELIGRRLGWTLSLALYAAAIAVPLSLTLG
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAALFRNSFFDRFANASALTSISFPEFFVAYILIFYLAGAGGPFPSISNMRGVEGFGDY
HHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LYRTFLPALTLTLVVTAHMMRMTRAAIINLLASPYIEMARLKGMSPMRVVVKHALPNALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
PIINVVALNLAYLITGVVVVEVVFVYPGLGQLMVDSVSARDMPVVQGIALVFAAAYVLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LTADVLATLSNPRLVHRR
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SHIWIMIAQRLALGLVTLFVVSLIIFLGTELLPGDFAQEILGQSATPETVAALREQLGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCC
NDSMVTRYANWLGDVLQGDLGESLANGQSVSELIGRRLGWTLSLALYAAAIAVPLSLTLG
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAALFRNSFFDRFANASALTSISFPEFFVAYILIFYLAGAGGPFPSISNMRGVEGFGDY
HHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LYRTFLPALTLTLVVTAHMMRMTRAAIINLLASPYIEMARLKGMSPMRVVVKHALPNALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
PIINVVALNLAYLITGVVVVEVVFVYPGLGQLMVDSVSARDMPVVQGIALVFAAAYVLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LTADVLATLSNPRLVHRR
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]