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The map label for this gene is hmp [H]

Identifier: 89056230

GI number: 89056230

Start: 3821731

End: 3822990

Strand: Direct

Name: hmp [H]

Synonym: Jann_3739

Alternate gene names: 89056230

Gene position: 3821731-3822990 (Clockwise)

Preceding gene: 89056229

Following gene: 89056231

Centisome position: 88.51

GC content: 58.57

Gene sequence:

>1260_bases
ATGCTTCGCAAACAAGGACTGATCGCAATGGCCGTGGTCATTGGCCTATTCGTGGTGCTGCATCTGGGGTTCGCCCCGGA
CCATCACGCGCCGCGCACCACAGGCACTGTAATGCTGGGGGGCATCGCGTTTCTGCTGATGACCAGTTCGATCATTCTGT
CGACCCGGCTGCCGATCCTTGAAGATCTCTTTGGCGGTCTGGACCGCATGTATCAGGTGCACCGGGTTGCCGGTGTATTC
ACAGCCCTGTTCGCCCTGACCCATTTCTTTGCGGTCCCCAAGGACTTGCCAGAGGGTATCGACCCGGTCGCAAACGCGCT
TGTCCCATCGGCCCCAATGGGGATGCTCGGTTTGATCTTCTTGGTGATTGGCCTGTTCGTCGCCTTGAACCGGAAAATCC
GATACTCCCGCTGGCGGCCAACGCACAAGATCATGGGGGCGGTCTACATCCTGATCATTGGTCATTTCATGACCGCACCC
GGTATCTTTTTTGAGCGGTTCAGCGTGTCCGGCGTGATGTTGATCGTTACGGCCGTCATCGGTGTGGTTGCGCTGGTTTA
TTCTGTCTTCGGTATGAACAAACGCACGGCGCTGCCCTTCACGATCGAGGCTGTGAACGCGCTGGAGCGGGCGACAGAGG
TGGTGCTGAAGCCCAAGGCTGGCATGCTGGATTTCAAACCCGGCCAGTTTGCCTTTGTAGAAGTGCAGGGTAAGGGATGG
TCGGAACCCCACCCCTTCACCATCTCCAGCGCGCCGGCTGAGGACGGCGTTCGTTTCACCATGAAAGTGCTTGGCGATTG
GACGCGCAAGGTGCGCGAGGAACTGAAGCCGGGCGGCGAAGTTCTGGTGCGCGGGCCTTATGGCAGGTTCGATGCGGCCA
GCGCCGGAAACAAGCAAATCTGGCTGGCAGGCGGCATCGGCCTGACACCCTTCCTGTCGAAGCTTCGAGCGATGGAACCG
GGCGACCCGCGCAACATCCACCTCGTCTATGCCGCACGCGAGGAGCAGGACGCCATTTTCCTTGATGAGTTGAAAGCCCG
CGCGGCAGAGCTCGGGAACGTCAAACTGATCTCGCTTTTCTCAGACAACGGCGAGTTCGCGCGCGTCGATATCATGAAAC
AGAAGCTGCCTGATCCGCTTGGCACCTACGACTACTTCATGTGCGGGCCCAAGCCGATGATCGAGACGATCATGAAGGAT
CTCAAAGCCGAAGGCGTGGGCCGCAGCAAAATCCACACAGAGGCTTTTGAATTCAGATGA

Upstream 100 bases:

>100_bases
AAGAAGAGTTTCTGCACGGCTTCTCACTGCTGATCGCGGTGCGGGCGGCCATTGACCCAACCCCAGTCGAGTAATCGATC
ACCCAACGGAGGGGGCTGTC

Downstream 100 bases:

>100_bases
TCGCTATCTTGCTACCGATCCTCGAACTCGCCGTCCTTGCCGCCCTTGGGCTGATGGTGGGTGCGATGATCTACACCTCA
TTCGTCGAGATCCCGGTACG

Product: oxidoreductase FAD/NAD(P)-binding

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLRKQGLIAMAVVIGLFVVLHLGFAPDHHAPRTTGTVMLGGIAFLLMTSSIILSTRLPILEDLFGGLDRMYQVHRVAGVF
TALFALTHFFAVPKDLPEGIDPVANALVPSAPMGMLGLIFLVIGLFVALNRKIRYSRWRPTHKIMGAVYILIIGHFMTAP
GIFFERFSVSGVMLIVTAVIGVVALVYSVFGMNKRTALPFTIEAVNALERATEVVLKPKAGMLDFKPGQFAFVEVQGKGW
SEPHPFTISSAPAEDGVRFTMKVLGDWTRKVREELKPGGEVLVRGPYGRFDAASAGNKQIWLAGGIGLTPFLSKLRAMEP
GDPRNIHLVYAAREEQDAIFLDELKARAAELGNVKLISLFSDNGEFARVDIMKQKLPDPLGTYDYFMCGPKPMIETIMKD
LKAEGVGRSKIHTEAFEFR

Sequences:

>Translated_419_residues
MLRKQGLIAMAVVIGLFVVLHLGFAPDHHAPRTTGTVMLGGIAFLLMTSSIILSTRLPILEDLFGGLDRMYQVHRVAGVF
TALFALTHFFAVPKDLPEGIDPVANALVPSAPMGMLGLIFLVIGLFVALNRKIRYSRWRPTHKIMGAVYILIIGHFMTAP
GIFFERFSVSGVMLIVTAVIGVVALVYSVFGMNKRTALPFTIEAVNALERATEVVLKPKAGMLDFKPGQFAFVEVQGKGW
SEPHPFTISSAPAEDGVRFTMKVLGDWTRKVREELKPGGEVLVRGPYGRFDAASAGNKQIWLAGGIGLTPFLSKLRAMEP
GDPRNIHLVYAAREEQDAIFLDELKARAAELGNVKLISLFSDNGEFARVDIMKQKLPDPLGTYDYFMCGPKPMIETIMKD
LKAEGVGRSKIHTEAFEFR
>Mature_419_residues
MLRKQGLIAMAVVIGLFVVLHLGFAPDHHAPRTTGTVMLGGIAFLLMTSSIILSTRLPILEDLFGGLDRMYQVHRVAGVF
TALFALTHFFAVPKDLPEGIDPVANALVPSAPMGMLGLIFLVIGLFVALNRKIRYSRWRPTHKIMGAVYILIIGHFMTAP
GIFFERFSVSGVMLIVTAVIGVVALVYSVFGMNKRTALPFTIEAVNALERATEVVLKPKAGMLDFKPGQFAFVEVQGKGW
SEPHPFTISSAPAEDGVRFTMKVLGDWTRKVREELKPGGEVLVRGPYGRFDAASAGNKQIWLAGGIGLTPFLSKLRAMEP
GDPRNIHLVYAAREEQDAIFLDELKARAAELGNVKLISLFSDNGEFARVDIMKQKLPDPLGTYDYFMCGPKPMIETIMKD
LKAEGVGRSKIHTEAFEFR

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG4097

COG function: function code P; Predicted ferric reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 46075; Mature: 46075

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKQGLIAMAVVIGLFVVLHLGFAPDHHAPRTTGTVMLGGIAFLLMTSSIILSTRLPIL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
EDLFGGLDRMYQVHRVAGVFTALFALTHFFAVPKDLPEGIDPVANALVPSAPMGMLGLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCHHHHHHHH
LVIGLFVALNRKIRYSRWRPTHKIMGAVYILIIGHFMTAPGIFFERFSVSGVMLIVTAVI
HHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHH
GVVALVYSVFGMNKRTALPFTIEAVNALERATEVVLKPKAGMLDFKPGQFAFVEVQGKGW
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCC
SEPHPFTISSAPAEDGVRFTMKVLGDWTRKVREELKPGGEVLVRGPYGRFDAASAGNKQI
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEE
WLAGGIGLTPFLSKLRAMEPGDPRNIHLVYAAREEQDAIFLDELKARAAELGNVKLISLF
EEECCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEE
SDNGEFARVDIMKQKLPDPLGTYDYFMCGPKPMIETIMKDLKAEGVGRSKIHTEAFEFR
CCCCCEEEEEHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLRKQGLIAMAVVIGLFVVLHLGFAPDHHAPRTTGTVMLGGIAFLLMTSSIILSTRLPIL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
EDLFGGLDRMYQVHRVAGVFTALFALTHFFAVPKDLPEGIDPVANALVPSAPMGMLGLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCHHHHHHHH
LVIGLFVALNRKIRYSRWRPTHKIMGAVYILIIGHFMTAPGIFFERFSVSGVMLIVTAVI
HHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHH
GVVALVYSVFGMNKRTALPFTIEAVNALERATEVVLKPKAGMLDFKPGQFAFVEVQGKGW
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCC
SEPHPFTISSAPAEDGVRFTMKVLGDWTRKVREELKPGGEVLVRGPYGRFDAASAGNKQI
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEE
WLAGGIGLTPFLSKLRAMEPGDPRNIHLVYAAREEQDAIFLDELKARAAELGNVKLISLF
EEECCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEE
SDNGEFARVDIMKQKLPDPLGTYDYFMCGPKPMIETIMKDLKAEGVGRSKIHTEAFEFR
CCCCCEEEEEHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14521231; 11481432 [H]