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The map label for this gene is feaR [H]

Identifier: 89056227

GI number: 89056227

Start: 3819336

End: 3820349

Strand: Direct

Name: feaR [H]

Synonym: Jann_3736

Alternate gene names: 89056227

Gene position: 3819336-3820349 (Clockwise)

Preceding gene: 89056223

Following gene: 89056229

Centisome position: 88.45

GC content: 57.4

Gene sequence:

>1014_bases
ATGGCGCAGATATTTGAACTTAGCCGCGAAAAGCCCGTCAGGCGGGTGGAGGCTTGGCAAGATATCGTGTCCAGGACGTT
TGTGACGCTGGCCTGCGATCTTCCGGACAAAACTGACGTAACCGGGTCCATCGCCTCCATCGGAAACGGGCCGATATCCG
CCAGCCTCGTGGATTCCGTGGCCCAAACTGTGGATCGAACGCGCCGGCTGATCCGGCAAGATGATGCCGAGGTTGCTCTC
ATCAGTTTTCAGATTGAGGGGGAGTGCCTTCTTCAGCAGCGTGACCGTCAGGTGCGCTTGCGACCGGGAGACTTCACGAT
CTACGACAGCACCAGCCCCTATGATCTGCAGTTTGAGGAGGACTTCTGCCAGCTCGTCCTGCACATGCCGCGCGACCTGT
TGCGACGCCGGTTGGGGCCTGTGCGTCAGATCTGCGCGCAACGGTTTGGTTCAGATACCGGGGCCAATTCCTTTGCAGGT
GCCTATCTGAAACAGATCGCTCTGCAATTGACGTCTCTGGAGACCGCCACCGCCGAGCATCACATCAAGACAGCTTTGGA
TCTGGTTGGTTACGCTGTGGAGCAGAACGTTCAGCCCTGCGGCCATGATGTGAGGCGACAGTCCGCCGCGATCCGAGAGC
AGGTCGCACAGGTTATCAGCAAGCACTTCCGTGATGATCAACTGTCGACGCCCTCACTCGCACGAGCTGTCGGCATCTCC
TCCAGACGCCTGCAGGAGGTCTGTGCAGAGGTCGGAACCACTCCCATGAACGCGATCTGGGATATCCGGCTGGAAAAGGC
ATCTGACATGCTCCGAAGCCCCGCATTCGCGCATCTGTCCATTACGGACATCTGCTTTGCCTGTGGCTTTGGAGACTCGT
CGCAATTCAGTCGAAGATACAAGACGATGTACGGCGTTACACCAAGAGAGGACAGAAAATCCGGATATCGTAACGGGTTC
AGCGGTTCAGTGCAGACTCTTAGCAAAAGCGCGGGTCGCTTTCAGAGACGATAG

Upstream 100 bases:

>100_bases
GTCGCCGCAAATGGCCCTGCGGTCTTGGTGCTCTGCGTGATCGGATTTGGTTCTGCGCGCGGGTCTTTCATGCTAGCGTG
GTGCGGGGAGGCTGCGGATC

Downstream 100 bases:

>100_bases
AAGTCTCGGCTCAACCGGAAAGTGGGACCACCCACCTCTCGCAGTCCCATTGGATTGAGGATGTTTGCAGACCAGAATGA
GTGGTCGACGCTAAGCACTG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAQIFELSREKPVRRVEAWQDIVSRTFVTLACDLPDKTDVTGSIASIGNGPISASLVDSVAQTVDRTRRLIRQDDAEVAL
ISFQIEGECLLQQRDRQVRLRPGDFTIYDSTSPYDLQFEEDFCQLVLHMPRDLLRRRLGPVRQICAQRFGSDTGANSFAG
AYLKQIALQLTSLETATAEHHIKTALDLVGYAVEQNVQPCGHDVRRQSAAIREQVAQVISKHFRDDQLSTPSLARAVGIS
SRRLQEVCAEVGTTPMNAIWDIRLEKASDMLRSPAFAHLSITDICFACGFGDSSQFSRRYKTMYGVTPREDRKSGYRNGF
SGSVQTLSKSAGRFQRR

Sequences:

>Translated_337_residues
MAQIFELSREKPVRRVEAWQDIVSRTFVTLACDLPDKTDVTGSIASIGNGPISASLVDSVAQTVDRTRRLIRQDDAEVAL
ISFQIEGECLLQQRDRQVRLRPGDFTIYDSTSPYDLQFEEDFCQLVLHMPRDLLRRRLGPVRQICAQRFGSDTGANSFAG
AYLKQIALQLTSLETATAEHHIKTALDLVGYAVEQNVQPCGHDVRRQSAAIREQVAQVISKHFRDDQLSTPSLARAVGIS
SRRLQEVCAEVGTTPMNAIWDIRLEKASDMLRSPAFAHLSITDICFACGFGDSSQFSRRYKTMYGVTPREDRKSGYRNGF
SGSVQTLSKSAGRFQRR
>Mature_336_residues
AQIFELSREKPVRRVEAWQDIVSRTFVTLACDLPDKTDVTGSIASIGNGPISASLVDSVAQTVDRTRRLIRQDDAEVALI
SFQIEGECLLQQRDRQVRLRPGDFTIYDSTSPYDLQFEEDFCQLVLHMPRDLLRRRLGPVRQICAQRFGSDTGANSFAGA
YLKQIALQLTSLETATAEHHIKTALDLVGYAVEQNVQPCGHDVRRQSAAIREQVAQVISKHFRDDQLSTPSLARAVGISS
RRLQEVCAEVGTTPMNAIWDIRLEKASDMLRSPAFAHLSITDICFACGFGDSSQFSRRYKTMYGVTPREDRKSGYRNGFS
GSVQTLSKSAGRFQRR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=275, Percent_Identity=26.5454545454545, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37739; Mature: 37608

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQIFELSREKPVRRVEAWQDIVSRTFVTLACDLPDKTDVTGSIASIGNGPISASLVDSV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHH
AQTVDRTRRLIRQDDAEVALISFQIEGECLLQQRDRQVRLRPGDFTIYDSTSPYDLQFEE
HHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHCCCCEEEECCCCEEEECCCCCCCCEEHH
DFCQLVLHMPRDLLRRRLGPVRQICAQRFGSDTGANSFAGAYLKQIALQLTSLETATAEH
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HIKTALDLVGYAVEQNVQPCGHDVRRQSAAIREQVAQVISKHFRDDQLSTPSLARAVGIS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
SRRLQEVCAEVGTTPMNAIWDIRLEKASDMLRSPAFAHLSITDICFACGFGDSSQFSRRY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHH
KTMYGVTPREDRKSGYRNGFSGSVQTLSKSAGRFQRR
HHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQIFELSREKPVRRVEAWQDIVSRTFVTLACDLPDKTDVTGSIASIGNGPISASLVDSV
CHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHH
AQTVDRTRRLIRQDDAEVALISFQIEGECLLQQRDRQVRLRPGDFTIYDSTSPYDLQFEE
HHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHCCCCEEEECCCCEEEECCCCCCCCEEHH
DFCQLVLHMPRDLLRRRLGPVRQICAQRFGSDTGANSFAGAYLKQIALQLTSLETATAEH
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HIKTALDLVGYAVEQNVQPCGHDVRRQSAAIREQVAQVISKHFRDDQLSTPSLARAVGIS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
SRRLQEVCAEVGTTPMNAIWDIRLEKASDMLRSPAFAHLSITDICFACGFGDSSQFSRRY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHH
KTMYGVTPREDRKSGYRNGFSGSVQTLSKSAGRFQRR
HHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]