Click here to switch to the map view.

The map label for this gene is dltE [H]

Identifier: 89056039

GI number: 89056039

Start: 3611201

End: 3612037

Strand: Direct

Name: dltE [H]

Synonym: Jann_3548

Alternate gene names: 89056039

Gene position: 3611201-3612037 (Clockwise)

Preceding gene: 89056038

Following gene: 89056042

Centisome position: 83.63

GC content: 56.51

Gene sequence:

>837_bases
ATGGCTCAAATGATTGGAGCGGACCACAGGCGTTGGGCTTCGCTGCGACCCACCTTCCCCAACCCGGGCCGATACCGCGC
GGCCAACGCAAACATGAGACGGACGGACATGAAGACGACGGATCAGACCATTCTTGTTACCGGCGCAAGTTCCGGGATCG
GCGCAGTTTTGAGCACCAGTTTGGCTGCGGCGGGAAACCGCGTGATTGCCTGCGGTCGGCGCGAAGAACCATTACACGAT
CTTTCGGCGAAAAATGATGGCATCGGCTATCGGCTGTGCGACCTGCAGGACAATGATGCGATCAGAGAACTTGCTGCGGA
GCTTGGACCCCAGATCGATATCCTGATCAACTGCGCAGGCATTTCTCAAGAGCTGTCGCTGACGGATCAGGGGGGTCTGG
ATGCCCAGTTGAAGGAAGTGGACATCAATTTAAACGGCGTCATTCGGATGGTTCACGCGTTCCAACCGCATCTCACGGAC
AGAGGGGAGACTGCCATCGTGAACGTATCATCTGCGCTCGCCTTTGTTCCGGATGCAGCGCGTCCCATCTACAGCGCGAC
GAAGGCCGGTCTGCACGCCTATACGCGCGCGCTCCGGCATCAACTTGCTGGAACCGATGTGCGCGTGTTTGAACTGATGC
CTCCGCTTACAGACACCCCCATGGCCGAAAATGTTACCGACGTGCCGAAACTCTCGCCCGAGAAACTCGCGGAGATTTTC
ATCAGAGATTTGCAACGAAACACGCTTGAAATCGCACCTGGGCTTAGCTCCACAGTGAGATTGCTGTCCCGTCTCGCACC
GGCCTTTTTGTTTCGAAAGCTCAACTATCACAGATAA

Upstream 100 bases:

>100_bases
CTGATCCGTCGATCACGATCCTCCTCGGCAAGGCAGAACGCAACCGTCGTTTGCCAAGAGGTTAAACGCCAACGCCTGCT
GAACTCGCATCAGGCGCATC

Downstream 100 bases:

>100_bases
ATTGTGCCGCCTCCAACCGGCCGAGATTCTCCTGACGTCGCTGCATTTTCGCATGAATCTGATGAGGGGGACTTATCGAT
TCAAAACCGATGGATCGCAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MAQMIGADHRRWASLRPTFPNPGRYRAANANMRRTDMKTTDQTILVTGASSGIGAVLSTSLAAAGNRVIACGRREEPLHD
LSAKNDGIGYRLCDLQDNDAIRELAAELGPQIDILINCAGISQELSLTDQGGLDAQLKEVDINLNGVIRMVHAFQPHLTD
RGETAIVNVSSALAFVPDAARPIYSATKAGLHAYTRALRHQLAGTDVRVFELMPPLTDTPMAENVTDVPKLSPEKLAEIF
IRDLQRNTLEIAPGLSSTVRLLSRLAPAFLFRKLNYHR

Sequences:

>Translated_278_residues
MAQMIGADHRRWASLRPTFPNPGRYRAANANMRRTDMKTTDQTILVTGASSGIGAVLSTSLAAAGNRVIACGRREEPLHD
LSAKNDGIGYRLCDLQDNDAIRELAAELGPQIDILINCAGISQELSLTDQGGLDAQLKEVDINLNGVIRMVHAFQPHLTD
RGETAIVNVSSALAFVPDAARPIYSATKAGLHAYTRALRHQLAGTDVRVFELMPPLTDTPMAENVTDVPKLSPEKLAEIF
IRDLQRNTLEIAPGLSSTVRLLSRLAPAFLFRKLNYHR
>Mature_277_residues
AQMIGADHRRWASLRPTFPNPGRYRAANANMRRTDMKTTDQTILVTGASSGIGAVLSTSLAAAGNRVIACGRREEPLHDL
SAKNDGIGYRLCDLQDNDAIRELAAELGPQIDILINCAGISQELSLTDQGGLDAQLKEVDINLNGVIRMVHAFQPHLTDR
GETAIVNVSSALAFVPDAARPIYSATKAGLHAYTRALRHQLAGTDVRVFELMPPLTDTPMAENVTDVPKLSPEKLAEIFI
RDLQRNTLEIAPGLSSTVRLLSRLAPAFLFRKLNYHR

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=183, Percent_Identity=31.6939890710383, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4557649, Length=214, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=215, Percent_Identity=29.3023255813954, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI32483357, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI7705925, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=233, Percent_Identity=30.0429184549356, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082100, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787335, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=213, Percent_Identity=31.4553990610329, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=186, Percent_Identity=28.494623655914, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=234, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=214, Percent_Identity=33.1775700934579, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=248, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=202, Percent_Identity=34.1584158415842, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=208, Percent_Identity=32.2115384615385, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=216, Percent_Identity=30.0925925925926, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=196, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=173, Percent_Identity=32.3699421965318, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=199, Percent_Identity=35.678391959799, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=34.010152284264, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21358495, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30342; Mature: 30211

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMIGADHRRWASLRPTFPNPGRYRAANANMRRTDMKTTDQTILVTGASSGIGAVLSTS
CCCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHH
LAAAGNRVIACGRREEPLHDLSAKNDGIGYRLCDLQDNDAIRELAAELGPQIDILINCAG
HHHCCCEEEEECCCCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEECC
ISQELSLTDQGGLDAQLKEVDINLNGVIRMVHAFQPHLTDRGETAIVNVSSALAFVPDAA
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCCC
RPIYSATKAGLHAYTRALRHQLAGTDVRVFELMPPLTDTPMAENVTDVPKLSPEKLAEIF
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHH
IRDLQRNTLEIAPGLSSTVRLLSRLAPAFLFRKLNYHR
HHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQMIGADHRRWASLRPTFPNPGRYRAANANMRRTDMKTTDQTILVTGASSGIGAVLSTS
CCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHH
LAAAGNRVIACGRREEPLHDLSAKNDGIGYRLCDLQDNDAIRELAAELGPQIDILINCAG
HHHCCCEEEEECCCCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEECC
ISQELSLTDQGGLDAQLKEVDINLNGVIRMVHAFQPHLTDRGETAIVNVSSALAFVPDAA
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCCC
RPIYSATKAGLHAYTRALRHQLAGTDVRVFELMPPLTDTPMAENVTDVPKLSPEKLAEIF
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHH
IRDLQRNTLEIAPGLSSTVRLLSRLAPAFLFRKLNYHR
HHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]