Click here to switch to the map view.

The map label for this gene is rnz [H]

Identifier: 89056004

GI number: 89056004

Start: 3569251

End: 3570117

Strand: Direct

Name: rnz [H]

Synonym: Jann_3513

Alternate gene names: 89056004

Gene position: 3569251-3570117 (Clockwise)

Preceding gene: 89056003

Following gene: 89056006

Centisome position: 82.66

GC content: 62.28

Gene sequence:

>867_bases
GTGAGCAACGAGCTCCGTGATTACGTCGTGCTTTTGGGCACCAAGGGCGGGCCTTCACAGCGCCCCGGCTCCTCCAAGCC
AACATCCAACCTTTATGTGTTGAACGGCCAACCGATTGTCGTGGATTGCGGGATGGGCGTGACGCACGCGCTGATCGGCC
AAGGCATGCAGCTGCGCGATCTGTCGCTGATCTTCATCACGCATCTGCATGCGGACCACTATCTGGAGCTTGGGCCGCTG
ATCCACACCGCCTGGACGTCGGGTCTGAAGGAGCCGGTGGACATCTACGGGCCCGCCGCCCTGTCGTGCTATTGGGCCAA
TTTTGTCGAGGCCATGCGCGCCGACATCGACCTGCGCATTGCCGACGATGGCCGTATGGACATCCGTGATCTGGTCCGCA
TCCATCCGGTGGACCCGGGCAACGTTATGACGCGCGGTGGCCTGACAGTGGAGGTCATGCGCTCCCACCATCCGCCAATG
ACCGACTGCTTCGCGTATTCGTTTCGCACGGCCCGGACCCATGTTGTCTGCTCGGGCGATACCGCGCCCCTGCCCGCCCT
AGCGGACTTCGCACGCGGAGCGGATCTGCTGATCCATGAGGCGATGCTGGTGGAGGCTCTGCCGGACCTGATGCGGAAGA
TCGGTGACACATCAGGCAAGCTGAAGGCGCGGCTTTTGCGGGTCCATTCGCCTGCTCAAGATGTGGCGGCGATTGCGGCG
GAGGCGCATGTGAAGGCGCTGGCCCTCACGCACCTTATCCCATCCAATGATCCGAACTTCCCTGAGGCCGCGTGGCGCAC
AGCTGTGGAGGGCATTTATGAGGGGCCGTTGTTTGTGGGCCATGATGGTTTACGGATCGACCTTTGA

Upstream 100 bases:

>100_bases
GCGTCTCTGGCCCCAACCTGATCCTGTCACCGCCGCTGATCCTGACGGAAGACGACGCCGCAACCATCCTGAGCGCGCTC
GACAAGGGCTTCGCATCCCT

Downstream 100 bases:

>100_bases
GGCCGCCGGTGAAACGGCGTCGATGAGGGCCGCATCAGGGTTTGGGACGTTCAGGTAAGCCGCTTTGGGGATCCGGATCA
GACCCTGCAACCCAAGCACC

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSNELRDYVVLLGTKGGPSQRPGSSKPTSNLYVLNGQPIVVDCGMGVTHALIGQGMQLRDLSLIFITHLHADHYLELGPL
IHTAWTSGLKEPVDIYGPAALSCYWANFVEAMRADIDLRIADDGRMDIRDLVRIHPVDPGNVMTRGGLTVEVMRSHHPPM
TDCFAYSFRTARTHVVCSGDTAPLPALADFARGADLLIHEAMLVEALPDLMRKIGDTSGKLKARLLRVHSPAQDVAAIAA
EAHVKALALTHLIPSNDPNFPEAAWRTAVEGIYEGPLFVGHDGLRIDL

Sequences:

>Translated_288_residues
MSNELRDYVVLLGTKGGPSQRPGSSKPTSNLYVLNGQPIVVDCGMGVTHALIGQGMQLRDLSLIFITHLHADHYLELGPL
IHTAWTSGLKEPVDIYGPAALSCYWANFVEAMRADIDLRIADDGRMDIRDLVRIHPVDPGNVMTRGGLTVEVMRSHHPPM
TDCFAYSFRTARTHVVCSGDTAPLPALADFARGADLLIHEAMLVEALPDLMRKIGDTSGKLKARLLRVHSPAQDVAAIAA
EAHVKALALTHLIPSNDPNFPEAAWRTAVEGIYEGPLFVGHDGLRIDL
>Mature_287_residues
SNELRDYVVLLGTKGGPSQRPGSSKPTSNLYVLNGQPIVVDCGMGVTHALIGQGMQLRDLSLIFITHLHADHYLELGPLI
HTAWTSGLKEPVDIYGPAALSCYWANFVEAMRADIDLRIADDGRMDIRDLVRIHPVDPGNVMTRGGLTVEVMRSHHPPMT
DCFAYSFRTARTHVVCSGDTAPLPALADFARGADLLIHEAMLVEALPDLMRKIGDTSGKLKARLLRVHSPAQDVAAIAAE
AHVKALALTHLIPSNDPNFPEAAWRTAVEGIYEGPLFVGHDGLRIDL

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 31316; Mature: 31185

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNELRDYVVLLGTKGGPSQRPGSSKPTSNLYVLNGQPIVVDCGMGVTHALIGQGMQLRD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCHHHHHHCCCCEEEC
LSLIFITHLHADHYLELGPLIHTAWTSGLKEPVDIYGPAALSCYWANFVEAMRADIDLRI
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCEEEE
ADDGRMDIRDLVRIHPVDPGNVMTRGGLTVEVMRSHHPPMTDCFAYSFRTARTHVVCSGD
CCCCCCCHHHHHEECCCCCCCEEECCCCEEEEHHCCCCCHHHHHHHHHCCCCEEEEECCC
TAPLPALADFARGADLLIHEAMLVEALPDLMRKIGDTSGKLKARLLRVHSPAQDVAAIAA
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
EAHVKALALTHLIPSNDPNFPEAAWRTAVEGIYEGPLFVGHDGLRIDL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEC
>Mature Secondary Structure 
SNELRDYVVLLGTKGGPSQRPGSSKPTSNLYVLNGQPIVVDCGMGVTHALIGQGMQLRD
CCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCHHHHHHCCCCEEEC
LSLIFITHLHADHYLELGPLIHTAWTSGLKEPVDIYGPAALSCYWANFVEAMRADIDLRI
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCCEEEE
ADDGRMDIRDLVRIHPVDPGNVMTRGGLTVEVMRSHHPPMTDCFAYSFRTARTHVVCSGD
CCCCCCCHHHHHEECCCCCCCEEECCCCEEEEHHCCCCCHHHHHHHHHCCCCEEEEECCC
TAPLPALADFARGADLLIHEAMLVEALPDLMRKIGDTSGKLKARLLRVHSPAQDVAAIAA
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
EAHVKALALTHLIPSNDPNFPEAAWRTAVEGIYEGPLFVGHDGLRIDL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]