Click here to switch to the map view.

The map label for this gene is betC [H]

Identifier: 89055756

GI number: 89055756

Start: 3318222

End: 3320534

Strand: Direct

Name: betC [H]

Synonym: Jann_3265

Alternate gene names: 89055756

Gene position: 3318222-3320534 (Clockwise)

Preceding gene: 89055754

Following gene: 89055757

Centisome position: 76.85

GC content: 62.47

Gene sequence:

>2313_bases
ATGAGCTTTACGAAAGACAGCGTCGCGGGTGGCAACATCTGCGTGATCTGGGTCGATGACATGATCGACGTGTTCACCTG
GCGCAAGACCTTCGGGCTGGAAATCCAGACCCCCCATCTGGATCGTCTGATGTCCGAGGGCGTGCGGTTTTCCAACGCCT
ATGCCACCGTGCCGCTCTGCGCGCCCTGCCGTGCGGAACTGGCGACCGGGATCTCTCCGTTTCGCAGCGGCCTGGTGGAC
CTCAACCGCTTCTGGCGGGACGTCTATCCGCCAGAGAAAGCGTGGGCCTACGACCTGCGCCGCAACGGGTTCTACAACTT
TACCACCGGCAAAGTAGACAGCAATTACAAACCGATGCCGGAAGAGTACCGCCGCCTGCTGTTCCATGAGGACGTATTGG
CCGAAGACAAGGGCCGCCGCCGAGGCGTCCATGCCTACCTGGATCGCGGTCCCGGCATCAAAGGCGTGAACCACCCCGAC
GATGACGGCAGCTATGATCACACGTTCTTCGACAACCGCGTGGCGCAGAATGCCATTGATTTCCTGGGCCGCGCGGATCC
AAACCGTCGCCACCTGATCCAGCTTGGGTTCAAACATCCGCACTACAACCTCGTCGCGCCCGACCGCTTCTATGCGCAGT
ATGACCCGGCTGACATTGTCTGGCCCTCCATCGCAGCGCCCGAGGATTACTTCGGCCCCCAACCCGGATTTGCCGTTTAT
GAAGCCGCCTATATCGCCAATGGCGCCTGGACGCCCGAGAAGGCGGGCGACAATGCCTGGCGTCAGGTTGTGCGCGCCTA
TTTCGCCTGTATCAGCCACGTGGATCACGAAATCGGGCGCTTCATGGACGCCTTGCGCACCTCGCCTTTCGCCGAAAATA
CGACGGTGATTTTCCTCAGCGACAACGGCTTCAACCTTGGCAACCACGACAGTTTTCACAAGATGAGCCAGTGGGATAGC
GCCGCCCACATCCCCCTTGGCCTCTGGCACGCGGGGCTTGAGCCGCGCGTGGAACCCATCCCCGTCTCACTCCACAATAT
CCCCAAGACGATCATGGATCTGGCAGGCCTACCGCCCCGGCCCGACTGGACCTCCGGCCAGTCCCTGCTGCCCTTGATCG
ACGACAGTTTCGGTAGCTACGACACCACGAAATCCCCCATAACCTGCGTGTTCGGCACCCTCTCCGTTCGCCCCTCCGTC
GATGGCCTCAGCCAGTATCGCTATTTCCGCTACCCCAACGGCGAAGAGCATGTCTACGATCTGGTAGAAGACCCCGGAGA
GACCCAAAACCTTGCCGACAGCGCCCCGCTGGAAGCCCTGCGGGACGAGTTGACCCGGGGGGCCCTGAACCTTGGCCTTG
ACCTGCGCGGGTTTGAGAACCCGGCAGAGGGCGTGAACGCGATGATGGCCGTGGACGGCTCCGTCGTGTTGGCCGGAGGG
CGCGCGGACAACGATTATTGGGCCTACGGCAAGGACGCCGAAAAGATCAAAGAAGAGAAAGACGGCGGCACCGATACGCT
TTGGTACATGGCGGGGCCCGATGATTACGTCCTCCACTGCCCCGCCAACATCGAGAAAATCCGCATCGCCACCGTCGTGT
CCCGCAAGGAGGAGGGTGCAGGCCAAGGCCCCCAACCCGAGGGCAAACGCATCCGCATCGTGGCCCACCCCGACAGCCCC
ATCGAATTCGAGACGTCCGAACGGGTCGAAGTCGACGTCACAGGTTCCACCGGGGACGATGTGATGATCGGCCCCAAACA
CGGCTCCGCCACCTTCTATGGCGGCAAAGGCAATGACACGATGATCGCGCGTGCCAAGCAGGGCAACCGCCGCCATGGCT
TCTATGGCGAGGAGGGCAACGATACGCTCCATGGTGGGCCGGGTCGCGATACGCTGGACGGTGGCACCGGTGACGACGAG
ATCCACGGCAACACGGGCCGCAATCACATCTTCGGCGGCCACGGCAACGATGTCATCTACGATGGTGAAGGGGCCTCCAC
AATCGACACAGGGCCCGGCCAGAACACGCTACATCTGTGCGCCGGAGATCACGAGGTCGCCACCGGCTCCGGCGTCACCC
GCATAACGCCCGAACCCGGGGCGAAAGTCTTCACACCCGCTTATGGTGGCGTGACCGTGATCACGCAATGGGACGCGGAT
CAGACCTACGATCTCAGCGCCTGGCCCGCCCCGCCGACGATCACGCGGTCCGTCAACCGTGTCCGCATGCGCTGCGGCCT
CACTATCCTTGATCTCCACGATGTGGCCGCGATCGCCGACATCACAGCGCAACTCGTCGGACCCAAGCGCTGA

Upstream 100 bases:

>100_bases
ACGTCTGGCTGTTTCCGGGCCGGGCATTACTGCACGAAGACACCGAGCAAGAGGCAAAGGCACTGACCGCGCTGAACCGC
CATCACCTCTGGGCTGCTGC

Downstream 100 bases:

>100_bases
CGCCCCCCTTTCATCTTGCCACCAAAACGCAATCGCGCACGGTCCCGCAAACACCACCGACGCCGGTCACAGACCCTACG
GGACGGCGGGAGGGGCGAGG

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MSFTKDSVAGGNICVIWVDDMIDVFTWRKTFGLEIQTPHLDRLMSEGVRFSNAYATVPLCAPCRAELATGISPFRSGLVD
LNRFWRDVYPPEKAWAYDLRRNGFYNFTTGKVDSNYKPMPEEYRRLLFHEDVLAEDKGRRRGVHAYLDRGPGIKGVNHPD
DDGSYDHTFFDNRVAQNAIDFLGRADPNRRHLIQLGFKHPHYNLVAPDRFYAQYDPADIVWPSIAAPEDYFGPQPGFAVY
EAAYIANGAWTPEKAGDNAWRQVVRAYFACISHVDHEIGRFMDALRTSPFAENTTVIFLSDNGFNLGNHDSFHKMSQWDS
AAHIPLGLWHAGLEPRVEPIPVSLHNIPKTIMDLAGLPPRPDWTSGQSLLPLIDDSFGSYDTTKSPITCVFGTLSVRPSV
DGLSQYRYFRYPNGEEHVYDLVEDPGETQNLADSAPLEALRDELTRGALNLGLDLRGFENPAEGVNAMMAVDGSVVLAGG
RADNDYWAYGKDAEKIKEEKDGGTDTLWYMAGPDDYVLHCPANIEKIRIATVVSRKEEGAGQGPQPEGKRIRIVAHPDSP
IEFETSERVEVDVTGSTGDDVMIGPKHGSATFYGGKGNDTMIARAKQGNRRHGFYGEEGNDTLHGGPGRDTLDGGTGDDE
IHGNTGRNHIFGGHGNDVIYDGEGASTIDTGPGQNTLHLCAGDHEVATGSGVTRITPEPGAKVFTPAYGGVTVITQWDAD
QTYDLSAWPAPPTITRSVNRVRMRCGLTILDLHDVAAIADITAQLVGPKR

Sequences:

>Translated_770_residues
MSFTKDSVAGGNICVIWVDDMIDVFTWRKTFGLEIQTPHLDRLMSEGVRFSNAYATVPLCAPCRAELATGISPFRSGLVD
LNRFWRDVYPPEKAWAYDLRRNGFYNFTTGKVDSNYKPMPEEYRRLLFHEDVLAEDKGRRRGVHAYLDRGPGIKGVNHPD
DDGSYDHTFFDNRVAQNAIDFLGRADPNRRHLIQLGFKHPHYNLVAPDRFYAQYDPADIVWPSIAAPEDYFGPQPGFAVY
EAAYIANGAWTPEKAGDNAWRQVVRAYFACISHVDHEIGRFMDALRTSPFAENTTVIFLSDNGFNLGNHDSFHKMSQWDS
AAHIPLGLWHAGLEPRVEPIPVSLHNIPKTIMDLAGLPPRPDWTSGQSLLPLIDDSFGSYDTTKSPITCVFGTLSVRPSV
DGLSQYRYFRYPNGEEHVYDLVEDPGETQNLADSAPLEALRDELTRGALNLGLDLRGFENPAEGVNAMMAVDGSVVLAGG
RADNDYWAYGKDAEKIKEEKDGGTDTLWYMAGPDDYVLHCPANIEKIRIATVVSRKEEGAGQGPQPEGKRIRIVAHPDSP
IEFETSERVEVDVTGSTGDDVMIGPKHGSATFYGGKGNDTMIARAKQGNRRHGFYGEEGNDTLHGGPGRDTLDGGTGDDE
IHGNTGRNHIFGGHGNDVIYDGEGASTIDTGPGQNTLHLCAGDHEVATGSGVTRITPEPGAKVFTPAYGGVTVITQWDAD
QTYDLSAWPAPPTITRSVNRVRMRCGLTILDLHDVAAIADITAQLVGPKR
>Mature_769_residues
SFTKDSVAGGNICVIWVDDMIDVFTWRKTFGLEIQTPHLDRLMSEGVRFSNAYATVPLCAPCRAELATGISPFRSGLVDL
NRFWRDVYPPEKAWAYDLRRNGFYNFTTGKVDSNYKPMPEEYRRLLFHEDVLAEDKGRRRGVHAYLDRGPGIKGVNHPDD
DGSYDHTFFDNRVAQNAIDFLGRADPNRRHLIQLGFKHPHYNLVAPDRFYAQYDPADIVWPSIAAPEDYFGPQPGFAVYE
AAYIANGAWTPEKAGDNAWRQVVRAYFACISHVDHEIGRFMDALRTSPFAENTTVIFLSDNGFNLGNHDSFHKMSQWDSA
AHIPLGLWHAGLEPRVEPIPVSLHNIPKTIMDLAGLPPRPDWTSGQSLLPLIDDSFGSYDTTKSPITCVFGTLSVRPSVD
GLSQYRYFRYPNGEEHVYDLVEDPGETQNLADSAPLEALRDELTRGALNLGLDLRGFENPAEGVNAMMAVDGSVVLAGGR
ADNDYWAYGKDAEKIKEEKDGGTDTLWYMAGPDDYVLHCPANIEKIRIATVVSRKEEGAGQGPQPEGKRIRIVAHPDSPI
EFETSERVEVDVTGSTGDDVMIGPKHGSATFYGGKGNDTMIARAKQGNRRHGFYGEEGNDTLHGGPGRDTLDGGTGDDEI
HGNTGRNHIFGGHGNDVIYDGEGASTIDTGPGQNTLHLCAGDHEVATGSGVTRITPEPGAKVFTPAYGGVTVITQWDADQ
TYDLSAWPAPPTITRSVNRVRMRCGLTILDLHDVAAIADITAQLVGPKR

Specific function: Converts choline-O-sulfate into choline [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI39930577, Length=436, Percent_Identity=25.4587155963303, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1790112, Length=457, Percent_Identity=25.164113785558, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR017785
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.6 [H]

Molecular weight: Translated: 84782; Mature: 84651

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTKDSVAGGNICVIWVDDMIDVFTWRKTFGLEIQTPHLDRLMSEGVRFSNAYATVPLC
CCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCEEECCHHHHHHHCCCEECCCEEECEEC
APCRAELATGISPFRSGLVDLNRFWRDVYPPEKAWAYDLRRNGFYNFTTGKVDSNYKPMP
CCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCC
EEYRRLLFHEDVLAEDKGRRRGVHAYLDRGPGIKGVNHPDDDGSYDHTFFDNRVAQNAID
HHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FLGRADPNRRHLIQLGFKHPHYNLVAPDRFYAQYDPADIVWPSIAAPEDYFGPQPGFAVY
HHHCCCCCCCEEEEEECCCCCCEEECCCHHEEECCCHHEECCCCCCCHHHCCCCCCHHHE
EAAYIANGAWTPEKAGDNAWRQVVRAYFACISHVDHEIGRFMDALRTSPFAENTTVIFLS
EHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
DNGFNLGNHDSFHKMSQWDSAAHIPLGLWHAGLEPRVEPIPVSLHNIPKTIMDLAGLPPR
CCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
PDWTSGQSLLPLIDDSFGSYDTTKSPITCVFGTLSVRPSVDGLSQYRYFRYPNGEEHVYD
CCCCCCCCCCCEECCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCEEEECCCCHHHHHH
LVEDPGETQNLADSAPLEALRDELTRGALNLGLDLRGFENPAEGVNAMMAVDGSVVLAGG
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCEEEEECCCEEEECC
RADNDYWAYGKDAEKIKEEKDGGTDTLWYMAGPDDYVLHCPANIEKIRIATVVSRKEEGA
CCCCCCEECCCCHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCEEEEEEEHHHHHCCC
GQGPQPEGKRIRIVAHPDSPIEFETSERVEVDVTGSTGDDVMIGPKHGSATFYGGKGNDT
CCCCCCCCCEEEEEECCCCCCEECCCCEEEEEEECCCCCCEEECCCCCCEEEECCCCCCE
MIARAKQGNRRHGFYGEEGNDTLHGGPGRDTLDGGTGDDEIHGNTGRNHIFGGHGNDVIY
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEE
DGEGASTIDTGPGQNTLHLCAGDHEVATGSGVTRITPEPGAKVFTPAYGGVTVITQWDAD
CCCCCCCCCCCCCCCEEEEEECCCEEECCCCEEEECCCCCCEEEEECCCCEEEEEECCCC
QTYDLSAWPAPPTITRSVNRVRMRCGLTILDLHDVAAIADITAQLVGPKR
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFTKDSVAGGNICVIWVDDMIDVFTWRKTFGLEIQTPHLDRLMSEGVRFSNAYATVPLC
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCEEECCHHHHHHHCCCEECCCEEECEEC
APCRAELATGISPFRSGLVDLNRFWRDVYPPEKAWAYDLRRNGFYNFTTGKVDSNYKPMP
CCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCC
EEYRRLLFHEDVLAEDKGRRRGVHAYLDRGPGIKGVNHPDDDGSYDHTFFDNRVAQNAID
HHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FLGRADPNRRHLIQLGFKHPHYNLVAPDRFYAQYDPADIVWPSIAAPEDYFGPQPGFAVY
HHHCCCCCCCEEEEEECCCCCCEEECCCHHEEECCCHHEECCCCCCCHHHCCCCCCHHHE
EAAYIANGAWTPEKAGDNAWRQVVRAYFACISHVDHEIGRFMDALRTSPFAENTTVIFLS
EHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
DNGFNLGNHDSFHKMSQWDSAAHIPLGLWHAGLEPRVEPIPVSLHNIPKTIMDLAGLPPR
CCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
PDWTSGQSLLPLIDDSFGSYDTTKSPITCVFGTLSVRPSVDGLSQYRYFRYPNGEEHVYD
CCCCCCCCCCCEECCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCEEEECCCCHHHHHH
LVEDPGETQNLADSAPLEALRDELTRGALNLGLDLRGFENPAEGVNAMMAVDGSVVLAGG
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCEEEEECCCEEEECC
RADNDYWAYGKDAEKIKEEKDGGTDTLWYMAGPDDYVLHCPANIEKIRIATVVSRKEEGA
CCCCCCEECCCCHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCEEEEEEEHHHHHCCC
GQGPQPEGKRIRIVAHPDSPIEFETSERVEVDVTGSTGDDVMIGPKHGSATFYGGKGNDT
CCCCCCCCCEEEEEECCCCCCEECCCCEEEEEEECCCCCCEEECCCCCCEEEECCCCCCE
MIARAKQGNRRHGFYGEEGNDTLHGGPGRDTLDGGTGDDEIHGNTGRNHIFGGHGNDVIY
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEE
DGEGASTIDTGPGQNTLHLCAGDHEVATGSGVTRITPEPGAKVFTPAYGGVTVITQWDAD
CCCCCCCCCCCCCCCEEEEEECCCEEECCCCEEEECCCCCCEEEEECCCCEEEEEECCCC
QTYDLSAWPAPPTITRSVNRVRMRCGLTILDLHDVAAIADITAQLVGPKR
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141699; 11481430; 9736747 [H]