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The map label for this gene is efp

Identifier: 89055745

GI number: 89055745

Start: 3304481

End: 3305044

Strand: Direct

Name: efp

Synonym: Jann_3254

Alternate gene names: 89055745

Gene position: 3304481-3305044 (Clockwise)

Preceding gene: 89055742

Following gene: 89055750

Centisome position: 76.53

GC content: 56.56

Gene sequence:

>564_bases
ATGCCGAAAATTAACGGAAACGAGATCAGGCCGGGCAATGTCCTGGAGCATAATGGCGGGCTTTGGGCTGCCGTCAAAGT
GGATCATGTGAAACCCGGCAAAGGCGGCGCATTTGCGCAGGTCGAGCTGCGCAATCTTCGTAACGGGTCAAAGCTGAACG
AACGGTTCAGGTCCGCAGACAAAGTGGAGCGTGTTCGACTGGAACAGAAGGACCAGCAATTCCTGTACGAGAGTGACGGG
ATGCTGGTGTTCATGGATGCCGAAACCTATGAGCAGATCGAACTGCCCGCTGAACTGCTGGGTGAGCGGCGTCCTTTCCT
GCAGGACGGCATGACCATCGTGGTGGAATTCCATGACGATGAGGCGCTGAACGCGTCGCTGCCCCAGAAGGTCGTATGCA
AAGTCGTGGAGACGGAACCTGTCGTGAAGGGCCAGACGGCGGCCAATTCCTTCAAGCCCGCGATCCTCGACAACGGTGTG
AAGGTCATGGTGCCTCCATTCGTGGGTCAGGATGAGGACATTGTCGTCAATACGGAAACGATGGATTATTCCGAGCGCGC
CTGA

Upstream 100 bases:

>100_bases
CGCCCTTTTTGTGCACAGGTTCCGGTGTATGGACACCCCTCCAGAGCCCAGATATAGGATGCGTCAACGATTTCTCAAGG
TTTTGCCAAGGTTTTGCCCC

Downstream 100 bases:

>100_bases
ATCGCGCCCTGCCCCGCCAATCGTCTGACCCTACCGCTTGCCGGACCACGGACCGGGCCTGACCCGACGGTCCCCCGCAC
GCGGGACGCGCCCGATATCC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPKINGNEIRPGNVLEHNGGLWAAVKVDHVKPGKGGAFAQVELRNLRNGSKLNERFRSADKVERVRLEQKDQQFLYESDG
MLVFMDAETYEQIELPAELLGERRPFLQDGMTIVVEFHDDEALNASLPQKVVCKVVETEPVVKGQTAANSFKPAILDNGV
KVMVPPFVGQDEDIVVNTETMDYSERA

Sequences:

>Translated_187_residues
MPKINGNEIRPGNVLEHNGGLWAAVKVDHVKPGKGGAFAQVELRNLRNGSKLNERFRSADKVERVRLEQKDQQFLYESDG
MLVFMDAETYEQIELPAELLGERRPFLQDGMTIVVEFHDDEALNASLPQKVVCKVVETEPVVKGQTAANSFKPAILDNGV
KVMVPPFVGQDEDIVVNTETMDYSERA
>Mature_186_residues
PKINGNEIRPGNVLEHNGGLWAAVKVDHVKPGKGGAFAQVELRNLRNGSKLNERFRSADKVERVRLEQKDQQFLYESDGM
LVFMDAETYEQIELPAELLGERRPFLQDGMTIVVEFHDDEALNASLPQKVVCKVVETEPVVKGQTAANSFKPAILDNGVK
VMVPPFVGQDEDIVVNTETMDYSERA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=186, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87082061, Length=191, Percent_Identity=33.5078534031414, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_JANSC (Q28M91)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_511196.1
- ProteinModelPortal:   Q28M91
- SMR:   Q28M91
- STRING:   Q28M91
- GeneID:   3935726
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_3254
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q28M91
- ProtClustDB:   PRK00529
- BioCyc:   JSP290400:JANN_3254-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20896; Mature: 20765

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKINGNEIRPGNVLEHNGGLWAAVKVDHVKPGKGGAFAQVELRNLRNGSKLNERFRSAD
CCCCCCCEECCCCEEEECCCEEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
KVERVRLEQKDQQFLYESDGMLVFMDAETYEQIELPAELLGERRPFLQDGMTIVVEFHDD
HHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHCCCHHHHCCCCCCCCCCCEEEEEECCC
EALNASLPQKVVCKVVETEPVVKGQTAANSFKPAILDNGVKVMVPPFVGQDEDIVVNTET
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCCCCEEEEECC
MDYSERA
CCCCCCC
>Mature Secondary Structure 
PKINGNEIRPGNVLEHNGGLWAAVKVDHVKPGKGGAFAQVELRNLRNGSKLNERFRSAD
CCCCCCEECCCCEEEECCCEEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
KVERVRLEQKDQQFLYESDGMLVFMDAETYEQIELPAELLGERRPFLQDGMTIVVEFHDD
HHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHCCCHHHHCCCCCCCCCCCEEEEEECCC
EALNASLPQKVVCKVVETEPVVKGQTAANSFKPAILDNGVKVMVPPFVGQDEDIVVNTET
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCCCCEEEEECC
MDYSERA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA