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The map label for this gene is yciR [C]

Identifier: 89055710

GI number: 89055710

Start: 3264319

End: 3265983

Strand: Direct

Name: yciR [C]

Synonym: Jann_3219

Alternate gene names: 89055710

Gene position: 3264319-3265983 (Clockwise)

Preceding gene: 89055709

Following gene: 89055711

Centisome position: 75.6

GC content: 51.95

Gene sequence:

>1665_bases
ATGGACCAAGGTGCCCACCTCCTCACCATCGACAAGTTGATGCGCTGGGAACACTTTTCAGTCAAAGTTCGGCTCACCAA
AAAAACTGGTGAGCCTGTCTGGGTTACGATGACTTGGACGCCACTAACGGATCCAGAAAACGGCAATCGCTGGTGGCTAT
GCTCCTTGATCGAGCTTCAACCTCATCCAGCTCAAAGTAAGAACGTACTCGATTTTAGAAACCAGTCATCTGCCAACGAC
TTGGTGACGCAGTATACAGAACAAGTCGCGCATTTAGAGAGCGAGAATAGACGTCTGCGCTCCATCGCCAAGGCTGTCAC
ACGAGATTCCAACGAAGATCCGCTGACTGGCCTATCGAACCGGAGGCACTTCGAGGCAAACGTAAGCGTTTGGATTGCCG
CTTTGAGAAATCGGGGTGCCGCATTCGCGATACTTTTTATCGATTTGGATCGCTTCAAGACGATTAACGACACGCTTGGT
CATGAAGCGGGTGATGGTTTGCTTGTTGCCGTCGCATCCATGTTGAAACGGATTACCCATAGTTCGGATTTGGTCGCTCG
GTTGGGGGGGGACGAGTTTGTCATTCTAAGGCCTCTTGGCGAGAGCGCCCTCGAAATTAGCGGCTTAGCAGACGAAATCA
TACGTGAGATGTCCAAACCATTTGAATTTGACGGAAAATCGGTTTCGTGTGGTGCCAGCGTCGGGGTGGCAATTGCAGAC
AAGGACGCCAGGAACCCCGAAGAAGTCGTCGGAGATGCAGACACTGCGCTTTATCACGCCAAGTCGACTGGCCGTGCACG
TTGGTCTTTTTTTACAGCAGAGATGCGTGCTCAGTCCGTTGCGACCAGACATCTGGCGACAGAGCTGTTAGCTGCTTGCG
AACGGAAAGAGTTCGTTCCCTATTTCCAACCGCTGGTTGATGCGTCGACAGGTCGGATTACGGGTGTTGAAGTCCTTGTC
AGATGGTCACATCCGACGAGGGGCCTGGTGCCGCCAACAGATTTCTTAGATGTCGCAGCACAAATGGGAATCCTGGCTGA
GATTGACACGATCTTGTTTAGCCGCCTTCGCGAGGCGGTGGCATATCTTGATACAGCGCATATAGAGGTCCCCAGGTTTG
CGATCAACGTTTCTGCTGGTCGACTGTCCGATTCGGCACTCTTACATGATATCAACGTTTCAGGGATCGATCCGAAACGA
CTGACTGTTGAGATACTTGAGTCAGTGTACCTGGAGCGGATCCATGATGCCACGAGTTGGACATTAGAGGAACTGCGCGA
ACTCGGCGTCGAGGTTGCGGTAGATGATTTCGGAACCGGTCACGCTTCAGTCCAAGGACTTCTTCAGATCAAACCTGACG
TGCTAAAGATTGATCGTCAGTTCGTTCAACCTGCCGCAGAAAGTGAACGTGCCCGAGCGTTGGTGAAGTCCCTCATAGGC
ATTGGGAAAAGTCTCGGATTGAAAGTGGTCGCTGAAGGGGTGGAAAATGAGGCCCAGGCACAGCTCGCTCGCGACTTGGG
CTGTGACATTTTGCAGGGATTTTACTTTGGAAAGCCGATGGCGGAACCCGACCTATTCAAAGTGCTGAACGAAACGAACG
GTTGCCTTTGGCGCCCGACCTCGACAGTCCAACAATCAGAACTATCAATAAACATACTGCCCTAG

Upstream 100 bases:

>100_bases
GATGGTGTTCCATTGGTGCAATAAGCCGTTTTTTCAGGTTATGGGCCTCGATGAAGCAGACGTCATAGGTCAACGGGCAA
CGATCTTTGTGGGTCCAGAA

Downstream 100 bases:

>100_bases
TGCTGCTCGTTGTCGTCACCAACTAGTATTGGGGGCCTTGGGTCCGAGTTCGTTTTTTTTGACATAACACCTCAGTCTCC
GCCTAGGTGACCAAGTCCGT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MDQGAHLLTIDKLMRWEHFSVKVRLTKKTGEPVWVTMTWTPLTDPENGNRWWLCSLIELQPHPAQSKNVLDFRNQSSAND
LVTQYTEQVAHLESENRRLRSIAKAVTRDSNEDPLTGLSNRRHFEANVSVWIAALRNRGAAFAILFIDLDRFKTINDTLG
HEAGDGLLVAVASMLKRITHSSDLVARLGGDEFVILRPLGESALEISGLADEIIREMSKPFEFDGKSVSCGASVGVAIAD
KDARNPEEVVGDADTALYHAKSTGRARWSFFTAEMRAQSVATRHLATELLAACERKEFVPYFQPLVDASTGRITGVEVLV
RWSHPTRGLVPPTDFLDVAAQMGILAEIDTILFSRLREAVAYLDTAHIEVPRFAINVSAGRLSDSALLHDINVSGIDPKR
LTVEILESVYLERIHDATSWTLEELRELGVEVAVDDFGTGHASVQGLLQIKPDVLKIDRQFVQPAAESERARALVKSLIG
IGKSLGLKVVAEGVENEAQAQLARDLGCDILQGFYFGKPMAEPDLFKVLNETNGCLWRPTSTVQQSELSINILP

Sequences:

>Translated_554_residues
MDQGAHLLTIDKLMRWEHFSVKVRLTKKTGEPVWVTMTWTPLTDPENGNRWWLCSLIELQPHPAQSKNVLDFRNQSSAND
LVTQYTEQVAHLESENRRLRSIAKAVTRDSNEDPLTGLSNRRHFEANVSVWIAALRNRGAAFAILFIDLDRFKTINDTLG
HEAGDGLLVAVASMLKRITHSSDLVARLGGDEFVILRPLGESALEISGLADEIIREMSKPFEFDGKSVSCGASVGVAIAD
KDARNPEEVVGDADTALYHAKSTGRARWSFFTAEMRAQSVATRHLATELLAACERKEFVPYFQPLVDASTGRITGVEVLV
RWSHPTRGLVPPTDFLDVAAQMGILAEIDTILFSRLREAVAYLDTAHIEVPRFAINVSAGRLSDSALLHDINVSGIDPKR
LTVEILESVYLERIHDATSWTLEELRELGVEVAVDDFGTGHASVQGLLQIKPDVLKIDRQFVQPAAESERARALVKSLIG
IGKSLGLKVVAEGVENEAQAQLARDLGCDILQGFYFGKPMAEPDLFKVLNETNGCLWRPTSTVQQSELSINILP
>Mature_554_residues
MDQGAHLLTIDKLMRWEHFSVKVRLTKKTGEPVWVTMTWTPLTDPENGNRWWLCSLIELQPHPAQSKNVLDFRNQSSAND
LVTQYTEQVAHLESENRRLRSIAKAVTRDSNEDPLTGLSNRRHFEANVSVWIAALRNRGAAFAILFIDLDRFKTINDTLG
HEAGDGLLVAVASMLKRITHSSDLVARLGGDEFVILRPLGESALEISGLADEIIREMSKPFEFDGKSVSCGASVGVAIAD
KDARNPEEVVGDADTALYHAKSTGRARWSFFTAEMRAQSVATRHLATELLAACERKEFVPYFQPLVDASTGRITGVEVLV
RWSHPTRGLVPPTDFLDVAAQMGILAEIDTILFSRLREAVAYLDTAHIEVPRFAINVSAGRLSDSALLHDINVSGIDPKR
LTVEILESVYLERIHDATSWTLEELRELGVEVAVDDFGTGHASVQGLLQIKPDVLKIDRQFVQPAAESERARALVKSLIG
IGKSLGLKVVAEGVENEAQAQLARDLGCDILQGFYFGKPMAEPDLFKVLNETNGCLWRPTSTVQQSELSINILP

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=417, Percent_Identity=32.1342925659472, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87081921, Length=413, Percent_Identity=29.5399515738499, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=34.453781512605, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=31.4285714285714, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788502, Length=254, Percent_Identity=29.9212598425197, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI226510982, Length=394, Percent_Identity=26.6497461928934, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081980, Length=246, Percent_Identity=29.2682926829268, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787055, Length=256, Percent_Identity=32.03125, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788381, Length=181, Percent_Identity=37.0165745856354, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=28.099173553719, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=27.9166666666667, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788849, Length=259, Percent_Identity=32.046332046332, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=33.5164835164835, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082096, Length=218, Percent_Identity=28.8990825688073, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787262, Length=290, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=183, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI145693134, Length=181, Percent_Identity=35.3591160220994, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788956, Length=171, Percent_Identity=31.5789473684211, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=33.5195530726257, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=31.4465408805031, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=31.4917127071823, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=166, Percent_Identity=30.1204819277108, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787816, Length=202, Percent_Identity=31.1881188118812, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787056, Length=158, Percent_Identity=31.6455696202532, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=31.055900621118, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787410, Length=134, Percent_Identity=29.1044776119403, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 61245; Mature: 61245

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQGAHLLTIDKLMRWEHFSVKVRLTKKTGEPVWVTMTWTPLTDPENGNRWWLCSLIELQ
CCCCCEEEEHHHHHCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEC
PHPAQSKNVLDFRNQSSANDLVTQYTEQVAHLESENRRLRSIAKAVTRDSNEDPLTGLSN
CCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RRHFEANVSVWIAALRNRGAAFAILFIDLDRFKTINDTLGHEAGDGLLVAVASMLKRITH
CCEEECCHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
SSDLVARLGGDEFVILRPLGESALEISGLADEIIREMSKPFEFDGKSVSCGASVGVAIAD
CCHHHHHCCCCCEEEEECCCCCHHHHHCHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEC
KDARNPEEVVGDADTALYHAKSTGRARWSFFTAEMRAQSVATRHLATELLAACERKEFVP
CCCCCHHHHHCCCHHHEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
YFQPLVDASTGRITGVEVLVRWSHPTRGLVPPTDFLDVAAQMGILAEIDTILFSRLREAV
HHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLDTAHIEVPRFAINVSAGRLSDSALLHDINVSGIDPKRLTVEILESVYLERIHDATSW
HHHHHCCEECCEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHH
TLEELRELGVEVAVDDFGTGHASVQGLLQIKPDVLKIDRQFVQPAAESERARALVKSLIG
HHHHHHHCCCEEEEECCCCCCHHHHHHEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IGKSLGLKVVAEGVENEAQAQLARDLGCDILQGFYFGKPMAEPDLFKVLNETNGCLWRPT
CCHHCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECCC
STVQQSELSINILP
CCCCCCCCEEEECC
>Mature Secondary Structure
MDQGAHLLTIDKLMRWEHFSVKVRLTKKTGEPVWVTMTWTPLTDPENGNRWWLCSLIELQ
CCCCCEEEEHHHHHCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEC
PHPAQSKNVLDFRNQSSANDLVTQYTEQVAHLESENRRLRSIAKAVTRDSNEDPLTGLSN
CCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RRHFEANVSVWIAALRNRGAAFAILFIDLDRFKTINDTLGHEAGDGLLVAVASMLKRITH
CCEEECCHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
SSDLVARLGGDEFVILRPLGESALEISGLADEIIREMSKPFEFDGKSVSCGASVGVAIAD
CCHHHHHCCCCCEEEEECCCCCHHHHHCHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEC
KDARNPEEVVGDADTALYHAKSTGRARWSFFTAEMRAQSVATRHLATELLAACERKEFVP
CCCCCHHHHHCCCHHHEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
YFQPLVDASTGRITGVEVLVRWSHPTRGLVPPTDFLDVAAQMGILAEIDTILFSRLREAV
HHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLDTAHIEVPRFAINVSAGRLSDSALLHDINVSGIDPKRLTVEILESVYLERIHDATSW
HHHHHCCEECCEEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHH
TLEELRELGVEVAVDDFGTGHASVQGLLQIKPDVLKIDRQFVQPAAESERARALVKSLIG
HHHHHHHCCCEEEEECCCCCCHHHHHHEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IGKSLGLKVVAEGVENEAQAQLARDLGCDILQGFYFGKPMAEPDLFKVLNETNGCLWRPT
CCHHCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECCC
STVQQSELSINILP
CCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]