Click here to switch to the map view.

The map label for this gene is nanR [H]

Identifier: 89055558

GI number: 89055558

Start: 3100446

End: 3101222

Strand: Direct

Name: nanR [H]

Synonym: Jann_3067

Alternate gene names: 89055558

Gene position: 3100446-3101222 (Clockwise)

Preceding gene: 89055555

Following gene: 89055577

Centisome position: 71.8

GC content: 61.39

Gene sequence:

>777_bases
GTGATATCGCGGGCGCGATTATGCTTGAGAGGTGGCATGGACGGTAAATCAGAACCACACGAGCCTATTCGCCGTCCCAA
ATTGGGGGAGGAAGTGCGCGACCGACTTCTCGCCATCTTGGATTCCGGCGACCTGTCACCCGGAGATCGCTTTCCGTCAG
AACGCGAATTGATGGCCCGTTTCGATGTGGGCCGACCCGCCGTGCGCGAAGCCATGCAATCTCTGCAGGGGATGGGTCTG
ATCGACGTCCGGCACGGCGAACGCCCCCGCGTCTCGAAACCCACCCTTGCCGGCAGCCTCGCCCTTGTCGAGCGCAGCAT
GCGGCAAGCCCTGTCCCTGTCAGAGCCGGAGCTGGAAGACCTCAAGAAGGTTCGGCTGATGGCGGAAGGCTATATGGCCC
GCCTCGCCGCACGGCACCGAACGGACGACCATGTCGCAGACTTGAGGGACATCCTGTCGCGACAGGAACACGCCGCTGGC
ACGGAAGTTGAGACGTTCACGCGGCTTGATGGTGAATTCCACAACGCAATCGCCCGGAGCGCGGGCAACCCCGTGATGGT
GTATTTCATCGACGCCATCTTCAAATGGCTCAAGGAATTCCATATCCAGTCGGTTCATCAGCCGGGCTTGGAAGCGCTCA
CGATTGCCGAACACCAGGACATACTGGCCGCCATAGAGGCCCAGAACGGCTCCGCTGCGCATCGCGCGATGAACAACCAC
CTCAGCCGGGCGAACGCGCTCTATCAAAGCGCCCACCGTCAGGCCGCCGATAGTTAA

Upstream 100 bases:

>100_bases
TACATCATTCTTATCTTTCACCATCTCACTCCGACATGCATATCATAGTATCTCATCAACATGTCATACCACTTATAAGA
TAGCCAGGATAGGGGAAGTT

Downstream 100 bases:

>100_bases
TGGGCGGAACGAAGAAGCCTGTCTGATCCGTCAGCCTCACCATGTGGCAAGACATCTCAACGGGAGTCCTCCATGCCCCA
TCTCGATCACACAGTTTTGT

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MISRARLCLRGGMDGKSEPHEPIRRPKLGEEVRDRLLAILDSGDLSPGDRFPSERELMARFDVGRPAVREAMQSLQGMGL
IDVRHGERPRVSKPTLAGSLALVERSMRQALSLSEPELEDLKKVRLMAEGYMARLAARHRTDDHVADLRDILSRQEHAAG
TEVETFTRLDGEFHNAIARSAGNPVMVYFIDAIFKWLKEFHIQSVHQPGLEALTIAEHQDILAAIEAQNGSAAHRAMNNH
LSRANALYQSAHRQAADS

Sequences:

>Translated_258_residues
MISRARLCLRGGMDGKSEPHEPIRRPKLGEEVRDRLLAILDSGDLSPGDRFPSERELMARFDVGRPAVREAMQSLQGMGL
IDVRHGERPRVSKPTLAGSLALVERSMRQALSLSEPELEDLKKVRLMAEGYMARLAARHRTDDHVADLRDILSRQEHAAG
TEVETFTRLDGEFHNAIARSAGNPVMVYFIDAIFKWLKEFHIQSVHQPGLEALTIAEHQDILAAIEAQNGSAAHRAMNNH
LSRANALYQSAHRQAADS
>Mature_258_residues
MISRARLCLRGGMDGKSEPHEPIRRPKLGEEVRDRLLAILDSGDLSPGDRFPSERELMARFDVGRPAVREAMQSLQGMGL
IDVRHGERPRVSKPTLAGSLALVERSMRQALSLSEPELEDLKKVRLMAEGYMARLAARHRTDDHVADLRDILSRQEHAAG
TEVETFTRLDGEFHNAIARSAGNPVMVYFIDAIFKWLKEFHIQSVHQPGLEALTIAEHQDILAAIEAQNGSAAHRAMNNH
LSRANALYQSAHRQAADS

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=244, Percent_Identity=31.5573770491803, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786303, Length=187, Percent_Identity=30.4812834224599, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=27.8761061946903, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790780, Length=232, Percent_Identity=28.0172413793103, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28777; Mature: 28777

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRARLCLRGGMDGKSEPHEPIRRPKLGEEVRDRLLAILDSGDLSPGDRFPSERELMAR
CCCHHHHHHHCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FDVGRPAVREAMQSLQGMGLIDVRHGERPRVSKPTLAGSLALVERSMRQALSLSEPELED
HCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
LKKVRLMAEGYMARLAARHRTDDHVADLRDILSRQEHAAGTEVETFTRLDGEFHNAIARS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHC
AGNPVMVYFIDAIFKWLKEFHIQSVHQPGLEALTIAEHQDILAAIEAQNGSAAHRAMNNH
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LSRANALYQSAHRQAADS
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISRARLCLRGGMDGKSEPHEPIRRPKLGEEVRDRLLAILDSGDLSPGDRFPSERELMAR
CCCHHHHHHHCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FDVGRPAVREAMQSLQGMGLIDVRHGERPRVSKPTLAGSLALVERSMRQALSLSEPELED
HCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
LKKVRLMAEGYMARLAARHRTDDHVADLRDILSRQEHAAGTEVETFTRLDGEFHNAIARS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHC
AGNPVMVYFIDAIFKWLKEFHIQSVHQPGLEALTIAEHQDILAAIEAQNGSAAHRAMNNH
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LSRANALYQSAHRQAADS
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA