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The map label for this gene is cobO [H]

Identifier: 89055426

GI number: 89055426

Start: 2958161

End: 2958853

Strand: Direct

Name: cobO [H]

Synonym: Jann_2935

Alternate gene names: 89055426

Gene position: 2958161-2958853 (Clockwise)

Preceding gene: 89055417

Following gene: 89055427

Centisome position: 68.51

GC content: 58.44

Gene sequence:

>693_bases
ATGGGGCGCGGGCCTTGTCAATCTGTGCGATTGCGGACAAGCCTTCGGTCAGGCCGCAGGAGGACCGAAGACATGACCGA
AGACACCACCGCCGAGAACGCCCGTCACACCGAGAAGATGCGCAAGATCAAAGCGGCGCGCGACAAGATGATGGAGACCA
AGACCGAAGAAAAAGGTCTGATCATGGTCCATACGGGGCCGGGCAAGGGAAAGTCATCCAGCGGATTCGGGATGGTCATG
CGGTCCATTCAGCACGGCATGGGCTGCGCCGTGGTGCAGTTCATCAAGGGCAATTGGGCGACCGGCGAAAAGAGCTTCCT
GCGCGAGCGTTTCGCCGATGAGTGCCGGTTTTTTGTGTCTGGCGAAGGATTTACCTGGGAGACCCAGGACAAGGAGCGCG
ACATCGCCGCCGCGCAAAACGGCTGGACCATCGCGCAAGAGCAGATCCTGGACCCGGAGATTGATTTCGTGCTGCTCGAT
GAGATCAACATCGCCCTGCGTTATGATTATCTGGACATCGACGAGGTCGTGGACTTTCTGCTGACCCGCAAGCCGCGGAT
GACCCACGTCTGCCTGACAGGTCGCAATGCAAAGCCAGAATTGATTGAGGCCGCCGATCTGGTGACGGAAATGACGCTGA
TCAAGCATCCATTCCGCGACGGCGTAAAAGCCCAGAAAGGCGTGGAGTTCTGA

Upstream 100 bases:

>100_bases
CAGGTCCGCTCACCGCTTACAGTTGCGGGGGCAGCCGCGGGGTTTCACCGCGTTCCCTCTTAGGCCCTCCAAGAAGGGCA
CCATCGCCGTGACCCTGTTC

Downstream 100 bases:

>100_bases
TGCCCAAAATCGGCACGCCCATAGTTGAAGAAGGCCACGATGAGATCGGGCGCTTCCGCGCCGAGTTGCTGTCTGACACG
GGCGGGCTGACCCAATTCGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MGRGPCQSVRLRTSLRSGRRRTEDMTEDTTAENARHTEKMRKIKAARDKMMETKTEEKGLIMVHTGPGKGKSSSGFGMVM
RSIQHGMGCAVVQFIKGNWATGEKSFLRERFADECRFFVSGEGFTWETQDKERDIAAAQNGWTIAQEQILDPEIDFVLLD
EINIALRYDYLDIDEVVDFLLTRKPRMTHVCLTGRNAKPELIEAADLVTEMTLIKHPFRDGVKAQKGVEF

Sequences:

>Translated_230_residues
MGRGPCQSVRLRTSLRSGRRRTEDMTEDTTAENARHTEKMRKIKAARDKMMETKTEEKGLIMVHTGPGKGKSSSGFGMVM
RSIQHGMGCAVVQFIKGNWATGEKSFLRERFADECRFFVSGEGFTWETQDKERDIAAAQNGWTIAQEQILDPEIDFVLLD
EINIALRYDYLDIDEVVDFLLTRKPRMTHVCLTGRNAKPELIEAADLVTEMTLIKHPFRDGVKAQKGVEF
>Mature_229_residues
GRGPCQSVRLRTSLRSGRRRTEDMTEDTTAENARHTEKMRKIKAARDKMMETKTEEKGLIMVHTGPGKGKSSSGFGMVMR
SIQHGMGCAVVQFIKGNWATGEKSFLRERFADECRFFVSGEGFTWETQDKERDIAAAQNGWTIAQEQILDPEIDFVLLDE
INIALRYDYLDIDEVVDFLLTRKPRMTHVCLTGRNAKPELIEAADLVTEMTLIKHPFRDGVKAQKGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=39.2857142857143, Blast_Score=156, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 26136; Mature: 26005

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRGPCQSVRLRTSLRSGRRRTEDMTEDTTAENARHTEKMRKIKAARDKMMETKTEEKGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IMVHTGPGKGKSSSGFGMVMRSIQHGMGCAVVQFIKGNWATGEKSFLRERFADECRFFVS
EEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEEC
GEGFTWETQDKERDIAAAQNGWTIAQEQILDPEIDFVLLDEINIALRYDYLDIDEVVDFL
CCCCEECCCCCHHHHHHHCCCCCHHHHHCCCCCCCEEEECCCEEEEEECCCCHHHHHHHH
LTRKPRMTHVCLTGRNAKPELIEAADLVTEMTLIKHPFRDGVKAQKGVEF
HCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCC
>Mature Secondary Structure 
GRGPCQSVRLRTSLRSGRRRTEDMTEDTTAENARHTEKMRKIKAARDKMMETKTEEKGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IMVHTGPGKGKSSSGFGMVMRSIQHGMGCAVVQFIKGNWATGEKSFLRERFADECRFFVS
EEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEEC
GEGFTWETQDKERDIAAAQNGWTIAQEQILDPEIDFVLLDEINIALRYDYLDIDEVVDFL
CCCCEECCCCCHHHHHHHCCCCCHHHHHCCCCCCCEEEECCCEEEEEECCCCHHHHHHHH
LTRKPRMTHVCLTGRNAKPELIEAADLVTEMTLIKHPFRDGVKAQKGVEF
HCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]