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The map label for this gene is cobK [H]

Identifier: 89055417

GI number: 89055417

Start: 2948899

End: 2949654

Strand: Direct

Name: cobK [H]

Synonym: Jann_2926

Alternate gene names: 89055417

Gene position: 2948899-2949654 (Clockwise)

Preceding gene: 89055410

Following gene: 89055426

Centisome position: 68.29

GC content: 65.87

Gene sequence:

>756_bases
ATGACACCGAACCTCTTGATCCTGGGCGGCACGACCGAGGCGACGGCCCTGGCGCGGCTGGTGGCCGAGGCGGGGATCAC
AGGCAGAGTGTCCTTTGCGGGCCGGGTGGAGCGGCCCGTGCGCCAACCCCTGCCACAGCGCGTCGGCGGGTTCGGCGGGG
TGGCGGGGCTTGCGACCTATCTGAAAGCTCAAAATATCACCCATGTGGTCGATGCCACCCATCCCTTTGCCGCGCAGATG
AGCCGCAACGCGGTCGACGCCTGCGCCAAGACGGGCGTCCCCCTGCTCGCCCTGACCCGTGCGCCGTGGCGAGCGCGTGA
CGGGGACACCTGGACCTATGTCCCCGACATTGCGGGTGCGGTGGCTGCGCTTGATCGTCCCGCCTGCCGCGTGATGCTGG
CCGTGGGTCGTATGCATCTGGCAGATTTCGCGCCCAATCCGCAGCATTTCTATCTGCTGCGCCTCGTTGACCCTCCAAAG
GGGCCGCTGCCCTTTCCAAACATGGAGGCTCTTGTATCGCGGGGGCCGTTCACAACGGCTGATGACACGGCCCTGATGAA
GACGCATGGTATTGAAATCGTTGTCTCGAAAAACGCTGGCGGGACAGGTGCTTACGCCAAGATTGAGGCCGCGCGAACGT
TGCGGCTGCCCGTGATCATGATCGACCGCCCCGCGATCCCGGCGGGGGCCAGCGTGTCGAGGCCGGAGGAGGTTTTGGCG
TGGCTCGGTCATTTCGCCACCGACCGTGGCGTGTAA

Upstream 100 bases:

>100_bases
GATGATTTCCGCCGCCGCCAGCGCGTCCCGGCTTGCAGGCGGCAGCCCCTCCGGTCCATCTTCGCCGAGCCCGATGATCG
TGATCCACGGAAGGTTAGCC

Downstream 100 bases:

>100_bases
ACGAGGGGCGCGTCGTCCCGTGCAATCACACGGGTCAGCGAGGAACCAACGATCACCATCGTCTGCATGTCCGCCATCTC
TGGCGTGGCGTCTGCGAGAG

Product: precorrin-6A reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTPNLLILGGTTEATALARLVAEAGITGRVSFAGRVERPVRQPLPQRVGGFGGVAGLATYLKAQNITHVVDATHPFAAQM
SRNAVDACAKTGVPLLALTRAPWRARDGDTWTYVPDIAGAVAALDRPACRVMLAVGRMHLADFAPNPQHFYLLRLVDPPK
GPLPFPNMEALVSRGPFTTADDTALMKTHGIEIVVSKNAGGTGAYAKIEAARTLRLPVIMIDRPAIPAGASVSRPEEVLA
WLGHFATDRGV

Sequences:

>Translated_251_residues
MTPNLLILGGTTEATALARLVAEAGITGRVSFAGRVERPVRQPLPQRVGGFGGVAGLATYLKAQNITHVVDATHPFAAQM
SRNAVDACAKTGVPLLALTRAPWRARDGDTWTYVPDIAGAVAALDRPACRVMLAVGRMHLADFAPNPQHFYLLRLVDPPK
GPLPFPNMEALVSRGPFTTADDTALMKTHGIEIVVSKNAGGTGAYAKIEAARTLRLPVIMIDRPAIPAGASVSRPEEVLA
WLGHFATDRGV
>Mature_250_residues
TPNLLILGGTTEATALARLVAEAGITGRVSFAGRVERPVRQPLPQRVGGFGGVAGLATYLKAQNITHVVDATHPFAAQMS
RNAVDACAKTGVPLLALTRAPWRARDGDTWTYVPDIAGAVAALDRPACRVMLAVGRMHLADFAPNPQHFYLLRLVDPPKG
PLPFPNMEALVSRGPFTTADDTALMKTHGIEIVVSKNAGGTGAYAKIEAARTLRLPVIMIDRPAIPAGASVSRPEEVLAW
LGHFATDRGV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26582; Mature: 26451

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPNLLILGGTTEATALARLVAEAGITGRVSFAGRVERPVRQPLPQRVGGFGGVAGLATY
CCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHCCHHHCCCHHHHCCCCCHHHHHHH
LKAQNITHVVDATHPFAAQMSRNAVDACAKTGVPLLALTRAPWRARDGDTWTYVPDIAGA
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCHHHHH
VAALDRPACRVMLAVGRMHLADFAPNPQHFYLLRLVDPPKGPLPFPNMEALVSRGPFTTA
HHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCC
DDTALMKTHGIEIVVSKNAGGTGAYAKIEAARTLRLPVIMIDRPAIPAGASVSRPEEVLA
CCCEEEEECCEEEEEECCCCCCCCEEEEEEHHEEECCEEEEECCCCCCCCCCCCHHHHHH
WLGHFATDRGV
HHHHHHHCCCC
>Mature Secondary Structure 
TPNLLILGGTTEATALARLVAEAGITGRVSFAGRVERPVRQPLPQRVGGFGGVAGLATY
CCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHCCHHHCCCHHHHCCCCCHHHHHHH
LKAQNITHVVDATHPFAAQMSRNAVDACAKTGVPLLALTRAPWRARDGDTWTYVPDIAGA
HHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCHHHHH
VAALDRPACRVMLAVGRMHLADFAPNPQHFYLLRLVDPPKGPLPFPNMEALVSRGPFTTA
HHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCC
DDTALMKTHGIEIVVSKNAGGTGAYAKIEAARTLRLPVIMIDRPAIPAGASVSRPEEVLA
CCCEEEEECCEEEEEECCCCCCCCEEEEEEHHEEECCEEEEECCCCCCCCCCCCHHHHHH
WLGHFATDRGV
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]