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The map label for this gene is dprE1 [H]

Identifier: 89055322

GI number: 89055322

Start: 2847785

End: 2849083

Strand: Direct

Name: dprE1 [H]

Synonym: Jann_2831

Alternate gene names: 89055322

Gene position: 2847785-2849083 (Clockwise)

Preceding gene: 89055321

Following gene: 89055323

Centisome position: 65.95

GC content: 64.2

Gene sequence:

>1299_bases
ATGAAGTTGAGCGGCTGGGGACGATTTCCAAACGTCGATTGCACCGTGCGCGTGGCCCGGTCGGAGGTTGACGTGCGCGC
TGCCGTTGCGGCCTCCCCCCTGATCGCGCGCGGCAATGGGCGGGCCTATGGCGACGCGGCGCTGAACCGCGGGCTCACGC
TGGACATGACCGGCATGGACCGGATGCTGTCGTTTGAAGATGGCGTTCTGGTGGCCGAGGCGGGCGTGCTTCTGGGCGAT
ATCATCCACACTTTCCTGCCACGCGGCTGGTTTCCCATGGTCACTCCGGGCACGAAATACGTCAGCCTTGGCGGTGCGAT
CGCGGCGGATGTCCATGGCAAGAACCACCACCTGGACGGCTCGTTCCGGTCCTGTGTGGATTGGGTGGATCTGATGGGCC
CGGACGGAGCCGTGACCCGCGTGACCCGCGAGGATGACCTGTTTGACTGGACGTTGGGGGGCATGGGGTTGACCGGTGTG
ATCCTGCGCGCCCAGATCCGCCTGCGCGCGGTCGAGACCAGCTTCATCGCGCAGGAGACGCGGGCTTTGACATCGCTTAC
CGATACGCTGGAGGCCTTCGAGGACACGCTGGACGCACTCTATTCGGTGGCCTGGATTGACTGCTCGGACGGGCCGCATC
ACGGACACTCCCTTCTGTTGCTGGGTCGGCACGCGACCCCGGGCGATCTTCCCAAACGGCAAAAGCCGTTGGAGGTGAAG
CGCAGGGCCAAGCTGCCCGTGCCCTTCGGCGCACCGCCGTTCCTGTTTCGCGGCCTCTGGCTGCGGGCGCTCAACGGCAT
CTATTGGCGACGCGGGGCAAAACGCGCAGGCCACACGATTGTGGATTGGGACAGCTACTTCTACCCGCTTGACGCGCTGG
CCAACTGGAACCGGCTCTATGGCCGCAACGGCTTCTTGCAATTCCAATGCGCCCTGCCGCTGGAGACTGCCGCCGATGGC
CTCGCCGCCCTGATGGCCGAGATTGCGGCGTCACAATCAGGGTCCGTTCTTTCGGTCCTGAAACGCTTCGGGCCGCAATC
GGGCCATTTTTCCTTCCCAATGCCGGGCTACACCTTGGCCCTCGACTTCCCGGCAAACGAACGGAGCCTTGCCCTGATGG
AACGATTGGACGCGATCACATTGGCCCATAAGGGTCGCTTTTACCTGGCCAAAGACGCCCGTATGCCAGAGGCCGTCGTC
AAAGCCGATGCGCGGGCGGAGGCTTTTGCCGCAATGCGCACGCAGATGGGCCTGCGGGACCGGTTCGCCTCGGAGCAGTC
TGAAAGGTTGGGGTTATGA

Upstream 100 bases:

>100_bases
AGATCGGGGCGGTGATCGGCCTGACCATCGGCTATATCACCAAGTACCAGCTTGACCGTCGGTTCGTGTTCAAAGACGCC
ATGTTCCGAGACACCGCGCC

Downstream 100 bases:

>100_bases
GCGGCCCGGTCCTGATCCTTGGCGCGAAATCGGACATCGCGCGCGCCGTGGCACGGTCCTTCGCCGAAGCCGGTCACCCG
ATCCAGCTGGCCGCCCGCGA

Product: FAD linked oxidase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKLSGWGRFPNVDCTVRVARSEVDVRAAVAASPLIARGNGRAYGDAALNRGLTLDMTGMDRMLSFEDGVLVAEAGVLLGD
IIHTFLPRGWFPMVTPGTKYVSLGGAIAADVHGKNHHLDGSFRSCVDWVDLMGPDGAVTRVTREDDLFDWTLGGMGLTGV
ILRAQIRLRAVETSFIAQETRALTSLTDTLEAFEDTLDALYSVAWIDCSDGPHHGHSLLLLGRHATPGDLPKRQKPLEVK
RRAKLPVPFGAPPFLFRGLWLRALNGIYWRRGAKRAGHTIVDWDSYFYPLDALANWNRLYGRNGFLQFQCALPLETAADG
LAALMAEIAASQSGSVLSVLKRFGPQSGHFSFPMPGYTLALDFPANERSLALMERLDAITLAHKGRFYLAKDARMPEAVV
KADARAEAFAAMRTQMGLRDRFASEQSERLGL

Sequences:

>Translated_432_residues
MKLSGWGRFPNVDCTVRVARSEVDVRAAVAASPLIARGNGRAYGDAALNRGLTLDMTGMDRMLSFEDGVLVAEAGVLLGD
IIHTFLPRGWFPMVTPGTKYVSLGGAIAADVHGKNHHLDGSFRSCVDWVDLMGPDGAVTRVTREDDLFDWTLGGMGLTGV
ILRAQIRLRAVETSFIAQETRALTSLTDTLEAFEDTLDALYSVAWIDCSDGPHHGHSLLLLGRHATPGDLPKRQKPLEVK
RRAKLPVPFGAPPFLFRGLWLRALNGIYWRRGAKRAGHTIVDWDSYFYPLDALANWNRLYGRNGFLQFQCALPLETAADG
LAALMAEIAASQSGSVLSVLKRFGPQSGHFSFPMPGYTLALDFPANERSLALMERLDAITLAHKGRFYLAKDARMPEAVV
KADARAEAFAAMRTQMGLRDRFASEQSERLGL
>Mature_432_residues
MKLSGWGRFPNVDCTVRVARSEVDVRAAVAASPLIARGNGRAYGDAALNRGLTLDMTGMDRMLSFEDGVLVAEAGVLLGD
IIHTFLPRGWFPMVTPGTKYVSLGGAIAADVHGKNHHLDGSFRSCVDWVDLMGPDGAVTRVTREDDLFDWTLGGMGLTGV
ILRAQIRLRAVETSFIAQETRALTSLTDTLEAFEDTLDALYSVAWIDCSDGPHHGHSLLLLGRHATPGDLPKRQKPLEVK
RRAKLPVPFGAPPFLFRGLWLRALNGIYWRRGAKRAGHTIVDWDSYFYPLDALANWNRLYGRNGFLQFQCALPLETAADG
LAALMAEIAASQSGSVLSVLKRFGPQSGHFSFPMPGYTLALDFPANERSLALMERLDAITLAHKGRFYLAKDARMPEAVV
KADARAEAFAAMRTQMGLRDRFASEQSERLGL

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 47357; Mature: 47357

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSGWGRFPNVDCTVRVARSEVDVRAAVAASPLIARGNGRAYGDAALNRGLTLDMTGMD
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCEEECCCCCEECHHHHCCCCEEEECCCH
RMLSFEDGVLVAEAGVLLGDIIHTFLPRGWFPMVTPGTKYVSLGGAIAADVHGKNHHLDG
HHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCC
SFRSCVDWVDLMGPDGAVTRVTREDDLFDWTLGGMGLTGVILRAQIRLRAVETSFIAQET
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RALTSLTDTLEAFEDTLDALYSVAWIDCSDGPHHGHSLLLLGRHATPGDLPKRQKPLEVK
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
RRAKLPVPFGAPPFLFRGLWLRALNGIYWRRGAKRAGHTIVDWDSYFYPLDALANWNRLY
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEHHHHHCHHHHH
GRNGFLQFQCALPLETAADGLAALMAEIAASQSGSVLSVLKRFGPQSGHFSFPMPGYTLA
CCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEE
LDFPANERSLALMERLDAITLAHKGRFYLAKDARMPEAVVKADARAEAFAAMRTQMGLRD
EECCCCCHHHHHHHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RFASEQSERLGL
HHHCCHHHHCCC
>Mature Secondary Structure
MKLSGWGRFPNVDCTVRVARSEVDVRAAVAASPLIARGNGRAYGDAALNRGLTLDMTGMD
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCEEECCCCCEECHHHHCCCCEEEECCCH
RMLSFEDGVLVAEAGVLLGDIIHTFLPRGWFPMVTPGTKYVSLGGAIAADVHGKNHHLDG
HHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCC
SFRSCVDWVDLMGPDGAVTRVTREDDLFDWTLGGMGLTGVILRAQIRLRAVETSFIAQET
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RALTSLTDTLEAFEDTLDALYSVAWIDCSDGPHHGHSLLLLGRHATPGDLPKRQKPLEVK
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
RRAKLPVPFGAPPFLFRGLWLRALNGIYWRRGAKRAGHTIVDWDSYFYPLDALANWNRLY
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEHHHHHCHHHHH
GRNGFLQFQCALPLETAADGLAALMAEIAASQSGSVLSVLKRFGPQSGHFSFPMPGYTLA
CCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEE
LDFPANERSLALMERLDAITLAHKGRFYLAKDARMPEAVVKADARAEAFAAMRTQMGLRD
EECCCCCHHHHHHHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RFASEQSERLGL
HHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]