| Definition | Jannaschia sp. CCS1 chromosome, complete genome. |
|---|---|
| Accession | NC_007802 |
| Length | 4,317,977 |
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The map label for this gene is yqhE [C]
Identifier: 89055073
GI number: 89055073
Start: 2591765
End: 2592595
Strand: Reverse
Name: yqhE [C]
Synonym: Jann_2582
Alternate gene names: 89055073
Gene position: 2592595-2591765 (Counterclockwise)
Preceding gene: 89055074
Following gene: 89055071
Centisome position: 60.04
GC content: 60.05
Gene sequence:
>831_bases ATGACCGATAGGCCGGTGATCAAATTTCATGACGGCGCGCAGATCCCGCAAGTGGGCTTTGGGATCTGGCAGGTGCCCCA GGACATCGCCGGAGAGACCGTGCGCAGTGCCATCGAGATCGGCTACCGGATGATCGACGGCGCTTACCTCTATATGAATG AAGCGGGCTTGGGCGAGGGGCTGCGTGCTTCAGGCCTTCCGCGGGACGAGGTCTTTGTGACCACCAAAGTCTGGAATAAT GAGCAGGGGGCCGCGAAGGCCCGCGCCTCGGTTGAGCGGAGCCTGAAAACCATTGGTGTGGAGCAGTTGGATCTGGTGTT GATCCATTGGCCGGTGCCGAGCCAGGACCTGTATCTGGAAACATGGAAGGCCTTCCAGGATATGCGTGATGAGGGGCTGA TGCGCTCCATTGGGACGTCAAATTTCAACGCGGACCATCTGGAACGGATCATCGCCGAGACCGGAGAAGCGCCTGTCCTC AACCAGATTGAGCTGAACCCGATGTTGCAACAGCCGGAGATGCGCGCAGTTCACAAGGCCCACGGGGTCGTCACGCAGGC CTGGACGCCCCTTGGCAATGCGCGCTCCTTTGAGGCGGAGCCGATCACCAAGGCGGTTGCGCGCACGGGCAAAAGCCCCG TGCAGGTGATCCTGCGATGGCATGTGCAATTGGGCAATGCGGTCATCCCACGCTCGGTGAAGGCCCATCGGCAGGCGGAA AACCTGGATGTATTCGACTTTACGCTGACAGAAGCGGAAATGTCCGAGATCGCGACGCTGGATATGGGCCTGCGCACAGG GCCGGATCCGTCTGTCTTCAAGATGATGTAG
Upstream 100 bases:
>100_bases TGCGATCCAGTTGGGCTTCGCCGCAGACACGGTGCACCCGTTTGACGCTACGACCGGGCAACGAGTAGGCTCGGCCTGAA AAACCAAAAGGATCAAAGAC
Downstream 100 bases:
>100_bases GGCTGCCGCTCAGGCCAGTTGGAACTGTTTGCGGAACTCGGACGGGGATGTATGGATCTGCCGCAGAAAGGCGCGGCGCA TCCGTTCCACATCCAGAAAT
Product: aldo/keto reductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 276; Mature: 275
Protein sequence:
>276_residues MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEGLRASGLPRDEVFVTTKVWNN EQGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVL NQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGNARSFEAEPITKAVARTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAE NLDVFDFTLTEAEMSEIATLDMGLRTGPDPSVFKMM
Sequences:
>Translated_276_residues MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEGLRASGLPRDEVFVTTKVWNN EQGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVL NQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGNARSFEAEPITKAVARTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAE NLDVFDFTLTEAEMSEIATLDMGLRTGPDPSVFKMM >Mature_275_residues TDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEGLRASGLPRDEVFVTTKVWNNE QGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLN QIELNPMLQQPEMRAVHKAHGVVTQAWTPLGNARSFEAEPITKAVARTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAEN LDVFDFTLTEAEMSEIATLDMGLRTGPDPSVFKMM
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI5174695, Length=298, Percent_Identity=33.2214765100671, Blast_Score=174, Evalue=7e-44, Organism=Homo sapiens, GI24497577, Length=293, Percent_Identity=32.0819112627986, Blast_Score=173, Evalue=2e-43, Organism=Homo sapiens, GI5174391, Length=293, Percent_Identity=32.0819112627986, Blast_Score=173, Evalue=2e-43, Organism=Homo sapiens, GI223468663, Length=287, Percent_Identity=32.404181184669, Blast_Score=169, Evalue=3e-42, Organism=Homo sapiens, GI93277124, Length=303, Percent_Identity=32.013201320132, Blast_Score=168, Evalue=4e-42, Organism=Homo sapiens, GI310109922, Length=280, Percent_Identity=34.2857142857143, Blast_Score=166, Evalue=3e-41, Organism=Homo sapiens, GI5453543, Length=298, Percent_Identity=32.8859060402685, Blast_Score=164, Evalue=6e-41, Organism=Homo sapiens, GI310109920, Length=298, Percent_Identity=32.8859060402685, Blast_Score=164, Evalue=7e-41, Organism=Homo sapiens, GI45446745, Length=298, Percent_Identity=32.5503355704698, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI4503285, Length=298, Percent_Identity=32.5503355704698, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI4502049, Length=291, Percent_Identity=33.6769759450172, Blast_Score=160, Evalue=1e-39, Organism=Homo sapiens, GI24497583, Length=297, Percent_Identity=31.986531986532, Blast_Score=155, Evalue=5e-38, Organism=Homo sapiens, GI300116273, Length=277, Percent_Identity=32.129963898917, Blast_Score=151, Evalue=6e-37, Organism=Homo sapiens, GI291291012, Length=268, Percent_Identity=31.7164179104478, Blast_Score=151, Evalue=8e-37, Organism=Homo sapiens, GI24497585, Length=298, Percent_Identity=31.2080536912752, Blast_Score=149, Evalue=2e-36, Organism=Homo sapiens, GI300116271, Length=281, Percent_Identity=30.2491103202847, Blast_Score=134, Evalue=1e-31, Organism=Homo sapiens, GI310109926, Length=126, Percent_Identity=38.0952380952381, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI207028673, Length=126, Percent_Identity=37.3015873015873, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI310109924, Length=153, Percent_Identity=32.6797385620915, Blast_Score=84, Evalue=2e-16, Organism=Escherichia coli, GI87082198, Length=275, Percent_Identity=43.6363636363636, Blast_Score=256, Evalue=1e-69, Organism=Escherichia coli, GI1786400, Length=253, Percent_Identity=35.9683794466403, Blast_Score=166, Evalue=1e-42, Organism=Escherichia coli, GI1788081, Length=278, Percent_Identity=27.6978417266187, Blast_Score=80, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17537077, Length=292, Percent_Identity=34.9315068493151, Blast_Score=171, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17537075, Length=298, Percent_Identity=34.2281879194631, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17537079, Length=298, Percent_Identity=29.5302013422819, Blast_Score=162, Evalue=2e-40, Organism=Caenorhabditis elegans, GI17552492, Length=275, Percent_Identity=32, Blast_Score=151, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17564128, Length=298, Percent_Identity=31.5436241610738, Blast_Score=149, Evalue=1e-36, Organism=Caenorhabditis elegans, GI17550248, Length=283, Percent_Identity=30.3886925795053, Blast_Score=146, Evalue=9e-36, Organism=Caenorhabditis elegans, GI71998625, Length=262, Percent_Identity=27.8625954198473, Blast_Score=142, Evalue=1e-34, Organism=Caenorhabditis elegans, GI17566692, Length=285, Percent_Identity=30.8771929824561, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17562292, Length=279, Percent_Identity=31.1827956989247, Blast_Score=135, Evalue=2e-32, Organism=Caenorhabditis elegans, GI17538386, Length=275, Percent_Identity=30.9090909090909, Blast_Score=134, Evalue=4e-32, Organism=Caenorhabditis elegans, GI17561298, Length=272, Percent_Identity=29.0441176470588, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17561300, Length=273, Percent_Identity=27.8388278388278, Blast_Score=121, Evalue=4e-28, Organism=Saccharomyces cerevisiae, GI6322556, Length=257, Percent_Identity=33.0739299610895, Blast_Score=174, Evalue=1e-44, Organism=Saccharomyces cerevisiae, GI6324694, Length=278, Percent_Identity=32.0143884892086, Blast_Score=173, Evalue=3e-44, Organism=Saccharomyces cerevisiae, GI6320576, Length=284, Percent_Identity=32.0422535211268, Blast_Score=172, Evalue=7e-44, Organism=Saccharomyces cerevisiae, GI6321896, Length=308, Percent_Identity=30.5194805194805, Blast_Score=157, Evalue=2e-39, Organism=Saccharomyces cerevisiae, GI6319625, Length=288, Percent_Identity=29.1666666666667, Blast_Score=127, Evalue=2e-30, Organism=Saccharomyces cerevisiae, GI6320079, Length=238, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=2e-23, Organism=Drosophila melanogaster, GI24663317, Length=295, Percent_Identity=33.5593220338983, Blast_Score=177, Evalue=5e-45, Organism=Drosophila melanogaster, GI24657054, Length=292, Percent_Identity=34.2465753424658, Blast_Score=173, Evalue=1e-43, Organism=Drosophila melanogaster, GI20129731, Length=290, Percent_Identity=35.1724137931034, Blast_Score=172, Evalue=2e-43, Organism=Drosophila melanogaster, GI45553081, Length=291, Percent_Identity=31.9587628865979, Blast_Score=171, Evalue=5e-43, Organism=Drosophila melanogaster, GI24662781, Length=296, Percent_Identity=34.1216216216216, Blast_Score=164, Evalue=4e-41, Organism=Drosophila melanogaster, GI24662789, Length=296, Percent_Identity=31.0810810810811, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI21356425, Length=298, Percent_Identity=30.8724832214765, Blast_Score=160, Evalue=7e-40, Organism=Drosophila melanogaster, GI24662785, Length=296, Percent_Identity=33.7837837837838, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI24644950, Length=305, Percent_Identity=30.1639344262295, Blast_Score=150, Evalue=6e-37, Organism=Drosophila melanogaster, GI281366140, Length=256, Percent_Identity=32.8125, Blast_Score=150, Evalue=1e-36, Organism=Drosophila melanogaster, GI221378297, Length=325, Percent_Identity=28.6153846153846, Blast_Score=145, Evalue=4e-35,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 30697; Mature: 30566
Theoretical pI: Translated: 5.39; Mature: 5.39
Prosite motif: PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 4.0 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG CCCCCEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQDLYLE CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHH TWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKA HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH HGVVTQAWTPLGNARSFEAEPITKAVARTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAE HCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCHHHHHHHHC NLDVFDFTLTEAEMSEIATLDMGLRTGPDPSVFKMM CCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCEECC >Mature Secondary Structure TDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG CCCCEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQDLYLE CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHH TWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKA HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH HGVVTQAWTPLGNARSFEAEPITKAVARTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAE HCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCHHHHHHHHC NLDVFDFTLTEAEMSEIATLDMGLRTGPDPSVFKMM CCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA