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The map label for this gene is yciR [C]

Identifier: 89055066

GI number: 89055066

Start: 2584190

End: 2585890

Strand: Reverse

Name: yciR [C]

Synonym: Jann_2575

Alternate gene names: 89055066

Gene position: 2585890-2584190 (Counterclockwise)

Preceding gene: 89055067

Following gene: 89055065

Centisome position: 59.89

GC content: 61.96

Gene sequence:

>1701_bases
GTGGCGGAAAAGCTGCAATTGGCTGTGGAAGCATCGCAGATGGGGGTCTGGGAGTTCGATGAAGCCACCGGTCGTGTCCA
TTGGGATGACCGGATGCTGGAGATCTACGGGATCGAGGATGGGTTGAACGTCCGCCCCGACGATTTCTGGGAAAGCCATT
TGCATCCTGACGATCTGGAAGCAACGGTCGCCTACGCCGAAAAATGCAAGATCGAGAATACGGACTTTCGCCGCGATTAC
CGCATCCTGCGGGAAGATGGCGGGGTGCGCCATATCCGCAGCCTTGCCCGCAGTGTGGTCACGCCCGGGCACCCCAGCCG
TCTGATCGGCGTGAATATCGACGTCACCAAGGATTATCTGCGGGCGGAGGAATTGCAGAAGGCGCAGCGCCAGCTGAAGT
ATGACGCCCGCCATGACGCGCTGACCGGGCTTGGCAACCGGCGCAGCCTGGACGAGATGACGCTGACGCTGTTCAACCGG
CTTGGCCCGAAGGACCGCTATTGCGTGATGCATCTGGACTTGGATCATTTCAAAGAGGTCAATGACACTCTGGGCCACAT
GGCCGGTGATCATGTGCTGGCCGCGATCGCGACGGCTCTGGGCCGGGTCATCGGCAAGCTGGGGACGTGCTTCCGCGTCG
GTGGCGATGAATTCGCGGTGCTGTTCAAGTCCGCTCCCGATGAGCAGGTCATCATCGGTTTGTGCGAAGAGTTGGTGCAG
GATTGTGCCGCGCCGCAGGTGTTTGAGGGGCAGGATTGCTCGGTCAGCGTCAGCATCGGCTATGCCTTTGGCGAAGGCCC
GCCCCACAACCCGTCGGAGGTTTTCGTGAACGCCGACGCGGCCCTTTATGCGGCAAAAAACGCAGGCCGCTCGGGTTATC
AGGCCTATACCGCGCAGATCGGGGAGGCGTCGGCAAAAGCGTCCAACGCACGCCAGGATATTCTGGCAGCGATCCGCAAC
GACGAACTCATTTGCCACTACCAGCCGCAATTTGACGCCAGAACCCTCGATGTGGTGGGGGGGGAAGCGCTGGTGCGTTG
GAATTGCCCCAAACGCGGCCTGCTGACACCCGATGCCTTCCTGCCCGAGGCGGAGCGGGCCGGGTTGCTGCCCGAAATTG
ACGCTTGCGTTTTTTCCATCGTCGCCCGCCAGCAAGTGGCCTGGGCCGAGGCGGGCGTTCCCTTCCCGATCATCTCGCTC
AACACCTCCGCCGCACGGCTGCGCGCACCGGACCTGATCGACAGCATCCGCGCGGTGCTGGAGCCGTGTCACAGGATGTC
CCTCGAATTGCTGGAAACGGCCTTTCTGGATGCGCTCGACGATGACCTTGCGTTCAAATTGAACGCCTTGCGCGATCTGG
GACTTCGGATTGAGCTTGATGATTTCGGTTCCGGCCATTCGTCGGTGGCGGCCCTTCAGGCGGTCAGGCCGGATCAGGTA
AAGATCGACCGCAGCCTGATCGCGCCGCTCGCCAGCAACCCCCACCAGATCCAGACCCTGAAGTCGCTGGCCCGCATCGC
CCGGCTGGAGCGGGCGGCTATCGCGATTGAGGGGCTGGAGACGGGCATCCAGATGGCTGCCATTCGCTCTGTGGATTGTG
ATGTCTTGCAGGGCTACACGCTGCAACGTCCCATGCCCGCCGACGATTTTACCGCCCTTCTGATGCGGTCCGACAAGGAC
CTGGACCAGATCCGCGCCTGA

Upstream 100 bases:

>100_bases
CTGACCCGGTCACCGCCATGGCCATTGGAGCAAGAGGTACGTCATCCACGACGATCGTGACAAACGGAAGGTCCCGGCTG
GGAAGGCGGTTCTGTCAGAA

Downstream 100 bases:

>100_bases
CCCACCGCCGCCGCTTGCGACCGGCACGATCCCCACTGGTCTTTCCCGATGGATTTGCGCAAGTTGGTGGCTGACCAGGA
CCTTGAGCGGAGATCACAAT

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MAEKLQLAVEASQMGVWEFDEATGRVHWDDRMLEIYGIEDGLNVRPDDFWESHLHPDDLEATVAYAEKCKIENTDFRRDY
RILREDGGVRHIRSLARSVVTPGHPSRLIGVNIDVTKDYLRAEELQKAQRQLKYDARHDALTGLGNRRSLDEMTLTLFNR
LGPKDRYCVMHLDLDHFKEVNDTLGHMAGDHVLAAIATALGRVIGKLGTCFRVGGDEFAVLFKSAPDEQVIIGLCEELVQ
DCAAPQVFEGQDCSVSVSIGYAFGEGPPHNPSEVFVNADAALYAAKNAGRSGYQAYTAQIGEASAKASNARQDILAAIRN
DELICHYQPQFDARTLDVVGGEALVRWNCPKRGLLTPDAFLPEAERAGLLPEIDACVFSIVARQQVAWAEAGVPFPIISL
NTSAARLRAPDLIDSIRAVLEPCHRMSLELLETAFLDALDDDLAFKLNALRDLGLRIELDDFGSGHSSVAALQAVRPDQV
KIDRSLIAPLASNPHQIQTLKSLARIARLERAAIAIEGLETGIQMAAIRSVDCDVLQGYTLQRPMPADDFTALLMRSDKD
LDQIRA

Sequences:

>Translated_566_residues
MAEKLQLAVEASQMGVWEFDEATGRVHWDDRMLEIYGIEDGLNVRPDDFWESHLHPDDLEATVAYAEKCKIENTDFRRDY
RILREDGGVRHIRSLARSVVTPGHPSRLIGVNIDVTKDYLRAEELQKAQRQLKYDARHDALTGLGNRRSLDEMTLTLFNR
LGPKDRYCVMHLDLDHFKEVNDTLGHMAGDHVLAAIATALGRVIGKLGTCFRVGGDEFAVLFKSAPDEQVIIGLCEELVQ
DCAAPQVFEGQDCSVSVSIGYAFGEGPPHNPSEVFVNADAALYAAKNAGRSGYQAYTAQIGEASAKASNARQDILAAIRN
DELICHYQPQFDARTLDVVGGEALVRWNCPKRGLLTPDAFLPEAERAGLLPEIDACVFSIVARQQVAWAEAGVPFPIISL
NTSAARLRAPDLIDSIRAVLEPCHRMSLELLETAFLDALDDDLAFKLNALRDLGLRIELDDFGSGHSSVAALQAVRPDQV
KIDRSLIAPLASNPHQIQTLKSLARIARLERAAIAIEGLETGIQMAAIRSVDCDVLQGYTLQRPMPADDFTALLMRSDKD
LDQIRA
>Mature_565_residues
AEKLQLAVEASQMGVWEFDEATGRVHWDDRMLEIYGIEDGLNVRPDDFWESHLHPDDLEATVAYAEKCKIENTDFRRDYR
ILREDGGVRHIRSLARSVVTPGHPSRLIGVNIDVTKDYLRAEELQKAQRQLKYDARHDALTGLGNRRSLDEMTLTLFNRL
GPKDRYCVMHLDLDHFKEVNDTLGHMAGDHVLAAIATALGRVIGKLGTCFRVGGDEFAVLFKSAPDEQVIIGLCEELVQD
CAAPQVFEGQDCSVSVSIGYAFGEGPPHNPSEVFVNADAALYAAKNAGRSGYQAYTAQIGEASAKASNARQDILAAIRND
ELICHYQPQFDARTLDVVGGEALVRWNCPKRGLLTPDAFLPEAERAGLLPEIDACVFSIVARQQVAWAEAGVPFPIISLN
TSAARLRAPDLIDSIRAVLEPCHRMSLELLETAFLDALDDDLAFKLNALRDLGLRIELDDFGSGHSSVAALQAVRPDQVK
IDRSLIAPLASNPHQIQTLKSLARIARLERAAIAIEGLETGIQMAAIRSVDCDVLQGYTLQRPMPADDFTALLMRSDKDL
DQIRA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=432, Percent_Identity=28.2407407407407, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87081921, Length=439, Percent_Identity=26.6514806378132, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI87081845, Length=257, Percent_Identity=30.3501945525292, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI226510982, Length=439, Percent_Identity=24.8291571753986, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=29.8804780876494, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081980, Length=269, Percent_Identity=29.368029739777, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788381, Length=408, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787055, Length=256, Percent_Identity=26.171875, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=31.1203319502075, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=27.7310924369748, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=208, Percent_Identity=33.1730769230769, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081881, Length=209, Percent_Identity=34.9282296650718, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786507, Length=252, Percent_Identity=26.984126984127, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=35.7575757575758, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788849, Length=350, Percent_Identity=25.1428571428571, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=31.8681318681319, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=36.9426751592357, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693134, Length=175, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788085, Length=170, Percent_Identity=32.3529411764706, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082096, Length=449, Percent_Identity=21.6035634743875, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=29.1891891891892, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082007, Length=179, Percent_Identity=30.7262569832402, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=154, Percent_Identity=32.4675324675325, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 62444; Mature: 62312

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKLQLAVEASQMGVWEFDEATGRVHWDDRMLEIYGIEDGLNVRPDDFWESHLHPDDLE
CCCHHEEEEEHHHCCCEEECCCCCEEEECCCEEEEEECCCCCCCCCCHHHHHCCCCCCHH
ATVAYAEKCKIENTDFRRDYRILREDGGVRHIRSLARSVVTPGHPSRLIGVNIDVTKDYL
HHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHH
RAEELQKAQRQLKYDARHDALTGLGNRRSLDEMTLTLFNRLGPKDRYCVMHLDLDHFKEV
HHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
NDTLGHMAGDHVLAAIATALGRVIGKLGTCFRVGGDEFAVLFKSAPDEQVIIGLCEELVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHH
DCAAPQVFEGQDCSVSVSIGYAFGEGPPHNPSEVFVNADAALYAAKNAGRSGYQAYTAQI
HCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEECCHHEEEECCCCCCCHHHHHHHH
GEASAKASNARQDILAAIRNDELICHYQPQFDARTLDVVGGEALVRWNCPKRGLLTPDAF
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCHHC
LPEAERAGLLPEIDACVFSIVARQQVAWAEAGVPFPIISLNTSAARLRAPDLIDSIRAVL
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCHHHHHHHHHH
EPCHRMSLELLETAFLDALDDDLAFKLNALRDLGLRIELDDFGSGHSSVAALQAVRPDQV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCE
KIDRSLIAPLASNPHQIQTLKSLARIARLERAAIAIEGLETGIQMAAIRSVDCDVLQGYT
EHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
LQRPMPADDFTALLMRSDKDLDQIRA
CCCCCCCHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
AEKLQLAVEASQMGVWEFDEATGRVHWDDRMLEIYGIEDGLNVRPDDFWESHLHPDDLE
CCHHEEEEEHHHCCCEEECCCCCEEEECCCEEEEEECCCCCCCCCCHHHHHCCCCCCHH
ATVAYAEKCKIENTDFRRDYRILREDGGVRHIRSLARSVVTPGHPSRLIGVNIDVTKDYL
HHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHH
RAEELQKAQRQLKYDARHDALTGLGNRRSLDEMTLTLFNRLGPKDRYCVMHLDLDHFKEV
HHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
NDTLGHMAGDHVLAAIATALGRVIGKLGTCFRVGGDEFAVLFKSAPDEQVIIGLCEELVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHH
DCAAPQVFEGQDCSVSVSIGYAFGEGPPHNPSEVFVNADAALYAAKNAGRSGYQAYTAQI
HCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEECCHHEEEECCCCCCCHHHHHHHH
GEASAKASNARQDILAAIRNDELICHYQPQFDARTLDVVGGEALVRWNCPKRGLLTPDAF
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCHHC
LPEAERAGLLPEIDACVFSIVARQQVAWAEAGVPFPIISLNTSAARLRAPDLIDSIRAVL
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCHHHHHHHHHH
EPCHRMSLELLETAFLDALDDDLAFKLNALRDLGLRIELDDFGSGHSSVAALQAVRPDQV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCE
KIDRSLIAPLASNPHQIQTLKSLARIARLERAAIAIEGLETGIQMAAIRSVDCDVLQGYT
EHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
LQRPMPADDFTALLMRSDKDLDQIRA
CCCCCCCHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]