| Definition | Jannaschia sp. CCS1 chromosome, complete genome. |
|---|---|
| Accession | NC_007802 |
| Length | 4,317,977 |
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The map label for this gene is mrcA [H]
Identifier: 89055025
GI number: 89055025
Start: 2534018
End: 2536582
Strand: Reverse
Name: mrcA [H]
Synonym: Jann_2534
Alternate gene names: 89055025
Gene position: 2536582-2534018 (Counterclockwise)
Preceding gene: 89055027
Following gene: 89055024
Centisome position: 58.74
GC content: 64.41
Gene sequence:
>2565_bases ATGCGATTCATTGTTGGGTTTTTCGGCGCGATTTTCAGCGCAGTCACGTTGGGGCTGGTGTTCGCGGCTCTGGGGGTCGG TGGCCTGTTGTTCACCTACTCGCGTGGCCTGCCGGACCATGAGGCGCTGTCGCAATACGCGCCGCCGACCATCAGCCGCA TCTATTCGCGCCAAGGCATGATCGTGGACGAATTCGCGACCGAACGGCGGCTGTTCACGCCCGCCGAGGAGATCCCGGAT CTGGTCTCGTTCGCCTTCGTCTCCGCCGAGGATCGCAACTTCTACACCCACTCCGGCTATGATCCGCGCGCGATTGTCGC GGCCTTCGTTGATGCCGTGCGCTCTCGCGGGCAGGACGTGCGTGGCGCGTCGACGATCACCCAGCAGGTGATGAAGAATT TCCTTCTCGACAGCTCCCGCACGGTTGAACGGAAGGTGCGCGAGATCATTCTGGCGGCCCGGATCGAACGGACGCTGAGC AAGGACCGCATTCTGGAATTGTACCTGAATGAGATCTTTCTGGGCCAGAATTCCTATGGCGTCACCGCCGCCGCCCAGAC CTATTTCAATGCGACGCTGGAGGATCTGACGTTGGAGCAGGTGGCCTATCTGGCCGCGTTGCCGCAGGCCCCCTCGCGGT TCCACCCGGTCAATGATTACGAGCGTGCTGTGGGCCGCCGCGATTACGTTCTGCGCGAGATGTACGAGAACGGCTATGTG ACGCTGGAAGAGATGGAGGCCGCGCAGGCCATGCCGCTGGAGACAGTGCAGGGTGGCCATATCGAAGGCCGCCGTCTGAC CCGTCCGCCGCGCAACTACTTCACGGACGAGATTCGCCGTCAGCTTTCGGCGCAATACGGGGCGGATGAGTTCTTCTCCG GTGGCTATGCCGTGCGCTCCACCATGGATGAGAGCCTGCAGGAGGTGGCGGAAGCCTCGCTGCGCCGTGCGTTGGAGCGC TATGACCGGAATCTGGGCACCTGGCGCGGGGCCGCTGACACGATTGAGCCCGGTCTGTTAACCGAAGAGGCCAGCTGGCG CGACGCCCTGCGCGGGGCAGAGATCGCGCGCGACGTGGACGGCTGGTTTGCCGCTGTCGTGCTGGAGGTGGGCGATAGTT CGGCCCGGATCGGCATTGAAGGTGTCGAGGACGACGATGACGGCCATTTCATCCCCGCCGAAGACGTGACATGGGCGCGT CCGCTGCTTGAAGACGGCTCGCGCGGGAGTACAGCGCGCGTGGCCGGCGATTTGCTGAGCGTTGGCGACGTGGTCCACGT GCGCCGCATGACCAATGACAGCGATGGCAGCTTCATCCGCTGGACCCTGCGCCAGATCCCCGAGGTGCAGGGCGGCTTCA TGGCCATGGATGTGCATACGGGCCGCGTTCTGGCGATGCAGGGCGGGTTTTCGTACCAGTATTCCAGCTTCAACCGGGCG ACCCAGGCCACGCGCCAGCCGGGCTCCAGCTTCAAGCCGTTCGTCTATGCGGCCGCTCTGGATTCCGGCTATGGCCCCAA CACCATCGTGATTGATGCGCCGATTGAGGTCGCGACAGGTGACGGCATCTGGCGGCCGACGAATGCGTCGAACCAGTTCT ACGGCCCGTCGCCCCTGCGCACGGGGATTGAGCGATCCCGCAATCTGATGACCGTGCGTCTGGCCCAGGATGTGGGCATG GAGACCGTCGCCCGGTATGCCGAGCGGTTCGGCGTCTACGACGATATGCAGCCGTTTCTTGCGAACGCGCTTGGCAGTCA GGAGACGACGCTGTTTCGCATGGTGGCGGCCTACGCGATGTTTGCCAATGGCGGTGAGCGGGTGGAGCCGACGCTGGTGG ACCGGATCCAGAACCGCTATGGCGAAACGGTGTATCGCCATGACCAGCGCCTCTGCCCGGATTGTGGCGAGGCAGAGATC GAGGCGGGCCTCGCGCCCCGGATCGTCTCGACCCGGGAGCGGGTGATCGACCCGATCACCGCCTATCAACTGACGTCGAT GATGCGCGGCGTGGTCCAGCGCGGCACCGCTTCGGGCTCGGTCAATCTCCCGGTGCCCACGGCGGGCAAGACGGGCACGA CAAACGACGCGCGGGACGTTTGGTTTGTGGGCTTCACGTCCAACATCGTGGCGGGCTGCTACATCGGCTATGATCAGCCG GAAAGCCTGGGCCGGGGCGCGTCTGGCGGCGGCATGTGCGGCCCGGTATTCCAACGCTTCATGCTGGAGGCGATCGAGGA ATACGGATCGGGTGATTTTCCGGTGCCCGAGGGCGGCGCGTTTTACCCCATCGACCGCTATTCCGGCGCGCGCCTGCCAA GTGGCGCGTCTGGCGAGAATGTGGTCTACGAATTGTTCCGGGCTGGCGAAGCGCCGTTCGAGGGGCTTTTGTCGGTCATC GATGGCGGGTGGGCGATGTCATCCGACATCCCGATGTTCAGCCAGGAGGGCGGAGATGGCGGCGGTGGCGGTCAGGGCAC TGTGGTGGAAACGTCAGACGGCGACGCCGCGCGGGTGCCGACAAACACCGGCTTTGGCACGCTCAGTTCAGGCGGATTGT ACTGA
Upstream 100 bases:
>100_bases AACGTAACAAAATCGCGGCAAAAACCCGCCCAGTTGCTTTTGACCCAGACCCGCGCCCGGCGTATAAGCACACCCAAGAA TATGGGGATTTGAGCATACT
Downstream 100 bases:
>100_bases CCGCAACCGTCGCGTGCCAGACTTTTGCAAAAGTCTGGCCAAAGCCTTGCAAGGCTTTGGGACGCCCGGAGGGCGCGGTC GTGCATTGAAGGTCGGGGGG
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 854; Mature: 854
Protein sequence:
>854_residues MRFIVGFFGAIFSAVTLGLVFAALGVGGLLFTYSRGLPDHEALSQYAPPTISRIYSRQGMIVDEFATERRLFTPAEEIPD LVSFAFVSAEDRNFYTHSGYDPRAIVAAFVDAVRSRGQDVRGASTITQQVMKNFLLDSSRTVERKVREIILAARIERTLS KDRILELYLNEIFLGQNSYGVTAAAQTYFNATLEDLTLEQVAYLAALPQAPSRFHPVNDYERAVGRRDYVLREMYENGYV TLEEMEAAQAMPLETVQGGHIEGRRLTRPPRNYFTDEIRRQLSAQYGADEFFSGGYAVRSTMDESLQEVAEASLRRALER YDRNLGTWRGAADTIEPGLLTEEASWRDALRGAEIARDVDGWFAAVVLEVGDSSARIGIEGVEDDDDGHFIPAEDVTWAR PLLEDGSRGSTARVAGDLLSVGDVVHVRRMTNDSDGSFIRWTLRQIPEVQGGFMAMDVHTGRVLAMQGGFSYQYSSFNRA TQATRQPGSSFKPFVYAAALDSGYGPNTIVIDAPIEVATGDGIWRPTNASNQFYGPSPLRTGIERSRNLMTVRLAQDVGM ETVARYAERFGVYDDMQPFLANALGSQETTLFRMVAAYAMFANGGERVEPTLVDRIQNRYGETVYRHDQRLCPDCGEAEI EAGLAPRIVSTRERVIDPITAYQLTSMMRGVVQRGTASGSVNLPVPTAGKTGTTNDARDVWFVGFTSNIVAGCYIGYDQP ESLGRGASGGGMCGPVFQRFMLEAIEEYGSGDFPVPEGGAFYPIDRYSGARLPSGASGENVVYELFRAGEAPFEGLLSVI DGGWAMSSDIPMFSQEGGDGGGGGQGTVVETSDGDAARVPTNTGFGTLSSGGLY
Sequences:
>Translated_854_residues MRFIVGFFGAIFSAVTLGLVFAALGVGGLLFTYSRGLPDHEALSQYAPPTISRIYSRQGMIVDEFATERRLFTPAEEIPD LVSFAFVSAEDRNFYTHSGYDPRAIVAAFVDAVRSRGQDVRGASTITQQVMKNFLLDSSRTVERKVREIILAARIERTLS KDRILELYLNEIFLGQNSYGVTAAAQTYFNATLEDLTLEQVAYLAALPQAPSRFHPVNDYERAVGRRDYVLREMYENGYV TLEEMEAAQAMPLETVQGGHIEGRRLTRPPRNYFTDEIRRQLSAQYGADEFFSGGYAVRSTMDESLQEVAEASLRRALER YDRNLGTWRGAADTIEPGLLTEEASWRDALRGAEIARDVDGWFAAVVLEVGDSSARIGIEGVEDDDDGHFIPAEDVTWAR PLLEDGSRGSTARVAGDLLSVGDVVHVRRMTNDSDGSFIRWTLRQIPEVQGGFMAMDVHTGRVLAMQGGFSYQYSSFNRA TQATRQPGSSFKPFVYAAALDSGYGPNTIVIDAPIEVATGDGIWRPTNASNQFYGPSPLRTGIERSRNLMTVRLAQDVGM ETVARYAERFGVYDDMQPFLANALGSQETTLFRMVAAYAMFANGGERVEPTLVDRIQNRYGETVYRHDQRLCPDCGEAEI EAGLAPRIVSTRERVIDPITAYQLTSMMRGVVQRGTASGSVNLPVPTAGKTGTTNDARDVWFVGFTSNIVAGCYIGYDQP ESLGRGASGGGMCGPVFQRFMLEAIEEYGSGDFPVPEGGAFYPIDRYSGARLPSGASGENVVYELFRAGEAPFEGLLSVI DGGWAMSSDIPMFSQEGGDGGGGGQGTVVETSDGDAARVPTNTGFGTLSSGGLY >Mature_854_residues MRFIVGFFGAIFSAVTLGLVFAALGVGGLLFTYSRGLPDHEALSQYAPPTISRIYSRQGMIVDEFATERRLFTPAEEIPD LVSFAFVSAEDRNFYTHSGYDPRAIVAAFVDAVRSRGQDVRGASTITQQVMKNFLLDSSRTVERKVREIILAARIERTLS KDRILELYLNEIFLGQNSYGVTAAAQTYFNATLEDLTLEQVAYLAALPQAPSRFHPVNDYERAVGRRDYVLREMYENGYV TLEEMEAAQAMPLETVQGGHIEGRRLTRPPRNYFTDEIRRQLSAQYGADEFFSGGYAVRSTMDESLQEVAEASLRRALER YDRNLGTWRGAADTIEPGLLTEEASWRDALRGAEIARDVDGWFAAVVLEVGDSSARIGIEGVEDDDDGHFIPAEDVTWAR PLLEDGSRGSTARVAGDLLSVGDVVHVRRMTNDSDGSFIRWTLRQIPEVQGGFMAMDVHTGRVLAMQGGFSYQYSSFNRA TQATRQPGSSFKPFVYAAALDSGYGPNTIVIDAPIEVATGDGIWRPTNASNQFYGPSPLRTGIERSRNLMTVRLAQDVGM ETVARYAERFGVYDDMQPFLANALGSQETTLFRMVAAYAMFANGGERVEPTLVDRIQNRYGETVYRHDQRLCPDCGEAEI EAGLAPRIVSTRERVIDPITAYQLTSMMRGVVQRGTASGSVNLPVPTAGKTGTTNDARDVWFVGFTSNIVAGCYIGYDQP ESLGRGASGGGMCGPVFQRFMLEAIEEYGSGDFPVPEGGAFYPIDRYSGARLPSGASGENVVYELFRAGEAPFEGLLSVI DGGWAMSSDIPMFSQEGGDGGGGGQGTVVETSDGDAARVPTNTGFGTLSSGGLY
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=873, Percent_Identity=30.0114547537228, Blast_Score=365, Evalue=1e-102, Organism=Escherichia coli, GI1786343, Length=251, Percent_Identity=34.6613545816733, Blast_Score=122, Evalue=1e-28, Organism=Escherichia coli, GI1789601, Length=167, Percent_Identity=37.125748502994, Blast_Score=99, Evalue=1e-21, Organism=Escherichia coli, GI1788867, Length=171, Percent_Identity=36.2573099415205, Blast_Score=97, Evalue=5e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 93312; Mature: 93312
Theoretical pI: Translated: 4.53; Mature: 4.53
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRFIVGFFGAIFSAVTLGLVFAALGVGGLLFTYSRGLPDHEALSQYAPPTISRIYSRQGM CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCC IVDEFATERRLFTPAEEIPDLVSFAFVSAEDRNFYTHSGYDPRAIVAAFVDAVRSRGQDV CHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCC RGASTITQQVMKNFLLDSSRTVERKVREIILAARIERTLSKDRILELYLNEIFLGQNSYG CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC VTAAAQTYFNATLEDLTLEQVAYLAALPQAPSRFHPVNDYERAVGRRDYVLREMYENGYV CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCE TLEEMEAAQAMPLETVQGGHIEGRRLTRPPRNYFTDEIRRQLSAQYGADEFFSGGYAVRS EHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHH TMDESLQEVAEASLRRALERYDRNLGTWRGAADTIEPGLLTEEASWRDALRGAEIARDVD HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH GWFAAVVLEVGDSSARIGIEGVEDDDDGHFIPAEDVTWARPLLEDGSRGSTARVAGDLLS HHHHHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHHCCCCCCHHHHHHHHHH VGDVVHVRRMTNDSDGSFIRWTLRQIPEVQGGFMAMDVHTGRVLAMQGGFSYQYSSFNRA HHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHH TQATRQPGSSFKPFVYAAALDSGYGPNTIVIDAPIEVATGDGIWRPTNASNQFYGPSPLR HHHHHCCCCCCCCEEEEEECCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCHHH TGIERSRNLMTVRLAQDVGMETVARYAERFGVYDDMQPFLANALGSQETTLFRMVAAYAM HHHHHCCCEEEEEEHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH FANGGERVEPTLVDRIQNRYGETVYRHDQRLCPDCGEAEIEAGLAPRIVSTRERVIDPIT HHCCCCCCCHHHHHHHHHHHCCHHHHHCHHCCCCCCCHHHHCCCCCHHHHHHHHHHCHHH AYQLTSMMRGVVQRGTASGSVNLPVPTAGKTGTTNDARDVWFVGFTSNIVAGCYIGYDQP HHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHEEEEECCCCH ESLGRGASGGGMCGPVFQRFMLEAIEEYGSGDFPVPEGGAFYPIDRYSGARLPSGASGEN HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH VVYELFRAGEAPFEGLLSVIDGGWAMSSDIPMFSQEGGDGGGGGQGTVVETSDGDAARVP HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCEEECCCCCCEECC TNTGFGTLSSGGLY CCCCCCCCCCCCCC >Mature Secondary Structure MRFIVGFFGAIFSAVTLGLVFAALGVGGLLFTYSRGLPDHEALSQYAPPTISRIYSRQGM CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCC IVDEFATERRLFTPAEEIPDLVSFAFVSAEDRNFYTHSGYDPRAIVAAFVDAVRSRGQDV CHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCC RGASTITQQVMKNFLLDSSRTVERKVREIILAARIERTLSKDRILELYLNEIFLGQNSYG CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC VTAAAQTYFNATLEDLTLEQVAYLAALPQAPSRFHPVNDYERAVGRRDYVLREMYENGYV CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHCCCE TLEEMEAAQAMPLETVQGGHIEGRRLTRPPRNYFTDEIRRQLSAQYGADEFFSGGYAVRS EHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHH TMDESLQEVAEASLRRALERYDRNLGTWRGAADTIEPGLLTEEASWRDALRGAEIARDVD HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH GWFAAVVLEVGDSSARIGIEGVEDDDDGHFIPAEDVTWARPLLEDGSRGSTARVAGDLLS HHHHHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHHCCCCCCHHHHHHHHHH VGDVVHVRRMTNDSDGSFIRWTLRQIPEVQGGFMAMDVHTGRVLAMQGGFSYQYSSFNRA HHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHH TQATRQPGSSFKPFVYAAALDSGYGPNTIVIDAPIEVATGDGIWRPTNASNQFYGPSPLR HHHHHCCCCCCCCEEEEEECCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCHHH TGIERSRNLMTVRLAQDVGMETVARYAERFGVYDDMQPFLANALGSQETTLFRMVAAYAM HHHHHCCCEEEEEEHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH FANGGERVEPTLVDRIQNRYGETVYRHDQRLCPDCGEAEIEAGLAPRIVSTRERVIDPIT HHCCCCCCCHHHHHHHHHHHCCHHHHHCHHCCCCCCCHHHHCCCCCHHHHHHHHHHCHHH AYQLTSMMRGVVQRGTASGSVNLPVPTAGKTGTTNDARDVWFVGFTSNIVAGCYIGYDQP HHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHEEEEECCCCH ESLGRGASGGGMCGPVFQRFMLEAIEEYGSGDFPVPEGGAFYPIDRYSGARLPSGASGEN HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH VVYELFRAGEAPFEGLLSVIDGGWAMSSDIPMFSQEGGDGGGGGQGTVVETSDGDAARVP HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCEEECCCCCCEECC TNTGFGTLSSGGLY CCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9823893 [H]