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The map label for this gene is ctrA [H]

Identifier: 89054996

GI number: 89054996

Start: 2505518

End: 2506234

Strand: Reverse

Name: ctrA [H]

Synonym: Jann_2505

Alternate gene names: 89054996

Gene position: 2506234-2505518 (Counterclockwise)

Preceding gene: 89054997

Following gene: 89054995

Centisome position: 58.04

GC content: 56.35

Gene sequence:

>717_bases
ATGCGCGTACTGTTAGTCGAAGACGATCCCACCACGTCACGAAGCATTGAAATGATGCTCAAGCACGCGAACCTCAACGT
TTATTCCACCGATCTGGGGGAGGAGGGGATGGATCTCGCAAAACTCTACGACTACGACATCATCCTTCTCGACCTTAATC
TTCCCGATGTCTCCGGCCATGAGGTGCTGCGTCACTTGCGGACAGCCCGCGTTGATACGCCGATCCTGATCCTCTCTGGC
CTCGATGACCCGGAGAACAAGCTGAAAGGGTTCGGATTTGGGGCCGACGATTATCTGACCAAACCGTTCCACCGCGAAGA
ACTTGTGGCCCGCATTCACGCCATCATCCGTCGCTCCAAGGGGCACGCTCAGTCGGTCATCGATACCGGGCGAATTTCGG
TTAACCTGGATGCCAAGACCGTCGATGTGGCAGGAACGCCCGTGCATCTGACCGGCAAGGAATACCAGATGCTGGAACTG
CTATCGCTGCGCAAGGGCACGACGCTGACGAAAGAGATGTTCCTCAATCATTTGTATGGCGGCATGGACGAGCCCGAGTT
GAAGATCATCGACGTCTTCATCTGCAAACTGCGCAAAAAGCTGTCTGAGGCAACGGGCGGCGACACCTATATCGAGACGG
TTTGGGGCCGCGGCTACGTGCTTCGTGACCCGGTCTCGGCGGCGGATATGGACATGGATATGGTTGCCACGGGGTAA

Upstream 100 bases:

>100_bases
ATTGATGTTTTTGCGAAATCTATTGGTGCAGGTAACTTGGTGTTAACCATTTGGGCTAAAACTAGCAGCAACGAATGAGA
ACCACCTGGAGAACAAGCGG

Downstream 100 bases:

>100_bases
TCGCTCCCAACTTCCAATCCAACCTTTGCGTCCGGAATTTCCTTTGAAGCGGGGGCTTTCAATTGGATGTGTCCACGATG
ATGCAAAGAACGGCCCGGTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRVLLVEDDPTTSRSIEMMLKHANLNVYSTDLGEEGMDLAKLYDYDIILLDLNLPDVSGHEVLRHLRTARVDTPILILSG
LDDPENKLKGFGFGADDYLTKPFHREELVARIHAIIRRSKGHAQSVIDTGRISVNLDAKTVDVAGTPVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLSEATGGDTYIETVWGRGYVLRDPVSAADMDMDMVATG

Sequences:

>Translated_238_residues
MRVLLVEDDPTTSRSIEMMLKHANLNVYSTDLGEEGMDLAKLYDYDIILLDLNLPDVSGHEVLRHLRTARVDTPILILSG
LDDPENKLKGFGFGADDYLTKPFHREELVARIHAIIRRSKGHAQSVIDTGRISVNLDAKTVDVAGTPVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLSEATGGDTYIETVWGRGYVLRDPVSAADMDMDMVATG
>Mature_238_residues
MRVLLVEDDPTTSRSIEMMLKHANLNVYSTDLGEEGMDLAKLYDYDIILLDLNLPDVSGHEVLRHLRTARVDTPILILSG
LDDPENKLKGFGFGADDYLTKPFHREELVARIHAIIRRSKGHAQSVIDTGRISVNLDAKTVDVAGTPVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLSEATGGDTYIETVWGRGYVLRDPVSAADMDMDMVATG

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.5555555555556, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.9366515837104, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.9285714285714, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=35.6521739130435, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=31.8181818181818, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.2217194570136, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.9559471365639, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=32.15859030837, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.1801801801802, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.7180616740088, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=31.9148936170213, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=23.4513274336283, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=24.6808510638298, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26616; Mature: 26616

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDDPTTSRSIEMMLKHANLNVYSTDLGEEGMDLAKLYDYDIILLDLNLPDVSGH
CEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCEEEEEEECCCCCCHH
EVLRHLRTARVDTPILILSGLDDPENKLKGFGFGADDYLTKPFHREELVARIHAIIRRSK
HHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
GHAQSVIDTGRISVNLDAKTVDVAGTPVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHHHHCCEEEEEECCEEEEECCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLSEATGGDTYIETVWGRGYVLRDPVSAADMDMDMVATG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCEEEECC
>Mature Secondary Structure
MRVLLVEDDPTTSRSIEMMLKHANLNVYSTDLGEEGMDLAKLYDYDIILLDLNLPDVSGH
CEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCEEEEEEECCCCCCHH
EVLRHLRTARVDTPILILSGLDDPENKLKGFGFGADDYLTKPFHREELVARIHAIIRRSK
HHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
GHAQSVIDTGRISVNLDAKTVDVAGTPVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHHHHCCEEEEEECCEEEEECCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLSEATGGDTYIETVWGRGYVLRDPVSAADMDMDMVATG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA