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The map label for this gene is cdsA [H]

Identifier: 89054947

GI number: 89054947

Start: 2450200

End: 2451051

Strand: Reverse

Name: cdsA [H]

Synonym: Jann_2456

Alternate gene names: 89054947

Gene position: 2451051-2450200 (Counterclockwise)

Preceding gene: 89054948

Following gene: 89054946

Centisome position: 56.76

GC content: 64.08

Gene sequence:

>852_bases
ATGGCTGCGGGTCCCAAAACAGCATCTGGCCCGAAATTCGCGGATCTGCTTCCGCGCATCGCGTCCGCCTTTGTGTTGCT
GAGCGTTGCGGGCCTTGGCTTGTGGCTTGGCGGGATCGTTCTGGCGGTGTTGCTGTCGATTTTCGGGGCGGTCATGGTAT
GGGAATACTTTCGCCTCATCATCCGGCTCTCGTCGCCCGTGGCCCTTGTGTGCACCATCCTCAGTTCTGCGCTTCTGGCG
GTCTCGCTGCTGCTGGAGCACTCGTTGGTCGTGCCCGCCGACGGGGTGCTGGCGGTCTCTCCGGTCGCGGTCGGCGTGAT
GGTCCTGTCGATGATCGCCACCGCCGCGCCCGTCCACAAAAGCCGGTTGGAGACGCTTTTTGGCGCGATGATCCCGCTGG
CGACGTTCCTCTTCTTCTATCTCCACCAATCCGTGCCGCTGGTGATGTGGGTGGTTGTGGCGGTGGTGATTTCCACCGAC
GTCTCGGGCTATTTCTTCGGCAAGCTATTGGGCGGGCCGAAGTTCTGGCCGAGCCTGAGCCCCAACAAGACATGGTCCGG
CACGGCGTCCGGCTGGGTGATGGCCGCGCTGATCGCCGTGGGGTTAAGCGTCTACGCCTCGGACCCGATGCCCACGATGG
TGGTTGCGATCGTGTTTTTGGTGGCTGTGGCCTTCGCCGCGCAGATGGCCGATATCGCGGAATCGGCGCTGAAACGCAGG
GCGGGGGTCAAGGACAGCTCCAACCTGCTGCCCGGCCACGGCGGCGCACTGGACCGGTTTGACGGCATGCTTGGCGCCTT
CACCGTGGCGGGCCTGATGTTCGTGCTGGCGGGCTACACGGTGGTGTCGTGA

Upstream 100 bases:

>100_bases
CGCTCTGGCCTGATTTCACGGCGGACGTCTTCGCCAGTGTTCTTGGCCGCTTTGGCGCGCGCGACCGTCGTTTCGGCGCT
GTGAAAGCCTAAGCGCCGCC

Downstream 100 bases:

>100_bases
GCCCCCGGCCCGAGAAGCGGCGGGTCAGCATTTTCGGGGCCACCGGCTCCATCGGCCAGAACACCATTGATCTGATCGCC
CGCGCGCCGGAGGCCTATGA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAAGPKTASGPKFADLLPRIASAFVLLSVAGLGLWLGGIVLAVLLSIFGAVMVWEYFRLIIRLSSPVALVCTILSSALLA
VSLLLEHSLVVPADGVLAVSPVAVGVMVLSMIATAAPVHKSRLETLFGAMIPLATFLFFYLHQSVPLVMWVVVAVVISTD
VSGYFFGKLLGGPKFWPSLSPNKTWSGTASGWVMAALIAVGLSVYASDPMPTMVVAIVFLVAVAFAAQMADIAESALKRR
AGVKDSSNLLPGHGGALDRFDGMLGAFTVAGLMFVLAGYTVVS

Sequences:

>Translated_283_residues
MAAGPKTASGPKFADLLPRIASAFVLLSVAGLGLWLGGIVLAVLLSIFGAVMVWEYFRLIIRLSSPVALVCTILSSALLA
VSLLLEHSLVVPADGVLAVSPVAVGVMVLSMIATAAPVHKSRLETLFGAMIPLATFLFFYLHQSVPLVMWVVVAVVISTD
VSGYFFGKLLGGPKFWPSLSPNKTWSGTASGWVMAALIAVGLSVYASDPMPTMVVAIVFLVAVAFAAQMADIAESALKRR
AGVKDSSNLLPGHGGALDRFDGMLGAFTVAGLMFVLAGYTVVS
>Mature_282_residues
AAGPKTASGPKFADLLPRIASAFVLLSVAGLGLWLGGIVLAVLLSIFGAVMVWEYFRLIIRLSSPVALVCTILSSALLAV
SLLLEHSLVVPADGVLAVSPVAVGVMVLSMIATAAPVHKSRLETLFGAMIPLATFLFFYLHQSVPLVMWVVVAVVISTDV
SGYFFGKLLGGPKFWPSLSPNKTWSGTASGWVMAALIAVGLSVYASDPMPTMVVAIVFLVAVAFAAQMADIAESALKRRA
GVKDSSNLLPGHGGALDRFDGMLGAFTVAGLMFVLAGYTVVS

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=151, Percent_Identity=37.0860927152318, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787677, Length=110, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29468; Mature: 29336

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAGPKTASGPKFADLLPRIASAFVLLSVAGLGLWLGGIVLAVLLSIFGAVMVWEYFRLI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLSSPVALVCTILSSALLAVSLLLEHSLVVPADGVLAVSPVAVGVMVLSMIATAAPVHK
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SRLETLFGAMIPLATFLFFYLHQSVPLVMWVVVAVVISTDVSGYFFGKLLGGPKFWPSLS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC
PNKTWSGTASGWVMAALIAVGLSVYASDPMPTMVVAIVFLVAVAFAAQMADIAESALKRR
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVKDSSNLLPGHGGALDRFDGMLGAFTVAGLMFVLAGYTVVS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]