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The map label for this gene is ccdA [H]

Identifier: 89054889

GI number: 89054889

Start: 2399538

End: 2400293

Strand: Reverse

Name: ccdA [H]

Synonym: Jann_2398

Alternate gene names: 89054889

Gene position: 2400293-2399538 (Counterclockwise)

Preceding gene: 89054891

Following gene: 89054888

Centisome position: 55.59

GC content: 61.38

Gene sequence:

>756_bases
ATGTTTGGAATTGACCTCTTTGATGCATCGCTTTTGCCCGCGATGCTGGTGGCGCTCGCGGCGGGTGTGCTGAGCTTCCT
CAGCCCCTGCGTGTTGCCCATTGTGCCGCCATACCTCGCCTATATGGGCGGGATCACCATGAGCGATATCGAGGGGGAGG
CGCGCGCGGCGCGGCGCAAGGCGATCATGCCTGCGTTGTTTTTCGTGATGGGCCTGTCGACGGTCTTTATCTTTCTGGGC
TTCACGGCCTCGGTTCTGGGGCAGTTTTTCCTTCAAAATCAGATCCTTCTGGCGCGTATTTCAGGTGCTGTCGTGATCAT
ATTCGGCCTGCATTTTCTGGGCTTTATTCGTATTCCCTTGCTGGACCGCGAGGCGCGGCTGGATGCGGGCGATAAGGGCG
GATCGACCCTTGGGGCCTACGTTCTGGGCCTGGCGTTTGCGTTTGGCTGGACGCCCTGCATCGGCCCGCAACTGGGCGCG
ATCCTGTCGATTGCGGCGCAGGAAAGCTCGGTCCAGCGGGGCACGATGCTGCTTGGTGTCTATGCCGTCGGCCTGGGCCT
GCCGTTCCTGCTGGCCGCCGCCTTCATCGACCGGGCGCAAGGGCTGATGGGGTGCATGAAGCGGCATATGAAACTGATCG
AGCGGGTGATGGGTGTACTACTGGTAGCCGTTGGTGTGGCGCTGATGACTGGCGCGTTCTCCGCCTTTGCCTTCTGGCTG
CTGGAGACCTTCCCCGCGCTGGGTCAATTGGGCTGA

Upstream 100 bases:

>100_bases
GCAGATAGGGGGCGGACGCGGGCGCGTCCATTGAAATTGGCACGCGAATGTGACCGATTGGCCCCGTGACGGGGTGGTTA
GGGCGGCGTAAGGGTGGGAC

Downstream 100 bases:

>100_bases
CGTCACACCTTGGTGTGTCTGGCCCTTCCGCTACCAAAATCCGTGGCTATGCTGCGCCCATGACGCAGGTGTCCCGCAGA
CATGTCCTTTATATCCCCGG

Product: cytochrome c biogenesis protein, transmembrane protein

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MFGIDLFDASLLPAMLVALAAGVLSFLSPCVLPIVPPYLAYMGGITMSDIEGEARAARRKAIMPALFFVMGLSTVFIFLG
FTASVLGQFFLQNQILLARISGAVVIIFGLHFLGFIRIPLLDREARLDAGDKGGSTLGAYVLGLAFAFGWTPCIGPQLGA
ILSIAAQESSVQRGTMLLGVYAVGLGLPFLLAAAFIDRAQGLMGCMKRHMKLIERVMGVLLVAVGVALMTGAFSAFAFWL
LETFPALGQLG

Sequences:

>Translated_251_residues
MFGIDLFDASLLPAMLVALAAGVLSFLSPCVLPIVPPYLAYMGGITMSDIEGEARAARRKAIMPALFFVMGLSTVFIFLG
FTASVLGQFFLQNQILLARISGAVVIIFGLHFLGFIRIPLLDREARLDAGDKGGSTLGAYVLGLAFAFGWTPCIGPQLGA
ILSIAAQESSVQRGTMLLGVYAVGLGLPFLLAAAFIDRAQGLMGCMKRHMKLIERVMGVLLVAVGVALMTGAFSAFAFWL
LETFPALGQLG
>Mature_251_residues
MFGIDLFDASLLPAMLVALAAGVLSFLSPCVLPIVPPYLAYMGGITMSDIEGEARAARRKAIMPALFFVMGLSTVFIFLG
FTASVLGQFFLQNQILLARISGAVVIIFGLHFLGFIRIPLLDREARLDAGDKGGSTLGAYVLGLAFAFGWTPCIGPQLGA
ILSIAAQESSVQRGTMLLGVYAVGLGLPFLLAAAFIDRAQGLMGCMKRHMKLIERVMGVLLVAVGVALMTGAFSAFAFWL
LETFPALGQLG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 26569; Mature: 26569

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]