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The map label for this gene is mcpA [H]

Identifier: 89054860

GI number: 89054860

Start: 2373199

End: 2374785

Strand: Reverse

Name: mcpA [H]

Synonym: Jann_2369

Alternate gene names: 89054860

Gene position: 2374785-2373199 (Counterclockwise)

Preceding gene: 89054861

Following gene: 89054857

Centisome position: 55.0

GC content: 62.38

Gene sequence:

>1587_bases
ATGTTTAGATCGCGGGACTGGTCCGATGACCGGGCGATGGAGATGCGCCACGCGCGCAACTTGACCGTTGCGATGGTGGG
TGTTGTGACCCTAACCGGGGTCGTGCTTGGCGCGGCAGTTCTGCCTCTGGCCATGATTTCGCTGGCGCTTGCGGTGTCTG
CGATCCTCGCGGCGCGGGTGGGGGGGCAGATTGGGGCGCTCATCCTCGGCATCGCCCTTGTCGGGCAAGCGATTGTCTTT
ACCGCGACATTTGCCGGGCATCCTTGGCAGATCGACAGCCACATGTTATTTTTCGTGGTGCTCGCCGTCGGTGCCGTGAT
GCGCTCAATCCCCGCACTCTTTGCCATGACGGTCATGACCGCGGTTCATCACCTGGGATTTGGCGTTTTGATACCGGCAC
TGGTCTTTCCGAGTGTCAATCTGATCGAGAATGTGGAGCGGGTCGCCTTTCATGCGGTGATCGTGATTTTGGAAGTCAGT
TTCCTGACGATGTCGATACTGTCGCAGGACCGTAAGGACGCGGCCAAACAGGCTGCGCAACAGGAGGCGACGGAGGCCAC
GACGCGGGCAGAGCTGGCAGCCACGGAAGCGCAGTCCCTGCGCGCTGAGGCGGAAACAGCCAGTGCAGCGGCACGCAATG
TTACTGCGATGCTCGAACGCAATCTTCACGCCATGGCCTCCCGTGACCTGCGGGCGCGGATGGACGGCGATCCGGGGGCG
GAGTTCCGACAGATGTCCGCCGACTACAACCAGGCTGTCGGCAACGTCTCTCGGACGCTCGCGGGAGCGAAGACGATGGT
CCGCGATGTGGAGGCCGAGGCCGCCGCTTCAGCAGAGATGACCGTCAGCATGGCGTCTGAGCTGGAGCGTCAGGCTGTCG
AGGTTACCGGGGCCGCACGGTCGATACGCACGCTGTCTGAGTCGTTGGACACGACGGTGGGCGACATTCTCTCTGTTCGC
GATCAAGCTCAGATCGCCGCTAGCAAGGCCACTGAGGGGGGCGCGATTGTCCGCGATGCAGTCGATGCAATGGCGCAGAT
CACCGCCTCGTCGACCGAAATCGAGAAGATCATCCAGGTGATTGAAGAAATTTCGTTTCAAACCAACCTGCTGGCCTTGA
ACGCCGGTGTGGAGGCGGCCCGTGCGGGGCAGGCCGGTGCCGGGTTCGCGGTTGTCGCCTCGGAAGTGCGGGCCCTGTCA
CATCGCACCTCTGAGGCCGCCAATCAGGTCAAAACGCTGATTTCGGCCAGCTCGTCCCAGGTTGCGGCGGGCGCCGATAT
GGTCGACCGCGCCGGTGTTGCCCTTGATGAGATCGAGCGCTCCATCGAGGATGCCAGCGGCCGGGTCGCGGACATCTCCG
AACGGGCAACCGAGCAATCGAGTGCCGTCCAGGATGTTTCGGGTAGCTTGGCGCAGATCGACACGGTGATCCAGTCATTC
GCAACGCGAACTGAGGAAATCTCGGCCATCGGGGCGCGTGTGGTGGCCGATGCGGAGCGTCTGCATGGACTATTGGGCGA
GTTTATCATCATCGATGATACCGACGATGCATGGTCGGCTGATGGACCGCCGCAGGTGGCCGCCTGA

Upstream 100 bases:

>100_bases
CCCGCAGCCCGCGCGCTCGGGGCGTGGCTGATCCTGGACGGACGATTGATGGCAGCAATCTGCGGCGCCTCGCGCGCGGA
TTTGTCGGGAGGGTCGCACG

Downstream 100 bases:

>100_bases
CGCGCTGTGGTTTCTGTGCAGCGCGGAATGGTAGACGCGCTTCCGCGATGTGGCGGCTAGGGTCAGAGCTGTCCGAAACC
CAACCGCAGCCGGTCTGATC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MFRSRDWSDDRAMEMRHARNLTVAMVGVVTLTGVVLGAAVLPLAMISLALAVSAILAARVGGQIGALILGIALVGQAIVF
TATFAGHPWQIDSHMLFFVVLAVGAVMRSIPALFAMTVMTAVHHLGFGVLIPALVFPSVNLIENVERVAFHAVIVILEVS
FLTMSILSQDRKDAAKQAAQQEATEATTRAELAATEAQSLRAEAETASAAARNVTAMLERNLHAMASRDLRARMDGDPGA
EFRQMSADYNQAVGNVSRTLAGAKTMVRDVEAEAAASAEMTVSMASELERQAVEVTGAARSIRTLSESLDTTVGDILSVR
DQAQIAASKATEGGAIVRDAVDAMAQITASSTEIEKIIQVIEEISFQTNLLALNAGVEAARAGQAGAGFAVVASEVRALS
HRTSEAANQVKTLISASSSQVAAGADMVDRAGVALDEIERSIEDASGRVADISERATEQSSAVQDVSGSLAQIDTVIQSF
ATRTEEISAIGARVVADAERLHGLLGEFIIIDDTDDAWSADGPPQVAA

Sequences:

>Translated_528_residues
MFRSRDWSDDRAMEMRHARNLTVAMVGVVTLTGVVLGAAVLPLAMISLALAVSAILAARVGGQIGALILGIALVGQAIVF
TATFAGHPWQIDSHMLFFVVLAVGAVMRSIPALFAMTVMTAVHHLGFGVLIPALVFPSVNLIENVERVAFHAVIVILEVS
FLTMSILSQDRKDAAKQAAQQEATEATTRAELAATEAQSLRAEAETASAAARNVTAMLERNLHAMASRDLRARMDGDPGA
EFRQMSADYNQAVGNVSRTLAGAKTMVRDVEAEAAASAEMTVSMASELERQAVEVTGAARSIRTLSESLDTTVGDILSVR
DQAQIAASKATEGGAIVRDAVDAMAQITASSTEIEKIIQVIEEISFQTNLLALNAGVEAARAGQAGAGFAVVASEVRALS
HRTSEAANQVKTLISASSSQVAAGADMVDRAGVALDEIERSIEDASGRVADISERATEQSSAVQDVSGSLAQIDTVIQSF
ATRTEEISAIGARVVADAERLHGLLGEFIIIDDTDDAWSADGPPQVAA
>Mature_528_residues
MFRSRDWSDDRAMEMRHARNLTVAMVGVVTLTGVVLGAAVLPLAMISLALAVSAILAARVGGQIGALILGIALVGQAIVF
TATFAGHPWQIDSHMLFFVVLAVGAVMRSIPALFAMTVMTAVHHLGFGVLIPALVFPSVNLIENVERVAFHAVIVILEVS
FLTMSILSQDRKDAAKQAAQQEATEATTRAELAATEAQSLRAEAETASAAARNVTAMLERNLHAMASRDLRARMDGDPGA
EFRQMSADYNQAVGNVSRTLAGAKTMVRDVEAEAAASAEMTVSMASELERQAVEVTGAARSIRTLSESLDTTVGDILSVR
DQAQIAASKATEGGAIVRDAVDAMAQITASSTEIEKIIQVIEEISFQTNLLALNAGVEAARAGQAGAGFAVVASEVRALS
HRTSEAANQVKTLISASSSQVAAGADMVDRAGVALDEIERSIEDASGRVADISERATEQSSAVQDVSGSLAQIDTVIQSF
ATRTEEISAIGARVVADAERLHGLLGEFIIIDDTDDAWSADGPPQVAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=260, Percent_Identity=35.7692307692308, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788195, Length=239, Percent_Identity=35.9832635983264, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI2367378, Length=257, Percent_Identity=33.0739299610895, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788194, Length=227, Percent_Identity=34.3612334801762, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1789453, Length=182, Percent_Identity=37.9120879120879, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 55316; Mature: 55316

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSRDWSDDRAMEMRHARNLTVAMVGVVTLTGVVLGAAVLPLAMISLALAVSAILAARV
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGQIGALILGIALVGQAIVFTATFAGHPWQIDSHMLFFVVLAVGAVMRSIPALFAMTVMT
CCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVHHLGFGVLIPALVFPSVNLIENVERVAFHAVIVILEVSFLTMSILSQDRKDAAKQAAQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEATEATTRAELAATEAQSLRAEAETASAAARNVTAMLERNLHAMASRDLRARMDGDPGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EFRQMSADYNQAVGNVSRTLAGAKTMVRDVEAEAAASAEMTVSMASELERQAVEVTGAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIRTLSESLDTTVGDILSVRDQAQIAASKATEGGAIVRDAVDAMAQITASSTEIEKIIQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
IEEISFQTNLLALNAGVEAARAGQAGAGFAVVASEVRALSHRTSEAANQVKTLISASSSQ
HHHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAAGADMVDRAGVALDEIERSIEDASGRVADISERATEQSSAVQDVSGSLAQIDTVIQSF
HHCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ATRTEEISAIGARVVADAERLHGLLGEFIIIDDTDDAWSADGPPQVAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFRSRDWSDDRAMEMRHARNLTVAMVGVVTLTGVVLGAAVLPLAMISLALAVSAILAARV
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGQIGALILGIALVGQAIVFTATFAGHPWQIDSHMLFFVVLAVGAVMRSIPALFAMTVMT
CCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVHHLGFGVLIPALVFPSVNLIENVERVAFHAVIVILEVSFLTMSILSQDRKDAAKQAAQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEATEATTRAELAATEAQSLRAEAETASAAARNVTAMLERNLHAMASRDLRARMDGDPGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EFRQMSADYNQAVGNVSRTLAGAKTMVRDVEAEAAASAEMTVSMASELERQAVEVTGAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIRTLSESLDTTVGDILSVRDQAQIAASKATEGGAIVRDAVDAMAQITASSTEIEKIIQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
IEEISFQTNLLALNAGVEAARAGQAGAGFAVVASEVRALSHRTSEAANQVKTLISASSSQ
HHHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAAGADMVDRAGVALDEIERSIEDASGRVADISERATEQSSAVQDVSGSLAQIDTVIQSF
HHCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ATRTEEISAIGARVVADAERLHGLLGEFIIIDDTDDAWSADGPPQVAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]