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The map label for this gene is yodT [H]

Identifier: 89054819

GI number: 89054819

Start: 2334487

End: 2335821

Strand: Reverse

Name: yodT [H]

Synonym: Jann_2328

Alternate gene names: 89054819

Gene position: 2335821-2334487 (Counterclockwise)

Preceding gene: 89054820

Following gene: 89054814

Centisome position: 54.1

GC content: 64.79

Gene sequence:

>1335_bases
GTGACGCAAACGCCCGGGACCCACGTCTTCGGGCGGTCAAACGCCACCCTTCGGCGGGCCGTTTCGGGGGAGGGTTGCTA
CATCATCGACGCGGATGGCACCCGTTTTCTTGATGGCTGTTGCGGGGCGGCGGTCTCCTGCCTTGGCCATTCCGACGCCA
GCGTGCGCGCCGCCATGCACGCCCAGATCGACGCGCTGGCCTATGCCCATACCGGATATTTCACCTCTGGCCCGGCGGAG
GATCTGGCCGATCTGCTGATCGACCACGCGCCGGACGGGATTGAGAAGGTCTATTTCCTCTCCGGCGGGTCGGAGGCGAT
GGAAACCGCCCTGAAACTCGCGCGCCAATATATGGTGGAGACGGGACAACCGGGCCGTCACAAGATCATCGCCCGGCGGC
AAAGCTATCATGGCAACACGCTCGGCGCTTTGGCCGTGGGTGGCAACGCGGCACGGCGCGAGAAGTACCAGCCGTTGTTG
GTGGAGACGTCCCATATCAGCCCGTGCTTTGAATACCGGGGCCGTGCCGACGATGAGAGCGCGTTTGACTACGGCCAGCG
CGTCGCCAATGAACTTGAAGCCGAGATCCAGCGCCTTGGCCCCGAAACGGTCATGGCCTTCGTGGCCGAACCCGTCGTGG
GGGCCACTGCCGGAGCCGTGCCGCCGGTGGACGGCTACTTCAAACGTATCCGCGAGATCTGCGACCAATACGGTATCCTG
TTGATCCTCGACGAAGTCATGTGCGGCATGGGCCGGACCGGCACCCTGTTCGCCTGCGAACAAGAGGGCATCACTCCCGA
CATCGTCGTCATCGCCAAGGGCCTCGGCGCGGGCTACGTGCCCATCGGCGCGATGCTGTGTTCCGGCACGATCTACAACA
CCATCTCCAAAGGGTCCGGCGCGTTTGAACATGGGCACACCTATCAGGCCCACCCGACCGCCGCCGCAGGCGCGCTGGCT
GTCGTCCGGGCCATGCTGGACCGAGACCTGATCCCCCGCGTGCGCGAACAGGGCGCAAAACTGGACGCCGCCTTGCAGGT
CGAGTTTGGCCAACACCCCCATGTGGGCGATATCCGGGGGCGGGGCCTCTTCCGCGCCATTGAACTGGTCGAAGATCGCG
CCACGAAAACCCCCTTCGATCCGGCCCGAAAACTGGGCACGGCAATCAAAGCGGCTGCGATGGAGGAGGGGCTGATGATC
TACCCCGGCAGCGGCACGGCGGACGGCATGCGCGGCGACCACATCCTCATTGCGCCGCCCTTCATCATCTCGGACGATCA
GATCGACGAGCTGACGCAGAAACTGTCCCGCGCCTTGACCCGCGTTCTCGCCTAA

Upstream 100 bases:

>100_bases
TGGGGGCCCATACGCCTGAAATCAGCGACTATCTTCTGGGTCCCAACGCCGCCCGCGTGGTCCGCCACGCCAAGCAATCG
GTCTTTGTGGTGCGGGGCAA

Downstream 100 bases:

>100_bases
GTCTCAGGGACGCGGCGTCAGCACCGTGATGCCCAGGTTCGCGGCCCGGGCCAGATCCGGGTCCAGGGTCATCGGCACAT
ATTCCCCGCGCCGCCACAGA

Product: hypothetical protein

Products: S-Adenosyl-4-methylthio-2-oxobutanoate; 7,8-Diaminononanoate [C]

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTQTPGTHVFGRSNATLRRAVSGEGCYIIDADGTRFLDGCCGAAVSCLGHSDASVRAAMHAQIDALAYAHTGYFTSGPAE
DLADLLIDHAPDGIEKVYFLSGGSEAMETALKLARQYMVETGQPGRHKIIARRQSYHGNTLGALAVGGNAARREKYQPLL
VETSHISPCFEYRGRADDESAFDYGQRVANELEAEIQRLGPETVMAFVAEPVVGATAGAVPPVDGYFKRIREICDQYGIL
LILDEVMCGMGRTGTLFACEQEGITPDIVVIAKGLGAGYVPIGAMLCSGTIYNTISKGSGAFEHGHTYQAHPTAAAGALA
VVRAMLDRDLIPRVREQGAKLDAALQVEFGQHPHVGDIRGRGLFRAIELVEDRATKTPFDPARKLGTAIKAAAMEEGLMI
YPGSGTADGMRGDHILIAPPFIISDDQIDELTQKLSRALTRVLA

Sequences:

>Translated_444_residues
MTQTPGTHVFGRSNATLRRAVSGEGCYIIDADGTRFLDGCCGAAVSCLGHSDASVRAAMHAQIDALAYAHTGYFTSGPAE
DLADLLIDHAPDGIEKVYFLSGGSEAMETALKLARQYMVETGQPGRHKIIARRQSYHGNTLGALAVGGNAARREKYQPLL
VETSHISPCFEYRGRADDESAFDYGQRVANELEAEIQRLGPETVMAFVAEPVVGATAGAVPPVDGYFKRIREICDQYGIL
LILDEVMCGMGRTGTLFACEQEGITPDIVVIAKGLGAGYVPIGAMLCSGTIYNTISKGSGAFEHGHTYQAHPTAAAGALA
VVRAMLDRDLIPRVREQGAKLDAALQVEFGQHPHVGDIRGRGLFRAIELVEDRATKTPFDPARKLGTAIKAAAMEEGLMI
YPGSGTADGMRGDHILIAPPFIISDDQIDELTQKLSRALTRVLA
>Mature_443_residues
TQTPGTHVFGRSNATLRRAVSGEGCYIIDADGTRFLDGCCGAAVSCLGHSDASVRAAMHAQIDALAYAHTGYFTSGPAED
LADLLIDHAPDGIEKVYFLSGGSEAMETALKLARQYMVETGQPGRHKIIARRQSYHGNTLGALAVGGNAARREKYQPLLV
ETSHISPCFEYRGRADDESAFDYGQRVANELEAEIQRLGPETVMAFVAEPVVGATAGAVPPVDGYFKRIREICDQYGILL
ILDEVMCGMGRTGTLFACEQEGITPDIVVIAKGLGAGYVPIGAMLCSGTIYNTISKGSGAFEHGHTYQAHPTAAAGALAV
VRAMLDRDLIPRVREQGAKLDAALQVEFGQHPHVGDIRGRGLFRAIELVEDRATKTPFDPARKLGTAIKAAAMEEGLMIY
PGSGTADGMRGDHILIAPPFIISDDQIDELTQKLSRALTRVLA

Specific function: Biotin biosynthesis. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=440, Percent_Identity=28.4090909090909, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI37574042, Length=442, Percent_Identity=28.2805429864253, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI226442705, Length=442, Percent_Identity=27.6018099547511, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI226442709, Length=399, Percent_Identity=28.3208020050125, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI284507298, Length=344, Percent_Identity=30.2325581395349, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=429, Percent_Identity=27.5058275058275, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=27.5395033860045, Blast_Score=129, Evalue=7e-30,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=31.7647058823529, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789759, Length=423, Percent_Identity=31.9148936170213, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI145693181, Length=413, Percent_Identity=29.0556900726392, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1789016, Length=419, Percent_Identity=30.7875894988067, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788044, Length=410, Percent_Identity=29.0243902439024, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787560, Length=426, Percent_Identity=28.8732394366197, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786349, Length=306, Percent_Identity=26.797385620915, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=29.8611111111111, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=425, Percent_Identity=27.0588235294118, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI32564660, Length=456, Percent_Identity=26.9736842105263, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=253, Percent_Identity=32.4110671936759, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=424, Percent_Identity=27.122641509434, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6323470, Length=423, Percent_Identity=26.241134751773, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324386, Length=455, Percent_Identity=23.5164835164835, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357415, Length=415, Percent_Identity=31.0843373493976, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI21356575, Length=444, Percent_Identity=27.9279279279279, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28574759, Length=440, Percent_Identity=27.0454545454545, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI161085790, Length=436, Percent_Identity=26.3761467889908, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI281366494, Length=386, Percent_Identity=24.6113989637306, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667139, Length=386, Percent_Identity=24.6113989637306, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667143, Length=386, Percent_Identity=24.6113989637306, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.62 [C]

Molecular weight: Translated: 47434; Mature: 47302

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTPGTHVFGRSNATLRRAVSGEGCYIIDADGTRFLDGCCGAAVSCLGHSDASVRAAMH
CCCCCCCCEECCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AQIDALAYAHTGYFTSGPAEDLADLLIDHAPDGIEKVYFLSGGSEAMETALKLARQYMVE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
TGQPGRHKIIARRQSYHGNTLGALAVGGNAARREKYQPLLVETSHISPCFEYRGRADDES
CCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
AFDYGQRVANELEAEIQRLGPETVMAFVAEPVVGATAGAVPPVDGYFKRIREICDQYGIL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHCCHH
LILDEVMCGMGRTGTLFACEQEGITPDIVVIAKGLGAGYVPIGAMLCSGTIYNTISKGSG
HHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHCCCCC
AFEHGHTYQAHPTAAAGALAVVRAMLDRDLIPRVREQGAKLDAALQVEFGQHPHVGDIRG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
RGLFRAIELVEDRATKTPFDPARKLGTAIKAAAMEEGLMIYPGSGTADGMRGDHILIAPP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECC
FIISDDQIDELTQKLSRALTRVLA
EEECCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TQTPGTHVFGRSNATLRRAVSGEGCYIIDADGTRFLDGCCGAAVSCLGHSDASVRAAMH
CCCCCCCEECCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AQIDALAYAHTGYFTSGPAEDLADLLIDHAPDGIEKVYFLSGGSEAMETALKLARQYMVE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
TGQPGRHKIIARRQSYHGNTLGALAVGGNAARREKYQPLLVETSHISPCFEYRGRADDES
CCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
AFDYGQRVANELEAEIQRLGPETVMAFVAEPVVGATAGAVPPVDGYFKRIREICDQYGIL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHCCHH
LILDEVMCGMGRTGTLFACEQEGITPDIVVIAKGLGAGYVPIGAMLCSGTIYNTISKGSG
HHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHCCCCC
AFEHGHTYQAHPTAAAGALAVVRAMLDRDLIPRVREQGAKLDAALQVEFGQHPHVGDIRG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
RGLFRAIELVEDRATKTPFDPARKLGTAIKAAAMEEGLMIYPGSGTADGMRGDHILIAPP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEECC
FIISDDQIDELTQKLSRALTRVLA
EEECCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Amino-7-oxononanoate; S-Adenosyl-L-methionine [C]

Specific reaction: 8-Amino-7-oxononanoate + S-Adenosyl-L-methionine <==> S-Adenosyl-4-methylthio-2-oxobutanoate + 7,8-Diaminononanoate [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]