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The map label for this gene is aroQ

Identifier: 89054791

GI number: 89054791

Start: 2305678

End: 2306124

Strand: Direct

Name: aroQ

Synonym: Jann_2300

Alternate gene names: 89054791

Gene position: 2305678-2306124 (Clockwise)

Preceding gene: 89054790

Following gene: 89054792

Centisome position: 53.4

GC content: 62.42

Gene sequence:

>447_bases
ATGAAGATATCTGTTTTCAACGGGCCGAACCTGAACGCTCTCGGGACCCGGGAGCCGGGCATTTACGGTGCCGATACCCT
GGCCGATATCGAGGCGGCCTGCCGCACCACCGCCGCTGATCTGGGCGTCGATCTTGATTTCCTGCAAACCAACCAAGAAG
GCGCGCTGGTCGATGCCTTCCACGCCGCGCGCGACACGTCAGATGGCGTGGTGATCAATGCGGGCGCCTATACCCACACC
TCCATCGCGTTGCGCGATGCGATCAGCGCTACCGAACTTCCCACGGTGGAGCTGCACCTATCCAACACCCACGCAAGGGA
GGCCTTTCGACATCATTCGATGATCGCGCCGGTCTGCGTGGGCCTCATCCTGGGCTTCGGCGCGTATGGCTACCCCCTCG
CCGTCACCGCGCTGGTCCAGCACCTCAAGCAAGGAAATGCGCCTTGA

Upstream 100 bases:

>100_bases
GGCATGCCAGAGCCGCGGTAGACACGGGCGGGCGGCTCCAACGACGACTCGACGCACGGACAGGTTTGAATATATGGTGC
GCCCAAAGGGATTTAGACGC

Downstream 100 bases:

>100_bases
AACATCTCCGCCCCTATCTGGAAATGACCACGGTCGAAGACCTGTGGTCCCACCACACGAAAACCCTCGCAAGTTACGGA
TTTGACCGCGTTTTCTATGG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKISVFNGPNLNALGTREPGIYGADTLADIEAACRTTAADLGVDLDFLQTNQEGALVDAFHAARDTSDGVVINAGAYTHT
SIALRDAISATELPTVELHLSNTHAREAFRHHSMIAPVCVGLILGFGAYGYPLAVTALVQHLKQGNAP

Sequences:

>Translated_148_residues
MKISVFNGPNLNALGTREPGIYGADTLADIEAACRTTAADLGVDLDFLQTNQEGALVDAFHAARDTSDGVVINAGAYTHT
SIALRDAISATELPTVELHLSNTHAREAFRHHSMIAPVCVGLILGFGAYGYPLAVTALVQHLKQGNAP
>Mature_148_residues
MKISVFNGPNLNALGTREPGIYGADTLADIEAACRTTAADLGVDLDFLQTNQEGALVDAFHAARDTSDGVVINAGAYTHT
SIALRDAISATELPTVELHLSNTHAREAFRHHSMIAPVCVGLILGFGAYGYPLAVTALVQHLKQGNAP

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_JANSC (Q28PZ5)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510242.1
- ProteinModelPortal:   Q28PZ5
- SMR:   Q28PZ5
- STRING:   Q28PZ5
- GeneID:   3934756
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2300
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   NTHAREA
- ProtClustDB:   PRK05395
- BioCyc:   JSP290400:JANN_2300-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15553; Mature: 15553

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVFNGPNLNALGTREPGIYGADTLADIEAACRTTAADLGVDLDFLQTNQEGALVDAF
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCHHHHH
HAARDTSDGVVINAGAYTHTSIALRDAISATELPTVELHLSNTHAREAFRHHSMIAPVCV
HHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
GLILGFGAYGYPLAVTALVQHLKQGNAP
HHHHHCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKISVFNGPNLNALGTREPGIYGADTLADIEAACRTTAADLGVDLDFLQTNQEGALVDAF
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCHHHHH
HAARDTSDGVVINAGAYTHTSIALRDAISATELPTVELHLSNTHAREAFRHHSMIAPVCV
HHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
GLILGFGAYGYPLAVTALVQHLKQGNAP
HHHHHCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA