BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

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The map label for this gene is gdhII [H]

Identifier: 89054762

GI number: 89054762

Start: 2277670

End: 2278413

Strand: Reverse

Name: gdhII [H]

Synonym: Jann_2271

Alternate gene names: 89054762

Gene position: 2278413-2277670 (Counterclockwise)

Preceding gene: 89054763

Following gene: 89054761

Centisome position: 52.77

GC content: 63.84

Gene sequence:

>744_bases
ATGAAAACCGCTTTGGTAACCGGCGGCAGCGGCGACATAGGCCGCGCCATTGGGCAAGTCCTGATCGACGATGGCTACCG
CGTGGGCCTGCTTGATCTGGATCAGGCAGACGTGAGGACTGCGGCTGAGGACCTAGGCGCAACGGGTCTGGTGGCCGATG
TGACGAACGAGTCCGATGTTGAGCGCGCGATTGCCGACTTCGGCGCGGTTCCGGACCTGGTGGTGAACAACGCAGGGATA
GGCCGGTTTGCCTCACTTCTGGACATGGAGATCGAGACGTTCCGCCGCCAGCTTGACGTCAACCTGACCGGCGCTTTCAT
CGTCGCTCGCGCGGCAGCCAAGGGAATGGTGGAACGTGGGTCCGGCGTCATCCTGAACATCACCTCCATCAACGCAATCA
CCACGGGGCCCGGCACCGGGTCCTATCCGGCAGCCAAGGCGGGCCTCGCAAAACTGACCGAGATGATGGCGTTGGAATGG
GGCCCACTGGGTGTGCGCGTCAACGCCATTGCACCGGGCTTTATCGATGCGGGTATCTCGACGCCGTTCTACGCTGATCC
GGCAGTGCGCGCCTCGCGCGGGGGGGCCGTGCCGTCGCGACGCTTGGGCGTGTCCGAGGATATTGCCAACGCCGTGTCCT
ACCTCGCCAGCGACAAGGCGAGTTACGTGAACGGGCACCACCTCGTGGTCGACGGTGGTGTCTCGGTCAGCTTGCTAACG
CAGCTGCCACGGGTCGCAACATGA

Upstream 100 bases:

>100_bases
CACGGCCGGACCCCACCGATCCCCCACAAATCTCCACCAAAACAGAACGGCCCAACTGGGGCCACTACCCGATCATCTTT
GATCCCAAGAAGGCATGGCG

Downstream 100 bases:

>100_bases
GCCCGCGGAGCCTCATTCTTTCGGGTGGCATCCTACATCCCTTTGACCAGACCTCCGACCTGATCGCGCAGCATCTCACA
TTACTAGGTATCCGGTCCGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKTALVTGGSGDIGRAIGQVLIDDGYRVGLLDLDQADVRTAAEDLGATGLVADVTNESDVERAIADFGAVPDLVVNNAGI
GRFASLLDMEIETFRRQLDVNLTGAFIVARAAAKGMVERGSGVILNITSINAITTGPGTGSYPAAKAGLAKLTEMMALEW
GPLGVRVNAIAPGFIDAGISTPFYADPAVRASRGGAVPSRRLGVSEDIANAVSYLASDKASYVNGHHLVVDGGVSVSLLT
QLPRVAT

Sequences:

>Translated_247_residues
MKTALVTGGSGDIGRAIGQVLIDDGYRVGLLDLDQADVRTAAEDLGATGLVADVTNESDVERAIADFGAVPDLVVNNAGI
GRFASLLDMEIETFRRQLDVNLTGAFIVARAAAKGMVERGSGVILNITSINAITTGPGTGSYPAAKAGLAKLTEMMALEW
GPLGVRVNAIAPGFIDAGISTPFYADPAVRASRGGAVPSRRLGVSEDIANAVSYLASDKASYVNGHHLVVDGGVSVSLLT
QLPRVAT
>Mature_247_residues
MKTALVTGGSGDIGRAIGQVLIDDGYRVGLLDLDQADVRTAAEDLGATGLVADVTNESDVERAIADFGAVPDLVVNNAGI
GRFASLLDMEIETFRRQLDVNLTGAFIVARAAAKGMVERGSGVILNITSINAITTGPGTGSYPAAKAGLAKLTEMMALEW
GPLGVRVNAIAPGFIDAGISTPFYADPAVRASRGGAVPSRRLGVSEDIANAVSYLASDKASYVNGHHLVVDGGVSVSLLT
QLPRVAT

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=35.1239669421488, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=32.5102880658436, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI7705925, Length=234, Percent_Identity=31.6239316239316, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=33.8709677419355, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=32.9317269076305, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.4573643410853, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=32.4110671936759, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=31.9502074688797, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=32.4022346368715, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI66933014, Length=224, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503301, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=34.4444444444444, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=28.0334728033473, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=38.0753138075314, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=33.7448559670782, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=33.0612244897959, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=32.8, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789208, Length=175, Percent_Identity=34.8571428571429, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=29.6747967479675, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=34.5098039215686, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=34.8360655737705, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.90625, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=31.3559322033898, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=28.1124497991968, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786701, Length=178, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=28.1938325991189, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=28.2786885245902, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=36.8852459016393, Blast_Score=126, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=36.25, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=30.2788844621514, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.8804780876494, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=28.8065843621399, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.8, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=30.2904564315353, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=29.7619047619048, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=29.5880149812734, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.4832713754647, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=28.6764705882353, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.4090909090909, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=29.1044776119403, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.9693486590038, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=28.4132841328413, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=27.0676691729323, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=28.3582089552239, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=29.1044776119403, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=27.6119402985075, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=27.7372262773723, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=26.6917293233083, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=27.4900398406374, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=27.1317829457364, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=26.4925373134328, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=212, Percent_Identity=29.7169811320755, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=28.740157480315, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.2172284644195, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.1698113207547, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=31.0160427807487, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=37.5510204081633, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=36.2139917695473, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=30.4878048780488, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=30.8333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=31.0483870967742, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=30.0395256916996, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=215, Percent_Identity=28.3720930232558, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=30.5555555555556, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641232, Length=249, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI116007236, Length=247, Percent_Identity=29.1497975708502, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 25364; Mature: 25364

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTALVTGGSGDIGRAIGQVLIDDGYRVGLLDLDQADVRTAAEDLGATGLVADVTNESDV
CCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHH
ERAIADFGAVPDLVVNNAGIGRFASLLDMEIETFRRQLDVNLTGAFIVARAAAKGMVERG
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
SGVILNITSINAITTGPGTGSYPAAKAGLAKLTEMMALEWGPLGVRVNAIAPGFIDAGIS
CCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCC
TPFYADPAVRASRGGAVPSRRLGVSEDIANAVSYLASDKASYVNGHHLVVDGGVSVSLLT
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCHHHHH
QLPRVAT
HCCCCCC
>Mature Secondary Structure
MKTALVTGGSGDIGRAIGQVLIDDGYRVGLLDLDQADVRTAAEDLGATGLVADVTNESDV
CCCEEEECCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHH
ERAIADFGAVPDLVVNNAGIGRFASLLDMEIETFRRQLDVNLTGAFIVARAAAKGMVERG
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
SGVILNITSINAITTGPGTGSYPAAKAGLAKLTEMMALEWGPLGVRVNAIAPGFIDAGIS
CCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCC
TPFYADPAVRASRGGAVPSRRLGVSEDIANAVSYLASDKASYVNGHHLVVDGGVSVSLLT
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCHHHHH
QLPRVAT
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA