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The map label for this gene is hflX [H]

Identifier: 89054736

GI number: 89054736

Start: 2252642

End: 2253949

Strand: Direct

Name: hflX [H]

Synonym: Jann_2245

Alternate gene names: 89054736

Gene position: 2252642-2253949 (Clockwise)

Preceding gene: 89054735

Following gene: 89054737

Centisome position: 52.17

GC content: 65.52

Gene sequence:

>1308_bases
GTGAGCGCGGGATTGCGCGCCACGGACGGGGATGATGAGGGTCTTGAAAAAGGCCCAATGCGGGCGCTTGTCTTGCATCC
GGACATCAAATCCGACCGCACCCGGCGTGATCCTGCCTTCGCGCTGGAGGAGGGCGTTGCCCTGGCTGCGGCATTGCCGG
ACCTGGAGGTCGTGGACGCACAGGTGGTGCGGTTGCCCCGGGCACAGCCGGGCCTGTTGTTCGGATCCGGCAAGATCCAG
GAACTGCACGATCTGATCGAAGCGCTCGATATCGGTCTCGTGCTGATTGACGGGCCCGTGACGCCGGTGCAGCAGCGCAA
CCTTGAAAGGGAATGGGGGTGCAAGCTGCTGGATCGCACCGGCCTGATCCTGGAGATTTTCGCCGACCGCGCCGCCACGC
GCGAGGGCGTCTTGCAGGTCGAACTGGCGGCTCTGTCCTATCAGCGCACGCGCCTTGTGCGGGCGTGGACCCACCTTGAA
CGGCAGCGCGGCGGTCTCGGCTTCGTGGGCGGCCCCGGGGAGACCCAGATCGAGGCCGACAGACGCGCCATTGACGAGGC
GGTCACCCGGATCAAGCGTCAACTCGCGAAGGTCGTGAAAACTCGGGCCCTGCATCGGTCTGCGCGCGCCAAGGTGCCCT
ATCCGATTGTGGCTCTGGTGGGCTACACGAACGCCGGGAAGTCCACGTTGTTCAACCGCTTGACCGGCGCGGACGTGATG
GCGAAGGACATGCTGTTCGCCACGCTCGATCCGACCATGCGCGCCGTCACGCTGCCCGATGGCACCGACGTGATCCTGTC
CGACACGGTGGGTTTCATCTCTGATCTGCCGACGCAATTGGTTGCCGCCTTCCGCGCCACGTTGGAAGAGGTGCTGGATG
CCGATCTGATCGTGCATGTTCGCGATATCAGCCACCCGCAAACCGTCGAACAGGCCGAAGATGTCCACGCCATCCTGGGC
GATCTGGGCGTGTCGGACCAGTCCGCGCAGCTGGAGGTCTGGAACAAGGTCGATTTGCTGGATGAGGCGGCGCAGACGGC
CCGGCAGGTGGAGGCCGACCGCAACGAGGCGATCTTTGCCACCTCGGCGCTGACCGGTGCGGGCATGGATGATTTTCTGA
CCGCCGTGTCGCACACCCTGTCGCCGCCGCGATTGGAGGCCGTCGTGGAGCTGCCCCATAGCGACGGCCGCAAACGCGCG
TGGCTGTTCGAGCAAGGCGTGGTGGAGCGCGAGGAGCCGACCGAGATCGGCACACAACTGACCGTCCTGTGGACCACGCG
CCAGCAAAAGGCGTTCCGCGCGCTCTGA

Upstream 100 bases:

>100_bases
GTGTTCTGCTGCGCCGCGATGGCCAGTCGCAACTTGTCTACAAGCACGCGATTTCCACCGTCATGCCAGCCCAACCCATC
AGCCTCTACGACGGGGAAGA

Downstream 100 bases:

>100_bases
GCCCAATCTGCCTGATCCCAATTCGTCTGATCCCAATTCGTCTGATCCCAGTCTGTCTGGCGGCAGCCCGCCAGGCTTCG
GGGATCGATGACAAATCTGA

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSAGLRATDGDDEGLEKGPMRALVLHPDIKSDRTRRDPAFALEEGVALAAALPDLEVVDAQVVRLPRAQPGLLFGSGKIQ
ELHDLIEALDIGLVLIDGPVTPVQQRNLEREWGCKLLDRTGLILEIFADRAATREGVLQVELAALSYQRTRLVRAWTHLE
RQRGGLGFVGGPGETQIEADRRAIDEAVTRIKRQLAKVVKTRALHRSARAKVPYPIVALVGYTNAGKSTLFNRLTGADVM
AKDMLFATLDPTMRAVTLPDGTDVILSDTVGFISDLPTQLVAAFRATLEEVLDADLIVHVRDISHPQTVEQAEDVHAILG
DLGVSDQSAQLEVWNKVDLLDEAAQTARQVEADRNEAIFATSALTGAGMDDFLTAVSHTLSPPRLEAVVELPHSDGRKRA
WLFEQGVVEREEPTEIGTQLTVLWTTRQQKAFRAL

Sequences:

>Translated_435_residues
MSAGLRATDGDDEGLEKGPMRALVLHPDIKSDRTRRDPAFALEEGVALAAALPDLEVVDAQVVRLPRAQPGLLFGSGKIQ
ELHDLIEALDIGLVLIDGPVTPVQQRNLEREWGCKLLDRTGLILEIFADRAATREGVLQVELAALSYQRTRLVRAWTHLE
RQRGGLGFVGGPGETQIEADRRAIDEAVTRIKRQLAKVVKTRALHRSARAKVPYPIVALVGYTNAGKSTLFNRLTGADVM
AKDMLFATLDPTMRAVTLPDGTDVILSDTVGFISDLPTQLVAAFRATLEEVLDADLIVHVRDISHPQTVEQAEDVHAILG
DLGVSDQSAQLEVWNKVDLLDEAAQTARQVEADRNEAIFATSALTGAGMDDFLTAVSHTLSPPRLEAVVELPHSDGRKRA
WLFEQGVVEREEPTEIGTQLTVLWTTRQQKAFRAL
>Mature_434_residues
SAGLRATDGDDEGLEKGPMRALVLHPDIKSDRTRRDPAFALEEGVALAAALPDLEVVDAQVVRLPRAQPGLLFGSGKIQE
LHDLIEALDIGLVLIDGPVTPVQQRNLEREWGCKLLDRTGLILEIFADRAATREGVLQVELAALSYQRTRLVRAWTHLER
QRGGLGFVGGPGETQIEADRRAIDEAVTRIKRQLAKVVKTRALHRSARAKVPYPIVALVGYTNAGKSTLFNRLTGADVMA
KDMLFATLDPTMRAVTLPDGTDVILSDTVGFISDLPTQLVAAFRATLEEVLDADLIVHVRDISHPQTVEQAEDVHAILGD
LGVSDQSAQLEVWNKVDLLDEAAQTARQVEADRNEAIFATSALTGAGMDDFLTAVSHTLSPPRLEAVVELPHSDGRKRAW
LFEQGVVEREEPTEIGTQLTVLWTTRQQKAFRAL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=238, Percent_Identity=37.3949579831933, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI310133116, Length=290, Percent_Identity=33.1034482758621, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI310124269, Length=271, Percent_Identity=33.210332103321, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI310124267, Length=271, Percent_Identity=33.210332103321, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI310124171, Length=271, Percent_Identity=33.210332103321, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI310124169, Length=271, Percent_Identity=33.210332103321, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1790615, Length=350, Percent_Identity=44.5714285714286, Blast_Score=277, Evalue=8e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=373, Percent_Identity=31.6353887399464, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24650079, Length=411, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47602; Mature: 47471

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGLRATDGDDEGLEKGPMRALVLHPDIKSDRTRRDPAFALEEGVALAAALPDLEVVDA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCEEEHHCCCCHHHHH
QVVRLPRAQPGLLFGSGKIQELHDLIEALDIGLVLIDGPVTPVQQRNLEREWGCKLLDRT
HHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCHHHCCHHHHCC
GLILEIFADRAATREGVLQVELAALSYQRTRLVRAWTHLERQRGGLGFVGGPGETQIEAD
CCEEEEHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHH
RRAIDEAVTRIKRQLAKVVKTRALHRSARAKVPYPIVALVGYTNAGKSTLFNRLTGADVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHH
AKDMLFATLDPTMRAVTLPDGTDVILSDTVGFISDLPTQLVAAFRATLEEVLDADLIVHV
HHHHHHEECCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
RDISHPQTVEQAEDVHAILGDLGVSDQSAQLEVWNKVDLLDEAAQTARQVEADRNEAIFA
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TSALTGAGMDDFLTAVSHTLSPPRLEAVVELPHSDGRKRAWLFEQGVVEREEPTEIGTQL
ECCCCCCCHHHHHHHHHHCCCCHHHHHHEECCCCCCCCEEEEHHCCCCCCCCCHHHCCEE
TVLWTTRQQKAFRAL
EEEEECCHHHHHHCC
>Mature Secondary Structure 
SAGLRATDGDDEGLEKGPMRALVLHPDIKSDRTRRDPAFALEEGVALAAALPDLEVVDA
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCEEEHHCCCCHHHHH
QVVRLPRAQPGLLFGSGKIQELHDLIEALDIGLVLIDGPVTPVQQRNLEREWGCKLLDRT
HHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCHHHCCHHHHCC
GLILEIFADRAATREGVLQVELAALSYQRTRLVRAWTHLERQRGGLGFVGGPGETQIEAD
CCEEEEHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHH
RRAIDEAVTRIKRQLAKVVKTRALHRSARAKVPYPIVALVGYTNAGKSTLFNRLTGADVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHH
AKDMLFATLDPTMRAVTLPDGTDVILSDTVGFISDLPTQLVAAFRATLEEVLDADLIVHV
HHHHHHEECCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
RDISHPQTVEQAEDVHAILGDLGVSDQSAQLEVWNKVDLLDEAAQTARQVEADRNEAIFA
ECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TSALTGAGMDDFLTAVSHTLSPPRLEAVVELPHSDGRKRAWLFEQGVVEREEPTEIGTQL
ECCCCCCCHHHHHHHHHHCCCCHHHHHHEECCCCCCCCEEEEHHCCCCCCCCCHHHCCEE
TVLWTTRQQKAFRAL
EEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]