Click here to switch to the map view.

The map label for this gene is hfq

Identifier: 89054735

GI number: 89054735

Start: 2252412

End: 2252645

Strand: Direct

Name: hfq

Synonym: Jann_2244

Alternate gene names: 89054735

Gene position: 2252412-2252645 (Clockwise)

Preceding gene: 89054734

Following gene: 89054736

Centisome position: 52.16

GC content: 51.71

Gene sequence:

>234_bases
ATGGCCGAAAATAAACAAAACTTGCAGGACGCGTTTCTTAATCACGTGCGCAAGACCAAAGTACCGGTAACGATTTTTTT
GATCAACGGCGTGAAGCTGCAAGGCGTGATCACGTGGTTTGACAACTTCTGTGTTCTGCTGCGCCGCGATGGCCAGTCGC
AACTTGTCTACAAGCACGCGATTTCCACCGTCATGCCAGCCCAACCCATCAGCCTCTACGACGGGGAAGAGTGA

Upstream 100 bases:

>100_bases
ATCCAAGCAGAATCGAGGACATAGTGCCCAGGCACGCATGCAACCGGACGAAACTCCGGGTGAATAACACCAACAGGGCG
CCAGTAGGGCGTATGAAAAA

Downstream 100 bases:

>100_bases
GCGCGGGATTGCGCGCCACGGACGGGGATGATGAGGGTCTTGAAAAAGGCCCAATGCGGGCGCTTGTCTTGCATCCGGAC
ATCAAATCCGACCGCACCCG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 77; Mature: 76

Protein sequence:

>77_residues
MAENKQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHAISTVMPAQPISLYDGEE

Sequences:

>Translated_77_residues
MAENKQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHAISTVMPAQPISLYDGEE
>Mature_76_residues
AENKQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHAISTVMPAQPISLYDGEE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=69, Percent_Identity=56.5217391304348, Blast_Score=87, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8789; Mature: 8658

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENKQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHA
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEECCCEEEEEECCCCCHHHHHHH
ISTVMPAQPISLYDGEE
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AENKQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHA
CCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEECCCEEEEEECCCCCHHHHHHH
ISTVMPAQPISLYDGEE
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA