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The map label for this gene is trkA

Identifier: 89054733

GI number: 89054733

Start: 2249368

End: 2250744

Strand: Direct

Name: trkA

Synonym: Jann_2242

Alternate gene names: 89054733

Gene position: 2249368-2250744 (Clockwise)

Preceding gene: 89054731

Following gene: 89054734

Centisome position: 52.09

GC content: 63.25

Gene sequence:

>1377_bases
ATGAAGGTCATCATCTGCGGTGCGGGCCAGGTTGGCTGGCAGATCGCGCGGCATCTGTCTTCGGAAAACAATGACGTCAC
GGTCGTGGACAACAATCCCGATCTGGTGCGGCGCGCGACGGATATGCTGGACGTGCAGGGCCTGACAGGCTTTGCCAGCC
ACCCCGAAATTCTGGACCGTGCGGGCGCGCGGGATGCGGATATGGTGATCGCGGCGACGTTCTCGGACGAGGTCAACATG
GTCACCTGCCAGGTCGCGCATTCCGTCTTTGCCGTGCCGCGCAAGATCGCGCGCCTGCGGGCGCAGAGCTATCTGGATAC
AATCTATTCCGATCTCTATCGCCGCGACCATCTACCGATCGATGTTGTGATCTCGCCGGAGAAGGAGGTGGCGGAGGCGG
TGCTGAATCGTATCGCGTCGCCCTCGACCTTCGATACGGAAAACTTTCTGGGCGGCGCGGTGCAGCTGATGGGGATCGTG
CTGGATGAGGATTGCCCGGTCCTCGACACACCGCTGCGGCAATTGTCGGAGCTATTCTCAACCCTGCGCGCCATCGTGGT
GGGCATCCGGCGGGACGGCACGCTGTTTGCGCCTGAGCCCGGGGATCAGATGTTTGCGGGCGATCAGATCTATGTCTTTA
CCCATATCGACGATGTGGCCCGGGCGCTGGAGATTTTCGGCAAAAGCCGCGCCCTGCCGGAACGGATCCTGATCATCGGC
GGCGGCAATGTCGGGCTGACCGTGGCCTCCAAGCTGGAGAAATCGGCCACGCGGATGCGCACCCGTGTTATTGAGGCGAA
CCGGACCCAGGCGGAGCGGGCGGCGGATGCGCTGGAGCGCACCATCGTGCTGCATGGCGACGGGTTGGACGTGGACCTGC
TGCGCGAGGCCAGCGTAGAGCGCGCCGATGTCGTGCTGTGCCTGACCGATGACGACAAGACCAATATGCTGGCCTCCGTG
CGGGCAAAATCGGCGGGCGCGGGCATGGCGATCAGCCTGGTGAATGACCCGACACTGGTGCCGCTGATGGCGCCGTTGGG
CATTGATGCCTATGTGAACCCGCGCTCTACCACCGTGAGTTCCATCCTGCGCCACATTCGCCATGGCCGGGTGCGCGGCG
TCTATTCCATTGGCGATGCCGAGGCCGAGATTATCGAGGCGCAGGTTCTGTCCACATCGCCCATCTCGGGCAAGGCCGTG
CGCGATATCGACTTCCCGGAAGGCGCGCTTTTGGGGGCGGTGCAGCGCGGCAAGGAAATTTTCCGACCAACGGGCGCGGT
TCGGATCGAGGAGGGCGACGTCGTGGTCATCTTCGCGCTGGCCCCCGATGTGCCAGCGGTTGAGGCGCTTCTGCAAGTCT
CCATCGACTTTTTCTGA

Upstream 100 bases:

>100_bases
CACGGCAATTGTCCAATCAATCATTTCAACCCTTTCGCTTTATGGGTAATGCTTGCAGAGGCGTCCCGTTCGGACAAGCA
GGTTAAGGGTACACCTCCAC

Downstream 100 bases:

>100_bases
CCGCCCGCGCCATGGCCGCTTATTTCCGCAATCTGCCCTTCTTCGTGATCCTGATTTTCGTGGCGGGCGGGGCGATGCTG
GCCCCATCTGCGGTGGCGCT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVIICGAGQVGWQIARHLSSENNDVTVVDNNPDLVRRATDMLDVQGLTGFASHPEILDRAGARDADMVIAATFSDEVNM
VTCQVAHSVFAVPRKIARLRAQSYLDTIYSDLYRRDHLPIDVVISPEKEVAEAVLNRIASPSTFDTENFLGGAVQLMGIV
LDEDCPVLDTPLRQLSELFSTLRAIVVGIRRDGTLFAPEPGDQMFAGDQIYVFTHIDDVARALEIFGKSRALPERILIIG
GGNVGLTVASKLEKSATRMRTRVIEANRTQAERAADALERTIVLHGDGLDVDLLREASVERADVVLCLTDDDKTNMLASV
RAKSAGAGMAISLVNDPTLVPLMAPLGIDAYVNPRSTTVSSILRHIRHGRVRGVYSIGDAEAEIIEAQVLSTSPISGKAV
RDIDFPEGALLGAVQRGKEIFRPTGAVRIEEGDVVVIFALAPDVPAVEALLQVSIDFF

Sequences:

>Translated_458_residues
MKVIICGAGQVGWQIARHLSSENNDVTVVDNNPDLVRRATDMLDVQGLTGFASHPEILDRAGARDADMVIAATFSDEVNM
VTCQVAHSVFAVPRKIARLRAQSYLDTIYSDLYRRDHLPIDVVISPEKEVAEAVLNRIASPSTFDTENFLGGAVQLMGIV
LDEDCPVLDTPLRQLSELFSTLRAIVVGIRRDGTLFAPEPGDQMFAGDQIYVFTHIDDVARALEIFGKSRALPERILIIG
GGNVGLTVASKLEKSATRMRTRVIEANRTQAERAADALERTIVLHGDGLDVDLLREASVERADVVLCLTDDDKTNMLASV
RAKSAGAGMAISLVNDPTLVPLMAPLGIDAYVNPRSTTVSSILRHIRHGRVRGVYSIGDAEAEIIEAQVLSTSPISGKAV
RDIDFPEGALLGAVQRGKEIFRPTGAVRIEEGDVVVIFALAPDVPAVEALLQVSIDFF
>Mature_458_residues
MKVIICGAGQVGWQIARHLSSENNDVTVVDNNPDLVRRATDMLDVQGLTGFASHPEILDRAGARDADMVIAATFSDEVNM
VTCQVAHSVFAVPRKIARLRAQSYLDTIYSDLYRRDHLPIDVVISPEKEVAEAVLNRIASPSTFDTENFLGGAVQLMGIV
LDEDCPVLDTPLRQLSELFSTLRAIVVGIRRDGTLFAPEPGDQMFAGDQIYVFTHIDDVARALEIFGKSRALPERILIIG
GGNVGLTVASKLEKSATRMRTRVIEANRTQAERAADALERTIVLHGDGLDVDLLREASVERADVVLCLTDDDKTNMLASV
RAKSAGAGMAISLVNDPTLVPLMAPLGIDAYVNPRSTTVSSILRHIRHGRVRGVYSIGDAEAEIIEAQVLSTSPISGKAV
RDIDFPEGALLGAVQRGKEIFRPTGAVRIEEGDVVVIFALAPDVPAVEALLQVSIDFF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=465, Percent_Identity=35.6989247311828, Blast_Score=268, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49553; Mature: 49553

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIICGAGQVGWQIARHLSSENNDVTVVDNNPDLVRRATDMLDVQGLTGFASHPEILDR
CEEEEECCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AGARDADMVIAATFSDEVNMVTCQVAHSVFAVPRKIARLRAQSYLDTIYSDLYRRDHLPI
CCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
DVVISPEKEVAEAVLNRIASPSTFDTENFLGGAVQLMGIVLDEDCPVLDTPLRQLSELFS
EEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHH
TLRAIVVGIRRDGTLFAPEPGDQMFAGDQIYVFTHIDDVARALEIFGKSRALPERILIIG
HHHHHHEEECCCCCEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEEEE
GGNVGLTVASKLEKSATRMRTRVIEANRTQAERAADALERTIVLHGDGLDVDLLREASVE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHCCCC
RADVVLCLTDDDKTNMLASVRAKSAGAGMAISLVNDPTLVPLMAPLGIDAYVNPRSTTVS
CCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEECCCHHHHH
SILRHIRHGRVRGVYSIGDAEAEIIEAQVLSTSPISGKAVRDIDFPEGALLGAVQRGKEI
HHHHHHHCCCEEEEEEECCCHHHHHEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHH
FRPTGAVRIEEGDVVVIFALAPDVPAVEALLQVSIDFF
HCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVIICGAGQVGWQIARHLSSENNDVTVVDNNPDLVRRATDMLDVQGLTGFASHPEILDR
CEEEEECCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AGARDADMVIAATFSDEVNMVTCQVAHSVFAVPRKIARLRAQSYLDTIYSDLYRRDHLPI
CCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
DVVISPEKEVAEAVLNRIASPSTFDTENFLGGAVQLMGIVLDEDCPVLDTPLRQLSELFS
EEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHH
TLRAIVVGIRRDGTLFAPEPGDQMFAGDQIYVFTHIDDVARALEIFGKSRALPERILIIG
HHHHHHEEECCCCCEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEEEE
GGNVGLTVASKLEKSATRMRTRVIEANRTQAERAADALERTIVLHGDGLDVDLLREASVE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHCCCC
RADVVLCLTDDDKTNMLASVRAKSAGAGMAISLVNDPTLVPLMAPLGIDAYVNPRSTTVS
CCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEECCCHHHHH
SILRHIRHGRVRGVYSIGDAEAEIIEAQVLSTSPISGKAVRDIDFPEGALLGAVQRGKEI
HHHHHHHCCCEEEEEEECCCHHHHHEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHH
FRPTGAVRIEEGDVVVIFALAPDVPAVEALLQVSIDFF
HCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]