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The map label for this gene is cbrB [H]

Identifier: 89054614

GI number: 89054614

Start: 2132322

End: 2133305

Strand: Direct

Name: cbrB [H]

Synonym: Jann_2123

Alternate gene names: 89054614

Gene position: 2132322-2133305 (Clockwise)

Preceding gene: 89054612

Following gene: 89054615

Centisome position: 49.38

GC content: 66.67

Gene sequence:

>984_bases
ATGCGGGCCGGAAATACAATCCTTATAGCAGGAGCGATCTGCCTAGCTGTCCTCAGCTTGCACCTGGGTGTCCGGACCTA
TGCCCCGGCGGAGATATGGCGCGCGTTAACAAGCGCGGACGCGGACGCGACCGCGATCATCGTCCGCGACCTCCGCGTGC
CGCGCATGGTGCTGGCCGCCTTGATCGGTGCGGCCCTGGCCCTGTCAGGTCTGATGATGCAATCGGTGACGCGCAATCCA
GTGGCGGAGCCCGGCCTTCTGGGCGTGAATGCAGGCGCGGCCTTTGCGGTCGTGGTTCTGCTGACCGTCCAACCGGGCGC
GGGCGTATGGCTGGTCATAGGGGTTGCGGCGATGGGTGCGGCCCTCGCGGCTGCGTTGGTCTTTGGGCTCGCATTGTCCA
TCGGCGCTGCGATGTCGCCGGTGCATCTGCTGCTGGCGGGGGTCACGGTGGCCGCGTTGTTGATGGCGGGCGTACAGGTG
TTGATCATCCTCAACGAGCAGACGTTGGAAGAGCTTATCTTCTGGCTCTCCGGCTCCTTCGCGGACAGGCCTATTGTGGG
GATCTCGGTCGTGGCGGCTGGATTGGGTCTGGGCGGCGGTCTGTGCCTGTTCCAAGCCCCTGCATTGGACGCTTTGGGGG
CCGATGATGCGACCGCCACAGGCCTGGGCGTCGATGTCCCCCGCCTGCGGCTGCTGCTTCTGGGATGTGCTGCTTTGCTT
GCGGGCTGTGCCGTGGCCCTGGCCGGGCCGATCGCCTTTGTGGGCCTTGTTGCGCCGCGTCTGGCACGGTTGAGCGGTGC
ACGGGGCCACGCCCAGTTGATCCCCCGCGCGGTGCTGTTCGGCGTGCTCCTCGCCCTCTCCGCAGATCTGATCGCGCGCT
TCGTCCTGTACCCGTCCGAGGCGCCCGTCAGCGCGGTGATGGCGCTGATCGGCGTTCCGATCCTGATCGGCCTGCTGCGC
GGCACAAGGATGCGACTGGCATGA

Upstream 100 bases:

>100_bases
GGTTGCAAGAATTGACAGGCGCATGGCGGATCGTCCTTGATGTTGAGTATTTTAGTCAGATAATAGGCTGACAGAAATAG
TTAGAAATGCAAGGGTCAGA

Downstream 100 bases:

>100_bases
CGGCCGCGCGCATCAGTTTGCCCGTGGCGCTCATGGCGCTGGCGCTTGTGGCCGCCGCGATGGGAAGCTCCTTCATGCCG
CTTGACCGGATCATCGCGGC

Product: transport system permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRAGNTILIAGAICLAVLSLHLGVRTYAPAEIWRALTSADADATAIIVRDLRVPRMVLAALIGAALALSGLMMQSVTRNP
VAEPGLLGVNAGAAFAVVVLLTVQPGAGVWLVIGVAAMGAALAAALVFGLALSIGAAMSPVHLLLAGVTVAALLMAGVQV
LIILNEQTLEELIFWLSGSFADRPIVGISVVAAGLGLGGGLCLFQAPALDALGADDATATGLGVDVPRLRLLLLGCAALL
AGCAVALAGPIAFVGLVAPRLARLSGARGHAQLIPRAVLFGVLLALSADLIARFVLYPSEAPVSAVMALIGVPILIGLLR
GTRMRLA

Sequences:

>Translated_327_residues
MRAGNTILIAGAICLAVLSLHLGVRTYAPAEIWRALTSADADATAIIVRDLRVPRMVLAALIGAALALSGLMMQSVTRNP
VAEPGLLGVNAGAAFAVVVLLTVQPGAGVWLVIGVAAMGAALAAALVFGLALSIGAAMSPVHLLLAGVTVAALLMAGVQV
LIILNEQTLEELIFWLSGSFADRPIVGISVVAAGLGLGGGLCLFQAPALDALGADDATATGLGVDVPRLRLLLLGCAALL
AGCAVALAGPIAFVGLVAPRLARLSGARGHAQLIPRAVLFGVLLALSADLIARFVLYPSEAPVSAVMALIGVPILIGLLR
GTRMRLA
>Mature_327_residues
MRAGNTILIAGAICLAVLSLHLGVRTYAPAEIWRALTSADADATAIIVRDLRVPRMVLAALIGAALALSGLMMQSVTRNP
VAEPGLLGVNAGAAFAVVVLLTVQPGAGVWLVIGVAAMGAALAAALVFGLALSIGAAMSPVHLLLAGVTVAALLMAGVQV
LIILNEQTLEELIFWLSGSFADRPIVGISVVAAGLGLGGGLCLFQAPALDALGADDATATGLGVDVPRLRLLLLGCAALL
AGCAVALAGPIAFVGLVAPRLARLSGARGHAQLIPRAVLFGVLLALSADLIARFVLYPSEAPVSAVMALIGVPILIGLLR
GTRMRLA

Specific function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=302, Percent_Identity=38.0794701986755, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=35.7142857142857, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1790740, Length=313, Percent_Identity=36.1022364217252, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1788004, Length=275, Percent_Identity=33.0909090909091, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=33.8028169014084, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786804, Length=269, Percent_Identity=32.3420074349442, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32872; Mature: 32872

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGNTILIAGAICLAVLSLHLGVRTYAPAEIWRALTSADADATAIIVRDLRVPRMVLAA
CCCCCEEEHHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCCCHHEEHHHHCCHHHHHHHH
LIGAALALSGLMMQSVTRNPVAEPGLLGVNAGAAFAVVVLLTVQPGAGVWLVIGVAAMGA
HHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHEECCCCCHHHHHHHHHHHH
ALAAALVFGLALSIGAAMSPVHLLLAGVTVAALLMAGVQVLIILNEQTLEELIFWLSGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEECHHHHHHHHHHHCCCC
ADRPIVGISVVAAGLGLGGGLCLFQAPALDALGADDATATGLGVDVPRLRLLLLGCAALL
CCCCCHHHHHHHHHHCCCCCHHHEECCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGCAVALAGPIAFVGLVAPRLARLSGARGHAQLIPRAVLFGVLLALSADLIARFVLYPSE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APVSAVMALIGVPILIGLLRGTRMRLA
CCHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MRAGNTILIAGAICLAVLSLHLGVRTYAPAEIWRALTSADADATAIIVRDLRVPRMVLAA
CCCCCEEEHHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCCCHHEEHHHHCCHHHHHHHH
LIGAALALSGLMMQSVTRNPVAEPGLLGVNAGAAFAVVVLLTVQPGAGVWLVIGVAAMGA
HHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHEECCCCCHHHHHHHHHHHH
ALAAALVFGLALSIGAAMSPVHLLLAGVTVAALLMAGVQVLIILNEQTLEELIFWLSGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEECHHHHHHHHHHHCCCC
ADRPIVGISVVAAGLGLGGGLCLFQAPALDALGADDATATGLGVDVPRLRLLLLGCAALL
CCCCCHHHHHHHHHHCCCCCHHHEECCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGCAVALAGPIAFVGLVAPRLARLSGARGHAQLIPRAVLFGVLLALSADLIARFVLYPSE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APVSAVMALIGVPILIGLLRGTRMRLA
CCHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8596459 [H]