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The map label for this gene is rbsK [H]

Identifier: 89054612

GI number: 89054612

Start: 2130110

End: 2131033

Strand: Direct

Name: rbsK [H]

Synonym: Jann_2121

Alternate gene names: 89054612

Gene position: 2130110-2131033 (Clockwise)

Preceding gene: 89054611

Following gene: 89054614

Centisome position: 49.33

GC content: 63.96

Gene sequence:

>924_bases
ATGAGCCATGATGTCGTCATTCTGGGCGTGTTCGTGGCCGACACCGCGTACCGTGCTGATCGCCAGCCAAAGATGGGTGA
AACGATCCTGGGCAAGTCATTCGCGCTGGGGCCGGGCGGGAAAGGCTCCAACCAGGCGGTGGCTGCCGGAATGGCCGGTG
GCGACGTCGGGTTCATCACGAAACTCGGGAAAGATCCGTTTGCCGACATGGCGCTTGCCACGTGGGACAAGGCCGGGGTG
ACCTCGCTCGCGTCCCAACATGCCGATAGCTACACCGGGGCGGCATATATCTTCATCGAAGAAGCCACGGGTAATAACGC
CATCATCGTCAGCCCCGGCATTGCCGCCACGATCAGCGTTGCGGATATCGACGCCCATGCCAATACGGTCCGCACTGCCA
AGGTTTTCATGACACAGCTTGAGCAACCCCTGGACGCCGCCGAACACGCATTGGGCCTGGCGCGCGCTGGCGGGGCCATC
ACCATTCTCAATCCCGCCCCCGCTGCTGAGCTGCCAGACAGCATGCTGGCCCTGTGCGATTACGTGACCCCGAATGAGAC
CGAGACCGAGGCGTTGACGGGCATTCCGGTGCAGACCACCGCCGATGCCACCCGCGCGGCGGAGGCGCTATTGGCCCGTG
GCGTCAAGGCCGCGATCATCACCTTGGGCGAAAACGGCTGCCTTTTTCACGATGGTCAAAGCGCCGTGCATATTCCCGCG
ATCTCAGCGGGGCCGGTTGTGGAAACCACAGGTGCAGGCGATGCGTTCAACGGCGGGTTTGCCGCCGCGCTGGCCGAAGG
TATGGCGCCACTTGAGGCGATCCGGTTGGGCACCGCCACTGCCGCGATTTCCGTCACCCGGGCAGGCACCGCCCCCTCCA
TGCCGGCCCGCTCAGAAATTGACGCTCTGCTTGCGTCGGGTTGA

Upstream 100 bases:

>100_bases
TCTACGACCAGGCCCGCGAAAGCTATGCCGTCATTCAGACCGGTGAGCGCCGGTTTTACGGCTGCTTTATCCTGCGCAAA
GGTGTGATCGGACCCGACGC

Downstream 100 bases:

>100_bases
GCGGGGACCGTTGGCATTGCGCCCCGCAGATCGGTCGCGCCACGACCAAAGCTGATCTCCGGTTCGTTGACCCGTTCAGC
CCAATAACAGTCCGTAATTG

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSHDVVILGVFVADTAYRADRQPKMGETILGKSFALGPGGKGSNQAVAAGMAGGDVGFITKLGKDPFADMALATWDKAGV
TSLASQHADSYTGAAYIFIEEATGNNAIIVSPGIAATISVADIDAHANTVRTAKVFMTQLEQPLDAAEHALGLARAGGAI
TILNPAPAAELPDSMLALCDYVTPNETETEALTGIPVQTTADATRAAEALLARGVKAAIITLGENGCLFHDGQSAVHIPA
ISAGPVVETTGAGDAFNGGFAAALAEGMAPLEAIRLGTATAAISVTRAGTAPSMPARSEIDALLASG

Sequences:

>Translated_307_residues
MSHDVVILGVFVADTAYRADRQPKMGETILGKSFALGPGGKGSNQAVAAGMAGGDVGFITKLGKDPFADMALATWDKAGV
TSLASQHADSYTGAAYIFIEEATGNNAIIVSPGIAATISVADIDAHANTVRTAKVFMTQLEQPLDAAEHALGLARAGGAI
TILNPAPAAELPDSMLALCDYVTPNETETEALTGIPVQTTADATRAAEALLARGVKAAIITLGENGCLFHDGQSAVHIPA
ISAGPVVETTGAGDAFNGGFAAALAEGMAPLEAIRLGTATAAISVTRAGTAPSMPARSEIDALLASG
>Mature_306_residues
SHDVVILGVFVADTAYRADRQPKMGETILGKSFALGPGGKGSNQAVAAGMAGGDVGFITKLGKDPFADMALATWDKAGVT
SLASQHADSYTGAAYIFIEEATGNNAIIVSPGIAATISVADIDAHANTVRTAKVFMTQLEQPLDAAEHALGLARAGGAIT
ILNPAPAAELPDSMLALCDYVTPNETETEALTGIPVQTTADATRAAEALLARGVKAAIITLGENGCLFHDGQSAVHIPAI
SAGPVVETTGAGDAFNGGFAAALAEGMAPLEAIRLGTATAAISVTRAGTAPSMPARSEIDALLASG

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=298, Percent_Identity=37.248322147651, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=40.9240924092409, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI87081971, Length=285, Percent_Identity=27.719298245614, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=27.3026315789474, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788491, Length=289, Percent_Identity=22.8373702422145, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=36.7549668874172, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=29.0419161676647, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322565, Length=285, Percent_Identity=27.719298245614, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=36.4238410596026, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=30.794701986755, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30839; Mature: 30708

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDVVILGVFVADTAYRADRQPKMGETILGKSFALGPGGKGSNQAVAAGMAGGDVGFIT
CCCCEEEEEEEEHHHHHHCCCCCCCCCHHHCCEEECCCCCCCCCCEEEEECCCCCCHHHH
KLGKDPFADMALATWDKAGVTSLASQHADSYTGAAYIFIEEATGNNAIIVSPGIAATISV
HCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCEEEEEE
ADIDAHANTVRTAKVFMTQLEQPLDAAEHALGLARAGGAITILNPAPAAELPDSMLALCD
EEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHH
YVTPNETETEALTGIPVQTTADATRAAEALLARGVKAAIITLGENGCLFHDGQSAVHIPA
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCEEEECC
ISAGPVVETTGAGDAFNGGFAAALAEGMAPLEAIRLGTATAAISVTRAGTAPSMPARSEI
CCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHCCHHEEEEEEECCCCCCCCCHHHH
DALLASG
HHHHCCC
>Mature Secondary Structure 
SHDVVILGVFVADTAYRADRQPKMGETILGKSFALGPGGKGSNQAVAAGMAGGDVGFIT
CCCEEEEEEEEHHHHHHCCCCCCCCCHHHCCEEECCCCCCCCCCEEEEECCCCCCHHHH
KLGKDPFADMALATWDKAGVTSLASQHADSYTGAAYIFIEEATGNNAIIVSPGIAATISV
HCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCEEEEEE
ADIDAHANTVRTAKVFMTQLEQPLDAAEHALGLARAGGAITILNPAPAAELPDSMLALCD
EEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHH
YVTPNETETEALTGIPVQTTADATRAAEALLARGVKAAIITLGENGCLFHDGQSAVHIPA
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCEEEECC
ISAGPVVETTGAGDAFNGGFAAALAEGMAPLEAIRLGTATAAISVTRAGTAPSMPARSEI
CCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHCCHHEEEEEEECCCCCCCCCHHHH
DALLASG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]