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The map label for this gene is iolC [H]

Identifier: 89053910

GI number: 89053910

Start: 1387420

End: 1388400

Strand: Reverse

Name: iolC [H]

Synonym: Jann_1419

Alternate gene names: 89053910

Gene position: 1388400-1387420 (Counterclockwise)

Preceding gene: 89053911

Following gene: 89053909

Centisome position: 32.15

GC content: 58.72

Gene sequence:

>981_bases
ATGAAGTTGCGCGGCAATAATTTCGTGATCATTGGCCGGGCTGGCATGGATCTCTACCCGGATCCTCCCGGCACACGGAC
CGAAGATGCGACCCACTTCTTTACGTGTCTTGGCGGATCTTCGGCCAATATCGGCGTTGCGATCACAAAGCTCGGCGGCA
AGGCGTCCCTCGTGACGCGCGTCGCCGATGACGCCATCGGGCGGTTTTGCTGCAATCAACTGGACCTCTATGGTATTGAT
CGGACACATGTAATTGCTCAAGGGGGCCAGGCTCGAAATTCTCTCGCCTTGGTCGAAACCCGGATCGAAGATCACCAATC
CGTCATCTACCGCAACGGCGCCGCGGATTTTGAGATGACCCAAGCCGACGTCGAGGCCGTGGACTTTGCCACCTTTGATG
CCCTGATCACCACCGGTACGGTTTTTGCAGCAGAGCCCTCGCGCAGTGCCGCGTTCCGGGCATTCGAACTGGCCAAATCG
GCTGGAATTCCGTTGATTTTTGACGTCGATTATCGACCATACTCTTGGCCTTCGCCCGACGTTGCGGCAGACGTCTATTC
TAGGGCAGGTGCGATGTGTGACGTGATCGTGGGCAACGATATCGAGTTCGGGTTTATGGCTGGGAACTATGATCAAGGCC
TTGATAAAGCGCGTGAATTAGTTGCGAATGGCGCGAAGATTGCAGTCTACAAGATGGGCGAAGAGGGTGCAATTACGATC
ACGCCGGAGCCCGAAGTGCGGACCGGAATCTACCGCACGGAGGCGCTGAAGCCCACGGGTGCGGGCGACAGCTTCATGGG
TGGTTTTGTTTCGGGGCTCACCGATGGCCTATCCGTGAGCGACGCCGTGTTGCAGGGGTCCGCAGCCGCCGCAATGGTTG
TGGCAAGGGTCGGATGCGCCCCAGCGATGCCCACGCGGTCTGAGTTGGACGCGTTTTTGAACGATCACCCAGGGCCAACG
GCCCCCAGCGACCCGGCCTGA

Upstream 100 bases:

>100_bases
GGTGGGAAGTTGGGACGGCCCAGGTGTCCGACAACCCGAATGTCCGCGAAAAGCATGCGGAATGGGAAGCGGACCGTAAC
AAGCAGCGACAGGGCGTGTG

Downstream 100 bases:

>100_bases
AAGGACGCGTTAACCATGCACATCCCCCCCTTTGACAACCAAAACCAGGCCATCGTGGGTGAAGGCGACGCGCATGTTCC
GCTAACGTATTTCAATATCG

Product: PfkB

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKLRGNNFVIIGRAGMDLYPDPPGTRTEDATHFFTCLGGSSANIGVAITKLGGKASLVTRVADDAIGRFCCNQLDLYGID
RTHVIAQGGQARNSLALVETRIEDHQSVIYRNGAADFEMTQADVEAVDFATFDALITTGTVFAAEPSRSAAFRAFELAKS
AGIPLIFDVDYRPYSWPSPDVAADVYSRAGAMCDVIVGNDIEFGFMAGNYDQGLDKARELVANGAKIAVYKMGEEGAITI
TPEPEVRTGIYRTEALKPTGAGDSFMGGFVSGLTDGLSVSDAVLQGSAAAAMVVARVGCAPAMPTRSELDAFLNDHPGPT
APSDPA

Sequences:

>Translated_326_residues
MKLRGNNFVIIGRAGMDLYPDPPGTRTEDATHFFTCLGGSSANIGVAITKLGGKASLVTRVADDAIGRFCCNQLDLYGID
RTHVIAQGGQARNSLALVETRIEDHQSVIYRNGAADFEMTQADVEAVDFATFDALITTGTVFAAEPSRSAAFRAFELAKS
AGIPLIFDVDYRPYSWPSPDVAADVYSRAGAMCDVIVGNDIEFGFMAGNYDQGLDKARELVANGAKIAVYKMGEEGAITI
TPEPEVRTGIYRTEALKPTGAGDSFMGGFVSGLTDGLSVSDAVLQGSAAAAMVVARVGCAPAMPTRSELDAFLNDHPGPT
APSDPA
>Mature_326_residues
MKLRGNNFVIIGRAGMDLYPDPPGTRTEDATHFFTCLGGSSANIGVAITKLGGKASLVTRVADDAIGRFCCNQLDLYGID
RTHVIAQGGQARNSLALVETRIEDHQSVIYRNGAADFEMTQADVEAVDFATFDALITTGTVFAAEPSRSAAFRAFELAKS
AGIPLIFDVDYRPYSWPSPDVAADVYSRAGAMCDVIVGNDIEFGFMAGNYDQGLDKARELVANGAKIAVYKMGEEGAITI
TPEPEVRTGIYRTEALKPTGAGDSFMGGFVSGLTDGLSVSDAVLQGSAAAAMVVARVGCAPAMPTRSELDAFLNDHPGPT
APSDPA

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1789775, Length=266, Percent_Identity=27.0676691729323, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081971, Length=287, Percent_Identity=24.0418118466899, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=25.4125412541254, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 34307; Mature: 34307

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRGNNFVIIGRAGMDLYPDPPGTRTEDATHFFTCLGGSSANIGVAITKLGGKASLVTR
CEECCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHH
VADDAIGRFCCNQLDLYGIDRTHVIAQGGQARNSLALVETRIEDHQSVIYRNGAADFEMT
HHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCCEEEEHHHHHHHHEEEEECCCCCCEEH
QADVEAVDFATFDALITTGTVFAAEPSRSAAFRAFELAKSAGIPLIFDVDYRPYSWPSPD
HHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
VAADVYSRAGAMCDVIVGNDIEFGFMAGNYDQGLDKARELVANGAKIAVYKMGEEGAITI
HHHHHHHHCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEE
TPEPEVRTGIYRTEALKPTGAGDSFMGGFVSGLTDGLSVSDAVLQGSAAAAMVVARVGCA
CCCCCHHHCEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCC
PAMPTRSELDAFLNDHPGPTAPSDPA
CCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKLRGNNFVIIGRAGMDLYPDPPGTRTEDATHFFTCLGGSSANIGVAITKLGGKASLVTR
CEECCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHH
VADDAIGRFCCNQLDLYGIDRTHVIAQGGQARNSLALVETRIEDHQSVIYRNGAADFEMT
HHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCCEEEEHHHHHHHHEEEEECCCCCCEEH
QADVEAVDFATFDALITTGTVFAAEPSRSAAFRAFELAKSAGIPLIFDVDYRPYSWPSPD
HHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
VAADVYSRAGAMCDVIVGNDIEFGFMAGNYDQGLDKARELVANGAKIAVYKMGEEGAITI
HHHHHHHHCCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEE
TPEPEVRTGIYRTEALKPTGAGDSFMGGFVSGLTDGLSVSDAVLQGSAAAAMVVARVGCA
CCCCCHHHCEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCC
PAMPTRSELDAFLNDHPGPTAPSDPA
CCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA