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The map label for this gene is idhA [H]

Identifier: 89053907

GI number: 89053907

Start: 1384739

End: 1385725

Strand: Reverse

Name: idhA [H]

Synonym: Jann_1416

Alternate gene names: 89053907

Gene position: 1385725-1384739 (Counterclockwise)

Preceding gene: 89053908

Following gene: 89053900

Centisome position: 32.09

GC content: 58.76

Gene sequence:

>987_bases
ATGCTGAGAATTGGGCTTCTGGGGTGTGGGCGGATCGGGCAGGTCCACGGGCGGACGATCAAGGCGCTGGACAACGCACG
GGTGGTTGCGGTCGCGGACGCCGTGCCCGCGGCCGCCAGCGCCTTGGCGAGCATGTTGGGGGCAGACGTTCGCGCCGCCG
AGGAGGTGTTGTCTGCAACGGATATCGACGCCGTCGTTATTGGTACGCCGACATCCATTCACTTCGAACAAATTCGTTTG
GCAGCAAGGGGTTCCAAGGCAATCTTCTGTGAGAAACCTGTGGATATGTCTGTGGACAATATACGGAAATTGGTTGATGT
GACCGCCGAGGCCAGTGTTCCGTTCTTCACAGCATTTAACCGCCGGTTTGATCCGAACTTTGCCTCCCTCCAGACGCGTC
TCTCAGCGGGAGAAATTGGTGCGGTTGAACTGATCCAAATTACCTCGCGCGACCCCTCGCCCCCGCCAATCGGCTATATC
AAGACTTCTGGCGGGTTGTTCCGGGACATGATGATCCATGATTTCGACATGGCTCGGTTTCTGATGGGGGAGGAATTTAC
GACCCTCTCCGCCGTAGGGTCCTGCCTTGTGAACCCTGAGATCGGAGAGGCCGGTGACGTGGATACGGCCGCTGTTACGT
TGACCACCGCGTCTGGGCGGATCTGCCAGATCTCCAATTCGCGGCGCGCGAGTTATGGTTACGACCAGCGGATCGAGGTG
CATGGGTCAAAGGGTATGCTGCGAGCCGAGAATATTCTGGAGACGTCGGTGGAAATCGCCACGGCGGACGGCTTCCAGCG
CGCGCCGACGATGAACTTCTTCCTGGAACGCTATGAGGCCGCTTATACCGCTGAAATGAAAGCATTTACCGACTGCGTCT
TGACCGGCACCAAGCCGACCCCATCGATTGAAGATGGATTGCAGGCGCAGATCCTGGCGGATGCGGCGACGCTATCCCAA
CAGACCGGACAGCCTGTCGCGCTCTAG

Upstream 100 bases:

>100_bases
ATTTGACCGTATTCAGATCCTGCGCGACACCCATGAGCCGGTTTTTAACGCCGCGCGTCGCGTGTTTCGCGGGATGAATG
CCTCAGGAAAAGGGTAGGCG

Downstream 100 bases:

>100_bases
TCTTTCCTGGGCCACTTGAAAATCAAATTCCAAGCCAAGAACCCTCCGATCCCCGCAGAGAGATAGGCCCAGATCGTGTT
GCCGTAAGACATCTCAACGA

Product: myo-inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLRIGLLGCGRIGQVHGRTIKALDNARVVAVADAVPAAASALASMLGADVRAAEEVLSATDIDAVVIGTPTSIHFEQIRL
AARGSKAIFCEKPVDMSVDNIRKLVDVTAEASVPFFTAFNRRFDPNFASLQTRLSAGEIGAVELIQITSRDPSPPPIGYI
KTSGGLFRDMMIHDFDMARFLMGEEFTTLSAVGSCLVNPEIGEAGDVDTAAVTLTTASGRICQISNSRRASYGYDQRIEV
HGSKGMLRAENILETSVEIATADGFQRAPTMNFFLERYEAAYTAEMKAFTDCVLTGTKPTPSIEDGLQAQILADAATLSQ
QTGQPVAL

Sequences:

>Translated_328_residues
MLRIGLLGCGRIGQVHGRTIKALDNARVVAVADAVPAAASALASMLGADVRAAEEVLSATDIDAVVIGTPTSIHFEQIRL
AARGSKAIFCEKPVDMSVDNIRKLVDVTAEASVPFFTAFNRRFDPNFASLQTRLSAGEIGAVELIQITSRDPSPPPIGYI
KTSGGLFRDMMIHDFDMARFLMGEEFTTLSAVGSCLVNPEIGEAGDVDTAAVTLTTASGRICQISNSRRASYGYDQRIEV
HGSKGMLRAENILETSVEIATADGFQRAPTMNFFLERYEAAYTAEMKAFTDCVLTGTKPTPSIEDGLQAQILADAATLSQ
QTGQPVAL
>Mature_328_residues
MLRIGLLGCGRIGQVHGRTIKALDNARVVAVADAVPAAASALASMLGADVRAAEEVLSATDIDAVVIGTPTSIHFEQIRL
AARGSKAIFCEKPVDMSVDNIRKLVDVTAEASVPFFTAFNRRFDPNFASLQTRLSAGEIGAVELIQITSRDPSPPPIGYI
KTSGGLFRDMMIHDFDMARFLMGEEFTTLSAVGSCLVNPEIGEAGDVDTAAVTLTTASGRICQISNSRRASYGYDQRIEV
HGSKGMLRAENILETSVEIATADGFQRAPTMNFFLERYEAAYTAEMKAFTDCVLTGTKPTPSIEDGLQAQILADAATLSQ
QTGQPVAL

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=256, Percent_Identity=24.609375, Blast_Score=82, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581117, Length=265, Percent_Identity=25.2830188679245, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 34997; Mature: 34997

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIGLLGCGRIGQVHGRTIKALDNARVVAVADAVPAAASALASMLGADVRAAEEVLSAT
CEEEEEECCCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHC
DIDAVVIGTPTSIHFEQIRLAARGSKAIFCEKPVDMSVDNIRKLVDVTAEASVPFFTAFN
CCCEEEEECCCCEEHHHHHEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEHHC
RRFDPNFASLQTRLSAGEIGAVELIQITSRDPSPPPIGYIKTSGGLFRDMMIHDFDMARF
CCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
LMGEEFTTLSAVGSCLVNPEIGEAGDVDTAAVTLTTASGRICQISNSRRASYGYDQRIEV
HHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEE
HGSKGMLRAENILETSVEIATADGFQRAPTMNFFLERYEAAYTAEMKAFTDCVLTGTKPT
ECCCCCCHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
PSIEDGLQAQILADAATLSQQTGQPVAL
CCHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLRIGLLGCGRIGQVHGRTIKALDNARVVAVADAVPAAASALASMLGADVRAAEEVLSAT
CEEEEEECCCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHC
DIDAVVIGTPTSIHFEQIRLAARGSKAIFCEKPVDMSVDNIRKLVDVTAEASVPFFTAFN
CCCEEEEECCCCEEHHHHHEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEHHC
RRFDPNFASLQTRLSAGEIGAVELIQITSRDPSPPPIGYIKTSGGLFRDMMIHDFDMARF
CCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
LMGEEFTTLSAVGSCLVNPEIGEAGDVDTAAVTLTTASGRICQISNSRRASYGYDQRIEV
HHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCEEEE
HGSKGMLRAENILETSVEIATADGFQRAPTMNFFLERYEAAYTAEMKAFTDCVLTGTKPT
ECCCCCCHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
PSIEDGLQAQILADAATLSQQTGQPVAL
CCHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]