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The map label for this gene is lipB [H]

Identifier: 89053765

GI number: 89053765

Start: 1234774

End: 1235571

Strand: Reverse

Name: lipB [H]

Synonym: Jann_1274

Alternate gene names: 89053765

Gene position: 1235571-1234774 (Counterclockwise)

Preceding gene: 89053766

Following gene: 89053764

Centisome position: 28.61

GC content: 61.9

Gene sequence:

>798_bases
ATGGCTGAGTTGCGCTTCACCATCCTGGGCTGCGGCTCCTCGGGCGGTGTGCCGCGACTGGGTGGCCATTGGGGGGAATG
TGATCCGGCGAACCCGAGAAACGCACGGCGCAGATGCTCCCTCCTCGTTGAACGGGAGGGGGAAAGTGGCACGACGACGG
TGCTGATCGACACGTCACCGGACCTGCGCGCACAGCTTCTGGATGCCGGGATCGGGCGACTTGATGCGGTGCTATACACC
CACGCCCATGCCGACCATGTCCACGGGCTGGATGACCTGCGAATGATCGTCTTCAACATGCGCGCGCGCCTGCCTGTCTA
TGCGGACGGCGCGACGACGAACGACCTGCTGAACCGGTTTGGCTATGCCTTCGTGCAGCCGCCGGGCTCGGCCTATCCGC
CAATCCTCGACATCAATCACCTGGGCGGCGATGTCACGATTGACGGCGAGGGAGGATCAATTACCTTCGCCCCGTTTGAG
GTCAACCACGGCAATATCGATGCGCTTGGCTTCCGCATCGGGGACGTGGCCTACCTGCCCGATGTCTCTGCGATCCCGGA
GGATACCTGGCCGATGCTGCAAGGCCTCGACACCTGGATCCTGGACGCCCTGCGCCGCACGCCACATCCCAGCCACAGCC
ATCTGGATAATTCGCTGGCCTGGATCAAGCGAGCAAATCCGCGCCGCGCCGTGCTGACGAACATGCATATTGATCTGGAT
TATCAAACGATTGCCGACGAGACACCGGACAATGTAATCCCGGCCTATGATGGGCTGACACTGACGTATCAGGTCTGA

Upstream 100 bases:

>100_bases
GCAGCGGCGGAGACCTTTGGCGTCAGCTACGCAGACTTCGCGCGCCAGACGACCGAGAACTTCGACCGCCTGTTCTGGAA
AGCCGCACCGGGGCCCAGCA

Downstream 100 bases:

>100_bases
ATGGGCGATCTTCTGACAGTCGTCCTGCCGGTCTTCCTTGTGGTCGGTGCAGGATATGTCGCGGTGTGGCGCGGGTTGTT
TGCCGACAGCGCCGTCGATG

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAELRFTILGCGSSGGVPRLGGHWGECDPANPRNARRRCSLLVEREGESGTTTVLIDTSPDLRAQLLDAGIGRLDAVLYT
HAHADHVHGLDDLRMIVFNMRARLPVYADGATTNDLLNRFGYAFVQPPGSAYPPILDINHLGGDVTIDGEGGSITFAPFE
VNHGNIDALGFRIGDVAYLPDVSAIPEDTWPMLQGLDTWILDALRRTPHPSHSHLDNSLAWIKRANPRRAVLTNMHIDLD
YQTIADETPDNVIPAYDGLTLTYQV

Sequences:

>Translated_265_residues
MAELRFTILGCGSSGGVPRLGGHWGECDPANPRNARRRCSLLVEREGESGTTTVLIDTSPDLRAQLLDAGIGRLDAVLYT
HAHADHVHGLDDLRMIVFNMRARLPVYADGATTNDLLNRFGYAFVQPPGSAYPPILDINHLGGDVTIDGEGGSITFAPFE
VNHGNIDALGFRIGDVAYLPDVSAIPEDTWPMLQGLDTWILDALRRTPHPSHSHLDNSLAWIKRANPRRAVLTNMHIDLD
YQTIADETPDNVIPAYDGLTLTYQV
>Mature_264_residues
AELRFTILGCGSSGGVPRLGGHWGECDPANPRNARRRCSLLVEREGESGTTTVLIDTSPDLRAQLLDAGIGRLDAVLYTH
AHADHVHGLDDLRMIVFNMRARLPVYADGATTNDLLNRFGYAFVQPPGSAYPPILDINHLGGDVTIDGEGGSITFAPFEV
NHGNIDALGFRIGDVAYLPDVSAIPEDTWPMLQGLDTWILDALRRTPHPSHSHLDNSLAWIKRANPRRAVLTNMHIDLDY
QTIADETPDNVIPAYDGLTLTYQV

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 28997; Mature: 28866

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELRFTILGCGSSGGVPRLGGHWGECDPANPRNARRRCSLLVEREGESGTTTVLIDTSP
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCEEEEEECCC
DLRAQLLDAGIGRLDAVLYTHAHADHVHGLDDLRMIVFNMRARLPVYADGATTNDLLNRF
CHHHHHHHHCCCHHHHEEEECCCCHHHCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHC
GYAFVQPPGSAYPPILDINHLGGDVTIDGEGGSITFAPFEVNHGNIDALGFRIGDVAYLP
CEEEECCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEEEECCCCEEEEEEEECCEEECC
DVSAIPEDTWPMLQGLDTWILDALRRTPHPSHSHLDNSLAWIKRANPRRAVLTNMHIDLD
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHEECCCCCEEEEEEEEEEEC
YQTIADETPDNVIPAYDGLTLTYQV
HHHHCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
AELRFTILGCGSSGGVPRLGGHWGECDPANPRNARRRCSLLVEREGESGTTTVLIDTSP
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCEEEEEECCC
DLRAQLLDAGIGRLDAVLYTHAHADHVHGLDDLRMIVFNMRARLPVYADGATTNDLLNRF
CHHHHHHHHCCCHHHHEEEECCCCHHHCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHC
GYAFVQPPGSAYPPILDINHLGGDVTIDGEGGSITFAPFEVNHGNIDALGFRIGDVAYLP
CEEEECCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEEEECCCCEEEEEEEECCEEECC
DVSAIPEDTWPMLQGLDTWILDALRRTPHPSHSHLDNSLAWIKRANPRRAVLTNMHIDLD
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHEECCCCCEEEEEEEEEEEC
YQTIADETPDNVIPAYDGLTLTYQV
HHHHCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]