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The map label for this gene is ctaDII [H]

Identifier: 89053740

GI number: 89053740

Start: 1204165

End: 1204632

Strand: Reverse

Name: ctaDII [H]

Synonym: Jann_1249

Alternate gene names: 89053740

Gene position: 1204632-1204165 (Counterclockwise)

Preceding gene: 89053741

Following gene: 89053739

Centisome position: 27.9

GC content: 66.03

Gene sequence:

>468_bases
ATGCGCTGGTATGACTGGCTGATCCTGACAACGATAGGCGCCCTCCTCGGGGGCGCCTATTTTCGATTCTGGCCCTCGCA
GCGGATCGCCCTGAGCCAGCCCGGAGCAGATGGCACCTACCACGACACCTACTACGTGGTGGCCCACATCCACTACCTTG
GCCTTCTGGCGCTTCTTGTTGTGGCCGTCGGGACCGCCTACGTCCTGTTGCTCCGCCGGTCCGTGCCGCGCATCGCCGTG
TCCGGGGCCGTTGCGATCTGCATGCTCTGCCTGGGAACCGCGTTCATGGTCGCGCCTCAGGCCGTCCTGCCGGGCGGTGG
CATGCCGCGCCGCTACACGGATTACGCGGACGCGGTCGAGCGCTGGCAGATGCTCTCCGCCATCGGCGCAAGCCTCGCCA
TCGCGGCGCTTGTTACGCTACTGGTTTTGACGATCCGGGCGCTGCTCCTCCGCAGGCGCTCCAAATAA

Upstream 100 bases:

>100_bases
CGCTGGAATGGACCCTGCCCAACCCGCCCCCGGAGCACACGTTTGAGGAGCTTCCCACCCGCGAGATGTGGGACAAGCAA
CCGGGTCACTGACCACTGTC

Downstream 100 bases:

>100_bases
CCGACCGCGACGGCTTGCCACTTGCCGCGCCGCCCGTTCGGCGCATGATACCTCTTATGCCGATCACGACCGAAACACCC
GACGTCCCCTCGCCCACACG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-beta; Cytochrome c oxidase polypeptide I-beta [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRWYDWLILTTIGALLGGAYFRFWPSQRIALSQPGADGTYHDTYYVVAHIHYLGLLALLVVAVGTAYVLLLRRSVPRIAV
SGAVAICMLCLGTAFMVAPQAVLPGGGMPRRYTDYADAVERWQMLSAIGASLAIAALVTLLVLTIRALLLRRRSK

Sequences:

>Translated_155_residues
MRWYDWLILTTIGALLGGAYFRFWPSQRIALSQPGADGTYHDTYYVVAHIHYLGLLALLVVAVGTAYVLLLRRSVPRIAV
SGAVAICMLCLGTAFMVAPQAVLPGGGMPRRYTDYADAVERWQMLSAIGASLAIAALVTLLVLTIRALLLRRRSK
>Mature_155_residues
MRWYDWLILTTIGALLGGAYFRFWPSQRIALSQPGADGTYHDTYYVVAHIHYLGLLALLVVAVGTAYVLLLRRSVPRIAV
SGAVAICMLCLGTAFMVAPQAVLPGGGMPRRYTDYADAVERWQMLSAIGASLAIAALVTLLVLTIRALLLRRRSK

Specific function: Subunit I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). This cytochrome c oxidase shows proton pump activity across th

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=148, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 16965; Mature: 16965

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWYDWLILTTIGALLGGAYFRFWPSQRIALSQPGADGTYHDTYYVVAHIHYLGLLALLV
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VAVGTAYVLLLRRSVPRIAVSGAVAICMLCLGTAFMVAPQAVLPGGGMPRRYTDYADAVE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHH
RWQMLSAIGASLAIAALVTLLVLTIRALLLRRRSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRWYDWLILTTIGALLGGAYFRFWPSQRIALSQPGADGTYHDTYYVVAHIHYLGLLALLV
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VAVGTAYVLLLRRSVPRIAVSGAVAICMLCLGTAFMVAPQAVLPGGGMPRRYTDYADAVE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHH
RWQMLSAIGASLAIAALVTLLVLTIRALLLRRRSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2155830; 7651515; 9380672; 10338009; 8794157 [H]