Click here to switch to the map view.

The map label for this gene is atzB [H]

Identifier: 89053725

GI number: 89053725

Start: 1189676

End: 1191016

Strand: Direct

Name: atzB [H]

Synonym: Jann_1234

Alternate gene names: 89053725

Gene position: 1189676-1191016 (Clockwise)

Preceding gene: 89053724

Following gene: 89053726

Centisome position: 27.55

GC content: 65.4

Gene sequence:

>1341_bases
ATGACTGATCTGGTCCTGCGCAACGTCGCCCATTGCCTGACGATGGATGACGCGGGGACCGAGCCGCGCGACGTCGATAT
CCTGTTGCGGGATGGGCAGATTTCTGAATTTGGCCAAAGCCTTGCGACCGAAGCTTCATCTATTGATTGCAGCGCGTGTC
TGGTGACGCCGGGCCTCGTGAACACCCACCACCACCTGTTTCAGACGCTCACCCGCGCCGTGCCCGGAGCCCAGGATGCG
GCGCTTTTTGGCTGGCTGCAGACGCTCTATCCGATCTGGTCCCGCTTCACCCCGGATCATATGGAAACCTCGGCGATCAT
CGGTCTGGCAGAGCTGGCGCTGTCGGGCTGCACGACGTCCTCGGATCATATGTATCTGTTCCCGAACGGCTCCCGCCTTG
ATGATACTATCGCGGCGGCGCAGCAGGTCGGCCTGCGGTTTCATCCCACGCGTGGGGCGATGTCTATCGGCGTCTCGGAC
GGCGGCCTGCCCCCTGACGCGCTGGTGGAAGATGAGGTCGCCATTCTGGAAGATTGCCTGCGCGTTATCGATGCCTTCCA
TGATCCCGCGCCCGGCTCGATGTGTCAGGTCGGCGTGGCGCCCTGTTCGCCCTTCTCGGTGAGTCGCGAGTTGATGCGCG
ATGCCGCCATCCTCGCCCGCGACAAGGGGGTGATGCTGCACACGCATCTGGCTGAAAACGATGAAGATATCGCCTATTCC
TTGGAAAAGTTCGGCTGCCGTCCCGGGCAATATGCCGAGGATCTGGGCTGGACCGGCGATGACGTGTGGCATGCCCATTG
CGTGAAACTGGACGGGCAGGAGATTGATCTGTTCGCCCGTTCCGGCACCGGTGTTGCCCATTGCCCCTGCTCCAATTGTC
GTCTCGCCTCCGGTATCGCGCCGGTGCGGGCCATGCGGGACGCGGGCGTGACGGTCGGCCTTGGCGTGGATGGATCGGCG
TCCAACGACGCGGGGTCCCTGGTGGATGAGGCGCGGCAAGCGATGCTTTTGCAGCGCGTGGTCAGCGGCCCCGATGCGAT
GTCCGCGCGGGAGGCGTTGCGTATCGCCACCCGTGGCGGGGCAGAGGTGTTGGGCCGGGGTCAGGAGTTGGGTCAGATCG
CGCCGGGGTTCCGGGCCGATCTGGCGATCTGGGACATGTCGGGTGTGGAGGCTGCGGGCAGTTGGGACCCCGCGGCCCTC
CTGCTGGCCGGGCCGCGCCGGGTGCGCGACCTGATCGTGGAGGGACGCGTGGTGGTGCGCGACGGGCAGATGGCAGTGCT
GGATCTCGCGCCGCATTTGGCCCGCCAACGGCAGTTTGCGCGGGCGCTTGCTGACGGCTGA

Upstream 100 bases:

>100_bases
AATTGGGAGGGCGGGCCGGTCCATGACGGGGGACGCGCGATCGCCGCCGCCTCGCCCGCGCTACATGCCGAGGCGATGGC
CTTGGTGAAAGGTACAGTAG

Downstream 100 bases:

>100_bases
AACTTGTCTTTTTCAGATAATTTTAGTCAAATTGTCGCCGTAATGCGCCAGTAATCTATTATTCACTACATCGACTAAAA
CTTCTTCCACAGGGCCGTGC

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTDLVLRNVAHCLTMDDAGTEPRDVDILLRDGQISEFGQSLATEASSIDCSACLVTPGLVNTHHHLFQTLTRAVPGAQDA
ALFGWLQTLYPIWSRFTPDHMETSAIIGLAELALSGCTTSSDHMYLFPNGSRLDDTIAAAQQVGLRFHPTRGAMSIGVSD
GGLPPDALVEDEVAILEDCLRVIDAFHDPAPGSMCQVGVAPCSPFSVSRELMRDAAILARDKGVMLHTHLAENDEDIAYS
LEKFGCRPGQYAEDLGWTGDDVWHAHCVKLDGQEIDLFARSGTGVAHCPCSNCRLASGIAPVRAMRDAGVTVGLGVDGSA
SNDAGSLVDEARQAMLLQRVVSGPDAMSAREALRIATRGGAEVLGRGQELGQIAPGFRADLAIWDMSGVEAAGSWDPAAL
LLAGPRRVRDLIVEGRVVVRDGQMAVLDLAPHLARQRQFARALADG

Sequences:

>Translated_446_residues
MTDLVLRNVAHCLTMDDAGTEPRDVDILLRDGQISEFGQSLATEASSIDCSACLVTPGLVNTHHHLFQTLTRAVPGAQDA
ALFGWLQTLYPIWSRFTPDHMETSAIIGLAELALSGCTTSSDHMYLFPNGSRLDDTIAAAQQVGLRFHPTRGAMSIGVSD
GGLPPDALVEDEVAILEDCLRVIDAFHDPAPGSMCQVGVAPCSPFSVSRELMRDAAILARDKGVMLHTHLAENDEDIAYS
LEKFGCRPGQYAEDLGWTGDDVWHAHCVKLDGQEIDLFARSGTGVAHCPCSNCRLASGIAPVRAMRDAGVTVGLGVDGSA
SNDAGSLVDEARQAMLLQRVVSGPDAMSAREALRIATRGGAEVLGRGQELGQIAPGFRADLAIWDMSGVEAAGSWDPAAL
LLAGPRRVRDLIVEGRVVVRDGQMAVLDLAPHLARQRQFARALADG
>Mature_445_residues
TDLVLRNVAHCLTMDDAGTEPRDVDILLRDGQISEFGQSLATEASSIDCSACLVTPGLVNTHHHLFQTLTRAVPGAQDAA
LFGWLQTLYPIWSRFTPDHMETSAIIGLAELALSGCTTSSDHMYLFPNGSRLDDTIAAAQQVGLRFHPTRGAMSIGVSDG
GLPPDALVEDEVAILEDCLRVIDAFHDPAPGSMCQVGVAPCSPFSVSRELMRDAAILARDKGVMLHTHLAENDEDIAYSL
EKFGCRPGQYAEDLGWTGDDVWHAHCVKLDGQEIDLFARSGTGVAHCPCSNCRLASGIAPVRAMRDAGVTVGLGVDGSAS
NDAGSLVDEARQAMLLQRVVSGPDAMSAREALRIATRGGAEVLGRGQELGQIAPGFRADLAIWDMSGVEAAGSWDPAALL
LAGPRRVRDLIVEGRVVVRDGQMAVLDLAPHLARQRQFARALADG

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=339, Percent_Identity=24.7787610619469, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1789249, Length=369, Percent_Identity=24.9322493224932, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319963, Length=339, Percent_Identity=28.3185840707965, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24643849, Length=355, Percent_Identity=25.0704225352113, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 47478; Mature: 47347

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLVLRNVAHCLTMDDAGTEPRDVDILLRDGQISEFGQSLATEASSIDCSACLVTPGLV
CCHHHHHHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCH
NTHHHLFQTLTRAVPGAQDAALFGWLQTLYPIWSRFTPDHMETSAIIGLAELALSGCTTS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
SDHMYLFPNGSRLDDTIAAAQQVGLRFHPTRGAMSIGVSDGGLPPDALVEDEVAILEDCL
CCEEEECCCCCCCHHHHHHHHHCCCEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
RVIDAFHDPAPGSMCQVGVAPCSPFSVSRELMRDAAILARDKGVMLHTHLAENDEDIAYS
HHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
LEKFGCRPGQYAEDLGWTGDDVWHAHCVKLDGQEIDLFARSGTGVAHCPCSNCRLASGIA
HHHHCCCCCCCHHHCCCCCCCCCEEEEEEECCCEEEEEEECCCCEEECCCCCCCHHCCCH
PVRAMRDAGVTVGLGVDGSASNDAGSLVDEARQAMLLQRVVSGPDAMSAREALRIATRGG
HHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
AEVLGRGQELGQIAPGFRADLAIWDMSGVEAAGSWDPAALLLAGPRRVRDLIVEGRVVVR
HHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHCCEEEEE
DGQMAVLDLAPHLARQRQFARALADG
CCCEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDLVLRNVAHCLTMDDAGTEPRDVDILLRDGQISEFGQSLATEASSIDCSACLVTPGLV
CHHHHHHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCH
NTHHHLFQTLTRAVPGAQDAALFGWLQTLYPIWSRFTPDHMETSAIIGLAELALSGCTTS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
SDHMYLFPNGSRLDDTIAAAQQVGLRFHPTRGAMSIGVSDGGLPPDALVEDEVAILEDCL
CCEEEECCCCCCCHHHHHHHHHCCCEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
RVIDAFHDPAPGSMCQVGVAPCSPFSVSRELMRDAAILARDKGVMLHTHLAENDEDIAYS
HHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
LEKFGCRPGQYAEDLGWTGDDVWHAHCVKLDGQEIDLFARSGTGVAHCPCSNCRLASGIA
HHHHCCCCCCCHHHCCCCCCCCCEEEEEEECCCEEEEEEECCCCEEECCCCCCCHHCCCH
PVRAMRDAGVTVGLGVDGSASNDAGSLVDEARQAMLLQRVVSGPDAMSAREALRIATRGG
HHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
AEVLGRGQELGQIAPGFRADLAIWDMSGVEAAGSWDPAALLLAGPRRVRDLIVEGRVVVR
HHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHCCEEEEE
DGQMAVLDLAPHLARQRQFARALADG
CCCEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]