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The map label for this gene is qor [H]

Identifier: 89053722

GI number: 89053722

Start: 1187258

End: 1188217

Strand: Reverse

Name: qor [H]

Synonym: Jann_1231

Alternate gene names: 89053722

Gene position: 1188217-1187258 (Counterclockwise)

Preceding gene: 89053727

Following gene: 89053720

Centisome position: 27.52

GC content: 66.25

Gene sequence:

>960_bases
ATGCGAGCATTTGTGGTAAGCGATCATGGGGTGCCCCCCCGTGTCGAAGAAGTGGCAGAGCCCACGCCCGGCCCGGGACA
GGTGCGCATACGGATCCACGCCTGCGGGGTGAATTTCGGCGATTTGTTGATCGTGAAAGGCACCTATCAGGACACGCCGG
CCCTGCCCTTCACCCTTGGGATGGAGATCGCGGGCGTGGTGGACGCGTTGGGCGACGGCGTCACGTCGCCTGCATTGGGC
ACACGCGTGGCAGTGTTCGAGGGCTCTGGCGGGATGGCGGAGTTCGGCGTCTTCAGCGCGACCCGCTGCGTGGAGATCCC
CGATACGATGCCGTTTGAGGAGGCCGCGGGATTCATCGTGGCCTACGGGACCTCCCACCTCGCGCTGACAGACCGCGCGC
ATCTGAAACAGGGCGAGCGTCTATTGGTTCTGGGTGCAGCCGGGGGCGTCGGCCTGACGGCGGTGGAACTGGGGGCGGCG
ATGGGGGCCGAGGTCATCGCGGTCGCACGGGGCGCTGAGAAACTGGCTGTGGCAAAGGCCGCCGGGGCCGCCCACGTGCT
GGACAGTGAAACGTCCGACATCCGCGCCGAGGTGAAGGCGCTTGGCGGAGCTGATGTGGTCTATGACGCCGTGGGCGGCG
ATGGGTTCAAGGCGGCCATGCGGGCCACAAACCCCGGCGGCCGGATCATCGTCATCGGCTTCGCCAGCGGCGACGTGCCC
CAGATCCCGGCCAATCATCTGTTGGTCAAGAACATCGACGCCATTGGCTTTTACTGGGGCGGGTATCTGAAATGGGCACC
CGAACGTCTCGCGCAAAGCTTGTCGGACCTGATGGCCATGTATGAGGCAGGGCAGCTGAGCCCGCATATCGGCGCGACGC
GGCCCTTGGCGGAGGCGGGCGACGCGCTGGAGTTGCTGCGCTCCCGCAAAGTCGCGGGGAAGGTCGTCGTGACGATCTAG

Upstream 100 bases:

>100_bases
TAGCAGTTCAATGGGAGGTTGTGTGAAAAAAGCACGCGGCTGGCGGAAGCGGTGGCGAGCCGCTAGGACGAGACGGAGAG
ATCCAGCGGCGGAGGCGGAC

Downstream 100 bases:

>100_bases
GTGCAGCGATAGGTCTAGATGGAGCGGTAGGCCTGGCGGATCAGATCGACAAGGGCATCTACAGGCTCGGCCCGGGACAG
GTCTGAGCGGTACATGTTGA

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRAFVVSDHGVPPRVEEVAEPTPGPGQVRIRIHACGVNFGDLLIVKGTYQDTPALPFTLGMEIAGVVDALGDGVTSPALG
TRVAVFEGSGGMAEFGVFSATRCVEIPDTMPFEEAAGFIVAYGTSHLALTDRAHLKQGERLLVLGAAGGVGLTAVELGAA
MGAEVIAVARGAEKLAVAKAAGAAHVLDSETSDIRAEVKALGGADVVYDAVGGDGFKAAMRATNPGGRIIVIGFASGDVP
QIPANHLLVKNIDAIGFYWGGYLKWAPERLAQSLSDLMAMYEAGQLSPHIGATRPLAEAGDALELLRSRKVAGKVVVTI

Sequences:

>Translated_319_residues
MRAFVVSDHGVPPRVEEVAEPTPGPGQVRIRIHACGVNFGDLLIVKGTYQDTPALPFTLGMEIAGVVDALGDGVTSPALG
TRVAVFEGSGGMAEFGVFSATRCVEIPDTMPFEEAAGFIVAYGTSHLALTDRAHLKQGERLLVLGAAGGVGLTAVELGAA
MGAEVIAVARGAEKLAVAKAAGAAHVLDSETSDIRAEVKALGGADVVYDAVGGDGFKAAMRATNPGGRIIVIGFASGDVP
QIPANHLLVKNIDAIGFYWGGYLKWAPERLAQSLSDLMAMYEAGQLSPHIGATRPLAEAGDALELLRSRKVAGKVVVTI
>Mature_319_residues
MRAFVVSDHGVPPRVEEVAEPTPGPGQVRIRIHACGVNFGDLLIVKGTYQDTPALPFTLGMEIAGVVDALGDGVTSPALG
TRVAVFEGSGGMAEFGVFSATRCVEIPDTMPFEEAAGFIVAYGTSHLALTDRAHLKQGERLLVLGAAGGVGLTAVELGAA
MGAEVIAVARGAEKLAVAKAAGAAHVLDSETSDIRAEVKALGGADVVYDAVGGDGFKAAMRATNPGGRIIVIGFASGDVP
QIPANHLLVKNIDAIGFYWGGYLKWAPERLAQSLSDLMAMYEAGQLSPHIGATRPLAEAGDALELLRSRKVAGKVVVTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=33.3333333333333, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=30.2752293577982, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=30.2752293577982, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=26.3610315186246, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI194239676, Length=324, Percent_Identity=28.3950617283951, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI28557745, Length=316, Percent_Identity=30.379746835443, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI67078404, Length=331, Percent_Identity=25.3776435045317, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI22538446, Length=314, Percent_Identity=24.8407643312102, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI22538444, Length=314, Percent_Identity=24.8407643312102, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI67078406, Length=295, Percent_Identity=25.0847457627119, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI41872631, Length=333, Percent_Identity=26.7267267267267, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1790485, Length=314, Percent_Identity=28.9808917197452, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787863, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081918, Length=361, Percent_Identity=24.9307479224377, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI226510941, Length=243, Percent_Identity=28.8065843621399, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=325, Percent_Identity=29.2307692307692, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536829, Length=319, Percent_Identity=25.0783699059561, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=314, Percent_Identity=30.8917197452229, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323961, Length=277, Percent_Identity=24.5487364620939, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=279, Percent_Identity=24.7311827956989, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45550423, Length=314, Percent_Identity=25.4777070063694, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 32849; Mature: 32849

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFVVSDHGVPPRVEEVAEPTPGPGQVRIRIHACGVNFGDLLIVKGTYQDTPALPFTLG
CEEEEEECCCCCCCHHHHCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCEEEC
MEIAGVVDALGDGVTSPALGTRVAVFEGSGGMAEFGVFSATRCVEIPDTMPFEEAAGFIV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCEEEECCCCCCHHHHCCEEE
AYGTSHLALTDRAHLKQGERLLVLGAAGGVGLTAVELGAAMGAEVIAVARGAEKLAVAKA
EECCCEEEEECHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHH
AGAAHVLDSETSDIRAEVKALGGADVVYDAVGGDGFKAAMRATNPGGRIIVIGFASGDVP
CCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCHHHEEECCCCCEEEEEEECCCCCC
QIPANHLLVKNIDAIGFYWGGYLKWAPERLAQSLSDLMAMYEAGQLSPHIGATRPLAEAG
CCCCCCEEEECCCEEEEEECCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCC
DALELLRSRKVAGKVVVTI
HHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MRAFVVSDHGVPPRVEEVAEPTPGPGQVRIRIHACGVNFGDLLIVKGTYQDTPALPFTLG
CEEEEEECCCCCCCHHHHCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCEEEC
MEIAGVVDALGDGVTSPALGTRVAVFEGSGGMAEFGVFSATRCVEIPDTMPFEEAAGFIV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCEEEECCCCCCHHHHCCEEE
AYGTSHLALTDRAHLKQGERLLVLGAAGGVGLTAVELGAAMGAEVIAVARGAEKLAVAKA
EECCCEEEEECHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHH
AGAAHVLDSETSDIRAEVKALGGADVVYDAVGGDGFKAAMRATNPGGRIIVIGFASGDVP
CCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCHHHEEECCCCCEEEEEEECCCCCC
QIPANHLLVKNIDAIGFYWGGYLKWAPERLAQSLSDLMAMYEAGQLSPHIGATRPLAEAG
CCCCCCEEEECCCEEEEEECCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCC
DALELLRSRKVAGKVVVTI
HHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]