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The map label for this gene is yciL [C]

Identifier: 89053708

GI number: 89053708

Start: 1176684

End: 1177574

Strand: Reverse

Name: yciL [C]

Synonym: Jann_1217

Alternate gene names: 89053708

Gene position: 1177574-1176684 (Counterclockwise)

Preceding gene: 89053710

Following gene: 89053704

Centisome position: 27.27

GC content: 63.64

Gene sequence:

>891_bases
ATGGTTGATGGTGAACGAATAGCAAAGCGGCTGAGCCGTGCGGGCGTGGCCTCGCGGCGGGAAGCGGAACGGATGATCGA
GGCCGGGCGTGTGAGCGTCAACGGTGCGGTGATCGAGAGCCCGGCGTTGAACGTGACCGACGCCGATGTGATTGAGGTCG
ACAACGCCCCCCTGCCCGAAATCGAGCGGCCCCGCGTGTGGATGTATCACAAGCCCACCGGGCTGGTGACCAGCAATGCC
GACGAGAAGGGCCGCGAAACAGTCTTCGACAAGCTGCCCGACAGCTTGCCGCGGGTGATGTCTGTGGGGCGGCTCGATAT
GAACTCCGAAGGGCTTTTGTTGCTGACCAATGACGGCGGGGTGAAGCGGAAGCTGGAATTGCCCTCAACGGGCTGGTTAC
GCAAATACCGCGTGCGCATGAAGGGCGCGCCCAAGGACGAGGATTTTGCGCCTCTGCGGCGGGGAATTGTGGCGGAGGGG
GAGCGGTTTCAGCCGATGGAGGTCTCGCTTGACCGCGTTCAGGGGGCAAATGCCTGGATCACGGTAGGCTTGCGCGAAGG
CAAAAATCGGGAGATCCGCCGCGCCATGGCGGAACTGGGGTTCGAGGTGAACCGATTGATTCGTGTCTCTTACGGCCCGT
TCCGGTTGGGTGAGCTAAAGCCGGGCGAGGTGGAAGAAGTCCGCCCCCGTGTCCTGCGCGATCAACTGGGGTTGGAGGCT
GCGACAGAGGGCCATGCGGAACCGAAGGCCAAGCCAGCATTCAAAGGCAAGCGTCGCAAGGCGCCGGACGCCCGGAAAAG
CGGTGAACGGTTGGCCCCTCGGGGCAAGCCAAGCGGTGCGGTTAGGTCGGATCGCCGGGGGTCTGGTCGTCCTCCTCGTC
GGAAAGACTGA

Upstream 100 bases:

>100_bases
GCGTGCCTGATCTAGGGCAGCTTCCATGAATGAGGTGAATTGGGTCATGGGCCCTTTGGTTGCCGCTTTCCATGGCGCTG
TCAAACTTGTAGCGAGGGGC

Downstream 100 bases:

>100_bases
ACCGCTCGATCAGGGGCGCTTGTGACATGAAGACCACGAACAGGAAGGCCGGGAGGGCAAACGTCTCGAACGTCACCCAA
AACTGGTCCGACTGGGTCCG

Product: pseudouridine synthase, Rsu

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MVDGERIAKRLSRAGVASRREAERMIEAGRVSVNGAVIESPALNVTDADVIEVDNAPLPEIERPRVWMYHKPTGLVTSNA
DEKGRETVFDKLPDSLPRVMSVGRLDMNSEGLLLLTNDGGVKRKLELPSTGWLRKYRVRMKGAPKDEDFAPLRRGIVAEG
ERFQPMEVSLDRVQGANAWITVGLREGKNREIRRAMAELGFEVNRLIRVSYGPFRLGELKPGEVEEVRPRVLRDQLGLEA
ATEGHAEPKAKPAFKGKRRKAPDARKSGERLAPRGKPSGAVRSDRRGSGRPPRRKD

Sequences:

>Translated_296_residues
MVDGERIAKRLSRAGVASRREAERMIEAGRVSVNGAVIESPALNVTDADVIEVDNAPLPEIERPRVWMYHKPTGLVTSNA
DEKGRETVFDKLPDSLPRVMSVGRLDMNSEGLLLLTNDGGVKRKLELPSTGWLRKYRVRMKGAPKDEDFAPLRRGIVAEG
ERFQPMEVSLDRVQGANAWITVGLREGKNREIRRAMAELGFEVNRLIRVSYGPFRLGELKPGEVEEVRPRVLRDQLGLEA
ATEGHAEPKAKPAFKGKRRKAPDARKSGERLAPRGKPSGAVRSDRRGSGRPPRRKD
>Mature_296_residues
MVDGERIAKRLSRAGVASRREAERMIEAGRVSVNGAVIESPALNVTDADVIEVDNAPLPEIERPRVWMYHKPTGLVTSNA
DEKGRETVFDKLPDSLPRVMSVGRLDMNSEGLLLLTNDGGVKRKLELPSTGWLRKYRVRMKGAPKDEDFAPLRRGIVAEG
ERFQPMEVSLDRVQGANAWITVGLREGKNREIRRAMAELGFEVNRLIRVSYGPFRLGELKPGEVEEVRPRVLRDQLGLEA
ATEGHAEPKAKPAFKGKRRKAPDARKSGERLAPRGKPSGAVRSDRRGSGRPPRRKD

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=221, Percent_Identity=40.2714932126697, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=32.6086956521739, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790453, Length=291, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788510, Length=220, Percent_Identity=26.8181818181818, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 32963; Mature: 32963

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDGERIAKRLSRAGVASRREAERMIEAGRVSVNGAVIESPALNVTDADVIEVDNAPLPE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEECCEEEECCCCCCCCCCEEEECCCCCCC
IERPRVWMYHKPTGLVTSNADEKGRETVFDKLPDSLPRVMSVGRLDMNSEGLLLLTNDGG
CCCCEEEEEECCCCCEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCC
VKRKLELPSTGWLRKYRVRMKGAPKDEDFAPLRRGIVAEGERFQPMEVSLDRVQGANAWI
CEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHCHHCCCCCCCCHHHHHHHHCCCCEEE
TVGLREGKNREIRRAMAELGFEVNRLIRVSYGPFRLGELKPGEVEEVRPRVLRDQLGLEA
EEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHCCHH
ATEGHAEPKAKPAFKGKRRKAPDARKSGERLAPRGKPSGAVRSDRRGSGRPPRRKD
HCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVDGERIAKRLSRAGVASRREAERMIEAGRVSVNGAVIESPALNVTDADVIEVDNAPLPE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEECCEEEECCCCCCCCCCEEEECCCCCCC
IERPRVWMYHKPTGLVTSNADEKGRETVFDKLPDSLPRVMSVGRLDMNSEGLLLLTNDGG
CCCCEEEEEECCCCCEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCC
VKRKLELPSTGWLRKYRVRMKGAPKDEDFAPLRRGIVAEGERFQPMEVSLDRVQGANAWI
CEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHCHHCCCCCCCCHHHHHHHHCCCCEEE
TVGLREGKNREIRRAMAELGFEVNRLIRVSYGPFRLGELKPGEVEEVRPRVLRDQLGLEA
EEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHCCHH
ATEGHAEPKAKPAFKGKRRKAPDARKSGERLAPRGKPSGAVRSDRRGSGRPPRRKD
HCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA