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The map label for this gene is appC [H]

Identifier: 89053565

GI number: 89053565

Start: 1035385

End: 1036236

Strand: Reverse

Name: appC [H]

Synonym: Jann_1074

Alternate gene names: 89053565

Gene position: 1036236-1035385 (Counterclockwise)

Preceding gene: 89053566

Following gene: 89053564

Centisome position: 24.0

GC content: 66.31

Gene sequence:

>852_bases
ATGACGGACAGCACCCAGCCCCTCCGCGTCGGCCCCGCGATCCCGCTCAGCGTCAAACTCGCATTGGGGTTCGTGGGGAT
CTTCGTGCTGTTCGCCCTGTTCGGTCATCTGCTGACGCCCCACGGGTTCCGCGAAACGTCGCTCATGCACCGGTTGGAGC
CGCCCGGCACCGACGGCTACCTGCTCGGCACGGATGCCCGGGGGCGGGACCTCTTCGCCCGTCTGGTGACCGGGGCGCAG
ATCACCCTGGTCGTGGCCATCGTGGGCACCGTGATCGGGGCGGCTCTCGGCTCACTTCTGGGGATCGTGGCCGCCGCCCA
ACGGGGCCGGACCGAAGCCGTGATCGTGGCGGCCATTGATGTGCAGGCGTCCCTGCCGATCATCATCGTCGCGCTCTTCA
TGCTGGCGATGTTCGACAATTCCTTCACGCTGTTCCTGCTTCTTGTCGGCCTCAATGGGTGGGAGGTTTATGCCCGCCTT
ATGCGCGGGGCGACGCTACAGGCCAAGGAATCCGGCTATGTCACCGCCGTCCGCGCCCTGGGGGCCACGCCTGCGCGGAT
CTACCTGCGCCACGTCCTGCCCAACATCCTCAACATCGCGCTGGTGCAGTTCACCGTGAACCTGCCCCTGACTATCCTGC
TGGAAACCGCCCTGTCGTTTCTGGGCCTTGGCGTGCAGCCGCCCCTGACCAGTCTGGGTCAGATCATGTCCGAGGGGCGC
GACCGCCTGATGACCGCCTGGTGGCTGACCCTTCTTCCCGGCGCGATCATCTTCTGCCTCGCGCTCTCGGTCTCGATGAT
CGGCGACTGGCTGCGCGACCGGCTTGACCCGACGTTGCGGAGTGAACGATGA

Upstream 100 bases:

>100_bases
AGGTGCAGTTTCTGGTGCTGGTCGTGGCCTTCACGATGGTCATGGCCAACCTGATCGTCGACCTGCTGTACCTTGTGATT
GATCCAAGGATCCGGGCGAA

Downstream 100 bases:

>100_bases
CCTCACCACTGCCTTCCCCTCCCAAATATACCATCGGCCCTGCGCCCGCCGCACTGGACCCCGCCCTCATCGACACCCTG
CGGCAATGCGAAACGACGAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTDSTQPLRVGPAIPLSVKLALGFVGIFVLFALFGHLLTPHGFRETSLMHRLEPPGTDGYLLGTDARGRDLFARLVTGAQ
ITLVVAIVGTVIGAALGSLLGIVAAAQRGRTEAVIVAAIDVQASLPIIIVALFMLAMFDNSFTLFLLLVGLNGWEVYARL
MRGATLQAKESGYVTAVRALGATPARIYLRHVLPNILNIALVQFTVNLPLTILLETALSFLGLGVQPPLTSLGQIMSEGR
DRLMTAWWLTLLPGAIIFCLALSVSMIGDWLRDRLDPTLRSER

Sequences:

>Translated_283_residues
MTDSTQPLRVGPAIPLSVKLALGFVGIFVLFALFGHLLTPHGFRETSLMHRLEPPGTDGYLLGTDARGRDLFARLVTGAQ
ITLVVAIVGTVIGAALGSLLGIVAAAQRGRTEAVIVAAIDVQASLPIIIVALFMLAMFDNSFTLFLLLVGLNGWEVYARL
MRGATLQAKESGYVTAVRALGATPARIYLRHVLPNILNIALVQFTVNLPLTILLETALSFLGLGVQPPLTSLGQIMSEGR
DRLMTAWWLTLLPGAIIFCLALSVSMIGDWLRDRLDPTLRSER
>Mature_282_residues
TDSTQPLRVGPAIPLSVKLALGFVGIFVLFALFGHLLTPHGFRETSLMHRLEPPGTDGYLLGTDARGRDLFARLVTGAQI
TLVVAIVGTVIGAALGSLLGIVAAAQRGRTEAVIVAAIDVQASLPIIIVALFMLAMFDNSFTLFLLLVGLNGWEVYARLM
RGATLQAKESGYVTAVRALGATPARIYLRHVLPNILNIALVQFTVNLPLTILLETALSFLGLGVQPPLTSLGQIMSEGRD
RLMTAWWLTLLPGAIIFCLALSVSMIGDWLRDRLDPTLRSER

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=257, Percent_Identity=31.9066147859922, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787760, Length=264, Percent_Identity=32.1969696969697, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787498, Length=252, Percent_Identity=30.952380952381, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789964, Length=255, Percent_Identity=33.7254901960784, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=28.2786885245902, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787549, Length=255, Percent_Identity=31.7647058823529, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788505, Length=228, Percent_Identity=28.5087719298246, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30466; Mature: 30335

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTQPLRVGPAIPLSVKLALGFVGIFVLFALFGHLLTPHGFRETSLMHRLEPPGTDGY
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCE
LLGTDARGRDLFARLVTGAQITLVVAIVGTVIGAALGSLLGIVAAAQRGRTEAVIVAAID
EEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
VQASLPIIIVALFMLAMFDNSFTLFLLLVGLNGWEVYARLMRGATLQAKESGYVTAVRAL
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCHHHHHHHH
GATPARIYLRHVLPNILNIALVQFTVNLPLTILLETALSFLGLGVQPPLTSLGQIMSEGR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DRLMTAWWLTLLPGAIIFCLALSVSMIGDWLRDRLDPTLRSER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
TDSTQPLRVGPAIPLSVKLALGFVGIFVLFALFGHLLTPHGFRETSLMHRLEPPGTDGY
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCE
LLGTDARGRDLFARLVTGAQITLVVAIVGTVIGAALGSLLGIVAAAQRGRTEAVIVAAID
EEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
VQASLPIIIVALFMLAMFDNSFTLFLLLVGLNGWEVYARLMRGATLQAKESGYVTAVRAL
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCHHHHHHHH
GATPARIYLRHVLPNILNIALVQFTVNLPLTILLETALSFLGLGVQPPLTSLGQIMSEGR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DRLMTAWWLTLLPGAIIFCLALSVSMIGDWLRDRLDPTLRSER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]