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The map label for this gene is clpA [C]

Identifier: 89053532

GI number: 89053532

Start: 995874

End: 998231

Strand: Reverse

Name: clpA [C]

Synonym: Jann_1041

Alternate gene names: 89053532

Gene position: 998231-995874 (Counterclockwise)

Preceding gene: 89053533

Following gene: 89053528

Centisome position: 23.12

GC content: 59.8

Gene sequence:

>2358_bases
ATGCAGACGAAAGGAGCACAGATAGTGCCGTCTTTTTCGAACACACTGGAACAGGCCATCCACGCCGCGCTGGCCAACGC
CAACGCGCGTCGTCATGAATTGGCGACCCTGGAACACCTGCTTCTTGCACTCATTGATGAGCCCGACGCACAAAAGGTCA
TGAAGGCCTGCTCGGTCGATATCGAAGTGTTGCGGGACACCCTGTCGAAGTTCATCGATGATGATCTTTCGACACTTGAA
ACGGATGTCGAAGGATCGGAGGCTGTACCAACGGCCGCCTTCCAGCGCGTGATCCAACGCGCCGCCATTCACGTTCAATC
CTCGGGCCGGACCGAAGTGACAGGCGCCAACGTGCTCGTCGCCATCTTTGCGGAGCGGGAGAGCAATGCCGCCTATTTCC
TGCAAGAGCAGGACATGACGCGCTACGACGCCGTCAACTTTATCGCCCACGGGGTCGCCAAAGACCCCAGCTATGGCGAA
GCGCGTCCCGTGACCGGGGCCGAAGACGACGAGCAAGTCACGCCTAACGTTCAGGACGATGCGGGCGGGGAGGAGAAGGA
ATCCGCCCTTTCCAAATATTGCGTCGATCTGAATGCCAAGGCGACCAAGGGGGATGTAGATCCCCTGATCGGTCGCGCCT
CGGAAGTGGAGCGGTGCATTCAGGTCCTGTGCCGCCGCCGCAAGAACAACCCGCTTCTGGTGGGTGATCCCGGCGTGGGC
AAAACCGCAATCGCGGAAGGCTTGGCGAAGAAGATTGTTGAAGGCGAGACCCCCGAGGTGCTGGAAAATGCCACCATCTT
CTCCCTCGACATGGGCGCGTTGCTCGCCGGCACCCGCTATCGCGGTGACTTCGAGGAACGCCTGAAAGCTGTCGTCAAAG
AGCTGGAAGACCATCCTGACGCTGTTCTATTCATCGACGAGATCCACACCGTGATCGGTGCCGGTGCGACGTCTGGTGGG
GCAATGGATGCCTCCAACCTGCTGAAGCCTGCGTTGCAGGGCGGCGGTCTGCGCTGCATGGGCTCCACCACCTACAAGGA
ATTCCGCCAGCACTTCGAGAAGGACCGCGCCCTGTCGCGGCGCTTCCAGAAGATCGATGTGGAGGAGCCTTCGGTTGATG
ACGCGGTGAAAATCCTCAAGGGCCTGAAGCCGTATTTTGAGGAGCATCATTCGGTGAAATACACGGCCGATGCGATCAAG
ACGTCGGTCGAACTGGCCTCGCGCTACATCAATGACCGCAAATTGCCCGACAGCGCCATCGACGTGATCGACGAAGCCGG
TGCGGCGCAGCATCTGGTGGTGGAGAGCAAACGGCGCAAAACCATCGGCACCAAAGAAGTGGAAGACGTGGTGGCCAAGA
TCGCCCGCATTCCGCCCAAAACCGTGTCCAAGGATGATGCGATTGTTCTGAAAGACCTGGAGGTGTCACTGAAGCGTGTC
GTCTTCGGTCAGGACAAGGCGATTGAGGCTTTGGCCTCGTCCATCAAGCTGGCCCGTGCCGGCCTGAGGGAGCCTGAAAA
GCCCATCGGCAACTACCTGTTCGCCGGTCCCACCGGTGTGGGTAAGACCGAGGTTGCCAAGCAATTGGCAGACACCCTTG
GCGTGGAACTGATCCGGTTCGACATGTCCGAGTACATGGAAAAGCACGCGGTCTCGCGTTTGATCGGTGCCCCTCCGGGC
TATGTCGGCTTTGACCAGGGCGGTCTTCTGACCGATGGCATCGACCAGCATCCCCATTGCGTGTTGCTGCTGGATGAGAT
CGAGAAGGCGCACCCGGATGTCTTCAACATCCTGTTGCAGGTCATGGACCACGGCACTCTGACGGATCATAACGGACGCT
CCGTCGACTTCCGGAACGTGGTTTTGATCATGACCTCCAACGCAGGTGCGGCGGAGCAAGCGAAGGCAGCCATCGGCTTC
AACCGTGACCGTCGGGAGGGTGAGGATACGGCCGCGATCGAGCGGACCTTCACACCGGAATTCCGCAACCGGCTGGATGC
GGTGATCTCCTTCGGGCCGCTCCCGAAAGAGGTGATCCTGCAGGTGGTCGAGAAGTTCGTGCTTCAGCTGGAAGCGCAAC
TGATGGACCGCAACGTCACGATCGAGCTCACCAAGCCCGCAGCCGAATGGCTGGCTGACAAAGGATATGACGACCGCATG
GGCGCACGGCCACTGGGTCGCGTGATCCAGGAACATATCAAAAAGCCCCTCGCGGAGGAGCTGTTGTTCGGGAAACTGGC
CAAAGGTGGCAACGTCCAGGTCGGAGTGAAAGACGGCAAAATCGATCTGCGCGTGGAGGAGGCGGGAAGCCCGCGCCTCT
CTCCCAAGAAGAAGCCGCCGCTTCTGACCGCAGACTGA

Upstream 100 bases:

>100_bases
GGAAACACACAGTGGTGATGCGAATTTGCTTGAAACCCGGCGGTGGAAAGCAAAATTTAACATTATGAGGCCACCATCGA
GTGGACGCTAGCAGCCCTCG

Downstream 100 bases:

>100_bases
TCGCGTCTTGGTATCTTACTTATTGAGAGGGCTGGGGACGATTTCCCCGGCCCTTTCTTTTTGCAGATTACAGTGAACGG
CCAGAACTTTCCGGGCGAAC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MQTKGAQIVPSFSNTLEQAIHAALANANARRHELATLEHLLLALIDEPDAQKVMKACSVDIEVLRDTLSKFIDDDLSTLE
TDVEGSEAVPTAAFQRVIQRAAIHVQSSGRTEVTGANVLVAIFAERESNAAYFLQEQDMTRYDAVNFIAHGVAKDPSYGE
ARPVTGAEDDEQVTPNVQDDAGGEEKESALSKYCVDLNAKATKGDVDPLIGRASEVERCIQVLCRRRKNNPLLVGDPGVG
KTAIAEGLAKKIVEGETPEVLENATIFSLDMGALLAGTRYRGDFEERLKAVVKELEDHPDAVLFIDEIHTVIGAGATSGG
AMDASNLLKPALQGGGLRCMGSTTYKEFRQHFEKDRALSRRFQKIDVEEPSVDDAVKILKGLKPYFEEHHSVKYTADAIK
TSVELASRYINDRKLPDSAIDVIDEAGAAQHLVVESKRRKTIGTKEVEDVVAKIARIPPKTVSKDDAIVLKDLEVSLKRV
VFGQDKAIEALASSIKLARAGLREPEKPIGNYLFAGPTGVGKTEVAKQLADTLGVELIRFDMSEYMEKHAVSRLIGAPPG
YVGFDQGGLLTDGIDQHPHCVLLLDEIEKAHPDVFNILLQVMDHGTLTDHNGRSVDFRNVVLIMTSNAGAAEQAKAAIGF
NRDRREGEDTAAIERTFTPEFRNRLDAVISFGPLPKEVILQVVEKFVLQLEAQLMDRNVTIELTKPAAEWLADKGYDDRM
GARPLGRVIQEHIKKPLAEELLFGKLAKGGNVQVGVKDGKIDLRVEEAGSPRLSPKKKPPLLTAD

Sequences:

>Translated_785_residues
MQTKGAQIVPSFSNTLEQAIHAALANANARRHELATLEHLLLALIDEPDAQKVMKACSVDIEVLRDTLSKFIDDDLSTLE
TDVEGSEAVPTAAFQRVIQRAAIHVQSSGRTEVTGANVLVAIFAERESNAAYFLQEQDMTRYDAVNFIAHGVAKDPSYGE
ARPVTGAEDDEQVTPNVQDDAGGEEKESALSKYCVDLNAKATKGDVDPLIGRASEVERCIQVLCRRRKNNPLLVGDPGVG
KTAIAEGLAKKIVEGETPEVLENATIFSLDMGALLAGTRYRGDFEERLKAVVKELEDHPDAVLFIDEIHTVIGAGATSGG
AMDASNLLKPALQGGGLRCMGSTTYKEFRQHFEKDRALSRRFQKIDVEEPSVDDAVKILKGLKPYFEEHHSVKYTADAIK
TSVELASRYINDRKLPDSAIDVIDEAGAAQHLVVESKRRKTIGTKEVEDVVAKIARIPPKTVSKDDAIVLKDLEVSLKRV
VFGQDKAIEALASSIKLARAGLREPEKPIGNYLFAGPTGVGKTEVAKQLADTLGVELIRFDMSEYMEKHAVSRLIGAPPG
YVGFDQGGLLTDGIDQHPHCVLLLDEIEKAHPDVFNILLQVMDHGTLTDHNGRSVDFRNVVLIMTSNAGAAEQAKAAIGF
NRDRREGEDTAAIERTFTPEFRNRLDAVISFGPLPKEVILQVVEKFVLQLEAQLMDRNVTIELTKPAAEWLADKGYDDRM
GARPLGRVIQEHIKKPLAEELLFGKLAKGGNVQVGVKDGKIDLRVEEAGSPRLSPKKKPPLLTAD
>Mature_785_residues
MQTKGAQIVPSFSNTLEQAIHAALANANARRHELATLEHLLLALIDEPDAQKVMKACSVDIEVLRDTLSKFIDDDLSTLE
TDVEGSEAVPTAAFQRVIQRAAIHVQSSGRTEVTGANVLVAIFAERESNAAYFLQEQDMTRYDAVNFIAHGVAKDPSYGE
ARPVTGAEDDEQVTPNVQDDAGGEEKESALSKYCVDLNAKATKGDVDPLIGRASEVERCIQVLCRRRKNNPLLVGDPGVG
KTAIAEGLAKKIVEGETPEVLENATIFSLDMGALLAGTRYRGDFEERLKAVVKELEDHPDAVLFIDEIHTVIGAGATSGG
AMDASNLLKPALQGGGLRCMGSTTYKEFRQHFEKDRALSRRFQKIDVEEPSVDDAVKILKGLKPYFEEHHSVKYTADAIK
TSVELASRYINDRKLPDSAIDVIDEAGAAQHLVVESKRRKTIGTKEVEDVVAKIARIPPKTVSKDDAIVLKDLEVSLKRV
VFGQDKAIEALASSIKLARAGLREPEKPIGNYLFAGPTGVGKTEVAKQLADTLGVELIRFDMSEYMEKHAVSRLIGAPPG
YVGFDQGGLLTDGIDQHPHCVLLLDEIEKAHPDVFNILLQVMDHGTLTDHNGRSVDFRNVVLIMTSNAGAAEQAKAAIGF
NRDRREGEDTAAIERTFTPEFRNRLDAVISFGPLPKEVILQVVEKFVLQLEAQLMDRNVTIELTKPAAEWLADKGYDDRM
GARPLGRVIQEHIKKPLAEELLFGKLAKGGNVQVGVKDGKIDLRVEEAGSPRLSPKKKPPLLTAD

Specific function: ATP-Dependent Specificity Component Of The Clpp Protease. It Directs The Protease To Specific Substrates. The Primary Function Of The Clpa-Clpp Complex Appears To Be The Degradation Of Unfolded Or Abnormal Proteins. [C]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=343, Percent_Identity=32.6530612244898, Blast_Score=169, Evalue=1e-41,
Organism=Escherichia coli, GI1787109, Length=752, Percent_Identity=59.0425531914894, Blast_Score=911, Evalue=0.0,
Organism=Escherichia coli, GI1788943, Length=260, Percent_Identity=55, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6320464, Length=335, Percent_Identity=44.4776119402985, Blast_Score=277, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6323002, Length=356, Percent_Identity=40.4494382022472, Blast_Score=253, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR013461
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 85707; Mature: 85707

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKGAQIVPSFSNTLEQAIHAALANANARRHELATLEHLLLALIDEPDAQKVMKACSVD
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IEVLRDTLSKFIDDDLSTLETDVEGSEAVPTAAFQRVIQRAAIHVQSSGRTEVTGANVLV
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
AIFAERESNAAYFLQEQDMTRYDAVNFIAHGVAKDPSYGEARPVTGAEDDEQVTPNVQDD
EEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGEEKESALSKYCVDLNAKATKGDVDPLIGRASEVERCIQVLCRRRKNNPLLVGDPGVG
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCC
KTAIAEGLAKKIVEGETPEVLENATIFSLDMGALLAGTRYRGDFEERLKAVVKELEDHPD
HHHHHHHHHHHHHCCCCHHHHHCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
AVLFIDEIHTVIGAGATSGGAMDASNLLKPALQGGGLRCMGSTTYKEFRQHFEKDRALSR
EEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
RFQKIDVEEPSVDDAVKILKGLKPYFEEHHSVKYTADAIKTSVELASRYINDRKLPDSAI
HHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHH
DVIDEAGAAQHLVVESKRRKTIGTKEVEDVVAKIARIPPKTVSKDDAIVLKDLEVSLKRV
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHH
VFGQDKAIEALASSIKLARAGLREPEKPIGNYLFAGPTGVGKTEVAKQLADTLGVELIRF
HCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DMSEYMEKHAVSRLIGAPPGYVGFDQGGLLTDGIDQHPHCVLLLDEIEKAHPDVFNILLQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCHHHHHHHH
VMDHGTLTDHNGRSVDFRNVVLIMTSNAGAAEQAKAAIGFNRDRREGEDTAAIERTFTPE
HHCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCHH
FRNRLDAVISFGPLPKEVILQVVEKFVLQLEAQLMDRNVTIELTKPAAEWLADKGYDDRM
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCC
GARPLGRVIQEHIKKPLAEELLFGKLAKGGNVQVGVKDGKIDLRVEEAGSPRLSPKKKPP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCC
LLTAD
CCCCC
>Mature Secondary Structure
MQTKGAQIVPSFSNTLEQAIHAALANANARRHELATLEHLLLALIDEPDAQKVMKACSVD
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IEVLRDTLSKFIDDDLSTLETDVEGSEAVPTAAFQRVIQRAAIHVQSSGRTEVTGANVLV
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
AIFAERESNAAYFLQEQDMTRYDAVNFIAHGVAKDPSYGEARPVTGAEDDEQVTPNVQDD
EEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGEEKESALSKYCVDLNAKATKGDVDPLIGRASEVERCIQVLCRRRKNNPLLVGDPGVG
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCC
KTAIAEGLAKKIVEGETPEVLENATIFSLDMGALLAGTRYRGDFEERLKAVVKELEDHPD
HHHHHHHHHHHHHCCCCHHHHHCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
AVLFIDEIHTVIGAGATSGGAMDASNLLKPALQGGGLRCMGSTTYKEFRQHFEKDRALSR
EEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
RFQKIDVEEPSVDDAVKILKGLKPYFEEHHSVKYTADAIKTSVELASRYINDRKLPDSAI
HHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHH
DVIDEAGAAQHLVVESKRRKTIGTKEVEDVVAKIARIPPKTVSKDDAIVLKDLEVSLKRV
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHH
VFGQDKAIEALASSIKLARAGLREPEKPIGNYLFAGPTGVGKTEVAKQLADTLGVELIRF
HCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DMSEYMEKHAVSRLIGAPPGYVGFDQGGLLTDGIDQHPHCVLLLDEIEKAHPDVFNILLQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCHHHHHHHH
VMDHGTLTDHNGRSVDFRNVVLIMTSNAGAAEQAKAAIGFNRDRREGEDTAAIERTFTPE
HHCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCHH
FRNRLDAVISFGPLPKEVILQVVEKFVLQLEAQLMDRNVTIELTKPAAEWLADKGYDDRM
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCC
GARPLGRVIQEHIKKPLAEELLFGKLAKGGNVQVGVKDGKIDLRVEEAGSPRLSPKKKPP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCC
LLTAD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6209404 [H]