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The map label for this gene is argD

Identifier: 89053515

GI number: 89053515

Start: 976894

End: 978081

Strand: Reverse

Name: argD

Synonym: Jann_1024

Alternate gene names: 89053515

Gene position: 978081-976894 (Counterclockwise)

Preceding gene: 89053516

Following gene: 89053514

Centisome position: 22.65

GC content: 65.15

Gene sequence:

>1188_bases
ATGATCTCGCCTGTCCTACCCAGCTATTCCCGCGCAAACCTGTCCTTCGTCAAAGGCGAAGGGTCCTGGCTCGTGGACGC
GGATGGGCGACGTTTTCTGGATTTCGCCAGCGGCATCGCGGTGATGTCGCTCGGCCACGGGCACCCCAAGGTCGTGAGCG
CCCTGATGGAACAGGCCCACGCGCTGTGGCACACGTCCAATCTCTACGAGGTGCCGCAGCAAAAGGCCCTGGCCGAGCGG
TTGGTGGACCATACGTTCGCGGATACGGTGTTTTTCTGCAATTCCGGCACGGAAGCGGCCGAGCTTGCGATCAAGATGGC
TCGCAAATACCGCACGGAAACGGGCAGCCCCGACCGGATGACGATCCTGACGTTCGAGGGGTCTTTCCACGGCCGCTCCA
CCGGGGCGATTTCGGCGGCGGGCTCAGAAAAACTGTCCGCCGGGTTCGGCCCCCTGCTCGGCGGCTTCAAAACGCTACCC
TTCGGCGATCACGACGCCCTGCGCGCCGCCGCAAGCGCCCCTGATGTGGGCGCCATCATGGTGGAGCCGATCCAGGGTGA
AGGTGGCATTCGCCCGGTCCCCGACCAGTGCCTCAAGGGCCTGCGCGATCTGTGCGATGAACATGGCCTGCTGCTGATCT
TCGATGAGATCCAATGCGGCGTGGGCCGGACGGGCAAGCTCTTTGCCCATGAATGGGCGGGCATCGCGCCCGATATCATG
CTGGTGGCCAAGGGCATCGGCTCGGGCTTTCCCATCGGCGCGCTTCTGGCCACCGAGGAGGCCGCGCAGGGCATGACAGC
GGGCACCCACGGCTCCACCTATGGCGGCAACCCGCTTGGCTGCGCGGTGGGCACGGCGGTGATGGATGTCATCACCGAGG
ATGGATTTCTGGACGACGTGAACGCCAAGGCGGGCTTCCTGCGCCAGAAGCTGGAGGGCCTCGTGGCGTCTCATCCGACG
ATTTTTGAGGGCGTCCGCGGCGCAGGCCTCCTCCTCGGCCTCAAATGCAGGATCGCCCCCGGCGATGTCGTGGCGGAGGG
CTACAAACACGATGTGCTCACCGTGCCCGCCGCGGACAATGTTGTCCGGGTGTTGCCCGCGCTAACGATCTCGGAGGATG
AAATCTCCACAGGTATCTCCCGCCTCGATGCGACAGCCACGGCGCTGGAGGCAAGGGCCGCCGCCTAA

Upstream 100 bases:

>100_bases
GATCACCACCGGCACTTGACCCCATCAGCATCGGTGAATTGACTAGGCCGCGCGCCCGGTGCAACAGGGTGTCTTCTTCA
ATCTCAACGGAGTCCGGTCG

Downstream 100 bases:

>100_bases
CCCTTTCCCCGTTCCTGAAATATCCCGGGGGGTGCGGGGGGCTGGTCCCCCGCCTCCGCCGCCAGCCACAGGCGCAAACC
CATGCCAAATTTCCTCGACA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MISPVLPSYSRANLSFVKGEGSWLVDADGRRFLDFASGIAVMSLGHGHPKVVSALMEQAHALWHTSNLYEVPQQKALAER
LVDHTFADTVFFCNSGTEAAELAIKMARKYRTETGSPDRMTILTFEGSFHGRSTGAISAAGSEKLSAGFGPLLGGFKTLP
FGDHDALRAAASAPDVGAIMVEPIQGEGGIRPVPDQCLKGLRDLCDEHGLLLIFDEIQCGVGRTGKLFAHEWAGIAPDIM
LVAKGIGSGFPIGALLATEEAAQGMTAGTHGSTYGGNPLGCAVGTAVMDVITEDGFLDDVNAKAGFLRQKLEGLVASHPT
IFEGVRGAGLLLGLKCRIAPGDVVAEGYKHDVLTVPAADNVVRVLPALTISEDEISTGISRLDATATALEARAAA

Sequences:

>Translated_395_residues
MISPVLPSYSRANLSFVKGEGSWLVDADGRRFLDFASGIAVMSLGHGHPKVVSALMEQAHALWHTSNLYEVPQQKALAER
LVDHTFADTVFFCNSGTEAAELAIKMARKYRTETGSPDRMTILTFEGSFHGRSTGAISAAGSEKLSAGFGPLLGGFKTLP
FGDHDALRAAASAPDVGAIMVEPIQGEGGIRPVPDQCLKGLRDLCDEHGLLLIFDEIQCGVGRTGKLFAHEWAGIAPDIM
LVAKGIGSGFPIGALLATEEAAQGMTAGTHGSTYGGNPLGCAVGTAVMDVITEDGFLDDVNAKAGFLRQKLEGLVASHPT
IFEGVRGAGLLLGLKCRIAPGDVVAEGYKHDVLTVPAADNVVRVLPALTISEDEISTGISRLDATATALEARAAA
>Mature_395_residues
MISPVLPSYSRANLSFVKGEGSWLVDADGRRFLDFASGIAVMSLGHGHPKVVSALMEQAHALWHTSNLYEVPQQKALAER
LVDHTFADTVFFCNSGTEAAELAIKMARKYRTETGSPDRMTILTFEGSFHGRSTGAISAAGSEKLSAGFGPLLGGFKTLP
FGDHDALRAAASAPDVGAIMVEPIQGEGGIRPVPDQCLKGLRDLCDEHGLLLIFDEIQCGVGRTGKLFAHEWAGIAPDIM
LVAKGIGSGFPIGALLATEEAAQGMTAGTHGSTYGGNPLGCAVGTAVMDVITEDGFLDDVNAKAGFLRQKLEGLVASHPT
IFEGVRGAGLLLGLKCRIAPGDVVAEGYKHDVLTVPAADNVVRVLPALTISEDEISTGISRLDATATALEARAAA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=386, Percent_Identity=34.7150259067358, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI13994255, Length=450, Percent_Identity=31.3333333333333, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.6666666666667, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=26.5882352941176, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI24119277, Length=422, Percent_Identity=27.7251184834123, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=26.1176470588235, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=27.3417721518987, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI188536080, Length=371, Percent_Identity=25.0673854447439, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679950, Length=371, Percent_Identity=25.0673854447439, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679946, Length=371, Percent_Identity=25.0673854447439, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788044, Length=395, Percent_Identity=43.2911392405063, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=42.1465968586387, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI145693181, Length=371, Percent_Identity=36.6576819407008, Blast_Score=227, Evalue=8e-61,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=32.9177057356608, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=32.4937027707809, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1786991, Length=337, Percent_Identity=34.7181008902077, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786349, Length=303, Percent_Identity=32.013201320132, Blast_Score=124, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=33.419689119171, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=31.0502283105023, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=34.9090909090909, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=434, Percent_Identity=28.110599078341, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=376, Percent_Identity=26.3297872340426, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=33.1288343558282, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=38.9447236180905, Blast_Score=285, Evalue=6e-78,
Organism=Saccharomyces cerevisiae, GI6323470, Length=398, Percent_Identity=32.9145728643216, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6321456, Length=441, Percent_Identity=25.1700680272109, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=344, Percent_Identity=25.5813953488372, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357415, Length=387, Percent_Identity=32.5581395348837, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28574759, Length=375, Percent_Identity=34.4, Blast_Score=178, Evalue=7e-45,
Organism=Drosophila melanogaster, GI161085790, Length=375, Percent_Identity=34.4, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI21356575, Length=360, Percent_Identity=31.1111111111111, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281366494, Length=423, Percent_Identity=24.113475177305, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24667139, Length=423, Percent_Identity=24.113475177305, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24667143, Length=423, Percent_Identity=24.113475177305, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41292; Mature: 41292

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPVLPSYSRANLSFVKGEGSWLVDADGRRFLDFASGIAVMSLGHGHPKVVSALMEQAH
CCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHCCHHEEECCCCCHHHHHHHHHHHH
ALWHTSNLYEVPQQKALAERLVDHTFADTVFFCNSGTEAAELAIKMARKYRTETGSPDRM
HHHHCCCHHHCHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEE
TILTFEGSFHGRSTGAISAAGSEKLSAGFGPLLGGFKTLPFGDHDALRAAASAPDVGAIM
EEEEEECCCCCCCCCCEECCCCHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEE
VEPIQGEGGIRPVPDQCLKGLRDLCDEHGLLLIFDEIQCGVGRTGKLFAHEWAGIAPDIM
EEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHCCCCHHHH
LVAKGIGSGFPIGALLATEEAAQGMTAGTHGSTYGGNPLGCAVGTAVMDVITEDGFLDDV
HHHHHCCCCCCHHHHEECHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NAKAGFLRQKLEGLVASHPTIFEGVRGAGLLLGLKCRIAPGDVVAEGYKHDVLTVPAADN
CHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEECCCHHHHCCCCCCEEEECCCCC
VVRVLPALTISEDEISTGISRLDATATALEARAAA
HHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISPVLPSYSRANLSFVKGEGSWLVDADGRRFLDFASGIAVMSLGHGHPKVVSALMEQAH
CCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHCCHHEEECCCCCHHHHHHHHHHHH
ALWHTSNLYEVPQQKALAERLVDHTFADTVFFCNSGTEAAELAIKMARKYRTETGSPDRM
HHHHCCCHHHCHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEE
TILTFEGSFHGRSTGAISAAGSEKLSAGFGPLLGGFKTLPFGDHDALRAAASAPDVGAIM
EEEEEECCCCCCCCCCEECCCCHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEE
VEPIQGEGGIRPVPDQCLKGLRDLCDEHGLLLIFDEIQCGVGRTGKLFAHEWAGIAPDIM
EEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHCCCCHHHH
LVAKGIGSGFPIGALLATEEAAQGMTAGTHGSTYGGNPLGCAVGTAVMDVITEDGFLDDV
HHHHHCCCCCCHHHHEECHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NAKAGFLRQKLEGLVASHPTIFEGVRGAGLLLGLKCRIAPGDVVAEGYKHDVLTVPAADN
CHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEECCCHHHHCCCCCCEEEECCCCC
VVRVLPALTISEDEISTGISRLDATATALEARAAA
HHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]