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The map label for this gene is argF [H]

Identifier: 89053514

GI number: 89053514

Start: 975886

End: 976812

Strand: Reverse

Name: argF [H]

Synonym: Jann_1023

Alternate gene names: 89053514

Gene position: 976812-975886 (Counterclockwise)

Preceding gene: 89053515

Following gene: 89053513

Centisome position: 22.62

GC content: 62.68

Gene sequence:

>927_bases
ATGCCAAATTTCCTCGACATCCACACCACAGACCCTGCCGCCCTGCGCGATATCCTTGCGCAAGCGGGCAATATGAAAAC
CGCGCGCGGCACGCGGCCCAAAGGCACGCCCGACGACGATCAACCCCTCGCGGGCCATGTCGTCGCGCTGATCTTCGAGA
AACCCTCCACCCGCACCCGCGTGTCCTTTGACGTTGGCGTGCGCCAGATGGGCGGCAGCACGCTTGTCCTTTCGGGCGCA
GAGATGCAACTGGGCCACGGAGAGACTATCGCTGACACCGCCCGCGTCCTCTCGCGCTATGTGGACCTCATCATGATCCG
CACCTTCGGCGAGGATATCCTCCATGAGATGGCCGAACATGCCACCGTTCCGGTGATAAACGGCCTCACCGACAATTCGC
ACCCTTGCCAGATCATGGCCGATGTTATGACGTTTGAAGAACATCGCGGCCCGATCAAAGGCAAACGCGTGGCCTGGATG
GGCGATGGCAACAACGTGGCGCAAAGTTTTCTCCATGCCGCCGCCAGCTTTGGGTTTGATTTCACCTTCTCCGGCCCCGC
GCAGCTTGATCCCCGCGATGATCTTGTCGGCGCGGTGCGCAAGGCCGGTCAGGACGTGCGCATTGAACGGGACCCGGCGA
AAGCCGTCGCCGACGCCGATCTGGTCGTCACCGATACCTGGGTCTCGATGGGTGATGCGGAATCCTCGCGCCAGCGCCGC
CACAACCTCCTGCGCCCCTATCAGGTGAACGAACGCCTCATGGACGCGGCACCAGATCACGCCATGGTCATGCATTGCCT
GCCCGCCCATCGCGGCGAAGAGGTCACCGATGCCATCCTCGACGGTCCCCGCTCCGTCGTGTTTGACGAGGCCGAGAACC
GCCTCCATGCCCAAAAGGCCATCATGCGCTGGTGCCTTGATGCCTGA

Upstream 100 bases:

>100_bases
GGCAAGGGCCGCCGCCTAACCCTTTCCCCGTTCCTGAAATATCCCGGGGGGTGCGGGGGGCTGGTCCCCCGCCTCCGCCG
CCAGCCACAGGCGCAAACCC

Downstream 100 bases:

>100_bases
CGCGCGATCATGACCGCCGTGGCGACAGAGCATGGCCTGGCCCGGCCCTCCCCGGGGTTGGCCGTTGCCTTCATGCTCTG
CGCCACGGCGTTTATTGCGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPNFLDIHTTDPAALRDILAQAGNMKTARGTRPKGTPDDDQPLAGHVVALIFEKPSTRTRVSFDVGVRQMGGSTLVLSGA
EMQLGHGETIADTARVLSRYVDLIMIRTFGEDILHEMAEHATVPVINGLTDNSHPCQIMADVMTFEEHRGPIKGKRVAWM
GDGNNVAQSFLHAAASFGFDFTFSGPAQLDPRDDLVGAVRKAGQDVRIERDPAKAVADADLVVTDTWVSMGDAESSRQRR
HNLLRPYQVNERLMDAAPDHAMVMHCLPAHRGEEVTDAILDGPRSVVFDEAENRLHAQKAIMRWCLDA

Sequences:

>Translated_308_residues
MPNFLDIHTTDPAALRDILAQAGNMKTARGTRPKGTPDDDQPLAGHVVALIFEKPSTRTRVSFDVGVRQMGGSTLVLSGA
EMQLGHGETIADTARVLSRYVDLIMIRTFGEDILHEMAEHATVPVINGLTDNSHPCQIMADVMTFEEHRGPIKGKRVAWM
GDGNNVAQSFLHAAASFGFDFTFSGPAQLDPRDDLVGAVRKAGQDVRIERDPAKAVADADLVVTDTWVSMGDAESSRQRR
HNLLRPYQVNERLMDAAPDHAMVMHCLPAHRGEEVTDAILDGPRSVVFDEAENRLHAQKAIMRWCLDA
>Mature_307_residues
PNFLDIHTTDPAALRDILAQAGNMKTARGTRPKGTPDDDQPLAGHVVALIFEKPSTRTRVSFDVGVRQMGGSTLVLSGAE
MQLGHGETIADTARVLSRYVDLIMIRTFGEDILHEMAEHATVPVINGLTDNSHPCQIMADVMTFEEHRGPIKGKRVAWMG
DGNNVAQSFLHAAASFGFDFTFSGPAQLDPRDDLVGAVRKAGQDVRIERDPAKAVADADLVVTDTWVSMGDAESSRQRRH
NLLRPYQVNERLMDAAPDHAMVMHCLPAHRGEEVTDAILDGPRSVVFDEAENRLHAQKAIMRWCLDA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=264, Percent_Identity=37.1212121212121, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI18105007, Length=265, Percent_Identity=25.2830188679245, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1790703, Length=329, Percent_Identity=38.6018237082067, Blast_Score=213, Evalue=9e-57,
Organism=Escherichia coli, GI1786469, Length=330, Percent_Identity=38.7878787878788, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI2367364, Length=297, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=124, Percent_Identity=33.0645161290323, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=298, Percent_Identity=33.8926174496644, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322331, Length=265, Percent_Identity=27.1698113207547, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24642586, Length=296, Percent_Identity=26.0135135135135, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 33794; Mature: 33662

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFLDIHTTDPAALRDILAQAGNMKTARGTRPKGTPDDDQPLAGHVVALIFEKPSTRTR
CCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEE
VSFDVGVRQMGGSTLVLSGAEMQLGHGETIADTARVLSRYVDLIMIRTFGEDILHEMAEH
EEEEHHHHHCCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATVPVINGLTDNSHPCQIMADVMTFEEHRGPIKGKRVAWMGDGNNVAQSFLHAAASFGFD
CCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCC
FTFSGPAQLDPRDDLVGAVRKAGQDVRIERDPAKAVADADLVVTDTWVSMGDAESSRQRR
EEECCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHHCCCCEEEEECHHHCCCCHHHHHHH
HNLLRPYQVNERLMDAAPDHAMVMHCLPAHRGEEVTDAILDGPRSVVFDEAENRLHAQKA
HHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHH
IMRWCLDA
HHHHHHCC
>Mature Secondary Structure 
PNFLDIHTTDPAALRDILAQAGNMKTARGTRPKGTPDDDQPLAGHVVALIFEKPSTRTR
CCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEE
VSFDVGVRQMGGSTLVLSGAEMQLGHGETIADTARVLSRYVDLIMIRTFGEDILHEMAEH
EEEEHHHHHCCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATVPVINGLTDNSHPCQIMADVMTFEEHRGPIKGKRVAWMGDGNNVAQSFLHAAASFGFD
CCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCC
FTFSGPAQLDPRDDLVGAVRKAGQDVRIERDPAKAVADADLVVTDTWVSMGDAESSRQRR
EEECCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHHCCCCEEEEECHHHCCCCHHHHHHH
HNLLRPYQVNERLMDAAPDHAMVMHCLPAHRGEEVTDAILDGPRSVVFDEAENRLHAQKA
HHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHH
IMRWCLDA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA