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The map label for this gene is lpsI [H]

Identifier: 89053500

GI number: 89053500

Start: 964285

End: 964980

Strand: Reverse

Name: lpsI [H]

Synonym: Jann_1009

Alternate gene names: 89053500

Gene position: 964980-964285 (Counterclockwise)

Preceding gene: 89053501

Following gene: 89053499

Centisome position: 22.35

GC content: 61.78

Gene sequence:

>696_bases
ATGAAAAAGGTCTTTGGCTCGGCAGCGGACGCCCTTGATGGGGTCCTGTTTGACGGAATGATGATCGCGGCGGGCGGCTT
CGGCCTTTGCGGTATCCCGGAATTGCTGATCGACGGTATCGTCGCGGCGGGCACCAAGGACATCACCATTGCGTCCAACA
ATGCGGGCGTGGATGATTTCGGCCTCGGCAAGCTGTTGGCGACCCGACAGGTCAAGAAGATGATGTCCAGCTACGTGGGC
GAGAACGCGGAATTCATGCGGCAATATCTGTCGGGCGAGCTGGAGTTGGAGTTCAACCCCCAGGGCACTCTGGCCGAGCG
GATGCGCGCAGGCGGTGCGGGCATCCCCGGCTTTTACACCAAGACCGGCGTGGGCACGGTGATCGCCGAGGGGAAAGAGG
TGAAACGCTGGGGTGAGCAGGACTATATACTGGAAGAAGGCATTTTCGCCGACCTCTCCATCGTGAAGGCCTGGAAGGCC
GACGCCACGGGCAACGCCGTGTTCCGCAAAACCGCGCGCAACTTCAACCCGCCCGCCGCCATGTGCGGCAAAGTCTGCAT
CCTTGAGGTTGAGGAGATCGTGGAGACCGGCAGCCTCGACGGCGACGCCATCCACCTGCCCGGCATCTATGTGCACCGCA
TGATCCAGGGCGAACATGAAAAACGGATCGAGCAGCGCACCACCCGCGCCGCTTGA

Upstream 100 bases:

>100_bases
GTAGCCTCGGCACACCGGGACACCCCCAGCGCCGCGTTGACTTCACCGCCCCCCTCCGCCAATTTGCCGCCAACATCAGA
CAGCACGGGGATTGCGCGCG

Downstream 100 bases:

>100_bases
GCCATGGTCGACCGGGTCTTCCCAACGGCACGGATCGAGGGCGTCTCGCCCAACATTCCGGTCCGCGATGTAGAAGCCAG
CCTGCGATTTTACCGCGATG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKKVFGSAADALDGVLFDGMMIAAGGFGLCGIPELLIDGIVAAGTKDITIASNNAGVDDFGLGKLLATRQVKKMMSSYVG
ENAEFMRQYLSGELELEFNPQGTLAERMRAGGAGIPGFYTKTGVGTVIAEGKEVKRWGEQDYILEEGIFADLSIVKAWKA
DATGNAVFRKTARNFNPPAAMCGKVCILEVEEIVETGSLDGDAIHLPGIYVHRMIQGEHEKRIEQRTTRAA

Sequences:

>Translated_231_residues
MKKVFGSAADALDGVLFDGMMIAAGGFGLCGIPELLIDGIVAAGTKDITIASNNAGVDDFGLGKLLATRQVKKMMSSYVG
ENAEFMRQYLSGELELEFNPQGTLAERMRAGGAGIPGFYTKTGVGTVIAEGKEVKRWGEQDYILEEGIFADLSIVKAWKA
DATGNAVFRKTARNFNPPAAMCGKVCILEVEEIVETGSLDGDAIHLPGIYVHRMIQGEHEKRIEQRTTRAA
>Mature_231_residues
MKKVFGSAADALDGVLFDGMMIAAGGFGLCGIPELLIDGIVAAGTKDITIASNNAGVDDFGLGKLLATRQVKKMMSSYVG
ENAEFMRQYLSGELELEFNPQGTLAERMRAGGAGIPGFYTKTGVGTVIAEGKEVKRWGEQDYILEEGIFADLSIVKAWKA
DATGNAVFRKTARNFNPPAAMCGKVCILEVEEIVETGSLDGDAIHLPGIYVHRMIQGEHEKRIEQRTTRAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=231, Percent_Identity=55.8441558441558, Blast_Score=264, Evalue=5e-71,
Organism=Homo sapiens, GI11545841, Length=229, Percent_Identity=51.528384279476, Blast_Score=218, Evalue=4e-57,
Organism=Escherichia coli, GI1788551, Length=221, Percent_Identity=38.4615384615385, Blast_Score=170, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=51.6393442622951, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=50.8264462809917, Blast_Score=239, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=50.8264462809917, Blast_Score=238, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24794; Mature: 24794

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVFGSAADALDGVLFDGMMIAAGGFGLCGIPELLIDGIVAAGTKDITIASNNAGVDDF
CCCCHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCC
GLGKLLATRQVKKMMSSYVGENAEFMRQYLSGELELEFNPQGTLAERMRAGGAGIPGFYT
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCH
KTGVGTVIAEGKEVKRWGEQDYILEEGIFADLSIVKAWKADATGNAVFRKTARNFNPPAA
HCCCHHHHHCCHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHH
MCGKVCILEVEEIVETGSLDGDAIHLPGIYVHRMIQGEHEKRIEQRTTRAA
HHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKVFGSAADALDGVLFDGMMIAAGGFGLCGIPELLIDGIVAAGTKDITIASNNAGVDDF
CCCCHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCC
GLGKLLATRQVKKMMSSYVGENAEFMRQYLSGELELEFNPQGTLAERMRAGGAGIPGFYT
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCH
KTGVGTVIAEGKEVKRWGEQDYILEEGIFADLSIVKAWKADATGNAVFRKTARNFNPPAA
HCCCHHHHHCCHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHH
MCGKVCILEVEEIVETGSLDGDAIHLPGIYVHRMIQGEHEKRIEQRTTRAA
HHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]