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The map label for this gene is hdaH [H]

Identifier: 89053501

GI number: 89053501

Start: 965077

End: 966177

Strand: Reverse

Name: hdaH [H]

Synonym: Jann_1010

Alternate gene names: 89053501

Gene position: 966177-965077 (Counterclockwise)

Preceding gene: 89053502

Following gene: 89053500

Centisome position: 22.38

GC content: 62.76

Gene sequence:

>1101_bases
ATGACCACCGGCTTTTTCTGGGATGAGCGGTGTTTCTGGCATTCGGGCGGGAATTATGCAGGTCTGTTGCAGGTCGGCGG
CCTGATCCAACCGGGCGGCGGGTTGCCCGAAAACCCCGAGACCAAGCGTCGCCTCGTCAATCTGTTGCGCGTCACCGGGT
TGTGGGAGGGGCTTGCGACCCAACAGGCCACCCCCGTGACGCAAGACGACCTCCTGCGCATTCATCCGTCCGACTATCTC
GCCAGCTTCAGGGCCAAATCGGCGGAGGGCGGCGGAGAGTTAGGCCTGCGCACACCGTTCGGCCCCGACGGGTATGACAT
CGCCTGCGTGTCCGCCGGGCTGGCGAAGGCTGCGCTGTTTGCCACGCTCAAAGGCGACGTGAAAAACGCCTATGCCCTGT
CGCGGCCCCCCGGCCACCATTGCCTGCCGGATTTTCCCAATGGCTTCTGCCTGCTCGCCAATATCGCCATCGCGATCGAG
GCTGCCCAGACCGTCAAGCTGACCGACCGTGTCGCGGTGATTGACTGGGACGTCCATCATGGCAACGGAACCGAGGCGAT
ATTCTACGACCGTGACGATGTCCTGACGATTTCATTGCATCAGGAGCGCAACTACCCGCTCGACACCGGCGATTTTGAAG
ATCGCGGATCCGAGGCGGGTGTGGGCTACAACCTCAACATTCCACTGCCCCCCGGCACCGGCCACGCAGGGTATGAGGAG
GCGTTCGAGCGGCTGGTGATCCCGTCCCTTCACGCCTTCCAACCCGATGCGATCATTGTGGCCTGCGGCTATGACGCATC
CCTCGTCGATCCGCTGAGCCGAATGATCGCAGGCGGCGACACTTTTCGCGCGATGACAGACATGACGATGGAAGCCGCGG
ATGATCTGTGCGGGGGCCGCCTGACCGTGGTGCACGAAGGCGGCTACTCCGAGGTTCACGTCCCCTTCCTTGGCCACGGC
GTGCTGGAATCGATGTCCGGCAGCGACATCCATGCGCCCGATCCGTTCCAGTACAAATTCGAAGGCCAGCAACCGGGCGC
ACGCTTCAATCGCTACGTCTCGACCCTGATCGCCGAGATGGAAGATGCTCTGGGGCTGTAG

Upstream 100 bases:

>100_bases
CAGGTCCGCGATCTTGCCGCCGCGCTGGATCTGCCGGAAGGCGCCTATCAGTTGCAACCCGAGGGATGAGCGCCCGGACC
CACACGGCAGGGGAGCGGTC

Downstream 100 bases:

>100_bases
CCTCGGCACACCGGGACACCCCCAGCGCCGCGTTGACTTCACCGCCCCCCTCCGCCAATTTGCCGCCAACATCAGACAGC
ACGGGGATTGCGCGCGATGA

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: HDAC-like amidohydrolase; HDAH [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTTGFFWDERCFWHSGGNYAGLLQVGGLIQPGGGLPENPETKRRLVNLLRVTGLWEGLATQQATPVTQDDLLRIHPSDYL
ASFRAKSAEGGGELGLRTPFGPDGYDIACVSAGLAKAALFATLKGDVKNAYALSRPPGHHCLPDFPNGFCLLANIAIAIE
AAQTVKLTDRVAVIDWDVHHGNGTEAIFYDRDDVLTISLHQERNYPLDTGDFEDRGSEAGVGYNLNIPLPPGTGHAGYEE
AFERLVIPSLHAFQPDAIIVACGYDASLVDPLSRMIAGGDTFRAMTDMTMEAADDLCGGRLTVVHEGGYSEVHVPFLGHG
VLESMSGSDIHAPDPFQYKFEGQQPGARFNRYVSTLIAEMEDALGL

Sequences:

>Translated_366_residues
MTTGFFWDERCFWHSGGNYAGLLQVGGLIQPGGGLPENPETKRRLVNLLRVTGLWEGLATQQATPVTQDDLLRIHPSDYL
ASFRAKSAEGGGELGLRTPFGPDGYDIACVSAGLAKAALFATLKGDVKNAYALSRPPGHHCLPDFPNGFCLLANIAIAIE
AAQTVKLTDRVAVIDWDVHHGNGTEAIFYDRDDVLTISLHQERNYPLDTGDFEDRGSEAGVGYNLNIPLPPGTGHAGYEE
AFERLVIPSLHAFQPDAIIVACGYDASLVDPLSRMIAGGDTFRAMTDMTMEAADDLCGGRLTVVHEGGYSEVHVPFLGHG
VLESMSGSDIHAPDPFQYKFEGQQPGARFNRYVSTLIAEMEDALGL
>Mature_365_residues
TTGFFWDERCFWHSGGNYAGLLQVGGLIQPGGGLPENPETKRRLVNLLRVTGLWEGLATQQATPVTQDDLLRIHPSDYLA
SFRAKSAEGGGELGLRTPFGPDGYDIACVSAGLAKAALFATLKGDVKNAYALSRPPGHHCLPDFPNGFCLLANIAIAIEA
AQTVKLTDRVAVIDWDVHHGNGTEAIFYDRDDVLTISLHQERNYPLDTGDFEDRGSEAGVGYNLNIPLPPGTGHAGYEEA
FERLVIPSLHAFQPDAIIVACGYDASLVDPLSRMIAGGDTFRAMTDMTMEAADDLCGGRLTVVHEGGYSEVHVPFLGHGV
LESMSGSDIHAPDPFQYKFEGQQPGARFNRYVSTLIAEMEDALGL

Specific function: Exhibits significant levels of protein deacetylase activity comparable to those of eukaryotic HDACs in assays both with fluorogenic peptidic substrates and acetate-radiolabeled histones. Accepts proteins with epsilon-acetylated lysine residues and tritiat

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=287, Percent_Identity=33.4494773519164, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI20070354, Length=284, Percent_Identity=33.4507042253521, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI153085395, Length=282, Percent_Identity=31.5602836879433, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI169234807, Length=255, Percent_Identity=30.5882352941176, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI148539870, Length=255, Percent_Identity=30.5882352941176, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI226529806, Length=284, Percent_Identity=31.6901408450704, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI62750349, Length=199, Percent_Identity=36.6834170854271, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI62750347, Length=199, Percent_Identity=36.6834170854271, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI17158039, Length=211, Percent_Identity=34.5971563981043, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI30795204, Length=211, Percent_Identity=34.5971563981043, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI30795202, Length=211, Percent_Identity=34.5971563981043, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI13128860, Length=268, Percent_Identity=29.1044776119403, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI293336691, Length=274, Percent_Identity=28.4671532846715, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI13128862, Length=257, Percent_Identity=28.0155642023346, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI8923769, Length=247, Percent_Identity=25.5060728744939, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI262073088, Length=161, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI209862883, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI262073092, Length=224, Percent_Identity=25.4464285714286, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=310, Percent_Identity=30, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17540332, Length=310, Percent_Identity=30, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=310, Percent_Identity=30, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17508561, Length=253, Percent_Identity=30.4347826086957, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17537347, Length=278, Percent_Identity=30.5755395683453, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193209491, Length=191, Percent_Identity=32.9842931937173, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17561978, Length=245, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25154020, Length=315, Percent_Identity=23.1746031746032, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=315, Percent_Identity=22.8571428571429, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17534739, Length=148, Percent_Identity=31.0810810810811, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=337, Percent_Identity=31.7507418397626, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323999, Length=248, Percent_Identity=30.241935483871, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321244, Length=233, Percent_Identity=29.1845493562232, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325325, Length=175, Percent_Identity=26.8571428571429, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325141, Length=62, Percent_Identity=48.3870967741936, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=311, Percent_Identity=30.8681672025724, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24642144, Length=312, Percent_Identity=30.7692307692308, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24642146, Length=312, Percent_Identity=30.7692307692308, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24642142, Length=312, Percent_Identity=30.7692307692308, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24641720, Length=211, Percent_Identity=36.9668246445498, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281360799, Length=211, Percent_Identity=36.9668246445498, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281360801, Length=211, Percent_Identity=36.9668246445498, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24657891, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644244, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 39492; Mature: 39361

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGFFWDERCFWHSGGNYAGLLQVGGLIQPGGGLPENPETKRRLVNLLRVTGLWEGLAT
CCCCEEECCEEEEECCCCEEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QQATPVTQDDLLRIHPSDYLASFRAKSAEGGGELGLRTPFGPDGYDIACVSAGLAKAALF
CCCCCCCHHCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
ATLKGDVKNAYALSRPPGHHCLPDFPNGFCLLANIAIAIEAAQTVKLTDRVAVIDWDVHH
HHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEECEEEEEEEEEEC
GNGTEAIFYDRDDVLTISLHQERNYPLDTGDFEDRGSEAGVGYNLNIPLPPGTGHAGYEE
CCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHH
AFERLVIPSLHAFQPDAIIVACGYDASLVDPLSRMIAGGDTFRAMTDMTMEAADDLCGGR
HHHHHHCCCHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCE
LTVVHEGGYSEVHVPFLGHGVLESMSGSDIHAPDPFQYKFEGQQPGARFNRYVSTLIAEM
EEEEECCCCCEEECCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
EDALGL
HHHHCC
>Mature Secondary Structure 
TTGFFWDERCFWHSGGNYAGLLQVGGLIQPGGGLPENPETKRRLVNLLRVTGLWEGLAT
CCCEEECCEEEEECCCCEEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QQATPVTQDDLLRIHPSDYLASFRAKSAEGGGELGLRTPFGPDGYDIACVSAGLAKAALF
CCCCCCCHHCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
ATLKGDVKNAYALSRPPGHHCLPDFPNGFCLLANIAIAIEAAQTVKLTDRVAVIDWDVHH
HHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEECEEEEEEEEEEC
GNGTEAIFYDRDDVLTISLHQERNYPLDTGDFEDRGSEAGVGYNLNIPLPPGTGHAGYEE
CCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHH
AFERLVIPSLHAFQPDAIIVACGYDASLVDPLSRMIAGGDTFRAMTDMTMEAADDLCGGR
HHHHHHCCCHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCE
LTVVHEGGYSEVHVPFLGHGVLESMSGSDIHAPDPFQYKFEGQQPGARFNRYVSTLIAEM
EEEEECCCCCEEECCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
EDALGL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA