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The map label for this gene is trpS [H]

Identifier: 89053385

GI number: 89053385

Start: 848001

End: 849026

Strand: Reverse

Name: trpS [H]

Synonym: Jann_0894

Alternate gene names: 89053385

Gene position: 849026-848001 (Counterclockwise)

Preceding gene: 89053387

Following gene: 89053383

Centisome position: 19.66

GC content: 61.4

Gene sequence:

>1026_bases
ATGGCCGAGACCCAGTTCACCCCCCGCGTCTTTTCGGGCATCCAGCCATCCGGCGGGCTGACCCTCGGCAATTATCTGGG
CGCGATCAAACGGTTTGTGGAAATGCAGGACGCCGGCACCCATGAAACCGTTTATTGCATGGTGGACCTGCACGCGATCA
CCGCGCGGCTTCTGTCGCCCGATGAGTTGCGCAACAACACCCGTGAACTTTGCGCAGGCTTCATCGCGTCGGGCATCGAC
CCCGAAAAGTCCATCCTGATCAACCAGTCCCAGGTCCCTGAACATGCGCAACTGGCCTGGATCTTCAACTGCATCGCCCG
GATGGGGTGGATGGGCCGCATGACCCAGTGGAAGGACAAATCCGGCAAGGACGCGGAAGGCGCGTCCCTCGGCCTCTTCG
CGTACCCTGCGCTGATGGCCGCCGATATCCTCGTCTACCACGCCACCCATGTGCCCGTGGGGGATGACCAGAAACAGCAC
CTGGAACTGACCCGTGATATCGCCGCTAAGTTCAACCATGATTACGGCGTGGAGTTCTTCCCGATCACCGAGCCCGTGAT
TGAAGGGGCCGCGACGCGCGTAATGAACCTGCAGGACGGCACCAAGAAGATGTCGAAATCCGATCCGGTGGAAAAGACCC
GCATCAACATGACCGATGACGCCGATGCCATTGCGCGCAAGATCCGCAAGGCCAAGACGGACCCCGATCCCCTGCCCGAT
GCGGTGGATGGGCTGGCGGCGCGGCCTGATGCCCGCAATCTGGTCAATATCTACGCGGCCCTGGCGGATGTTTCGCCGCA
AGTTGTTCTTGATGAACACGCCGGTGCGATGTTCGGCCATTTCAAAGTCGCGCTTGCGGATCTTGCCGTGGCCAAGCTGT
CACCGATCTCGTCCGAGATGTCCCGCCTGATGGACGACCCTGCGGAAATCGACCGTATCCTCGGCCGCGGGGCAGAGCGC
GCGCGCGCCATCACGGTCCCGATTCTGGAGCAAACCTACGACATCATCGGAATGCTCCGCAGCTAG

Upstream 100 bases:

>100_bases
CCATACCCATGGGCCCTCGGTTGACGATCCTTGCCCCCATGGGTAAGCCCGACCGCGCCGATTGGCCAGTGGGGCCATGC
GCAATCCAAGGATCGATGTC

Downstream 100 bases:

>100_bases
GACGGACCCGGGGGGCTGCCACGCAACGGCAATCACCCCCCGGCCCTCCGACCCGTTTCGCAGTCACAAGCAGTGGCCGC
GATGCGGGACTTTGCCCGCT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAETQFTPRVFSGIQPSGGLTLGNYLGAIKRFVEMQDAGTHETVYCMVDLHAITARLLSPDELRNNTRELCAGFIASGID
PEKSILINQSQVPEHAQLAWIFNCIARMGWMGRMTQWKDKSGKDAEGASLGLFAYPALMAADILVYHATHVPVGDDQKQH
LELTRDIAAKFNHDYGVEFFPITEPVIEGAATRVMNLQDGTKKMSKSDPVEKTRINMTDDADAIARKIRKAKTDPDPLPD
AVDGLAARPDARNLVNIYAALADVSPQVVLDEHAGAMFGHFKVALADLAVAKLSPISSEMSRLMDDPAEIDRILGRGAER
ARAITVPILEQTYDIIGMLRS

Sequences:

>Translated_341_residues
MAETQFTPRVFSGIQPSGGLTLGNYLGAIKRFVEMQDAGTHETVYCMVDLHAITARLLSPDELRNNTRELCAGFIASGID
PEKSILINQSQVPEHAQLAWIFNCIARMGWMGRMTQWKDKSGKDAEGASLGLFAYPALMAADILVYHATHVPVGDDQKQH
LELTRDIAAKFNHDYGVEFFPITEPVIEGAATRVMNLQDGTKKMSKSDPVEKTRINMTDDADAIARKIRKAKTDPDPLPD
AVDGLAARPDARNLVNIYAALADVSPQVVLDEHAGAMFGHFKVALADLAVAKLSPISSEMSRLMDDPAEIDRILGRGAER
ARAITVPILEQTYDIIGMLRS
>Mature_340_residues
AETQFTPRVFSGIQPSGGLTLGNYLGAIKRFVEMQDAGTHETVYCMVDLHAITARLLSPDELRNNTRELCAGFIASGIDP
EKSILINQSQVPEHAQLAWIFNCIARMGWMGRMTQWKDKSGKDAEGASLGLFAYPALMAADILVYHATHVPVGDDQKQHL
ELTRDIAAKFNHDYGVEFFPITEPVIEGAATRVMNLQDGTKKMSKSDPVEKTRINMTDDADAIARKIRKAKTDPDPLPDA
VDGLAARPDARNLVNIYAALADVSPQVVLDEHAGAMFGHFKVALADLAVAKLSPISSEMSRLMDDPAEIDRILGRGAERA
RAITVPILEQTYDIIGMLRS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=41.0876132930514, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=51.3966480446927, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1789786, Length=332, Percent_Identity=44.578313253012, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=35.1906158357771, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=35.1906158357771, Blast_Score=197, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6320474, Length=354, Percent_Identity=38.4180790960452, Blast_Score=223, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24666151, Length=321, Percent_Identity=42.0560747663551, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37357; Mature: 37226

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETQFTPRVFSGIQPSGGLTLGNYLGAIKRFVEMQDAGTHETVYCMVDLHAITARLLSP
CCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCH
DELRNNTRELCAGFIASGIDPEKSILINQSQVPEHAQLAWIFNCIARMGWMGRMTQWKDK
HHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
SGKDAEGASLGLFAYPALMAADILVYHATHVPVGDDQKQHLELTRDIAAKFNHDYGVEFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
PITEPVIEGAATRVMNLQDGTKKMSKSDPVEKTRINMTDDADAIARKIRKAKTDPDPLPD
ECCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCH
AVDGLAARPDARNLVNIYAALADVSPQVVLDEHAGAMFGHFKVALADLAVAKLSPISSEM
HHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHH
SRLMDDPAEIDRILGRGAERARAITVPILEQTYDIIGMLRS
HHHHCCHHHHHHHHCCCCHHHEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AETQFTPRVFSGIQPSGGLTLGNYLGAIKRFVEMQDAGTHETVYCMVDLHAITARLLSP
CCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCH
DELRNNTRELCAGFIASGIDPEKSILINQSQVPEHAQLAWIFNCIARMGWMGRMTQWKDK
HHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
SGKDAEGASLGLFAYPALMAADILVYHATHVPVGDDQKQHLELTRDIAAKFNHDYGVEFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
PITEPVIEGAATRVMNLQDGTKKMSKSDPVEKTRINMTDDADAIARKIRKAKTDPDPLPD
ECCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCH
AVDGLAARPDARNLVNIYAALADVSPQVVLDEHAGAMFGHFKVALADLAVAKLSPISSEM
HHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHH
SRLMDDPAEIDRILGRGAERARAITVPILEQTYDIIGMLRS
HHHHCCHHHHHHHHCCCCHHHEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]