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The map label for this gene is sdhB

Identifier: 89053295

GI number: 89053295

Start: 765756

End: 766550

Strand: Reverse

Name: sdhB

Synonym: Jann_0804

Alternate gene names: 89053295

Gene position: 766550-765756 (Counterclockwise)

Preceding gene: 89053296

Following gene: 89053293

Centisome position: 17.75

GC content: 60.63

Gene sequence:

>795_bases
ATGGTTGAACTCGCCCTCCCCAAGAACTCCCGCATCACGCGCGGCAAGACCTGGCCCAAGCCCGACGGGGCCACCAACCT
GCGCAAGTTCCAGATCTACCGCTGGAACCCCGACGACGGCAAAAACCCATCGCTGGACACCTATTGGGTCGACATGGACA
CCTGCGGGCCGATGGTTCTGGACGCGCTGATCAAGATCAAGAACGAGATTGATCCCACCCTCACCTTCCGCCGCTCCTGC
CGCGAAGGCATCTGCGGGTCCTGCGCGATGAATATCGGCGGCGTGAAATCCAAGGGCACGAACACACTGGCCTGCATCTA
CGGCATGGACGAAGTGCAGGGCGACATCGCGATTTACCCCCTGCCCCACATGCCCGTCGTCAAGGACCTGATCCCGGACC
TGACCCATTTCTACGCGCAACATGCCTCCATCATGCCGTGGCTGGAAACCAAGACCCGTCGCCCTGAAAAGGAATGGCGT
CAGTCGGTGGAAGATCGCGAAAAGCTCGACGGCCTCTACGAATGCGTCATGTGTGCCTGCTGCTCGACCTCCTGCCCGTC
CTACTGGTGGAACGGCGACCGCTATCTTGGGCCCGCCGCCCTGCTGCATGCCTACCGCTGGATCATCGACAGCCGTGACG
AGAATACGGGCGAGCGCCTGGACGAGTTGGAAGACCCCTTCAAGCTCTACCGCTGCCACACGATCATGAATTGCACGAAG
ACCTGCCCCAAAGGCCTGAACCCAGCCAAGGCGATCTCGTCGATCAAGAAAATGATGGTCGAACGGACGCACTGA

Upstream 100 bases:

>100_bases
ATTCGCGCGGCCGTCCTGCGACCATCCGCGCGCGCGCGAAGGCTTCCCGTCGCGGGTCACAGGCCATAGGTTCAACTGGA
CGGAATGAACGGATTTTCCC

Downstream 100 bases:

>100_bases
CCTCTGCAATGGTGTCTTCAAGCCTTCGAAGACACGGTAAAACTAGCCGAGGCTTTGAATCGTCTCGGCCTTTCATGAGC
GTGGCCGAAGACCATTCCCC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MVELALPKNSRITRGKTWPKPDGATNLRKFQIYRWNPDDGKNPSLDTYWVDMDTCGPMVLDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIGGVKSKGTNTLACIYGMDEVQGDIAIYPLPHMPVVKDLIPDLTHFYAQHASIMPWLETKTRRPEKEWR
QSVEDREKLDGLYECVMCACCSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDENTGERLDELEDPFKLYRCHTIMNCTK
TCPKGLNPAKAISSIKKMMVERTH

Sequences:

>Translated_264_residues
MVELALPKNSRITRGKTWPKPDGATNLRKFQIYRWNPDDGKNPSLDTYWVDMDTCGPMVLDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIGGVKSKGTNTLACIYGMDEVQGDIAIYPLPHMPVVKDLIPDLTHFYAQHASIMPWLETKTRRPEKEWR
QSVEDREKLDGLYECVMCACCSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDENTGERLDELEDPFKLYRCHTIMNCTK
TCPKGLNPAKAISSIKKMMVERTH
>Mature_264_residues
MVELALPKNSRITRGKTWPKPDGATNLRKFQIYRWNPDDGKNPSLDTYWVDMDTCGPMVLDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIGGVKSKGTNTLACIYGMDEVQGDIAIYPLPHMPVVKDLIPDLTHFYAQHASIMPWLETKTRRPEKEWR
QSVEDREKLDGLYECVMCACCSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDENTGERLDELEDPFKLYRCHTIMNCTK
TCPKGLNPAKAISSIKKMMVERTH

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=241, Percent_Identity=66.804979253112, Blast_Score=341, Evalue=4e-94,
Organism=Escherichia coli, GI1786943, Length=240, Percent_Identity=51.6666666666667, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1790596, Length=229, Percent_Identity=31.4410480349345, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17533915, Length=241, Percent_Identity=62.655601659751, Blast_Score=323, Evalue=8e-89,
Organism=Saccharomyces cerevisiae, GI6322987, Length=237, Percent_Identity=62.4472573839662, Blast_Score=311, Evalue=7e-86,
Organism=Drosophila melanogaster, GI17137106, Length=250, Percent_Identity=64.8, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24643156, Length=238, Percent_Identity=63.0252100840336, Blast_Score=320, Evalue=6e-88,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 30216; Mature: 30216

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELALPKNSRITRGKTWPKPDGATNLRKFQIYRWNPDDGKNPSLDTYWVDMDTCGPMVL
CEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
DALIKIKNEIDPTLTFRRSCREGICGSCAMNIGGVKSKGTNTLACIYGMDEVQGDIAIYP
HHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEECHHHHCCCEEEEE
LPHMPVVKDLIPDLTHFYAQHASIMPWLETKTRRPEKEWRQSVEDREKLDGLYECVMCAC
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDENTGERLDELEDPFKLYRCHTIMNCTK
HCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TCPKGLNPAKAISSIKKMMVERTH
HCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVELALPKNSRITRGKTWPKPDGATNLRKFQIYRWNPDDGKNPSLDTYWVDMDTCGPMVL
CEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
DALIKIKNEIDPTLTFRRSCREGICGSCAMNIGGVKSKGTNTLACIYGMDEVQGDIAIYP
HHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEECHHHHCCCEEEEE
LPHMPVVKDLIPDLTHFYAQHASIMPWLETKTRRPEKEWRQSVEDREKLDGLYECVMCAC
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDENTGERLDELEDPFKLYRCHTIMNCTK
HCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TCPKGLNPAKAISSIKKMMVERTH
HCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA