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The map label for this gene is dppA [H]

Identifier: 89053273

GI number: 89053273

Start: 742293

End: 743777

Strand: Reverse

Name: dppA [H]

Synonym: Jann_0782

Alternate gene names: 89053273

Gene position: 743777-742293 (Counterclockwise)

Preceding gene: 89053274

Following gene: 89053272

Centisome position: 17.23

GC content: 64.38

Gene sequence:

>1485_bases
ATGACATCCACCCCCCTATCGACATTGCGCCTGAGCGCCGCCGTGTTGGCGCTGACAGCGGGCGCTGCAATGGCGCAGCA
GACATCGATCACCATCGGAATGCAGCTGGAGCCGCCGATGCTGGACCCCACGGGCGGGGCTGCGGCGGCGATTGACGAGG
TCGTCTATTCCAACGTGTTCGAGGGGCTGACGCGCTTTGCCGCCGATGGGTCCGTCGTTCCCGGGCTGGCGGAGTCGTGG
GAGATTTCCGAAGACGGCACCGTTTATACCTTCACCTTGCGGGACGGCGTCACCTTCCATGACGGGGCTGCGATGACCGC
CGAGGATGTTGTGTTCAGCCTCGACCGTGCACGCGCCGAAGGCTCCACCAACGCGCAGGCGGCGCTGTTTGCCAATATCG
TCAGCGTCGAGGCCGTGGATGACACCACCGCCGTGGTCACGCTGGACGGGCCCGACGGCGCGTTCCTGTTCGACATGGCC
TGGGGCGACGCGGTGATCGTGGACGCGGCCAGCGCGGAGAATAACGCCACAAACCCCATTGGTACCGGCGCGTTTGCGTT
CAGCGAATGGCGGCAGGGCGACAGCGTGATGCTGACCCGCAACGACAATTACTGGGGCGAGCCCGCCGCGCTGACGGACG
TGACCTTCCGCTTCATCAGTGACCCCAACGCGGCGCTCGCGGCGATGATGGCGGGCGATGTGGATGCCTTCCCGGTCTTC
CCCGCCCCTGAAAACCTTGCGCAGTTCGAGGCCGACCCCCGGTTCAACGTCATCGTCGGCTCCACCGAGGGGGAAACCAT
TCTGGCGATGAACAACGAGGCGGAGGCGCTGGCCGATCCGCTGGTGCGGCAGGCGATCACCCATGCGATCAACCGCCAAG
ACATCATCGACGGCGCGATGTTTGGCTATGGCACGCCCATCGGCACCCACTTCGCGCCGCACAATCCCGATTACGTGGAC
CTGACGGGGCAATCGGCGTTTGACCCGGACCGGGCGCGCGAATTGCTGGCCGAGGCGGGTGCGGAGGACCTGACCCTGCG
CCTGATGCTGCCACCGCCGTCCTATGCGCGGCGCGGCGGGGAAATCATCGCCAGCCAGTTGCGGGACGTCGGCATCGCCA
CGGAAATCACCAATCTGGAATGGGCCGGATGGCTGGAACAGGTGTTCCGCGGCTATGATTTCGACCTGACGATTGTCAGC
CATACGGAACCTGCGGACATCAACATCTACGCCCGGCCGGAGTATTATTTCCAATACGACAATGCGGAGTTTCAGGGCCT
GATGGAGGATTTGTCGGTCACCACCGACCCGGCTGAACGCACGGCGATCAACCAGCAGGCCCAACAGATGATCGCCGATG
ATTACGTCAACGCCTATCTCTTCCAGCTGGCCAAGACCGGTGTCGCCAACGCGGGCATTGAGGGTCTGTGGGAAAACGCG
CCGACCCAGGCCAATGACCTGACGGCGGTGCGCTGGACGCAGTAG

Upstream 100 bases:

>100_bases
GCCCGGGCAAAGGTCCACGCGGGGCGGCGGTAACTTTTGGGTAGGCGAACGCGCTGGCCTGCGGCACACTGACCGCAAAA
CGTCCAACGGGAGAGACATC

Downstream 100 bases:

>100_bases
GCCCAGCGCGCCATCTGTCATCATGCTGTCATCGGCGTCCGGGTATCTGGGCGCCGAACGCGTTTGACCCTACAGGATAC
CGCCCCCATGCCCCGCACGC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MTSTPLSTLRLSAAVLALTAGAAMAQQTSITIGMQLEPPMLDPTGGAAAAIDEVVYSNVFEGLTRFAADGSVVPGLAESW
EISEDGTVYTFTLRDGVTFHDGAAMTAEDVVFSLDRARAEGSTNAQAALFANIVSVEAVDDTTAVVTLDGPDGAFLFDMA
WGDAVIVDAASAENNATNPIGTGAFAFSEWRQGDSVMLTRNDNYWGEPAALTDVTFRFISDPNAALAAMMAGDVDAFPVF
PAPENLAQFEADPRFNVIVGSTEGETILAMNNEAEALADPLVRQAITHAINRQDIIDGAMFGYGTPIGTHFAPHNPDYVD
LTGQSAFDPDRARELLAEAGAEDLTLRLMLPPPSYARRGGEIIASQLRDVGIATEITNLEWAGWLEQVFRGYDFDLTIVS
HTEPADINIYARPEYYFQYDNAEFQGLMEDLSVTTDPAERTAINQQAQQMIADDYVNAYLFQLAKTGVANAGIEGLWENA
PTQANDLTAVRWTQ

Sequences:

>Translated_494_residues
MTSTPLSTLRLSAAVLALTAGAAMAQQTSITIGMQLEPPMLDPTGGAAAAIDEVVYSNVFEGLTRFAADGSVVPGLAESW
EISEDGTVYTFTLRDGVTFHDGAAMTAEDVVFSLDRARAEGSTNAQAALFANIVSVEAVDDTTAVVTLDGPDGAFLFDMA
WGDAVIVDAASAENNATNPIGTGAFAFSEWRQGDSVMLTRNDNYWGEPAALTDVTFRFISDPNAALAAMMAGDVDAFPVF
PAPENLAQFEADPRFNVIVGSTEGETILAMNNEAEALADPLVRQAITHAINRQDIIDGAMFGYGTPIGTHFAPHNPDYVD
LTGQSAFDPDRARELLAEAGAEDLTLRLMLPPPSYARRGGEIIASQLRDVGIATEITNLEWAGWLEQVFRGYDFDLTIVS
HTEPADINIYARPEYYFQYDNAEFQGLMEDLSVTTDPAERTAINQQAQQMIADDYVNAYLFQLAKTGVANAGIEGLWENA
PTQANDLTAVRWTQ
>Mature_493_residues
TSTPLSTLRLSAAVLALTAGAAMAQQTSITIGMQLEPPMLDPTGGAAAAIDEVVYSNVFEGLTRFAADGSVVPGLAESWE
ISEDGTVYTFTLRDGVTFHDGAAMTAEDVVFSLDRARAEGSTNAQAALFANIVSVEAVDDTTAVVTLDGPDGAFLFDMAW
GDAVIVDAASAENNATNPIGTGAFAFSEWRQGDSVMLTRNDNYWGEPAALTDVTFRFISDPNAALAAMMAGDVDAFPVFP
APENLAQFEADPRFNVIVGSTEGETILAMNNEAEALADPLVRQAITHAINRQDIIDGAMFGYGTPIGTHFAPHNPDYVDL
TGQSAFDPDRARELLAEAGAEDLTLRLMLPPPSYARRGGEIIASQLRDVGIATEITNLEWAGWLEQVFRGYDFDLTIVSH
TEPADINIYARPEYYFQYDNAEFQGLMEDLSVTTDPAERTAINQQAQQMIADDYVNAYLFQLAKTGVANAGIEGLWENAP
TQANDLTAVRWTQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=495, Percent_Identity=27.0707070707071, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789887, Length=295, Percent_Identity=33.2203389830508, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787052, Length=473, Percent_Identity=28.5412262156448, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787762, Length=502, Percent_Identity=26.8924302788845, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1787551, Length=311, Percent_Identity=28.6173633440514, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87081878, Length=462, Percent_Identity=27.0562770562771, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1787495, Length=506, Percent_Identity=25.098814229249, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789397, Length=472, Percent_Identity=25.635593220339, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082063, Length=323, Percent_Identity=23.2198142414861, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 53072; Mature: 52941

Theoretical pI: Translated: 3.77; Mature: 3.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPLSTLRLSAAVLALTAGAAMAQQTSITIGMQLEPPMLDPTGGAAAAIDEVVYSNVF
CCCCCHHHHHHHHHHHHHHHCHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
EGLTRFAADGSVVPGLAESWEISEDGTVYTFTLRDGVTFHDGAAMTAEDVVFSLDRARAE
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHCC
GSTNAQAALFANIVSVEAVDDTTAVVTLDGPDGAFLFDMAWGDAVIVDAASAENNATNPI
CCCCCHHHHEEEEEEEEEECCCEEEEEEECCCCCEEEEECCCCEEEEEECCCCCCCCCCC
GTGAFAFSEWRQGDSVMLTRNDNYWGEPAALTDVTFRFISDPNAALAAMMAGDVDAFPVF
CCCHHHHHHHCCCCEEEEEECCCCCCCCCCHHHEEEEEECCCCHHHHHHHHCCCCCCCCC
PAPENLAQFEADPRFNVIVGSTEGETILAMNNEAEALADPLVRQAITHAINRQDIIDGAM
CCCCHHHHCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHCCHH
FGYGTPIGTHFAPHNPDYVDLTGQSAFDPDRARELLAEAGAEDLTLRLMLPPPSYARRGG
HCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCH
EIIASQLRDVGIATEITNLEWAGWLEQVFRGYDFDLTIVSHTEPADINIYARPEYYFQYD
HHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEEEC
NAEFQGLMEDLSVTTDPAERTAINQQAQQMIADDYVNAYLFQLAKTGVANAGIEGLWENA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
PTQANDLTAVRWTQ
CCCCCCEEEEEECC
>Mature Secondary Structure 
TSTPLSTLRLSAAVLALTAGAAMAQQTSITIGMQLEPPMLDPTGGAAAAIDEVVYSNVF
CCCCHHHHHHHHHHHHHHHCHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
EGLTRFAADGSVVPGLAESWEISEDGTVYTFTLRDGVTFHDGAAMTAEDVVFSLDRARAE
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHCC
GSTNAQAALFANIVSVEAVDDTTAVVTLDGPDGAFLFDMAWGDAVIVDAASAENNATNPI
CCCCCHHHHEEEEEEEEEECCCEEEEEEECCCCCEEEEECCCCEEEEEECCCCCCCCCCC
GTGAFAFSEWRQGDSVMLTRNDNYWGEPAALTDVTFRFISDPNAALAAMMAGDVDAFPVF
CCCHHHHHHHCCCCEEEEEECCCCCCCCCCHHHEEEEEECCCCHHHHHHHHCCCCCCCCC
PAPENLAQFEADPRFNVIVGSTEGETILAMNNEAEALADPLVRQAITHAINRQDIIDGAM
CCCCHHHHCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHCCHH
FGYGTPIGTHFAPHNPDYVDLTGQSAFDPDRARELLAEAGAEDLTLRLMLPPPSYARRGG
HCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHCCH
EIIASQLRDVGIATEITNLEWAGWLEQVFRGYDFDLTIVSHTEPADINIYARPEYYFQYD
HHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEEEC
NAEFQGLMEDLSVTTDPAERTAINQQAQQMIADDYVNAYLFQLAKTGVANAGIEGLWENA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
PTQANDLTAVRWTQ
CCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]