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The map label for this gene is siaP [H]

Identifier: 89053152

GI number: 89053152

Start: 631686

End: 632711

Strand: Direct

Name: siaP [H]

Synonym: Jann_0661

Alternate gene names: 89053152

Gene position: 631686-632711 (Clockwise)

Preceding gene: 89053150

Following gene: 89053153

Centisome position: 14.63

GC content: 65.01

Gene sequence:

>1026_bases
ATGAAGACGAAACTTTTGATGACGACAGTCGCGGCAGGCGCGATGGTGGCCTCGGGCGCATTGGCGCAGGAGGTGACGCT
GCGCCTGCACCAGTTCCTGCCTGCGCAAGCCAATGTGCCCGCGCTGGTGCTGGACGTGTGGGCCGATCAGGTTGAGGAAG
CCTCTGGCGGACGCATCGAGATCGAGCGCTATCCGTCGATGCAGCTGGGCGGCTCGCCGCCAGAACTGATGGATCAGGCC
GTGGATGGCGTGGCCGATATCGTCTGGACCGTGGTCGGCTACACGCCGGGCCGCTTCCCGAGCACTGAAGTGTTCGAGCT
GCCGTTCATGGTCGCTGATGCCCGCGCCGCGTCCTGCGCCTATTGGACGATGTATGAAGAGGGGATGCAGGAGGAATTCT
CCTCCGTGCACCTGCTGGGCACCTGGGTCCACGGGCCGGGCATGTTCCACACGGCGGATCCGGTTGAGGTTCCAAGCGAC
CTTGAGGGGATGCAGATCCGCGGCGGATCGCGGCTTGTGAACCAGTTGCTGGAGCTGACAGGCGCCACGCCCGTGGGCAT
GCCCGTTCCCGCCGTGCCGGAAGCGCTGTCGCGTGGCACGATTGACGGCACCACGATCCCGTGGGAAGTCACAGCCGCCC
TGCGCGTGCCGGAACTGGTGGAAAACCACACCGGGTTCGAGGGCAATGGGCTGTATACGCTGACCTTCGTGCTGGCGATG
AACAACGATGCCTACGACGCGATGCCAGAGGATCTGCAACAGATCCTGGACGACAATTCTGGTCTGGAATTCTCCATCTT
CGCGGGTGGCACCCAGGCCGACGCCGATGGTCCGGCGCGCGAGCTGGCGGTGGATGCGGGCAACAACATCATCATGATCG
ACGCGGCCACGGCCGAGGCCGAATGGCTGCCGGTTGTGGGCCCGATCTACGACACGTGGATCGCGGATGTTGCCGAAAGT
GGGCTGGACGGCCAGGCGCTGATCGACCGGGCGCGGGAGCTGATGTCCGGGCAATGCGCGGGCTGA

Upstream 100 bases:

>100_bases
ATCAATTCATCTTGCGGTTGAGCTCTTCGGACTTGGCTGCGCATGGTTCGGGATAAGGCGGTGCACCCGTCAGCGAACAC
TCACTGGGAGGAAGATCAAC

Downstream 100 bases:

>100_bases
ATGCCTGAGACGATAGGGGCCGCGGCGGGACACCTGCCGCGGCCCTTTTTCTAACCATGGTCCAGGATATCCCATGCACC
GCGCGTTAACGTATTTATCC

Product: TRAP dicarboxylate transporter subunit DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKTKLLMTTVAAGAMVASGALAQEVTLRLHQFLPAQANVPALVLDVWADQVEEASGGRIEIERYPSMQLGGSPPELMDQA
VDGVADIVWTVVGYTPGRFPSTEVFELPFMVADARAASCAYWTMYEEGMQEEFSSVHLLGTWVHGPGMFHTADPVEVPSD
LEGMQIRGGSRLVNQLLELTGATPVGMPVPAVPEALSRGTIDGTTIPWEVTAALRVPELVENHTGFEGNGLYTLTFVLAM
NNDAYDAMPEDLQQILDDNSGLEFSIFAGGTQADADGPARELAVDAGNNIIMIDAATAEAEWLPVVGPIYDTWIADVAES
GLDGQALIDRARELMSGQCAG

Sequences:

>Translated_341_residues
MKTKLLMTTVAAGAMVASGALAQEVTLRLHQFLPAQANVPALVLDVWADQVEEASGGRIEIERYPSMQLGGSPPELMDQA
VDGVADIVWTVVGYTPGRFPSTEVFELPFMVADARAASCAYWTMYEEGMQEEFSSVHLLGTWVHGPGMFHTADPVEVPSD
LEGMQIRGGSRLVNQLLELTGATPVGMPVPAVPEALSRGTIDGTTIPWEVTAALRVPELVENHTGFEGNGLYTLTFVLAM
NNDAYDAMPEDLQQILDDNSGLEFSIFAGGTQADADGPARELAVDAGNNIIMIDAATAEAEWLPVVGPIYDTWIADVAES
GLDGQALIDRARELMSGQCAG
>Mature_341_residues
MKTKLLMTTVAAGAMVASGALAQEVTLRLHQFLPAQANVPALVLDVWADQVEEASGGRIEIERYPSMQLGGSPPELMDQA
VDGVADIVWTVVGYTPGRFPSTEVFELPFMVADARAASCAYWTMYEEGMQEEFSSVHLLGTWVHGPGMFHTADPVEVPSD
LEGMQIRGGSRLVNQLLELTGATPVGMPVPAVPEALSRGTIDGTTIPWEVTAALRVPELVENHTGFEGNGLYTLTFVLAM
NNDAYDAMPEDLQQILDDNSGLEFSIFAGGTQADADGPARELAVDAGNNIIMIDAATAEAEWLPVVGPIYDTWIADVAES
GLDGQALIDRARELMSGQCAG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36382; Mature: 36382

Theoretical pI: Translated: 3.82; Mature: 3.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLLMTTVAAGAMVASGALAQEVTLRLHQFLPAQANVPALVLDVWADQVEEASGGRIE
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCEEE
IERYPSMQLGGSPPELMDQAVDGVADIVWTVVGYTPGRFPSTEVFELPFMVADARAASCA
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEECCEEEECCCCCCEE
YWTMYEEGMQEEFSSVHLLGTWVHGPGMFHTADPVEVPSDLEGMQIRGGSRLVNQLLELT
EHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHH
GATPVGMPVPAVPEALSRGTIDGTTIPWEVTAALRVPELVENHTGFEGNGLYTLTFVLAM
CCCCCCCCCCCHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEE
NNDAYDAMPEDLQQILDDNSGLEFSIFAGGTQADADGPARELAVDAGNNIIMIDAATAEA
CCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHEEEECCCCEEEEEECCCCC
EWLPVVGPIYDTWIADVAESGLDGQALIDRARELMSGQCAG
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTKLLMTTVAAGAMVASGALAQEVTLRLHQFLPAQANVPALVLDVWADQVEEASGGRIE
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCEEE
IERYPSMQLGGSPPELMDQAVDGVADIVWTVVGYTPGRFPSTEVFELPFMVADARAASCA
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEECCEEEECCCCCCEE
YWTMYEEGMQEEFSSVHLLGTWVHGPGMFHTADPVEVPSDLEGMQIRGGSRLVNQLLELT
EHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHH
GATPVGMPVPAVPEALSRGTIDGTTIPWEVTAALRVPELVENHTGFEGNGLYTLTFVLAM
CCCCCCCCCCCHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEE
NNDAYDAMPEDLQQILDDNSGLEFSIFAGGTQADADGPARELAVDAGNNIIMIDAATAEA
CCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHEEEECCCCEEEEEECCCCC
EWLPVVGPIYDTWIADVAESGLDGQALIDRARELMSGQCAG
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA