Click here to switch to the map view.

The map label for this gene is era

Identifier: 89053015

GI number: 89053015

Start: 515450

End: 516388

Strand: Direct

Name: era

Synonym: Jann_0524

Alternate gene names: 89053015

Gene position: 515450-516388 (Clockwise)

Preceding gene: 89053013

Following gene: 89053016

Centisome position: 11.94

GC content: 61.77

Gene sequence:

>939_bases
ATGATGCAAAGGCCGCTTCCCATGACTGACCCCACCACCCGCGCCGGGTTCATCGCCCTGATAGGGGAGCCCAATGCAGG
CAAATCCACGCTGCTCAACCGGATGGTGGGTGCGAAGGTCTCGATCGTGACGCACAAGGTGCAGACCACGCGGGCGCGGA
TCCGGGGGGTGGCGATGGAGGGTGACAGCCAGCTGGTGTTTGTGGACACGCCGGGCCTCTTCCGTCCGCGCCGTCGGTTG
GACCGGGCGATGGTCAAAGCCGCCTGGACGGGAGCGGCGGACGCCGATGTCGTGGTGCTTCTGATCGAGGCGCACCGGGG
CCTGACCGATGGGGTCCAGGCTATCCTGGATGGTCTGAAAGAGCGGACCGGGGACCGCAAGGTCGCGCTGGCCATCAACA
AGATTGACCGGGTCGATGCGCCGGTTCTGCTGAAGCTGACCGAAGACCTAAACGCCGCCTACCCGTTTGATGAAACTTAC
ATGATCTCTGCGGAGAAGGGCCATGGGGTGAAAGAGCTTCGCACCTGGCTCGCCGCTGAAGTTCCCGAAGGTCCCTGGCT
TTATCCCGAAGACCAGATTGCTGATTTGCCGCTGCGGATGATCGCGGCAGAAATGACGCGTGAGAAGCTGACCCTGCGCC
TGCATCAGGAATTGCCCTATCAGCTGACCGTGGAGACGGAGGCGTGGGAAAACCGCAGGGACGGCTCTGCCAAGATCGAC
CAGATCATCTATGTGGCACGCGATGGCCATAAGGGGATCCTGCTGGGCAAGGGCGGCGAGACGATCAAATCCGTTTCCAA
AGCCGCGCGGGAGGAGATCGCGGAATTTGTGGGCCACCCGGTGCACCTGTTTCTGCAGGTGAAGGTCCGGCCCGGTTGGT
TGGAGGAATCTGAGCGCTACTCGGAAATGGGCCTCAACTTCAAAGACGGAAATGCATGA

Upstream 100 bases:

>100_bases
GCGCAAGCGGGGCACGGGCGGCCTAGTTCCGACACCTGATTGACCCGCGCGTTAACGCCTTTGCACGCGACATTATTGGC
GATAGAGAAGCGATCTGGAC

Downstream 100 bases:

>100_bases
GTGCGCGGCTGACCGCAGACTTCTGGGTTGCGGCCTATCTTGCGCGGCTGCGGGTGGAGGACATTCCGGCCTTCATCGTC
TCGCGCGGTGATGGCACCGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MMQRPLPMTDPTTRAGFIALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQLVFVDTPGLFRPRRRL
DRAMVKAAWTGAADADVVVLLIEAHRGLTDGVQAILDGLKERTGDRKVALAINKIDRVDAPVLLKLTEDLNAAYPFDETY
MISAEKGHGVKELRTWLAAEVPEGPWLYPEDQIADLPLRMIAAEMTREKLTLRLHQELPYQLTVETEAWENRRDGSAKID
QIIYVARDGHKGILLGKGGETIKSVSKAAREEIAEFVGHPVHLFLQVKVRPGWLEESERYSEMGLNFKDGNA

Sequences:

>Translated_312_residues
MMQRPLPMTDPTTRAGFIALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQLVFVDTPGLFRPRRRL
DRAMVKAAWTGAADADVVVLLIEAHRGLTDGVQAILDGLKERTGDRKVALAINKIDRVDAPVLLKLTEDLNAAYPFDETY
MISAEKGHGVKELRTWLAAEVPEGPWLYPEDQIADLPLRMIAAEMTREKLTLRLHQELPYQLTVETEAWENRRDGSAKID
QIIYVARDGHKGILLGKGGETIKSVSKAAREEIAEFVGHPVHLFLQVKVRPGWLEESERYSEMGLNFKDGNA
>Mature_312_residues
MMQRPLPMTDPTTRAGFIALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQLVFVDTPGLFRPRRRL
DRAMVKAAWTGAADADVVVLLIEAHRGLTDGVQAILDGLKERTGDRKVALAINKIDRVDAPVLLKLTEDLNAAYPFDETY
MISAEKGHGVKELRTWLAAEVPEGPWLYPEDQIADLPLRMIAAEMTREKLTLRLHQELPYQLTVETEAWENRRDGSAKID
QIIYVARDGHKGILLGKGGETIKSVSKAAREEIAEFVGHPVHLFLQVKVRPGWLEESERYSEMGLNFKDGNA

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=326, Percent_Identity=27.9141104294479, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=38.7959866220736, Blast_Score=197, Evalue=5e-52,
Organism=Escherichia coli, GI87082120, Length=172, Percent_Identity=33.1395348837209, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646434, Length=313, Percent_Identity=25.8785942492013, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34709; Mature: 34709

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQRPLPMTDPTTRAGFIALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAME
CCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEEHHHHHHHHHEEEEEE
GDSQLVFVDTPGLFRPRRRLDRAMVKAAWTGAADADVVVLLIEAHRGLTDGVQAILDGLK
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
ERTGDRKVALAINKIDRVDAPVLLKLTEDLNAAYPFDETYMISAEKGHGVKELRTWLAAE
HCCCCCEEEEEEEHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHC
VPEGPWLYPEDQIADLPLRMIAAEMTREKLTLRLHQELPYQLTVETEAWENRRDGSAKID
CCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHEECCCCCEEEEEECHHHCCCCCCCCCEE
QIIYVARDGHKGILLGKGGETIKSVSKAAREEIAEFVGHPVHLFLQVKVRPGWLEESERY
EEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHH
SEMGLNFKDGNA
HHCCCCCCCCCC
>Mature Secondary Structure
MMQRPLPMTDPTTRAGFIALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAME
CCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEEHHHHHHHHHEEEEEE
GDSQLVFVDTPGLFRPRRRLDRAMVKAAWTGAADADVVVLLIEAHRGLTDGVQAILDGLK
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
ERTGDRKVALAINKIDRVDAPVLLKLTEDLNAAYPFDETYMISAEKGHGVKELRTWLAAE
HCCCCCEEEEEEEHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHC
VPEGPWLYPEDQIADLPLRMIAAEMTREKLTLRLHQELPYQLTVETEAWENRRDGSAKID
CCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHEECCCCCEEEEEECHHHCCCCCCCCCEE
QIIYVARDGHKGILLGKGGETIKSVSKAAREEIAEFVGHPVHLFLQVKVRPGWLEESERY
EEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHH
SEMGLNFKDGNA
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA